Download or read book Secondary Metabolites and Biotherapeutics written by Awanish Kumar and published by Elsevier. This book was released on 2024-03-18 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary Metabolites and Biotherapeutics presents the latest biotechnological advancements in the production of target secondary metabolites for medicinal use, including topics such as transcriptomics, nanotechnology, gene editing tools like CRISPR/CAS, secondary metabolites source and production.? Secondary metabolites derived from plants as a response to stress have always played a vital role in the pharmaceutical industry to produce medicines. However, their limited production in plants have always raised concerns for large-scale production. With the advancement of modern biotechnology, researchers around the globe are now able to engineer plants with specific chemical compositions. This book is a valuable resource to researchers in biotechnology, medical sciences, pharmaceutical biotechnology, pharmacology and plant biology. Provides updates in the field of secondary metabolite used in therapy? Covers the latest biotechnological advancements in the production of target secondary metabolites for the purpose of medicinal use? Elucidates the medicinal value of the plants used traditionally by different ethnic groups for treating various disorders? Presents the medicinal value of endophytes

Download or read book Secondary Metabolites written by Ramasamy Vijayakumar and published by BoD – Books on Demand. This book was released on 2018-09-05 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.

Download or read book Secondary Metabolite Biosynthesis and Metabolism written by Richard J. Petroski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was developed from the proceedings of the American Chemical Society, Division of Agricultural & Food Chemistry, subdivision of Natural Products Symposium "Biosynthesis and Metabolism of Secondary Natural Products" held in Atlanta, Georgia, April 1991. The objective of the conference was to bring together people from apparently diverse fields, ranging from biotechnology, metabolism, mechanistic organic chemistry, enzymology, fermentation, and biosynthesis, but who share a common interest in either the biosynthesis or the metabolism of natural products. It is our intention to help bridge the gap between the fields of mechanistic bio-organic chemistry and biotechnology. Our thanks go to Dr. Henry Yokoyama, co-organizer of the symposium, the authors who so kindly contributed chapters, the conference participants, and to those who assisted in the peer review process. We also thank the financial supporters of the symposium: ACS/AGFD, NIH General Medical Sciences, and the agricultural, pharmaceutical, biotechnology, and chromatography companies. A full list of the supporting corporations and institutions is given on the following page. Pharma-Tech and P.C., Inc. are manufacturers of instrumentation for high-speed countercurrent chromatography. We thank the Agricultural Research Service and the U. S. Department of Agriculture for granting me permission to co-organize the conference and for us to complete the book. Richard J. Petroski Susan P. McCormick USDA, ARS, National Center for Agricultural Utilization Research Peoria, IL 61604 June 10, 1992 vii CONTENTS ANTIBIOTICS Polyketide Synthetases: Enzyme Complexes and Multifunctional Proteins Directing the Biosynthesis of Bacterial Metabolites from Fatty Acids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 . . . . . . . . . . .

Download or read book Plant Secondary Metabolites written by Anil Kumar Sharma and published by Springer Nature. This book was released on 2022-03-02 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant secondary metabolites are plant-based natural products that display a variety of pharmacological effects. This book discusses the invaluable bioactivity and multifaceted potential of these compounds. The book describes the physico-chemical and biochemical aspects of the plant secondary metabolites along with the chemistry, therapeutics and future perspectives of these plant secondary metabolites. Moreover, the book also discusses about various sources of plant secondary metabolites, and the metabolite determination through various analytical techniques. It further describes the potential applications of plant secondary metabolites as anticancer and chemo preventive agents, their role as cosmetic ingredients and activity in skin cancer therapy. Further chapters emphasize upon the plethora of roles of plant secondary metabolites, including those as antivirals, anti-bacterial, anti-inflammatory drugs, cardioprotective agents etc. The book culminates with chapters on the impact of certain plant secondary metabolites in plant defence and human healthcare. This book is meant for researchers and students in the field of pharmacology and plant sciences. Moreover, this book is also useful for industry experts especially working in the field of herbal therapeutics.

Download or read book Secondary Metabolites of Medicinal Herbs Biochemistry Therapeutics written by M M Abid Ali Khan and published by Discovery Publishing House Pvt Limited. This book was released on 2016-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offer comprehensive studies and covers the structurally diverse secondary metabolites of medicinal herbs including their biochemistry, enthnopharmacological properties and biological activity. Secondary metabolites of medicinal herbs are a treasure trove of novel compounds with potential therapeutic applications.

Download or read book SECONDARY METABOLITES written by Dr. Preethi Kathirvel and published by DARSHAN PUBLISHERS. This book was released on 2021-01-25 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary metabolites are organic compounds that are not directly involved in the normal growth, development, or reproduction of an organism. The secondary metabolites are produced majorly by plants and are called phytochemicals, also by microbes such as bacteria, fungi, algae and so on. These secondary metabolites plays a major role in defensive mechanism in plants, as well as its components are used in food industry, pharmaceuticals and so on. The applications and sources of each secondary metabolite is clearly discussed. We are very much thankful for the publisher who readily accepts and publish this subject. Also the author is very much thankful to her research team Mridul Umesh, Thazeem Basheer, Poorna Chandrika Sabapathy, Sabarinathan Devaraj and Sathishkumar Swamiappan for contributing their help and support for this work. The next edition of this book will more precisely discuss on the extraction and purification of the secondary metabolites.

Download or read book Plant Secondary Metabolities written by Y. M. Shukla and published by New India Publishing. This book was released on 2009-01-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book entitled "Plant Secondary Metabolites" is divided in 11 chapters with broader headings which include introduction, History, Biosynthesis, Essential Oils/Terpenes/Terpenoids, Alkaloids, Glycosides, Gums & Mucilages Oleoresins, Plant amines, Techniques and Biotechnological approaches. 45 tables, 60 figures, chemical equations and colour photographs have been used to make the information useful for under-graduate and post-graduate students of agriculture, ayurveda, pharmacy, naturopathy and home sciences to enrich their knowledge is not only scare but is also scattered and hence an attempt has been made here to provide the best available information to students, researchers and faculties in resembling disciplines under one roof.

Download or read book Secondary Metabolism and Cell Differentiation written by M. Luckner and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Secondary Metabolism and Differentiation In addition to the primary metabolic reactions, which are similar in all living beings (formation and breakdown of nucleic acids and proteins as well as of their precursors, of most carbohy drates, of some carboxylic acids, etc. ), a vast number of metab olic pathways lead to the formation of compounds peculiar to a few species or even to a single chemical race only. These reac tions, in accord with CZAPEK (1921) and PAECH (1950), are summed up under the term "secondary metabolism", and their products are called "secondary metabolites. " The wide variety of secondary products formed in nature includes such well-known groups as alkaloids, antibiotics, cardiac glyco sides, tannins, saponins, volatile oils, and others. A consider able number of them are of economic importance in therapeutics or technology. Although secondary products are produced by micro organisms, higher plants, and animals (cf. LUCKNER, 1972), most of the substances are found in the plant kingdom. The lack of mechanisms for true excretion in higher plants may result in this unequal distribution, the "waste products" of metabolism in plants instead being accumulated in the vacuoles, the cell walls, or in special excretory cells or spaces of the organism ("metabolic excretion," cf. FREY-WYSSLING, 1935, 1970; MOTHES, 1966a, b, 1972; LUCKNER et al. , 1976. Many secondary substances have, however, a direct biologic func tion. They can be regulatory effectors, e. g.

Download or read book Plant Secondary Metabolites Biological and therapeutic significance written by Mohammed Wasim Siddiqui and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Lichen Secondary Metabolites written by Branislav Ranković and published by Springer. This book was released on 2014-12-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book discusses in detail the nature and bioactive properties of lichen secondary metabolites. Their therapeutic potential ranges from antibiotic to antioxidant and from anticarcinogenic to antiviral activity. It further discusses their use in traditional medicine and highlights possible future directions in the study of their pharmaceutical potential.

Download or read book The Biosynthesis of Secondary Metabolites written by R. B. Herbert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This account is primarily intended to be an introduction to the biosynthesis of secondary metabolites. I have also endeavoured, however, to make the book as comprehensive as possIble. This has meant that some of the material has had to be presented in abbrevi ated form. The abbreviated material is largely confined to particular sections of the book. The paragraphs marked with a dagger (t) can be omitted by the reader wishing to acquire a general introduction to the subject. A blend of the most significant and the most recent references is cited to provide the reader with ready access to the primary litera ture. This is clearly most necessary for the material presented in abbreviated form. Relevant reviews are also cited.

Download or read book Secondary Metabolites as Potential Cancer Therapeutic Leads written by Eduardo J.E. Caro-Diaz and published by . This book was released on 2014 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary metabolites generated from natural sources such as microbes, fungi, marine fauna and other microorganism have proven to represent a microcosm of chemical diversity and therefore a great source of novel phamacophoric structures. It is without question that nature in its long biological and chemical evolution has gifted us with beautiful molecular architectures with equally important biological function to provide leads into new and potentially useful biologically active molecules. As a result, it is not surprising that drug discovery efforts, in both industry and academia, have greatly benefited from isolation and characterization of secondary metabolites. For this reason, it is still important to continue our investigative endeavors toward the discovery of novel motifs with undescribed mechanisms of action in the effort to provide new leads towards oncologic small molecule therapeutics. As synthetic chemist secondary metabolites can also encompass lessons about complex reactivity and, with the accelerated development of more sophisticated reactions, can present new challenges to develop more efficient and elaborate strategies towards the total synthesis of complex organic structures. It is both an intricate structural architecture and unprecedented biological activity that provide a solid research project towards the development of a synthetic route of a small molecule secondary metabolite. Englerin A and fusarisetin A both represent all these important attributes and were therefore selected by the primary investigator as synthetic targets for research. Research herein described the work surrounding the formal synthesis of englerin A, the chemical biology in terms of Structural-Activity-Relationship of englerin A, the total synthesis of fusarisetin A, and the chemical biology of fusarisetins. Chapter 1 will narrate the background and research related to synthetic studies and chemical biology of englerin A. Chapter 1 will narrate the background and research related to synthetic studies and chemical biology of fusarisetin A.

Download or read book Secondary Metabolites Bioactive Properties and Therapeutic Applications written by Marcy Prady and published by Hayle Medical. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary metabolites refer to a heterogeneous group of natural metabolic products, which are not directly involved in the normal growth and development, or reproduction of an organism. They can be produced by any life form such as bacteria, fungi, animals or plants. Secondary metabolites are responsible for mediating ecological interactions, which may benefit the organism by increasing its survivability or fertility. They are classified into five main classes according to their structure, function and biosynthesis. These include terpenoids and steroids, fatty acid-derived substances and polyketides, alkaloids, non-ribosomal polypeptides, and enzyme cofactors. There are several medical applications of secondary metabolites due to their immunosuppressant, antitumor, antiprotozoal, antihelminth, antiviral, and anti-aging properties. This book elucidates the concepts and innovative models around prospective developments with respect to secondary metabolites, their bioactive properties, and therapeutic applications. A number of latest researches have been included to keep the readers up-to-date with the latest concepts in this area of study.

Download or read book Plant Secondary Metabolites Volume One written by Taylor & Francis Group and published by Apple Academic Press. This book was released on 2021-03-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, Plant Secondary Metabolites: Volume 1: Biological and Therapeutic Significance, presents important information on the curative and therapeutic roles of secondary metabolites that are present in different natural food groups. The book showcases the applications of herbal-based food group and also includes the effective utility of other plant-based food categories as well. In addition to the clinical role of secondary metabolites, other natural sources, such as micro-algae and bacterial cellulose, are also presented as efficacious sources of functional components.

Download or read book Metabolic Engineering of Plant Secondary Metabolism written by R. Verpoorte and published by Springer. This book was released on 2010-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.

Download or read book Secondary Metabolites written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the producing organism's life cycle. Covers issues related to genetic and antibiotic applications.

Download or read book Secondary Metabolites written by Ramasamy Vijayakumar and published by BoD – Books on Demand. This book was released on 2022-08-17 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of secondary metabolites in three sections: “Introduction”, “Secondary Metabolites: General Reviews and Biotechnological Interventions” and “Plant Secondary Metabolites.” It discusses the antimicrobial, anticancer, and antioxidant activities of secondary metabolites, biotechnological interventions in the production and research of secondary metabolites, and the secondary metabolites of plants.