Download or read book Scale up in Chemical Engineering written by Marko Zlokarnik and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the important task of the scale-up of processes from the laboratory to the production scale, this easily comprehensible and transparent book is divided into two sections. The first part details the theoretical principles, introducing the subject for readers without a profound prior knowledge of mathematics. It discusses the fundamentals of dimensional analysis, the treatment of temperature-dependent and rheological material values and scale-up where model systems or not available or only partly similar. All this is illustrated by 20 real-world examples, while 25 exercises plus solutions new to this edition practice and monitor learning. The second part presents the individual basic operations and covers the fields of mechanical, thermal, and chemical process engineering with respect to dimensional analysis and scale-up. The rules for scale-up are given and discussed for each operation. Other additions to this second edition are dimensional analysis of pelleting processes, and a historical overview of dimensional analysis and modeling, while all the chapters have been updated to take the latest literature into account. Written by a specialist with more than 40 years of experience in the industry, this book is specifically aimed at students as well as practicing engineers, chemists and process engineers already working in the field.
Download or read book Scale up Engineering written by Johann Stichlmair and published by Begell House Publishers. This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an extremely effective tool for engineers of all disciplines. It is based on the description of technical objects by complete sets of dimensionless numbers. The scale-up laws are helpful in solving engineering problems by simple or small-scale experiments. Thus, the dimensionless numbers and scale-up laws are used in many fields of natural and engineering sciences.
Download or read book Scale Up Processes written by Jamal Chaouki and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-09-20 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Common scale-up methods are conventional where the blind piloting is essential. This imposes huge investment and leads to failures mostly in solid processing. However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting. With these situations in mind, current digitalization outlook and computational facilities, we proposed and developed a novel iterative scale up method with case studies which highly expedites the process innovation through the following key sequences:
Download or read book Pilot Plants Models and Scale up Methods in Chemical Engineering written by Robert Edgeworth Johnstone and published by . This book was released on 1957 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Industrial Process Scale up written by Jan Harmsen and published by Elsevier. This book was released on 2013-04-25 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. - Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up - Explains each stage of the innovation funnel: research, development, demonstration, commercial implementation for any process type and branch - Based on industrial experiences and practices, which reduces the risks of commercial scale implementation of new processes to acceptable levels and reduces cost and time of process innovation - Very clear, attractive layout, using text boxes that contain clarifying notes and additional information on specific topics, which makes it a quick reference of main subjects and additional information
Download or read book Dimensional Analysis and Scale up in Chemical Engineering written by Marko Zlokarnik and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Chemical Process Engineers face complex design and research problems. Temperature-dependent physical properties and non-Newtonian flow behavior of substances in a process cannot be predicted by numerical mathematics. Scaling-up equipment for processing can often only be done with partial similarity methods. Standard textbooks often neglect topics like dimensional analysis, theory of similarity and scale-up. This book fills this gap! It is aimed both at university students and the process engineer. It presents dimensional analysis very comprehensively with illustrative examples of mechanical, thermal and chemical processes.
Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-08 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.
Download or read book Chemical Projects Scale Up written by Joe M. Bonem and published by Elsevier. This book was released on 2018-05-31 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Projects Scale Up: How to Go from Laboratory to Commercial covers the chemical engineering steps necessary for taking a laboratory development into the commercial world. The book includes the problems associated with scale up, equipment sizing considerations, thermal characteristics associated with scale up, safety areas to consider, recycling considerations, operability reviews and economic viability. In addition to the process design aspects of commercializing the laboratory development, consideration is given to the utilization of a development in an existing plant. - Explains how heat removal for exothermic reactions can be scaled up - Outlines how a reactor can be sized from batch kinetic data - Discusses how the plant performance of a new catalyst can be evaluated - Presents how the economics of a new product/process can be developed - Discusses the necessary evaluation of recycling in commercial plants
Download or read book Scale up Methodology for Chemical Processes written by Jean-Paul Euzen and published by Editions TECHNIP. This book was released on 1993 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Having gained considerable experience in process development at the Institut FranCais du PEtrole, the authors present a design framework, a review of the available means of investigation, and several examples illustrating their methodology of industrial process scale up. The salient feature of the book is the fact that it addresses a subject which is vital in view of its economic repercussions, yet relatively unknown in technical and scientific circles, due to the confidentiality surrounding it.Contents: 1. Main guidelines of the methodology. 2. Various types of model. 3. Pilot plants and mock-ups. 4. Experimental techniques. 5. Applications to industrial process development. 6. Conclusions. References. Index.
Download or read book Food Processing Operations and Scale up written by Kenneth J. Valentas and published by CRC Press. This book was released on 1990-11-19 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for students and practitioners who have a basic education in chemical engineering or food science. Contains basic information in each area and describes some of the fundamental ideas of processing development and design. Examines the food industry structure, how it works, consumer products,
Download or read book Bioreaction Engineering Principles written by Jens Nielsen and published by Springer. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.
Download or read book Chemical Reactor Design written by E. B. Nauman and published by . This book was released on 1987 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Essentials of Fluidization Technology written by John R. Grace and published by John Wiley & Sons. This book was released on 2020-06-15 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and clear treatment of the fundamentals of fluidization, with a view to its applications in the process and energy industries.
Download or read book Engineering Principles in Biotechnology written by Wei-Shou Hu and published by John Wiley & Sons. This book was released on 2017-11-13 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a short introduction to the engineering principles of harnessing the vast potential of microorganisms, and animal and plant cells in making biochemical products. It was written for scientists who have no background in engineering, and for engineers with minimal background in biology. The overall subject dealt with is process. But the coverage goes beyond the process of biomanufacturing in the bioreactor, and extends to the factory of cell’s biosynthetic machinery. Starting with an overview of biotechnology and organism, engineers are eased into biochemical reactions and life scientists are exposed to the technology of production using cells. Subsequent chapters allow engineers to be acquainted with biochemical pathways, while life scientist learn about stoichiometric and kinetic principles of reactions and cell growth. This leads to the coverage of reactors, oxygen transfer and scale up. Following three chapters on biomanufacturing of current and future importance, i.e. cell culture, stem cells and synthetic biology, the topic switches to product purification, first with a conceptual coverage of operations used in bioseparation, and then a more detailed analysis to provide a conceptual understanding of chromatography, the modern workhorse of bioseparation. Drawing on principles from engineering and life sciences, this book is for practitioners in biotechnology and bioengineering. The author has used the book for a course for advanced students in both engineering and life sciences. To this end, problems are provided at the end of each chapter.
Download or read book Handbook of Industrial Mixing written by Edward L. Paul and published by John Wiley & Sons. This book was released on 2004-02-17 with total page 1450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Industrial Mixing will explain the difference and uses of a variety of mixers including gear mixers, top entry mixers, side entry mixers, bottom entry mixers, on-line mixers, and submerged mixers The Handbook discusses the trade-offs among various mixers, concentrating on which might be considered for a particular process. Handbook of Industrial Mixing explains industrial mixers in a clear concise manner, and also: * Contains a CD-ROM with video clips showing different type of mixers in action and a overview of their uses. * Gives practical insights by the top professional in the field. * Details applications in key industries. * Provides the professional with information he did receive in school
Download or read book Scaleup of Chemical Processes written by Attilio Bisio and published by Wiley-Interscience. This book was released on 1985-07-25 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this book is on the technical factors that are critical to th e design and startup of a commercial manufacturing facility.
Download or read book Scaling Chemical Processes written by Jonathan Worstell and published by Butterworth-Heinemann. This book was released on 2016-06-08 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scaling Chemical Processes: Practical Guides in Chemical Engineering is one of a series of short texts that each provides a focused introductory view on a single subject. The full library spans the main topics in the chemical process industries for engineering professionals who require a basic grounding in various related topics. They are 'pocket publications' that the professional engineer can easily carry with them or access electronically while working. Each text is highly practical and applied, and presents first principles for engineers who need to get up to speed in a new area fast. The focused facts provided in each guide will help you converse with experts in the field, attempt your own initial troubleshooting, check calculations, and solve rudimentary problems. This book discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant. It bases scaling on similarity principles and uses dimensional analysis to derive the dimensionless parameters necessary to ensure a successful chemical process development program. This series is fully endorsed and co-branded by the IChemE, and they help to promote the series. - Offers practical, short, concise information on the basics to help you get an answer or teach yourself a new topic quickly - Includes industry examples to help you solve real world problems - Provides key facts for professionals in convenient single subject volumes - Discusses scaling chemical processes from a laboratory through a pilot plant to a commercial plant
