Download or read book Comparative Pathology Bulletin written by and published by . This book was released on 1992 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-06-03 with total page 4609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Download or read book Society of Toxicologic Pathology s 27th Annual Symposium written by Society of Toxicologic Pathology and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tactics in Contemporary Drug Design written by Nicholas A. Meanwell and published by Springer. This book was released on 2014-12-08 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1576 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Examining the Current State of Cosmetics written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and published by . This book was released on 2013 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunopathology in Toxicology and Drug Development written by George A. Parker and published by Springer. This book was released on 2017-03-28 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology
Download or read book Science written by John Michels (Journalist) and published by . This book was released on 2003 with total page 1236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book 1997 Annual Meeting written by American College of Veterinary Pathologists. Meeting and published by . This book was released on 1997 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Haschek and Rousseaux s Handbook of Toxicologic Pathology written by Wanda M. Haschek and published by Elsevier. This book was released on 2001-10-16 with total page 2160 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed
Download or read book Creating an Ecological Society written by Fred Magdoff and published by NYU Press. This book was released on 2017-05-29 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickened by the contamination of their water, their air, of the Earth itself, more and more people are coming to realize that it is capitalism that is, quite literally, killing them. It is now clearer than ever that capitalism is also degrading the Earth’s ability to support other forms of life. Capitalism’s imperative—to make profit at all costs and expand without end—is destabilizing Earth’s climate, while increasing human misery and inequality on a planetary scale. Already, hundreds of millions of people are facing poverty in the midst of untold wealth, perpetual war, growing racism, and gender oppression. The need to organize for social and environmental reforms has never been greater. But crucial as reforms are, they cannot solve our intertwined ecological and social crises. Creating an Ecological Society reveals an overwhelmingly simple truth: Fighting for reforms is vital, but revolution is essential. Because it aims squarely at replacing capitalism with an ecologically sound and socially just society, Creating an Ecological Society is filled with revolutionary hope. Fred Magdoff and Chris Williams, who have devoted their lives to activism, Marxist analysis, and ecological science, provide informed, fascinating accounts of how a new world can be created from the ashes of the old. Their book shows that it is possible to envision and create a society that is genuinely democratic, equitable, and ecologically sustainable. And possible—not one moment too soon—for society to change fundamentally and be brought into harmony with nature.
Download or read book Newsletter written by and published by . This book was released on 1999 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index of Conference Proceedings Received written by British Library. Lending Division and published by . This book was released on 1987 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
