Download or read book Smart Drug Delivery System written by Ali Demir Sezer and published by BoD – Books on Demand. This book was released on 2016-02-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
Download or read book Organic Materials as Smart Nanocarriers for Drug Delivery written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-03-26 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. - Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery - Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery - Assesses how molecular organic frameworks lead to more effective drug delivery systems
Download or read book Drug Targeting and Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-21 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Download or read book Modeling and Control of Drug Delivery Systems written by Ahmad Taher Azar and published by Academic Press. This book was released on 2021-02-06 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. - Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring - Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area - Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS
Download or read book Silk based Drug Delivery Systems written by Elia Bari and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.
Download or read book Stimuli responsive Drug Delivery Systems written by Amit Singh and published by Royal Society of Chemistry. This book was released on 2018-07-09 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.
Download or read book Smart Drug Delivery Systems written by and published by BoD – Books on Demand. This book was released on 2024-08-21 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapeutic strategies are fundamental for treating diseases like cancer, which metastasizes rapidly to healthy tissues. However, these drugs, being nonspecific, may harm both the diseased as well as the healthy tissues. Rapid clearance, low uptake, and uneven distribution of the payloads at target sites result in poor biodistribution. To address the emerging challenges of off-target accumulation and patient noncompliance, it is crucial to selectively deliver therapeutic agents to target sites, release the loaded cargo efficiently, and remove the chemotherapeutic agents from the system without triggering an immune response. The advent of smart targeting methods has revolutionized drug delivery systems (DDS). Stimuli-responsive smart DDS can release drugs in response to pH, light, redox, magnetic fields, and hyperthermia, marking the future of translational medicine. Exosomes and phytosomes are innovative drug delivery platforms that have brought about a paradigm shift in DDS. Theranostic agents, which combine diagnostic and therapeutic functions, represent a significant advancement in personalized medicine. These agents allow real-time assessment of drug biodistribution, release, and therapeutic outcomes. Theranostic probes, particularly nanoparticles with drug carrier and imaging capabilities, have transformed cancer therapy by enabling precise imaging at tumor sites. This book explores drug delivery strategies for therapeutic products including vitamins, emphasizing the delivery of live cell therapies. It also highlights nanostructured systems tailored for smart drug delivery and theranostic medicines, showcasing promising advancements in this emerging field.
Download or read book Smart Drug Delivery written by Usama Ahmad and published by BoD – Books on Demand. This book was released on 2022-07-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together recent developments in the field of drug delivery. Technological advancements in the field of pharmaceutical sciences have revolutionized the patient care industry. The book serves to bridge the gap between the current research scenario and the technical knowledge provided at the pharmaceutical institutions to maximize the skills of individuals involved at any level in this domain. Chapters address topics related to the formulation and evaluation of drug delivery systems, various targeting approaches and novel tools, and design and statistical techniques employed to develop robust and effective dosage forms.
Download or read book Smart Materials for Drug Delivery written by Carmen Alvarez-Lorenzo and published by Royal Society of Chemistry. This book was released on 2013-04-25 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart materials, which can change properties when an external stimulus is applied, can be used for the targeted drug delivery of an active molecule to a specific site in the correct dosage. Different materials such as liposomes, polymeric systems, nanomaterials and hydrogels can respond to different stimuli such as pH, temperature and light and these are all attractive for controlled release applications. With so many papers available on smart and stimuli-responsive materials for drug delivery applications it's hard to know where to start reading about this exciting topic. This two volume set brings together the recent findings in the area and provides a critical analysis of the different materials available and how they can be applied to advanced drug delivery systems. With contributions from leading experts in the field, including a foreword from distinguished scientist Nicholas Peppas, The University of Texas at Austin, USA, the book will provide both an introduction to the key areas for graduate students and new researchers in the stimuli-responsive field as well as serving as a reference for those already working on fundamental materials research or drug delivery applications.
Download or read book Smart Micro and Nanomaterials for Drug Delivery written by Ajit Behera and published by CRC Press. This book was released on 2024-08-27 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications. It has the potential to revolutionize drug therapy by making treatments more effective, reducing side effects, and improving patient outcomes. This book presents a comprehensive review of the most recent studies on smart micro- and nanomaterials with a focus on their “smart” activity for formation of targeted and responsive drug-delivery carriers. This volume: Introduces readers to the fundamentals of these the micro- and nanoscale materials as well as approaches to smart drug delivery and drug delivery systems. Covers polymers, metals, and composite materials as well as quantum dots and carbon nanotubes. Describes of all possible stimulated systems for drug delivery such as enzyme-responsive, small molecules-responsive, thermo-responsive, pH-responsive, electric field-responsive, magnetic field-responsive, light-responsive, ultrasound-responsive, and reductive environment responsive. Offers a critical perspective on the future scope of smart drug delivery systems. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.
Download or read book Getting a Handle on Smart Drug Delivery Systems A Comprehensive View of Therapeutic Targeting Strategies written by Sugapriya Dhanasekaran and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart drug delivery system (SDDS) is a recently emerging therapeutic approach, now turning into a conventional model to deliver drug to specific sites or target. Drug targeted (DT) delivery systems maintain the concentration of the drugs at desirable doses in the body and avoid the need for repeated doses. The DT delivery system have specific distinguishing features such as self-regulated, pre-programmed, multi-targeted, controlled by timely response, monitoring of the targeted drug delivery, responsive to pH, and spatially targeted. The DT delivery system exploits the biological membrane changes in the physiology of malignant cells to increase absorption or entry of drug-coated nanoparticles into targeted tissues. This system delivers a certain quantity of a therapeutic drug for longevity of its action to a targeted area within the human tissue, which in turn enhances efficacy of the treatment by reducing the side effects of drug administration. A new DT therapy strategy is a health improvement technique used in future generations for treatment of genetic diseases and intelligent drug delivery. The ultimate goal of SDDS is to administrate the drugs at the correct time with an exact dose in the body and with efficiency and specificity to the targeted cells that help the patients better adhere to their therapy regimen. The DT system enhances the maintenance of drug levels in targeted tissues and plasma without any destruction to the healthy tissues. This DT delivery system uses various strategies in targeting cells, drug delivery mechanisms, properties of targeted drug, organ-based targeted sites, disease, and drug-targeted vehicles. This chapter deals with all aspects of drug targeting and provides an overview of approaches in drug targeting, drug delivery vehicles, and strategies involved in successful delivery.
Download or read book Intelligent Nanomaterials for Drug Delivery Applications written by Nabeel Ahmad and published by Elsevier. This book was released on 2020-03-29 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intelligent Nanomaterials for Drug Delivery Applications discusses intelligent nanomaterials with a particular focus on commercial and premarket tools. The book looks at the applications of intelligent nanomaterials within the field of medicine and discusses their future role. This includes the use of intelligent nanomaterials for drugs used in cardiovascular and cancer treatments and examines the promising market of nanoparticles for biomedical and biosensing applications. This resource will be of great interest to scientists and researchers involved in multiple disciplines, including micro- and nano-engineering, bionanotechnology, biomedical engineering, and nanomedicine, as well as pharmaceutical and biomedical industries. Focuses on applications of intelligent nanomaterials within the field of medicine and discusses their role in the future Discusses intelligent nanomaterials, with a particular focus on commercial and premarket tools Examines the promising market of nanoparticles for biomedical and biosensing applications
Download or read book Study on Multifunctional Smart Drug Delivery Systems written by Yunsuk Jo and published by . This book was released on 2004 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fundamentals of Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2021-10-12 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Download or read book Nanopharmaceutical Advanced Delivery Systems written by Vivek Dave and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.
Download or read book Implantable Drug Delivery Systems written by Urban Laffer and published by S. Karger AG (Switzerland). This book was released on 1991 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advanced Materials in Drug Release and Drug Delivery Systems written by Katarzyna Winnicka and published by MDPI. This book was released on 2021-09-03 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of new drug molecules is costly and requires longitudinal, wide-ranging studies; therefore, designing advanced pharmaceutical formulations for existing and well-known drugs seems to be an attractive device for the pharmaceutical industry. Properly formulated drug delivery systems can improve pharmacological activity, efficacy and safety of the active substances. Advanced materials applied as pharmaceutical excipients in designing drug delivery systems can help solve problems concerning the required drug release—with the defined dissolution rate and at the determined site. Novel drug carriers enable more effective drug delivery, with improved safety and with fewer side effects. Investigations concerning advanced materials represent a rapidly growing research field in material/polymer science, chemical engineering and pharmaceutical technology. Exploring novel materials or modifying and combining existing ones is now a crucial trend in pharmaceutical technology. Eleven articles included in the the Special Issue “Advanced Materials in Drug Release and Drug Delivery Systems” present the most recent insights into the utilization of different materials with promising potential in drug delivery and into different formulation approaches that can be used in the design of pharmaceutical formulations.
