Download or read book Serotonin and Anxiety written by Caio Maximino and published by Springer Science & Business Media. This book was released on 2012-05-31 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anxiety disorders have long been a research subject for scientists in different areas of inquiry, and the particular role of serotonin – the neurotransmitter which has probably most captured the imagination of laymen and academics alike – is as elusive as the clinical aspects of serotonergic medications. Why are drugs acting at certain serotonin receptors efficacious against generalized anxiety disorder, but not panic disorder? Why is the inverse true for monoamine oxidase inhibitors? These clinically relevant issues are clarified by the neurochemical, anatomical and physiological organization of the serotonergic system. In this book, the author summarizes the latest findings regarding the role of serotonin in modulating the activity of brain regions which organize behavioral patterns associated with fear, anxiety and stress. The emergent picture is one of far greater complexity than previously thought: while the serotonergic innervation of those brain regions arises from the same structure – the dorsal raphe nucleus – that structure is not homogeneous from anatomical, physiological and neurochemical points of view, nor are its projections to the cerebral aversive and behavioral inhibition systems. The diverse findings which compose this picture of complexity – whether they arise from developmental neurobiology, electrophysiology, neurochemistry, neuroendocrinology, neuropsychopharmacology or behavioral neuroscience – are integrated in this book. Advanced undergraduate, graduate students, and researchers will benefit from the information. The result sheds light on many important questions regarding the neuroanatomical, pharmacological and functional aspects of the role of serotonin in anxiety disorders, and points to future avenues of research.
Download or read book Handbook of the Behavioral Neurobiology of Serotonin written by Christian P. Muller and published by Academic Press. This book was released on 2009-12-30 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community Of great value not only for researchers and experts, but also for students and clinicians as a background reference
Download or read book Serotonergic Mechanisms in Anxiety Disorders written by Johan A. den Boer and published by . This book was released on 1988 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Social Anxiety Disorder written by National Collaborating Centre for Mental Health (Great Britain) and published by . This book was released on 2013-08-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social anxiety disorder is persistent fear of (or anxiety about) one or more social situations that is out of proportion to the actual threat posed by the situation and can be severely detrimental to quality of life. Only a minority of people with social anxiety disorder receive help. Effective treatments do exist and this book aims to increase identification and assessment to encourage more people to access interventions. Covers adults, children and young people and compares the effects of pharmacological and psychological interventions. Commissioned by the National Institute for Health and Clinical Excellence (NICE). The CD-ROM contains all of the evidence on which the recommendations are based, presented as profile tables (that analyse quality of data) and forest plots (plus, info on using/interpreting forest plots). This material is not available in print anywhere else.
Download or read book Anxiety Disorders the Role of Serotonin written by John H. Greist and published by . This book was released on 1996 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacological Treatment of Mental Disorders in Primary Health Care written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Download or read book Neurobiology of Panic Disorder written by James C. Ballenger and published by Wiley-Liss. This book was released on 1990-02-07 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading international experts emphasize that the ultimate understanding of panic disorder as a multifaceted clinical syndrome will involve multiple viewpoints and research approaches. Their contributions to Neurobiology of Panic Disorder offer such necessarily varied perspectives. Featuring vital data obtained over the last five years, this informative volume covers the neurobiological aspects of panic disorder, with an emphasis on mechanistic and preclinical studies. Contributions include a wide range of pertinent topics such as preclinical studies of brain systems involved in anxiety, familial and genetic marker studies, potential childhood antecedents of panic disorder, and animal models of anxiety. In addition, an examination of the noradrenergic system, viewpoints on the pathogenesis, pathophysiology and treatment potential of the serotonin system, and coverage of commonly used brain imaging techniques in research and clinical evaluation are included in the text.
Download or read book On the Role of Serotonin in Anxiety Disorders written by J. A. Den Boer and published by . This book was released on 1989 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Download or read book Serotonin 1A Receptors in Depression and Anxiety written by S. M. Stahl and published by . This book was released on with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Depression and Heart Disease written by Alexander Glassman and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. Patients with psychiatric problems, particularly depression, may be more susceptible to cardiovascular disorders. Depression and Heart Disease synthesizes current evidence, including some previously unpublished data, in a concise, easy-to-read format. The authors succinctly describe the epidemiology, pathogenesis (including cytokines and genetics), and risk factors of the comorbidity between depression and heart disease. The book also reviews the best pharmacological and psychotherapeutic approaches for people with this comorbidity.
Download or read book Anxiety and Serotonin written by and published by . This book was released on 1991 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Serotonergic Neurocircuitry in Mood and Anxiety Disorders written by Dan J. Stein and published by CRC Press. This book was released on 2004-08-02 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin plays an important role in mediating mood and anxiety disorders. This volume reviews neuronal circuitry relevant to a number of these conditions, such as major depression, generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder and social anxiety. This text addresses the relationship between neuronal circuitry and serotonergic agents and how those agents are effective in the treatment of these disorders. Psychiatrists, neurologists and pharmacologists will benefit from this volume.
Download or read book The Medical Basis of Psychiatry written by S. Hossein Fatemi and published by Springer. This book was released on 2016-03-17 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt: Four years have passed since the last edition (3rd) of this book was published. In the intervening years, several reviews of this book have provided highly encouraging remarks about the value of this book in transmitting information on classification and treatment of psychiatric disorders to the audience. We are proposing to revise all chapters with an eye on accuracy and ease of use, and this is an especially timely endeavor with the upcoming publication of the Diagnostic and Statistical Manual V. All the appropriate new information on biology, etiology, diagnosis and treatment of psychiatric disorders will be added to the current proposed edition. It is our goal to recruit the same authors (if possible) who contributed to the previous edition. While all chapters will be updated (see TOC), those marked by asterisks will be the most likely to undergo more revision. Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the fourth edition of this book. In this updated and expanded edition, the reader will be provided with the most contemporary information and literature supported by a close survey of the field. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry.
Download or read book Good Anxiety written by Wendy Suzuki and published by Simon and Schuster. This book was released on 2022-09-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: World-renowned neuroscientist and author of Healthy Brain, Happy Life has developed an “absolute game-changer” (Conscious Conversations podcast) for managing unwarranted anxiety and turning it into a powerful asset. We are living in the age of anxiety, a situation that often makes us feel as if we are locked into an endless cycle of stress, sleeplessness, and worry. But what if we had a way to leverage our anxiety to help us solve problems and fortify our well-being? What if, instead of seeing anxiety as a curse, we could recognize it for the unique gift that it is? As a neuroscientist, Dr. Wendy Suzuki has discovered a paradigm-shifting truth about anxiety: yes, it is uncomfortable, but it is also essential for our survival. In fact, anxiety is a key component of our ability to live optimally. Every emotion we experience has an evolutionary purpose, and anxiety is designed to draw our attention to a number of negative emotions. If we simply approach anxiety as something to avoid, get rid of, or dampen, we actually miss an opportunity to not only manage the symptoms of anxiety better but also discover ways to improve our lives. Listening to our worries from a place of curiosity, instead of fear, can actually guide us onto a path that leads to joy. “Suzuki draws on decades of neuroscience, including her own research, and leavens her learning with a little personal storytelling to create a practical, science-backed guidebook for those seeking such a transformation” (The Wall Street Journal).
Download or read book Anxiety Disorders written by Stephen M. Stahl and published by Routledge. This book was released on 2013-02-11 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Stephen M. Stahl and Bret A. Moore have created an instant classic in Anxiety Disorders: A Guide for Integrating Psychopharmacology and Psychotherapy. Anxiety Disorders is a comprehensive reference for the psychiatry and psychology student, intern, or resident, early career psychiatrist or psychologist, and the busy clinician. It distills the most important information regarding combined treatments for anxiety and presents the material in an easily accessible, understandable, and readable format. Each chapter addresses a specific type of disorder: PTSD, panic, generalized anxiety, obsessive-compulsive and other disorders, and is authored by prominent clinicians with years of experience in providing integrated, individualized treatments. With its thorough exploration of psychopharmacological treatments, psychosocial treatments, and, crucially, the integration of the two, Anxiety Disorders is a text no 21st-century clinician or student can afford to be without.
Download or read book Fluoxetine written by Graziano Pinna and published by . This book was released on 2015-04-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.
