Download or read book Simian Hemorrhagic Fever written by Jens Kuhn and published by Springer. This book was released on 2016-01-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simian hemorrhagic fever is an acutely fatal disease of Asian macaques. It is caused by simian hemorrhagic fever virus (SHFV), which is currently classified as an arterivirus in the family Arteriviridae, order Nidovirales. In contrast to its closest relatives, the arterviruses equine arteritis virus, lactate dehydrogenase-elevating virus, and porcine respiratory and reproductive syndrome virus, SHFV is almost completely uncharacterized. Thus far, SHFV has never been isolated from wild animals, and all outbreaks have occurred within primate-holding facilities. Recently, scientific interest in simian hemorrhagic fever has increased in the biodefense community because the disease closely resembles viral hemorrhagic fevers (VHFs) caused by certain arena-, bunya-, flavi-, and filovirids. In contrast to these viruses, SHFV does not cause disease in humans, is not listed as a Select Agent or an NIAID Priority Pathogen, and can be handled in standard (A)BSL-2 laboratory environments. SHFV may therefore be a valuable tool for developing nonhuman primate models for VHF, which may not only allow for the better characterization of VHF pathogenesis and the testing of general anti-VHF pharmaceuticals, but may also be used as a training tool for new maximum-containment facilities in regards to safety testing of infrastructure and standard operation procedures. This review summarizes the scientific knowledge on SHFV and the disease it causes.”
Download or read book Structure and Morphogenesis of Simian Hemorrhagic Fever Virus written by Owen Leslie Wood and published by . This book was released on 1972 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kinetics of Simian Hemorrhagic Fever Virus Neutralization Test written by Vernol St. Clair Sealy and published by . This book was released on 1971 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Simian Hemorrhagic Fever SHF Virus Phase 2 written by Margo A. Brinton and published by . This book was released on 1992 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phase II of this contract required that we develop and screen hybridoma cell lines which produce monoclonal antibodies specific for simian hemorrhagic fever (SHFV) virus.
Download or read book Characterization of a Simian Hemorrhagic Fever Virus Large Envelope Glycoprotein Gene and Its Product written by Xiaochun Wang and published by . This book was released on 1999 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Simian Hemorrhagic Fever SHF Virus Phase 1 written by Margo A. Brinton and published by . This book was released on 1991 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous published reports on the number of SHFV structural proteins present inconclusive and conflicting data. Therefore our initial experiments were aimed at developing purification methods for obtaining SHFV as free of contaminating cell proteins as possible and at identifying the viral specific proteins in these purified virus preparations. SHFV was found to be relatively fragile and discontinuous glycerol gradient purification was found to give the best yields of intact virus. Western blot analysis and detergent treatment were then used to identify the SHFV proteins in the purified virion preparations.
Download or read book Simian Hemorrhagic Fever written by Cathy A. Johnson-Delaney and published by . This book was released on 1990 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Simian Virology written by Alexander F. Voevodin and published by John Wiley & Sons. This book was released on 2009-08-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simian Virology is the first text to comprehensively cover all currently known simian viruses. Chapters provide an overview of nonhuman primate models of medically important viral diseases as well as natural infections of nonhuman primates with human and animal viruses. The text covers a variety of topics including primate models of medically important viral diseases such as AIDS, hypotheses on the origins of epidemic forms of HIV, and viral diseases caused by non-simian viruses in both wild and captive primates.
Download or read book Characterization of the Interaction Between Cellular Proteins and the Positive stand 3 Terminal Sequence of Simian Hemorrhagic Fever Virus written by Taronna R. Maines and published by . This book was released on 2000 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Viruses and Human Disease written by Ellen G. Strauss and published by Elsevier. This book was released on 2007-09-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
Download or read book Positive Strand RNA Viruses written by Margo A. Brinton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Positive-strand RNA viruses include the majority of the plant viruses, a number of insect viruses, and animal viruses, such as coronaviruses, togaviruses, flaviviruses, poliovirus, hepatitis C, and rhinoviruses. Works from more than 50 leading laboratories represent latest research on strategies for the control of virus diseases: molecular aspects of pathogenesis and virulence; genome replication and transcription; RNA recombination; RNA-protein interactions and host-virus interactions; protein expression and virion maturation; RNA replication; virus receptors; and virus structure and assembly. Highlights include analysis of the picornavirus IRES element, evidence for long term persistence of viral RNA in host cells, acquisition of new genes from the host and other viruses via copy-choice recombination, identification of molecular targets and use of structural and molecular biological studies for development of novel antiviral agents.
Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Download or read book The Hot Zone written by Richard Preston and published by Corgi. This book was released on 1995 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagine a killer with the infectiousness of the common cold and power of the Black Death. Imagine something so deadly that it wipes out 90% of those it touches. Imagine an organism against which there is no defence. But you don't need to imagine. Such a killer exists: it is a virus and its name is Ebola. The Hot Zone tells what happens when the unthinkable becomes reality: when a deadly virus, from the rain forests of Africa, crosses continents and infects a monkey house ten miles from the White House. Ebola is that reality. It has the power to decimate the world's population. Try not to panic. It will be back. There is nothing you can do...
Download or read book Occupational Health and Safety in the Care and Use of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 2003-06-13 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.
Download or read book The Hot Zone written by Richard Preston and published by Anchor. This book was released on 2012-03-14 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling landmark account of the first emergence of the Ebola virus. Now a mini-series drama starring Julianna Margulies, Topher Grace, Liam Cunningham, James D'Arcy, and Noah Emmerich on National Geographic. A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.
Download or read book Imported Virus Infections written by Tino F. Schwarz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals both with the epidemiologic background and the specific characteristics of vector-borne and emerging viral infections which may be spread all over the world due to today’s rapid transport of infected individuals or animal vectors. Detailed description of the situation with e.g. Dengue, Japanese encephalitis, Lassa, hepatitis, HIV and filoviruses helps to plan diagnostic approaches and to develop scenarios for the handling of patients suspected of carrying high hazard viruses.
Download or read book Topics of Clinical Interest in Nonhuman Primates Update Bibliographies written by Cathy A. Johnson-Delaney and published by . This book was released on 1991 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
