Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2018-08-14 with total page 1776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the success of the first edition, this book is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk. Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new concept chapters. The first of the new chapters address approaches for the evaluation of unique therapeutic modalities such as cell therapies, gene therapies, and gene expression knockdown therapies. While these still represent new developing therapeutic approaches, there has been significant experience with the therapeutic modalities in the last 5 years. The second new chapter addresses the nonclinical safety assessment of medical devices, a topic of increasing importance that was not addressed in a unique chapter in the first edition. The other concept chapters have been updated and cover important topics including the overview of drug development; principles of nonclinical safety assessment; an introduction to toxicologic pathology; techniques used in toxicologic pathology, clinical pathology, toxicokinetics, and drug development toxicogenomics; and spontaneous lesions. The 13 organ system chapters provide the specifics related to pathologic characteristics, differential diagnosis, and interpretation of toxic responses in each organ system. These chapters are specifically important for the bench pathologist but also for the toxicologist who interacts with pathologists and function as study toxicologists and project team representatives in the drug development arena.
Download or read book Immunopathology in Toxicology and Drug Development written by George A. Parker and published by Springer. This book was released on 2017-03-28 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Science written by John Michels (Journalist) and published by . This book was released on 2003 with total page 1236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology
Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2003 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Behaviour Problems in Children and Adolescents written by Vimala Veeraraghavan and published by Northern Book Centre. This book was released on 2006 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Behaviour Problems in Children and Adolescents – A guide to Parents, Teachers and Mental Health Professional†is a sequel to Teenage Blues written by the author and Dr. Shalini Singh which was published by Mosaic in the year 2000. Deals with some of the more serious behaviour problems coming under the category of psychiatric disorders in children and adolescents. For example this book deals with these commonly observed but relatively more serious problems which include anxiety disorders, phobias, obsessive compulsive disorders, conduct disorders, attention deficit hyperactivity disorders, autism spectrum disorders, schizophrenia, depression, stammering etc. The book emphasises on a thorough assessment through correct diagnosis and effective management. This book attempts to help parents and teachers identify symptoms of the various disorders, so that the same could be handled right at the onset and effectively. “Tips to parents†draws attention towards not only easily identifying the symptoms but highlights comprehensive assessment, treatment as well as prevention. The cases presented as vignettes give a peep into the gamut of treatment available for these disorders and how children in the present day can be helped to come back to normalcy. The book will be of value to parents, teachers and counsellors. It would also be useful to school social workers, school psychologists, child mental health specialists, students of clinical psychology, child guidance workers, and others who are working in the field of children and adolescents, who all are referred children with different types of behaviour problems.
Download or read book Veterinary and Human Toxicology written by and published by . This book was released on 2002 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Society of Toxicologic Pathology s 26th Annual Symposium written by Society of Toxicologic Pathology and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Zoological Record written by and published by . This book was released on 1870 with total page 1480 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Congress Calendar written by and published by . This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition Abstracts and Reviews written by and published by . This book was released on 1967 with total page 1524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index of Conference Proceedings Received written by British Library. Lending Division and published by . This book was released on 1988 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1980 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Newsletter written by and published by . This book was released on 1999 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ILAR News written by and published by . This book was released on 1976 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
