Download or read book Bitumens and Bitumen Emissions and Some N and S heterocyclic Polycyclic Aromatic Hydrocarbons written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2013 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of bitumens and their emissions, the N-heterocyclic polycyclic aromatic hydrocarbons benz[a]acridine, benz[c]acridine, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[c,h]acridine, carbazole and 7H-dibenzo[c,g]carbazole, as well as the S-hetrocyclic polycyclic aromatic hydrocarbons benzo[b]naphtho[2,1-d]thiophene and dibenzothiophene. Bitumens are produced by distillation of crude oil during petroleum refining, and also occur naturally. Bitumens can be divided into six broad classes, according to their physical properties and specifications required for different applications. The major use (about 80%) of bitumens is for road paving; other uses include roofing, waterproofing, sealing and painting. The term "bitumen" should not be confused with "asphalt", which refers to the mixture of bitumen (4-10% by weight), small stones, sand and filler used for road paving. Bitumens are complex mixtures that contain a large number of organic chemical compounds. Application of bitumens may generate emissions (fumes and vapours) that may contain, among volatile and non-volatile compounds, a number of known or probable carcinogens. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of various occupations that entail exposure to bitumens and bitumen emissions, including road paving, roofing, and application of mastic asphalt, and to various heterocyclic polycyclic aromatic compounds.

Download or read book Handbook of Polycyclic Aromatic Hydrocarbons written by Bjorseth and published by CRC Press. This book was released on 1985-12-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume concerns sources of polycyclic aromatic hydrocarbons (PAH), their emission factors, and relative importance. It deals with exposure, uptake, metabolism, and detection of PAH in the human body. The volume contains an update of information in environmental and biochemical studies of PAH.

Download or read book Toxicological Profile for Polycyclic Aromatic Hydrocarbons written by and published by . This book was released on 1995 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Selected Non heterocyclic Polycyclic Aromatic Hydrocarbons written by R. F. Hertel and published by . This book was released on 1998 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Polynuclear Aromatic Compounds written by Lawrence B. Ebert and published by . This book was released on 1988 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents accounts of current research in polynuclear aromatic compounds, showing examples of studies both of pure compounds and of complex, fossil fuel related mixtures. Offers a thorough knowledge of aromatic chemistry through coverage of reduction, oxidation, and thermal reactions--including applications developed for both coal and petroleum materials. Featured topics include quantum chemical structure-reactivity relationships, spatial configurations of large polynuclear hydrocarbons, cyclophanes, and desulfurization of heterocycles. Scientists studying all aspects of the chemistry of polynuclear aromatics will discover important, pertinent information in this volume.

Download or read book PAHs written by Peter E. T. Douben and published by John Wiley & Sons. This book was released on 2003-07-25 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polycyclic aromatic hydrocarbons (PAHs), or polyarenes, are one of the largest and most structurally diverse class of organic molecules known. High percentages of polyarenes, representing a wide range of molecular sizes and structural types, are present in coal tars and petroleum residues. The major sources of PAHs are crude oil, coal and oil shale. The fuels produced from these fossil sources constitute the primary source of energy for the industrial nations of the world, and the petrochemicals from these raw materials are the basis of the synthetic fibre and plastics industries. PAHs are however, widespread pollutants and their impact on the environment and human health must be monitored and controlled. This book will review and assess our scientific understanding of the ecological exposure and effects PAHs have in different environments and habitats. It will accomplish this by taking the recipients of the pollution in the environment as starting points and working its way back through pathways to access what is required for our understanding of effects and rationale for control. Although this book will concentrate on ecological exposure of PAHs, the general impacts of PAHs on human populations will be touched upon. It is thought to be the first book to focus on the ecological aspects of PAHs.

Download or read book Toxicology and Risk Assessment written by Helmut Greim and published by John Wiley & Sons. This book was released on 2018-08-10 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

Download or read book Safety Evaluation of Certain Contaminants in Food written by Joint FAO/WHO Expert Committee on Food Additives. Meeting and published by Food & Agriculture Org.. This book was released on 2006 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons written by Andreas Luch and published by World Scientific. This book was released on 2005-08-22 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview on the molecular mode of action of carcinogenic polycyclic aromatic hydrocarbons (PAHs). PAHs are by-products arising from incomplete combustion of organic matter that are frequently released into our environment, and thus are ubiquitously detectable. Many PAHs are strong carcinogens in rodent bioassays and have been linked to increased incidences of various types of cancer in humans. The present book covers all aspects of PAH-induced carcinogenesis; it is a collection of articles written by some of the most recognizable PAH researchers, reviewing the present knowledge in this field. The topics include: exposure to and biomonitoring of PAHs in the human population; metabolic activation of PAHs; genotoxicity and repair of PAH-induced DNA damage; and factors modulating individual susceptibility to the deleterious effects of PAHs. Contents:Polycyclic Aromatic Hydrocarbon-Induced Carcinogenesis — An Introduction (A Luch)Metabolic Activation and Detoxification of Polycyclic Aromatic Hydrocarbons (A Luch & W M Baird)Biomonitoring of Polycyclic Aromatic Hydrocarbons — Human Exposure (A Seidel)Macromolecular Adducts as Biomarkers of Human Exposure to Polycyclic Aromatic Hydrocarbons (D H Phillips)DNA Damage and Mutagenesis Induced by Polycyclic Aromatic Hydrocarbons (A Besaratinia & G P Pfeifer)Mechanisms of Repair of Polycyclic Aromatic Hydrocarbon-Induced DNA Damage (H Naegeli & N E Geacintov)Aberrant Gene Expression and Cell Signalling/Epigenetic Effects Induced by Polycyclic Aromatic Hydrocarbons (P Steinberg)Indicator Assays for Polycyclic Aromatic Hydrocarbon-Induced Genotoxicity (H Glatt)Tumorigenicity of Polycyclic Aromatic Hydrocarbons (S Amin & K El-Bayoumy)Genetic Susceptibility to Polycyclic Aromatic Hydrocarbon-Induced Carcinogenesis (A Hirvonen)Polycyclic Aromatic Hydrocarbon-Induced Carcinogenesis — An Integrated View (A Luch) Readership: Graduate students, academics and researchers in toxicology, biochemistry, oncology and the life sciences. Keywords:PAH;Polycyclic Aromatic Hydrocarbon;Carcinogenesis;Genotoxicity

Download or read book Process Induced Food Toxicants written by Richard H. Stadler and published by John Wiley & Sons. This book was released on 2008-12-09 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Process-Induced Food Toxicants combines the analytical, health, and risk management issues relating to all of the currently known processing-induced toxins that may be present in common foods. It considers the different processing methods used in the manufacture of foods, including thermal treatment, drying, fermentation, preservation, fat processing, and high hydrostatic pressure processing, and the potential contaminants for each method. The book discusses the analysis, formation, mitigation, health risks, and risk management of each hazardous compound. Also discussed are new technologies and the impact of processing on nutrients and allergens.

Download or read book Quantum Nanochemistry Volume Five written by Mihai V. Putz and published by CRC Press. This book was released on 2016-04-27 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 5 of the 5-volume Quantum Nanochemistry focuses on modeling and predicting of the enzyme kinetics and quantitative structure-activity relationships. It reveals the quantum implications to bio-organic and bio-inorganic systems, to enzyme kinetics, and to pharmacophore binding sites of chemical-biological interaction of molecules through cell membranes in targeting specific bindings modeled by celebrated QSARs (Quantitative Structure-Activity Relationships) here reshaped as Qu-SAR (Quantum Structure-Activity Relationships).

Download or read book Advances in Molecular Toxicology written by and published by Academic Press. This book was released on 2016-11-11 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events are also reviewed by leading experts in the field. Provides cutting-edge reviews by leading workers in the discipline Includes in-depth dissection of the molecular aspects that are of interest to a broad range of scientists, physicians, and any student in the allied disciplines Presents leading-edge applications of technological innovations in chemistry, biochemistry, and molecular medicine

Download or read book Bentonite Kaolin and Selected Clay Minerals written by Zoltán Adamis and published by World Health Organization. This book was released on 2005-05-03 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published under the joint sponsorship of the UNEP, the ILO and the WHO and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals. 'IPCS International Programme on Chemical Safety'

Download or read book Biomarkers and Human Biomonitoring written by Lisbeth Knudsen and published by Royal Society of Chemistry. This book was released on 2011-10-19 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern from exposure to endocrine disruptors and the genotoxic compound. Biomarkers of specific exposures to a wide range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, PAHs, dioxins, mercury and arsenic are also discussed. Volume two decribes human biomonitoing of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as effect biomarkers of hemoglobin adducts, germ cells, micronuclei and individual susceptability. The books will be essential reading for toxicologists, environmental scientists and all those working in the safety and risk assessment of chemicals.

Download or read book Biochemical Toxicology written by Muharrem Ince and published by BoD – Books on Demand. This book was released on 2020-07-29 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.

Download or read book Global Contamination Trends of Persistent Organic Chemicals written by Bommanna G. Loganathan and published by CRC Press. This book was released on 2011-08-09 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental pollution by man-made persistent organic chemicals (POCs) has been a serious global issue for over half a century. POCs are prevalent in air, water, soil, and organisms including wildlife and humans throughout the world. They do not degrade and cause long-term effect in organisms. Exposure to certain POCs may result in serious environ

Download or read book Persistent Organic Pollutants and Toxic Metals in Foods written by Martin Rose and published by Elsevier. This book was released on 2013-05-15 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public. They persist in the environment, accumulate in food chains and may adversely affect human health if ingested over certain levels or with prolonged exposure. Persistent organic pollutants and toxic metals in foods explores the scientific and regulatory challenges of ensuring that our food is safe to eat. Part one provides an overview of regulatory efforts to screen, monitor and control persistent organic pollutants and heavy metals in foods and includes case studies detailing regulatory responses to food contamination incidents. Part two moves on to highlight particular POPs, toxic metals and metalloids in foods, including dioxins and polychlorinated biphenyls (PCBs), mercury, polycyclic aromatic hydrocarbons (PAHs) and phthalates. Persistent organic pollutants and toxic metals in foods is a standard reference for those in the food industry responsible for food safety, laboratories testing for food chemical safety, regulatory authorities responsible for ensuring the safety of food, and researchers in industry and academia interested in the science supporting food chemical safety. Includes case studies which detail regulatory responses to food contamination incidents Considers the uptake and transfer of persistent organic pollutants in the food chain and the risk assessment of contaminates in food Details perticular persistent organic pollutants, toxic metals and metalloids in foods including polychlorinated biphenyls (PCBs), per- and polyfluoroalkyl substances (PFASs), mercury and arsenic among others