Download or read book Serological Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book-the fourth volume of a series on Can cer Markers-is intended to provide an updated "status report" on today's use of cancer markers in the diagnosis and monitoring of can cer, with an emphasis on cancer markers detected in the serum. It has been 7 years since the publication of the last volume in this series. The 1980, 1982, and 1985 volumes covered the development of cancer markers, not only in their roles of unraveling the basic biology of can cer, but also as increasingly important players in the management of patients with cancer. During the last 7 years we have seen the applica tion of a number of markers identified by monoclonal antibodies, as well as the beginnings of the use of genetic markers defined by mo lecular probes. Measurements of oncogenes in tissues or cells prom ise many applications for the future, but as yet, these genes have not shown to be useful as serum markers of cancer. The commercial interest in serum markers for cancer, particu larly for the diagnosis and monitoring of tumor patients, is indicated in Chapter 24 by Owen, where the total worldwide market for cancer markers is projected to increase from $148 million in 1988 to $232 million in 1993. The degree of research interest in cancer markers is reflected in the fact that in 1988 a separate category for tumor mark ers was added to Index Medicus.
Download or read book Serological Tumour Markers written by J. E. Roulston and published by . This book was released on 1993 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gives an overview of the current status, potential and clinical application of one of the latest techniques in cancer screening. The authors outline the principles and practice of serological tumour markers and provide a concise context for their application.
Download or read book Histological and Serological Tumor Markers and Gene Expression and Their Clinical Usefulness in Cancers written by Dan Hellberg and published by Nova Science Publishers. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of commercially available antibodies for the detection of biological markers, tumor markers, by immunohistochemistry or serological methods in cancer are rapidly increasing. Results in different studies are often contradictory and the usefulness of single tumor markers in different cancer types is unclear. An increasing number of studies on genetic "fingerprints" are being reported. This book represents the most comprehensive and up-to-date publication on histological and serological tumor markers, also commenting recent genetic studies. Sixteen major cancer types and an additional chapter on HIV-related cancers are reviewed by more than 40 authors. These are cancer of the breast, lung, esophagus, stomach, pancreas, liver, colon, rectum, anus, skin, brain, prostate, penis, ovary, uterus, uterine cervix and HIV-related cancers. The authors are active and respected researchers, experts in their fields. Tumor markers will be evaluated for clinical usefulness in diagnostics, prognosis and therapy. Definitive present usefulness is given for the specific cancer types and their purpose of use. Tumor markers that are still being evaluated but of possible future clinical importance are discussed. The index will make it easy to find a particular tumor marker and compare studies on different cancer types. The book is meant to inspire clinical and laboratory management as well as planning research and evaluation of results. Thus, oncologists, pathologists and other physicians who are involved in patients with cancer will find it useful.
Download or read book Serological Tumor Markers for Monitoring Breast Cancer written by György Sölétormos and published by . This book was released on 2001 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Markers written by Eleftherios P. Diamandis and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2002 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in Tumor Marker Research written by Lee I. Swenson and published by Nova Publishers. This book was released on 2007 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Download or read book Human Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro duce substances that can be detected by currently available immuno chemical or biochemical methods. These "cancer markers" may be se creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence Jones protein. In a series of lectures delivered to the Royal College of Phy sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].
Download or read book A Comparative Study of Four Serological Tumor Markers for the Detection of Breast Cancer written by Shawn Russell Clinton and published by . This book was released on 2001 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Diagnostics written by Robert M. Nakamura and published by Springer Science & Business Media. This book was released on 2004-07-16 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews recent and emerging clinical laboratory tests that can help in the early detection, evaluation, and prediction of human tumors. Emphasizing the importance of molecular and genetic RNA/DNA tets that detect persons at high risk for specific cancers, the authors explore these novel serological assays, cellular assays useful for anatomic pathology, and molecular and genetic assays.
Download or read book Biomarkers in Cancer written by Victor R. Preedy and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comparison of Six Serological Tumor Markers CEA CA 15 3 CA 27 29 CA 549 NSE and Ferritin for the Detection of Breast Cancer written by Sharae Johnson and published by . This book was released on 2005 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Marker Protocols written by Margaret Hanausek and published by Humana Press. This book was released on 2010-10-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of cancer is a slow process and it very often takes a number of years before a tumor becomes clinically evident. No current te- nique is sensitive and specific enough to detect tumors at their earliest stage, i. e. , when the tumor is smaller than one billion cells. Consequently, the d- ease is usually diagnosed in an advanced state, very often when it is already beyond the reach of therapeutic strategies. This is the main stumbling block to the secondary prevention that would reduce cancer mortality. There is hope, however, because in the last decade we have witnessed an explosion of reports dealing with tumor markers. In many instances, simple, noninvasive diagnostic tests are becoming available to detect the early signs ofneoplasia. Interest in early detection of neoplasia is growing among those basic scientists, cli- cians, and health professionals who realize that progress in reducing cancer mortality is dependent to a great degree on its early detection and prevention. Some disappointment usually accompanies these discoveries, because what at first glance proves to be promising, is in many instances, applicable only to a limited number of cases. What is the cause of these failures? The answer may be that cancer is a multitude of neoplastic diseases in which endogenous and exogenous etiologic factors contribute either sim- taneously or over a lifetime to the development of disease.
Download or read book Cellular Cancer Markers written by Carleton T. Garrett and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Cellular Cancer Markers leading pathologists and physicians review today's most promising cellular cancer markers, an important emerging class of prognostic markers that can be used in the clinical evaluation of cancer patients. The markers reviewed have been chosen because they are biologically relevant to the growth of cells and possess an accurate and reproducible assay for detection. They also are predictors of tumor behavior, are useful in making clinical decisions, and are cost effective. Cellular Cancer Markers provides a status report for markers of tumor cell activation, proliferation, and longevity that makes possible an informed judgment regarding the value of many newly proposed tumor markers. It also offers insight into the latest approaches to diagnosing cancer and an appreciation of how these marker-based tests can clarify the prognosis of cancer.
Download or read book Tumor Markers Research Focus written by Deborah Chang and published by Nova Publishers. This book was released on 2007 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Download or read book A Comparison of Four Serological Tumor Markers CEA AFP CA 27 29 and CA 15 3 for the Detection of Stomach Cancer written by Kevin Lee Beason and published by . This book was released on 2001 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Markers written by Saad Eissa and published by Hodder Education. This book was released on 1998 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive introduction to the expression of tumor markers in association with various neoplasms, the methods used in their detection and their clinical relevance to the diagnosis and treatment of cancer. It will be an invaluable guide for clinicians, pathologists and research workers requiring an in-depth introduction to this subject and, with sections devoted to the exploitation of new techniques in immunohistochemistry, flow cytomtry, cancer genetics and molecular biology for the identification of tumor markers, can also be used as a laboratory reference.
Download or read book Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental cancer products (oncodevelopmental markers, ODM) not only serve as diagnostic and prognostic indicators but also may be used to study the nature of the carcinogenic process and the biology of tumors. For many years oncologists have searched for markers of cancer cells that would permit unequivocal recognition of cancer in contrast to noncancerous tissue. The earliest and still most widely used method of identification of cancer tissue or cells is the structural resemblance of cancer tissue to fetal or immature tissue. Pathologists not only recognize cancer by its morphologic similarity to fetal tissues, but also in many instances can relate the behavior of a given tumor to the degree of tissue differentiation. Thus, poorly differentiated tumors that resemble fetal tissue generally grow more rapidly and metastasize earlier than do well-differentiated tumors that more closely resemble adult tissue. In recent years the commonality of fetal and cancer tissue has been extended to products of tumor cells that, can be analyzed by biochemical, immunological, or physiological techniques. Increas ingly, products of cancer cells similar to fetal products are being identified and studied. These products range from cell-surface markers (fetal or differentiation antigens), placental proteins, hormones, and isoenzymes to a multitude of products, such as carcinoembryonic antigen (CEA), alphafetoprotein (AFP), lymphocyte markers, and nucleic acids, such as tRNA, that are produced in small amounts by v vi PREFACE continually differentiating cells in the adult but in much greater amounts by tumors.
