Download or read book Molecular Determinants of Head and Neck Cancer written by Barbara Burtness and published by Springer. This book was released on 2018-08-03 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. It is estimated that approximately 50,000 patients develop head and neck cancer annually in the United States, of whom approximately 50% succumb to this cancer. For most cases of SCCHN, treatment is multimodal, often combining surgery or irradiation with chemotherapy; even successfully treated patients frequently experience durable and severe side effects. Improving cure rates and reducing chronic morbidity are urgent clinical needs for head and neck cancer. However, in contrast to cancer types such as breast or prostate that have been much studied and have well-defined biology, until recently, relatively few researchers investigated the molecular basis of HNC, making it difficult to design targeted treatments with better efficacy and less debilitating side effects. This volume will provide an overview of the factors contributing to disease pathogenesis, including the recognition of discrete molecular subtypes with distinct etiology, prognosis, and treatment response. This volume will familiarize the reader with the critical signaling pathways and oncogenic drivers for HNC. It will outline the differences between HPV-positive and HPV-negative disease, and how these differences affect treatment choice and outcome. The book will emphasize developments in the past five years, including the growing understanding of the genomic and epigenomic features of the disease based on analysis of next generation sequencing (NGS) data, and timely topics such as the analysis of HNC stem cell populations, non-coding mRNAs, and inflammatory response. It will address exciting new therapeutic approaches such as the use of immunotherapies to treat HNC patients. Overall, the book will provide the reader with current understanding of the biology and treatment of the disease, and describe timely questions that will guide future research aimed at controlling and curing this disease.

Download or read book Lepton Dipole Moments written by B. Lee Roberts and published by World Scientific. This book was released on 2010 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a self-contained description of the measurements of the magnetic dipole moments of the electron and muon, along with a discussion of the measurements of the fine structure constant, and the theory associated with magnetic and electric dipole moments. Also included are the searches for a permanent electric dipole moment of the electron, muon, neutron and atomic nuclei. The related topic of the transition moment for lepton flavor violating processes, such as neutrinoless muon or tauon decays, and the search for such processes are included as well. The papers, written by many of the leading authors in this field, cover both the experimental and theoretical aspects of these topics. Sample Chapter(s). Chapter 1: Historical Introduction to Electric and Mangnetic Moments (367 KB). Contents: Historical Introduction (B L Roberts); Electromagnetic Dipole Moments and New Physics (A Czarnecki & W J Marciano); Lepton g OCo 2 from 1947 to Present (T Kinoshita); Analytic QED Calculations of the Anomalous Magnetic Moment of the Electron (S Laporta & E Remiddi); Measurements of the Electron Magnetic Moment (G Gabrielse); Determining the Fine Structure Constant (G Gabrielse); Helium Fine Structure Theory for the Determination of (K Pachucki & J Sapirstein); Hadronic Vacuum Polarization and the Lepton Anomalous Magnetic Moments (M Davier); The Hadronic Light-by-Light Contribution to a, e (J Prades et al.); General Prescriptions for One-loop Contributions to a e, (K R Lynch); Measurement of the Muon ( g OCo 2) Value (J P Miller et al.); Muon ( g OCo 2) and Physics Beyond the Standard Model (D StAckinger); Probing CP Violation with Electric Dipole Moments (M Pospelov & A Ritz); The Electric Dipole Moment of the Electron (E D Commins & D DeMille); Neutron EDM Experiments (S K Lamoreaux & R Golub); Nuclear Electric Dipole Moments (W C Griffith et al.); EDM Measurements in Storage Rings (B L Roberts et al.); Models of Lepton Flavor Violation (Y Okada); Search for the Charged Lepton-Flavor-Violating Transition Moments l OaAE l OC (Y Kuno). Readership: Researchers and graduate students in particle physics, atomic physics and nuclear physics, as well as experts working in the field

Download or read book Theory And Phenomenology Of Sparticles An Account Of Four dimensional N 1 Supersymmetry In High Energy Physics written by Manuel Drees and published by World Scientific. This book was released on 2005-01-18 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supersymmetry or SUSY, one of the most beautiful recent ideas of physics, predicts sparticles existing as superpartners of particles. This book gives a theoretical and phenomenological account of sparticles. Starting from a basic level, it provides a comprehensive, pedagogical and user-friendly treatment of the subject of four-dimensional N=1 supersymmetry as well as its observational aspects in high energy physics and cosmology. Part One of the book introduces the requisite formal theory, preceded by a discussion of the naturalness problem. Part Two describes the supersymmetrization of the Standard Model of particle interactions as well as the origin of soft supersymmetry breaking and how it can be mediated from higher energies. Search strategies for sparticles, supersymmetric Higgs bosons, nonminimal scenarios and cosmological implications are some of the other topics covered. Novel features of the book include a dictionary between two-component and four-component spinor notation, a step-by-step derivation of the nonrenormalization theorem, an extended discussion of supersymmetric renormalization group evolution, detailed analyses of minimal and nonminimal models with gravity (including anomaly) mediated and gauge mediated supersymmetry breaking as well as elaborate self-contained presentations of collider signals of sparticles plus supersymmetric Higgs bosons and of supersymmetric cosmology. Appendices list all Feynman rules for the vertices of the Minimal Supersymmetric Standard Model.

Download or read book Weak Scale Supersymmetry written by Howard Baer and published by Cambridge University Press. This book was released on 2023-01-31 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This OA text develops the basic concepts of supersymmetry for experimental and phenomenological particle physicists and graduate students.

Download or read book The Anomalous Magnetic Moment of the Muon written by Fred Jegerlehner and published by Springer Science & Business Media. This book was released on 2008 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the present state of knowledge of the anomalous magnetic moment a=(g-2)/2 of the muon. The muon anomalous magnetic moment is one of the most precisely measured quantities in elementary particle physics and provides one of the most stringent tests of relativistic quantum field theory as a fundamental theoretical framework. It allows for an extremely precise check of the standard model of elementary particles and of its limitations.

Download or read book Gauge Theory of Weak Decays written by Andrzej J. Buras and published by Cambridge University Press. This book was released on 2020-07-02 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first advanced, systematic and comprehensive look at weak decays in the framework of gauge theories. Included is a large spectrum of topics, both theoretical and experimental. In addition to explicit advanced calculations of Feynman diagrams and the study of renormalization group strong interaction effects in weak decays, the book is devoted to the Standard Model Effective Theory, dominating present phenomenology in this field, and to new physics models with the goal of searching for new particles and interactions through quantum fluctuations. This book will benefit theorists, experimental researchers, and Ph.D. students working on flavour physics and weak decays as well as physicists interested in physics beyond the Standard Model. In its concern for the search for new phenomena at short distance scales through the interplay between theory and experiment, this book constitutes a travel guide to physics far beyond the scales explored by the Large Hadron Collider at CERN.

Download or read book The Standard Model written by Cliff Burgess and published by Cambridge University Press. This book was released on 2007 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2006 book uses the standard model as a vehicle for introducing quantum field theory.

Download or read book Electroweak Interactions and Unified Theories written by J. Thanh Van Tran and published by Atlantica Séguier Frontières. This book was released on 1988 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Composite Nambu Goldstone Higgs written by Giuliano Panico and published by Springer. This book was released on 2015-11-17 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hierarchy Problem is arguably the most important guiding principle concerning the extension to high-energy scales of the Standard Model (SM) of Fundamental Interactions. Every scenario for addressing this issue unavoidably predicts new physics in the TeV energy range, which is currently being probed directly by the LHC experimental program. Among the possible solutions to the Hierarchy Problem, the scenario of a composite Higgs boson is a very simple idea and a rather plausible picture has emerged over the years by combining the following ingredients: First, the Higgs must be a (pseudo-) Nambu-Goldstone boson, rather than a generic hadron of the new strong sector. Second, through the so-called ‘partial compositeness’, SM particles mix with strong sector resonances with suitable quantum numbers, so that they become a linear combination of elementary and composite degrees of freedom. Recently, general descriptions of the Composite Higgs Scenario were developed which successfully capture the relevant features of this theoretical framework in a largely model-independent way. The present book provides a concise and illustrative introduction to the subject for a broad audience of graduate students and non-specialist researchers in the fields of particle, nuclear and gravitational physics.

Download or read book An Introductory Course of Particle Physics written by Palash B. Pal and published by Taylor & Francis. This book was released on 2014-07-29 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: For graduate students unfamiliar with particle physics, An Introductory Course of Particle Physics teaches the basic techniques and fundamental theories related to the subject. It gives students the competence to work out various properties of fundamental particles, such as scattering cross-section and lifetime. The book also gives a lucid summary of the main ideas involved. In giving students a taste of fundamental interactions among elementary particles, the author does not assume any prior knowledge of quantum field theory. He presents a brief introduction that supplies students with the necessary tools without seriously getting into the nitty-gritty of quantum field theory, and then explores advanced topics in detail. The book then discusses group theory, and in this case the author assumes that students are familiar with the basic definitions and properties of a group, and even SU(2) and its representations. With this foundation established, he goes on to discuss representations of continuous groups bigger than SU(2) in detail. The material is presented at a level that M.Sc. and Ph.D. students can understand, with exercises throughout the text at points at which performing the exercises would be most beneficial. Anyone teaching a one-semester course will probably have to choose from the topics covered, because this text also contains advanced material that might not be covered within a semester due to lack of time. Thus it provides the teaching tool with the flexibility to customize the course to suit your needs.

Download or read book Collider Physics written by Vernon D. Barger and published by CRC Press. This book was released on 2018-05-30 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition of Collider Physics surveys the major developments in theoretical and experimental particle physics and uses numerous illustrations to show how the Standard Model explains the experimental results. Collider Physics offers an introduction to the fundamental particles and their interactions at the level of a lecture course for graduate students, with emphasis on the aspects most closely related to colliders--past, present, and future. It includes expectations for new physics associated with Higgs bosons and supersymmetry. This resourceful book shows how to make practical calculations and serves a dual purpose as a textbook and a handbook for collider physics phenomenology.

Download or read book Yet Another Introduction to Dark Matter written by Martin Bauer and published by Springer. This book was released on 2019-06-11 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dark matter is a frequently discussed topic in contemporary particle physics. Written strictly in the language of particle physics and quantum field theory, these course-based lecture notes focus on a set of standard calculations that students need in order to understand weakly interacting dark matter candidates. After introducing some general features of these dark matter agents and their main competitors, the Higgs portal scalar and supersymmetric neutralinos are introduced as our default models. In turn, this serves as a basis for exploring four experimental aspects: the dark matter relic density extracted from the cosmic microwave background; indirect detection including the Fermi galactic center excess; direct detection; and collider searches. Alternative approaches, like an effective theory of dark matter and simplified models, naturally follow from the discussions of these four experimental directions.

Download or read book Particles and Nuclei written by Bogdan Povh and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition includes new developments, in particular a new section on the double beta decay including a discussion of the possibility of a neutrinoless decay and its implications for the standard model.

Download or read book Astroparticle Physics written by Claus Grupen and published by Springer Nature. This book was released on 2020-01-27 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the branch of astronomy in which processes in the universe are investigated with experimental methods employed in particle-physics experiments. After a historical introduction the basics of elementary particles, Explains particle interactions and the relevant detection techniques, while modern aspects of astroparticle physics are described in a chapter on cosmology. Provides an orientation in the field of astroparticle physics that many beginners might seek and appreciate because the underlying physics fundamentals are presented with little mathematics, and the results are illustrated by many diagrams. Readers have a chance to enter this field of astronomy with a book that closes the gap between expert and popular level.

Download or read book Physical Foundations of Cosmology written by Viatcheslav Mukhanov and published by Cambridge University Press. This book was released on 2005-11-10 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflationary cosmology has been developed over the last twenty years to remedy serious shortcomings in the standard hot big bang model of the universe. This textbook, first published in 2005, explains the basis of modern cosmology and shows where the theoretical results come from. The book is divided into two parts; the first deals with the homogeneous and isotropic model of the Universe, the second part discusses how inhomogeneities can explain its structure. Established material such as the inflation and quantum cosmological perturbation are presented in great detail, however the reader is brought to the frontiers of current cosmological research by the discussion of more speculative ideas. An ideal textbook for both advanced students of physics and astrophysics, all of the necessary background material is included in every chapter and no prior knowledge of general relativity and quantum field theory is assumed.

Download or read book Search for Flavor Changing Neutral Current Top Quark Decays t Hq with H bb in pp Collisions at s 8 TeV with the ATLAS Detector written by Shota Tsiskaridze and published by Springer. This book was released on 2017-08-02 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This PhD thesis focuses on the search for flavor-changing neutral currents in the decay of a top quark to an up-type quark (q = u, c) and the Standard Model Higgs boson, where the Higgs boson decays to bb. Further, the thesis presents the combination of this search for top quark pair events with other ATLAS searches – in the course of which the most restrictive bounds to date on tqH interactions were obtained. Following on from the discovery of the Higgs boson, it is particularly important to measure the Yukawa couplings of the Standard Model fermions; these parameters may provide crucial insights to help solve the flavor puzzle and may help reveal the presence of new physics before it is directly observed in experiments.

Download or read book Supersymmetry and String Theory written by Michael Dine and published by Cambridge University Press. This book was released on 2007-01-04 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed dramatic developments in the field of theoretical physics. This book is a comprehensive introduction to these recent developments. It contains a review of the Standard Model, covering non-perturbative topics, and a discussion of grand unified theories and magnetic monopoles. It introduces the basics of supersymmetry and its phenomenology, and includes dynamics, dynamical supersymmetry breaking, and electric-magnetic duality. The book then covers general relativity and the big bang theory, and the basic issues in inflationary cosmologies before discussing the spectra of known string theories and the features of their interactions. The book also includes brief introductions to technicolor, large extra dimensions, and the Randall-Sundrum theory of warped spaces. This will be of great interest to graduates and researchers in the fields of particle theory, string theory, astrophysics and cosmology. The book contains several problems, and password protected solutions will be available to lecturers at www.cambridge.org/9780521858410.