Download or read book Silica Nanoparticles as Drug Delivery System for Immunomodulator GMDP written by E. V. Parfenyuk and published by Momentum Press. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the ways of making drug delivery more efficient is the use of nanosystems for targeted delivery and timed release. This title explores advanced research on nanoparticulate delivery systems for the immune modulating agent, GMDP (N-acetylglucosaminyl-N-acetylmuramyl-Lisoglutamine), an important component in cell wall structure and receptors.
Download or read book Carrier Mediated Dermal Delivery written by Andreia Ascenso and published by CRC Press. This book was released on 2017-09-01 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents new approaches for skin aging and photocarcinogenesis and topical formulations based on nanocarrier systems for skin disorders. It discusses cosmeceuticals, laser, photodynamic therapy, and melatonin-based treatments as important strategies for photoaging management. Photodynamic therapy and melatonin can be used in the photocarcinogenesis context, too. Therefore, the inclusion of this strong antioxidant in sunscreen products could be a promising approach. The book discusses topical formulations, including emulsions (conventional formulations and emulsions stabilized by solid particles), nail films, and nanocarriers used for the delivery of actives in various skin and nail diseases such as acne, psoriasis, atopic dermatitis, fungal diseases, leishmaniasis, and skin cancer. Finally, several nanocarriers are introduced, such as lipid vesicles (ranging from the first-generation conventional liposomes to the more recent deformable vesicles), liquid crystalline nanodispersions, gelatin, and solid lipid nanoparticles. Their composition, formulation, characterization, and topical applications are also discussed. Although this is a broad topic, the most important (nano)pharmaceutical formulations are presented in the book.
Download or read book Biomaterials for Precision Cancer Medicine written by Saeid Kargozar and published by Elsevier. This book was released on 2024-10-04 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book describes the various smart biomaterial-based treatments available, reviewing how they can be designed to target specific tumor types, adapt to changes in the cell microenvironment and offer smart, personalized therapy for different cancer variants, especially those which are drug-resistant. The book provides a materials-focused look at precision cancer medicine, and is thus useful to materials scientists, biomedical engineers, and biomedical scientists – including cancer and genetic specialists – with an interest in alternative cancer therapies. - Reviews the state-of-the-art in precision and translational medicine, setting the scene for the introduction of alternative biomaterial-based therapies - Covers a range of biomaterials for personalized cancer treatment, including polymer-protein conjugates, smart nanoparticles, metal compounds, and more - Addresses preclinical assessment, health risks, challenges and future perspective of precision anti-cancer biomaterials
Download or read book Drug Delivery Devices and Therapeutic Systems written by Eric Chappel and published by Academic Press. This book was released on 2020-11-07 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. - Provides essential information on the most recent drug delivery systems available - Explains current technology and its applications to drug delivery - Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers
Download or read book Advances and Challenges in Nanomedicine written by Susan Hua and published by Frontiers Media SA. This book was released on 2019-02-28 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.
Download or read book Silver Nanoparticles written by Shweta Rajawat and published by American Society of Mechanical Engineers. This book was released on 2018 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph introduces historical background of silver and narrates exhaustive literature review conducted during the research. It gives details about the existing physical, chemical and biological approaches.
Download or read book Nanocarrier Technologies written by M. Reza Mozafari and published by Springer Science & Business Media. This book was released on 2006-09-24 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies. It is the first book with this topic. It comprises a collection of scientific articles from top research people in the field and provides an up-to-date source containing recent citation and bibliography. The book is an indispensable source of information for new researchers and scientists.
Download or read book Nanoparticulates as Drug Carriers written by V. P. Torchilin and published by Imperial College Press. This book was released on 2006 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."
Download or read book Drilling and Drilling Fluids written by George V. Chilingar and published by . This book was released on 1981 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunopotentiators in Modern Vaccines written by Virgil Schijns and published by Elsevier. This book was released on 2005-12-19 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. - Contributions from leading international authorities in the field - Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system - Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
Download or read book Thermodynamics of Systems Containing Flexible Chain Polymers written by V.J. Klenin and published by Elsevier. This book was released on 1999-06-03 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the problems of the thermodynamics of systems containing flexible-chain polymers as the basis of polymer material science. The main thermodynamic quantities and concepts are introduced and discussed in the order of the objects getting more and more complicated: gases, magnets, low-molecular-weight substances and mixtures, and finally, polymers and polymer blends.All topics are considered in a common clue, using the principle of universality. The stability conditions for the one-phase state of multi-component systems are given. Phase separation is regarded as a result of loss in stability. The critical state of a system, with the one-phase state being close to the boundary of stability conditions breaking, is discussed in detail. The effects of both light scattering (elastic and dynamic) and diffusion, as directly depending on the thermodynamic parameters characterizing the one-phase state stability, are considered in detail. One of the versions of colloid scattering, namely, the turbidity spectrum method, is described as useful for the characterization of various heterogeneous structures and for the phase analysis of polymer systems. In the approximation of mean field theories and advanced field theory, formalisms expound the following divisions of the thermodynamics of binary and polynary systems with flexible-chain polymers: conformation of the polymer coil, composition fluctuations, elastic and dynamic light scattering, diffusion in the one-phase state (including the critical range), phase separation, polymer fractionation, the coil-globule transition, phase equilibrium and separation in the system network polymer + low-molecular-weight liquid, polymer blends and multiphase separation.
Download or read book Silica Nanoparticles written by Juan Vivero-Escoto and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the authors present topical research in the study of the preparation, properties and use of silica nanoparticles. Topics discussed include the reactivity of inorganic radicals and excited triplet states in colloidal silica suspensions; multifunctional mesoporous silica nanoparticles for controlled drug delivery, multimodal imaging and simultaneous imaging and drug delivery; monodisperse luminescent silica nanoparticles and their application to DNA microarray technology.
Download or read book Polarimetric Detection Characterization and Remote Sensing written by Michael I. Mishchenko and published by Springer. This book was released on 2011-05-27 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the need for accurate and non-invasive optical characterization and diagnostic techniques is rapidly increasing, it is imperative to find improved ways of extracting the additional information contained within the measured parameters of the scattered light. This is the first specialized monograph on photopolarimetry, a rapidly developing, multidisciplinary topic with numerous military, ecological remote-sensing, astrophysical, biomedical, and technological applications. The main objective is to describe and discuss techniques developed in various disciplines to acquire useful information from the polarization signal of scattered electromagnetic waves. It focuses on the state-of-the-art in polarimetric detection, characterization, and remote sensing, including military and environmental monitoring as well as terrestrial, atmospheric, and biomedical characterization. The book identifies polarimetric techniques that have been especially successful for various applications as well as the future needs of the various research communities. The monograph is intended to facilitate cross-pollination of ideas and thereby improve research efficiency and help advance the field of polarimetry into the future. The book is thoroughly interdisciplinary and contains only invited review chapters written by leading experts in the respective fields. It will be useful to science professionals, engineers, and graduate students working in a broad range of disciplines: optics, electromagnetics, atmospheric radiation and remote sensing, radar meteorology, oceanography, climate research, astrophysics, optical engineering and technology, particle characterization, and biomedical optics.
Download or read book Biomaterials for Artificial Organs written by Michael Lysaght and published by Elsevier. This book was released on 2010-12-20 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people's lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs.Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine.With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. - Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs - Discusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacements - Further biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored
Download or read book Metallofoldamers written by Galia Maayan and published by John Wiley & Sons. This book was released on 2013-01-18 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catalysts. Metallofoldamers: From Helicates to Biomimetic Architectures describes the variety of interactions between oligomers and metal species, with a focus on non-natural synthetic molecules. Topics covered include: the major classes of foldamers and their folding driving force metalloproteins and metalloenzymes helicates: self-assembly, structure and applications abiotic metallo-DNA metallo-PNA and iDNA metallopeptides interactions of biomimetic oligomers with metal ions applications of metallofoldamers
Download or read book Drug Delivery written by Monika Schäfer-Korting and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.
Download or read book Biological Interactions on Materials Surfaces written by David A. Puleo and published by Springer Science & Business Media. This book was released on 2009-06-26 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.
