Download or read book Selected Organic Syntheses written by Ian Fleming and published by John Wiley & Sons. This book was released on 1973 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Synthesis 1; 2. Synthesis in the nineteenth century 7; 3. Tropinone and cocaine 17; 4. Cyclooctatetraene 24; 5. Callistephin chloride 26; 6. Thyroxine 30; 7. Ascorbic acid 34; 8. Mesoporhyrin-IX and haemin 40; 9. Morphine 50; 10. Cholesterol and cortisone 57; 11. Cycloartenol 66; 12. ß-Carotene 70; 13. Dehydroabietic acid 75; 14. The penicillins 80; 15. Cephalosporin C 85; 16. Coenzyme A 92; 17. Peptide synthesis: bradykinin 98; 18. Chlorophyll-a 112; 19. Patchouli alcohol 125; 20. A steroid synthesis or an industrial scale 130; 21. Caryophyllene 137; 22. [18]Annulene 141; 23. Cyclobutadiene 144; 24. Adamantanes 149; 25. Cyclopropanones 153; 26. A third steroid synthesis 156; 27. Cecropia juvenile hormone 165; 28. A second synthesis of the cecropia juvenile hormone 171; 29. Lycopodine 176; 30. Colchicine (first synthesis) 183; 31. Colchicine (second synthesis) 193; 32. Colchicine (third synthesis) 198; 33. Colchicine (fourth synthesis) 202; 34 prostaglandins F2[alpha] and E2 208; 35. reserpine 214.
Download or read book Organic Synthesis Via Examination Of Selected Natural Products written by David J Hart and published by World Scientific. This book was released on 2011-02-21 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products.The book provides readers with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to the present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided.
Download or read book Designing Organic Syntheses written by Stuart Warren and published by John Wiley & Sons. This book was released on 1991-01-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaches students to use the language of sythesis directly (utilizing the grammar of synthon and disconnection) rather than translating it into that of organic chemistry.
Download or read book Organic Synthesis written by Paul Wyatt and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
Download or read book Solid Phase Organic Syntheses Volume 1 written by Anthony W. Czarnik and published by John Wiley & Sons. This book was released on 2004-04-07 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid expansion of combinatorial chemistry has renewed interest in solid-phase organic synthesis, a method that lends itself well to creating and screening large numbers of lead compounds. Solid-Phase Organic Syntheses, Volume 1 is the first volume in a series that will be updated annually, filling a gap in the existing chemical literature. Providing information previously unavailable from a single resource, this series is dedicated to providing researchers in the field with validated and tested methods for the solid-phase synthesis of interesting and biologically relevant molecules. Solid-phase methods will virtually always be invented for application in combinatorial organic synthesis. To meet these specific needs, Solid-Phase Organic Syntheses, Volume 1 focuses on a single type of synthetic transformation accomplished on solid support, and indicates how procedures are optimized to work with a structurally-wide variety of reagents. Written by recognized leaders in the field who review and test all chemical protocols before publication, organic transformations are organized by type of compound synthesized and reaction type. For the first time, experimental details for proven solid-phase synthetic molecules are collected in a single, invaluable resource. Solid-Phase Organic Syntheses, Volume 1 provides combinatorial chemists and researchers in organic chemistry and medicinal chemistry with the tools and descriptive protocols to achieve syntheses of desired compounds using a variety of solid supports and reagents.
Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples* An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools* Extensive index quickly locates information using words found in text and drawings
Download or read book Organic Synthesis written by Michael Smith and published by Academic Press. This book was released on 2011-07-12 with total page 1536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.
Download or read book Selectivity in Organic Synthesis written by Robert S. Ward and published by John Wiley & Sons. This book was released on 1999-05-04 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selectivity is an increasingly important part of organic synthesis. The whole basis of organic chemistry, and especially organic synthesis, depends upon the selectivity which can be achieved in organic reactions. This concise textbook describes the strategies which can be adopted to improve selectivity, and the reactions which have been specially designed to afford high selectivity. The aim is to illustrate the range of processes to which these principles can be applied and the high degree of selectivity which can be achieved. Selectivity in Organic Synthesis aims to provide a solid introduction to this subject, focusing on the key areas and applications.
Download or read book Organic Synthesis written by Michael Smith and published by Academic Press. This book was released on 2016-11-22 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors
Download or read book Introduction to Strategies for Organic Synthesis written by Laurie S. Starkey and published by John Wiley & Sons. This book was released on 2012-01-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
Download or read book Organic Syntheses Based on Name Reactions and Unnamed Reactions written by Alfred Hassner and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.
Download or read book The Algebra of Organic Synthesis written by John Andraos and published by CRC Press. This book was released on 2016-04-19 with total page 1221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Algebra of Organic Synthesis combines the aims, philosophies, and efforts involved in organic synthesis, reaction optimization, and green chemistry with techniques for determining quantitatively just how "green" synthesis plans are. It provides the first complete quantitative description of synthesis strategy analysis in the context of green ch
Download or read book Organic Syntheses Based on Name Reactions written by Alfred Hassner and published by Elsevier. This book was released on 2012-01-05 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Organic syntheses based on name reactions and unnamed reactions. 1st ed. 1994.
Download or read book Organic Synthesis written by W A Smit and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.
Download or read book Practical Synthetic Organic Chemistry written by Stéphane Caron and published by John Wiley & Sons. This book was released on 2020-02-06 with total page 1560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diese Publikation ist ein Praktikerbuch für Organiker. Der Schwerpunkt liegt auf den Reaktionen, die am verlässlichsten und nützlichsten sind. Die Autoren der einzelnen Kapitel stellen Chemiker die Informationen zur Verfügung, die für die strategische Planung einer Synthese und Wiederholung der Verfahren im Labor notwendig sind. - Fasst alle wesentlichen Entwicklungen und Konzepte in einer Publikation zusammen und deckt die meisten der wichtigen Reaktionen in der organischen Chemie ab, u. a. Substitutions-, Additions-, Eliminierungsreaktionen, Umlagerung, Oxidation, Reduktion. - Behandelt die wichtigsten Reaktionen ausführlicher und zeigt die grundlegenden Prinzipien, Vor- und Nachteile der Methoden, Mechanismen und Techniken, um Reaktionen im Labor erfolgreich durchzuführen. - Mit neuen Inhalten zu den jüngsten Fortschritten in den Bereichen CH-Aktivierung, Photoredox-Katalyse und Elektrochemie, kontinuierliche chemische Prozesse und Anwendung der Biokatalyse in der Synthese. - Bietet überarbeitete Kapitel mit neuen und zusätzlichen chemischen Beispielen aus der Praxis.
Download or read book Enzyme Based Organic Synthesis written by Cheanyeh Cheng and published by John Wiley & Sons. This book was released on 2022-02-03 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme-Based Organic Synthesis An insightful exploration of an increasingly popular technique in organic chemistry In Enzyme-Based Organic Synthesis, expert chemist Dr. Cheanyeh Cheng delivers a comprehensive discussion of the principles, methods, and applications of enzymatic and microbial processes for organic synthesis. The book thoroughly explores this growing area of green synthetic organic chemistry, both in the context of academic research and industrial practice. The distinguished author provides a single point of access for enzymatic methods applicable to organic synthesis and focuses on enzyme catalyzed organic synthesis with six different classes of enzyme. This book serves as a link between enzymology and biocatalysis and serves as an invaluable reference for the growing number of organic chemists using biocatalysis. Enzyme-Based Organic Synthesis provides readers with multiple examples of practical applications of the main enzyme classes relevant to the pharmaceutical, medical, food, cosmetics, fragrance, and health care industries. Readers will also find: A thorough introduction to foundational topics, including the discovery and nature of enzymes, enzyme structure, catalytic function, molecular recognition, enzyme specificity, and enzyme classes Practical discussions of organic synthesis with oxidoreductases, including oxidation reactions and reduction reactions Comprehensive explorations of organic synthesis with transferases, including transamination with aminotransferases and phosphorylation with kinases In-depth examinations of organic synthesis with hydrolases, including the hydrolysis of the ester bond Perfect for organic synthetic chemists, chemical and biochemical engineers, biotechnologists, process chemists, and enzymologists, Enzyme-Based Organic Synthesis is also an indispensable resource for practitioners in the pharmaceutical, food, cosmetics, and fragrance industries that regularly apply this type of synthesis.
Download or read book Advances in Organic Synthesis Volume 15 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-10-29 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. Contents of this volume include: - Metal-Free and Acid-Free Activation of Carbonyl Moiety Using Molecular Halogens or N-Halamines - Anti-algal Study on Polymeric Coating Containing Metal-Metal Oxide Core-shell Nanoparticles - Functionalized Catalyst for Efficient Nucleophilic and Electrophilic Fluorination - Synthesis and Applications of Small Fluorescent Molecules - Recent Achievements in the Synthesis of Aromatic Five-Membered Heterocycles Containing One Heteroatom - Basic Ionic Liquid Catalyzed Cycloaddition Reactions for the Synthesis of 1, 2, 3-Triazoles
