Download or read book Sensory and Metabolic Control of Energy Balance written by Wolfgang Meyerhof and published by Springer Science & Business Media. This book was released on 2010-09-24 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, the prevalence of obesity has dramatically increased in western and westernized societies. Its devastating health consequences include hypertension, cardiovascular diseases, or diabetes and make obesity the second leading cause of unnecessary deaths in the USA. As a consequence, obesity has a strong negative impact on the public health care systems. Recently emerging scienti?c insight has helped understanding obesity as a complex chronic disease with multiple causes. A multileveled gene–environment interaction appears to involve a substantial number of susceptibility genes, as well as associations with low physical activity levels and intake of high-calorie, low-cost, foods. Unfor- nately, therapeutic options to prevent or cure this disease are extremely limited, posing an extraordinary challenge for today’s biomedical research community. Obesity results from imbalanced energy metabolism leading to lipid storage. Only detailed understanding of the multiple molecular underpinnings of energy metabolism can provide the basis for future therapeutic options. Numerous aspects of obesity are currently studied, including the essential role of neural and endocrine control circuits, adaptive responses of catabolic and anabolic pathways, metabolic fuel sensors, regulation of appetite and satiation, sensory information processing, transcriptional control of metabolic processes, and the endocrine role of adipose tissue. These studies are predominantly fuelled by basic research on mammalian models or clinical studies, but these ?ndings were paralleled by important insights, which have emerged from studying invertebrate models.
Download or read book Sensory and Metabolic Control of Energy Balance written by Wolfgang Meyerhof and published by Springer. This book was released on 2010-11-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, the prevalence of obesity has dramatically increased in western and westernized societies. Its devastating health consequences include hypertension, cardiovascular diseases, or diabetes and make obesity the second leading cause of unnecessary deaths in the USA. As a consequence, obesity has a strong negative impact on the public health care systems. Recently emerging scienti?c insight has helped understanding obesity as a complex chronic disease with multiple causes. A multileveled gene–environment interaction appears to involve a substantial number of susceptibility genes, as well as associations with low physical activity levels and intake of high-calorie, low-cost, foods. Unfor- nately, therapeutic options to prevent or cure this disease are extremely limited, posing an extraordinary challenge for today’s biomedical research community. Obesity results from imbalanced energy metabolism leading to lipid storage. Only detailed understanding of the multiple molecular underpinnings of energy metabolism can provide the basis for future therapeutic options. Numerous aspects of obesity are currently studied, including the essential role of neural and endocrine control circuits, adaptive responses of catabolic and anabolic pathways, metabolic fuel sensors, regulation of appetite and satiation, sensory information processing, transcriptional control of metabolic processes, and the endocrine role of adipose tissue. These studies are predominantly fuelled by basic research on mammalian models or clinical studies, but these ?ndings were paralleled by important insights, which have emerged from studying invertebrate models.
Download or read book Endocrinology of the Gut written by Frank P. Brooks and published by . This book was released on 1974 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neural and Metabolic Control of Macronutrient Intake written by Hans-Rudolf Berthoud and published by CRC Press. This book was released on 1999-10-25 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: When an excessive proportion of the human energy requirement is derived from fat, the likelihood of obesity increases. Any such individual is at risk for diabetes and cardiovascular disease- grave and costly health hazards. The selective control of fat ingestion is a promising solution to these concerns. Existing data suggests that macronutrient intake can be manipulated. Further research is working to create pharmacological tools that will suppress fat consumption. It will also be possible to fight obesity, heart disease and diabetes. Neural and Metabolic Control of Macronutrient Intake systematically discusses the known physiological mechanisms involved in macronutrientselection, including their molecular, genetic and neurochemical aspects. The book is also a critical review of the hypothesis that ingestion of the three nutrients is regulated by separate neural control mechanisms, leaving open the possibility that strategies could be devised to intervene in bodily control systems and alter the proportion of fat in the diet. This reference provides three types of information: First, the basic background of the biochemical and physiological systems as they relate to macronutrient selection. Second, opinions and data concerning to what degree animals and humans show evidence of macronutrient selection. And, third, evidence about how the central nervous system might be involved in the choices animals make among macronutrients.
Download or read book Metabolic Regulation of Energy Balance by Body Fat in Humans written by Arnold Shupikai Rinomhota and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fasting Taste Perception and Metabolic Regulation written by Wenjing Li and published by LAP Lambert Academic Publishing. This book was released on 2013-01 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taste perception, via reception of tastants and endocrine signalling within the tongue, plays a key role in consumer acceptance and sensory evaluation of foods. Taste perception triggers hormones that are crucial in the control energy balance and appetite exerts a strong effect on food intake, satiety and metabolic regulation. Due to the complex interaction of genetic, biological and psychological factors, the influence of fasting on the relationship between taste perception and associated metabolic parameters remains to be explored. This book, therefore investigates the effect of fasting on interaction between taste perception and metabolic regulation through three main objectives. The first objective is to explore the relationship between the bitter taste sensitivity and the fatty acid taste sensitivity. The second objective is to investigate the effect of overnight fasting or meal consumption on sweet and fatty acid taste perception. This led to a further investigation on the last objective- the role of key plasma metabolites on fatty acid taste perception in fasting and satiated states.
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolism at a Glance written by J. G. Salway and published by John Wiley & Sons. This book was released on 2017-02-06 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism at a Glance presents a concise, illustrated summary of metabolism in health and disease. This essential text is progressively appropriate for introductory through to advanced medical and biochemistry courses. It also provides a succinct review of inborn errors of metabolism, and reference for postgraduate medical practitioners and biomedical scientists who need a resource to quickly refresh their knowledge. Fully updated and extensively illustrated, this new edition of Metabolism at a Glance is now in full colour throughout, and includes new coverage of sports biochemistry; the metabolism of lipids, carbohydrates and cholesterol; glyceroneogenesis, α-oxidation and ω-oxidation of fatty acids. It also features the overlooked “Krebs Uric Acid Cycle”. Metabolism at a Glance offers an accessible introduction to metabolism, and is ideal as a revision aid for students preparing for undergraduate and USMLE Step 1 exams.
Download or read book Nutrition and Aging written by Irwin H. Rosenberg and published by Karger Medical and Scientific Publishers. This book was released on 2002 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humanity is aging. In the last century, life expectancy has increased by as much as 25 years, the greatest increase in 5'000 years of history. As a consequence the elderly constitute today the fastest growing segment of the world's population. This new situation creates many social problems and challenges to health care which both the developed as well as the developing countries will have to cope with. The present publication shows that scientific progress has reached a level where nutritional interventions may play a decisive part in the prevention of degenerative conditions of age, improvement of quality of life and impact on health care burden and resources. Topics deal with such different aspects as the influence of prenatal and early infant nutrition on the future aged individual and effects of energetic restriction on longevity. Further contributions include studies on mitochondrial alterations, digestive problems, specific metabolic deviations mediated by insulin, bone degradation, structural changes, neuromuscular dysfunctions, mental state of the elderly as well as the response of the immune system to nutrient intake. Finally the book offers a review of requirements appropriate to meet the age-related public health challenges of the 21st century.
Download or read book Hormones Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Download or read book Obesity and Diabetes Mellitus written by E. I. Sokolov and published by VSP. This book was released on 1997-04 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient.
Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Download or read book Fat Detection written by Jean-Pierre Montmayeur and published by CRC Press. This book was released on 2009-09-14 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se
Download or read book Bariatric Endocrinology written by J. Michael Gonzalez-Campoy and published by Springer. This book was released on 2018-10-26 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book – the first ever on bariatric endocrinology – is a comprehensive endocrine and metabolism approach to the diseases that result from excess fat mass accumulation and adipose tissue dysfunction. It takes an approach that places adipose tissue at the center of the clinical approach to patients, as opposed to the complications of adipose tissue accumulation and dysfunction, which has been the dominant approach to date. Initial chapters include discussion of adipose tissue physiology and pathophysiology (adiposopathy), hormonal, central nervous system, and gut microbiome regulation of energy balance and stores, and primary and secondary causes of adipose tissue weight gain. Subsequent chapters cover the evaluation and treatment of dyslipidemia, insulin resistance and hyperglycemic states, hypertension, neoplasia, and gonadal function in men and women. Management strategies, such as nutrition, physical activity, pharmacotherapy, and bariatric procedures, round out the presentation. Each chapter is bookended by bullet-pointed clinical pearls at the beginning and a full reading list at the end. Written and edited by experts in the field of endocrinology and obesity management, Bariatric Endocrinology redefines practice to focus not just on weight loss as measured in pounds lost, but on adipose tissue mass and pathology, decreasing fat mass for adiposity-related diseases and returning adipose tissue to normal function.
Download or read book Anatomy Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text
Download or read book Appetite and Food Intake written by Ruth Harris and published by CRC Press. This book was released on 2008-02-21 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complex interplay of social, economic, psychological, nutritional and physiological forces influence ingestive behavior and demand an integrated research approach to advance understanding of healthful food choices and those that contribute to health disordersincluding obesity-related chronic diseases. Taking a multifaceted approach, Appe
Download or read book Gut Hormones written by Stephen Robert Bloom and published by . This book was released on 1981 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
