Download or read book Scale up and Chemical Process for Microbial Production of Plant Derived Bioactive Compounds written by Yongjun Wei and published by Elsevier. This book was released on 2024-03-20 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limited th - Introduces the scale-up and chemical process development for microbial production of plant-derived bioactive compounds - Covers the useful and effective sustainable and commercial production of plant-derived bioactive compounds - Provides a guide for commercial production of plant-derived bioactive compounds and their uses for human welfare

Download or read book Biotechnological Production of Bioactive Compounds written by Madan L. Verma and published by Elsevier. This book was released on 2019-07-20 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits "bioactives'' from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. - Outlines technological advances in bioactives extraction - Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes - Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

Download or read book Water Extraction of Bioactive Compounds written by Herminia Dominguez and published by Elsevier. This book was released on 2017-09-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Academic Press. This book was released on 2011-05-02 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry.NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics

Download or read book Nutraceuticals Production from Plant Cell Factory written by Tarun Belwal and published by Springer Nature. This book was released on 2022-06-22 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on in vitro techniques and challenges of producing nutraceutical compounds from plant cells. In addition, it provides an overview of different biosynthesis pathways and their modulation through cell culture techniques for the production of nutraceutical compounds in high quantity and quality. It also includes the assessment of the factors influencing production and advances in cell culture techniques, including the scale-up approach using bioreactors. Lastly it provides valuable suggestion for future research.

Download or read book Bioprospecting of Microbial Diversity written by Pradeep Verma and published by Elsevier. This book was released on 2022-02-01 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprospecting of Microbial Diversity: Challenges and Applications in Biochemical Industry, Agriculture and Environment Protection gives a detailed insight into the utilization of microorganisms or microorganism-based bioactive compounds for the development of sustainable approaches, covering recent advances and challenges in the production and recovery of bioactive compounds such as enzymes, biopesticides, biofertilizers, biosensors, therapeutics, nutraceutical and pharmaceutical products. The challenges associated with the different approaches of microbial bioprospecting along with possible solutions to overcome these limitations are addressed. Further, the application of microbe-based products in the area of environmental pollution control and developing greener technologies are discussed. Providing valuable insight into the basics of microbial prospecting, the book covers established knowledge as well as genomic-based technological advancements to offer a better understanding of its application to various industries, promoting the commercialization of microbial-derived bioactive compounds and their application in biochemical industries, agriculture, and environmental protection studies. - Describes the advanced techniques available for microbial bioprospecting for large-scale industrial production of bioactive compounds - Presents recent advances and challenges for the application of microbe-based products in agriculture and environment pollution control - Provides knowledge of microbial production of bioenergy and high-value compounds such as nutraceuticals and pharmaceuticals

Download or read book Production of Biomass and Bioactive Compounds Using Bioreactor Technology written by Kee-Yoeup Paek and published by Springer. This book was released on 2014-09-30 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. This book emphasizes on the fundamental topics like designing of bioreactors for plant cell and organ cultures, various types of bioreactors including stirred tank, airlift, photo-bioreactor, disposable bioreactor used for plant cell and organ cultures and the advantages and disadvantages of bioreactor cultures. Various strategies for biomass production and metabolite accumulation have been discussed in different plant systems including Korean/Chinese ginseng, Siberian ginseng, Indian ginseng, Echinacea, St. John’s wort, Noni, Chinese licorice, Caterpillar fungus and microalgae. Researches on the industrial application of plant cells and organs with future prospects as well as the biosafety of biomass produced in bioreactors are also described. The topics covered in this book, such as plant cell and organ cultures, hairy roots, bioreactors, bioprocess techniques, will be a valuable reference for plant biotechnologists, plant biologists, pharmacologists, pharmacists, food technologists, nutritionists, research investigators of healthcare industry, academia, faculty and students of biology and biomedical sciences. The multiple examples of large-scale applications of cell and organ cultures will be useful and significant to industrial transformation and real commercialization.

Download or read book Development of the Nordic Bioeconomy written by Lange, Lene and published by Nordic Council of Ministers. This book was released on 2016-02-04 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2014 NCM initiated a new project: “Test centers for green energy solutions – Biorefineries and Business needs” to strengthen Nordic bioeconomy by identifying potentials, obstacles, needs and opportunities. The Nordic bioeconomy has a unique profile: Upgrade of many types of residues also to higher value products; good collaboration between private and public sector; R&D efforts in all Nordic countries. However, shortcomings were also identified: few activities across Nordic countries beyond designated Nordic programs; too few upscaling facilities; need for improved framework conditions (within regulatory and market stimulus) for biobased products. This report is part of the Nordic Prime Ministers' green growth initiative: “The Nordic Region – leading in green growth” - read more in the web magazine “Green Growth the Nordic Way” at www.nordicway.org or at www.norden.org/greengrowth

Download or read book Nanoscale Fabrication Optimization Scale up and Biological Aspects of Pharmaceutical Nanotechnology written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2017-12-11 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. - Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products - Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years - Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Download or read book Natural Bioactive Compounds written by Rajeshwar P. Sinha and published by Academic Press. This book was released on 2020-10-06 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. - Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants - Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances - Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)

Download or read book Industrialization of Biology written by National Research Council and published by National Academies Press. This book was released on 2015-06-29 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

Download or read book Microbial Sensing in Fermentation written by Satinder K. Brar and published by John Wiley & Sons. This book was released on 2019-01-04 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the fundamental molecular mechanisms in fermentation and explores the microbiology of fermentation technology and industrial applications Microbial Sensing in Fermentation presents the fundamental molecular mechanisms involved in the process of fermentation and explores the applied art of microbiology and fermentation technology. The text contains descriptions regarding the extraordinary sensing ability of microorganisms towards small physicochemical changes in their surroundings. The contributors — noted experts in the field — cover a wide range of topics such as microbial metabolism and production (fungi, bacteria, yeast etc); refined and non-refined carbon sources; bioprocessing; microbial synthesis, responses and performance; and biochemical, molecular and extra/intracellular controlling. This resource contains a compilation of literature on biochemical and cellular level mechanisms for microbial controlled production and includes the most significant recent advances in industrial fermentation. The text offers a balanced approach between theory and practical application, and helps readers gain a clear understanding of microbial physiological adaptation during fermentation and its cumulative effect on productivity. This important book: Presents the fundamental molecular mechanisms involved in microbial sensing in relation to fermentation technology Includes information on the significant recent advances in industrial fermentation Contains contributions from a panel of highly-respected experts in their respective fields Offers a resource that will be essential reading for scientists, professionals and researchers from academia and industry with an interest in the biochemistry and microbiology of fermentation technology Written for researchers, graduate and undergraduate students from diverse backgrounds, such as biochemistry and applied microbiology, Microbial Sensing in Fermentation offers a review of the fundamental molecular mechanisms involved in the process of fermentation.

Download or read book Bioprospecting of Microbial Resources for Agriculture Environment and Bio chemical Industry written by Pinki Saini and published by Springer Nature. This book was released on with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Lactic Acid Fermentation of Fruits and Vegetables written by Spiros Paramithiotis and published by CRC Press. This book was released on 2017-02-03 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lactic acid fermentation has been practiced for thousands of years mainly to preserve surplus and perishable foodstuff and also to enhance them organoleptically. Lactic acid fermentation of fruits and vegetables is no exception, leading to the production of a wide range of products, some of which are now considered as characteristic of certain geographical areas and cultures. The aim of this book is to collect, present, and discuss all available information regarding lactic acid fermentation of fruits and vegetables. For this purpose, an international group of experts was invited to contribute their knowledge and experience in a highly informative and comprehensive way. The book consists of fourteen chapters. The first five chapters integrate aspects that apply to all products. Then, chapters 6 to 9 are dedicated to products that have met commercial significance and have been extensively studied, i.e. sauerkraut, kimchi, fermented cucumbers and olives. In chapters 10 to 13, regional products with great potential from Asia, Europe and Africa, as well as lactic acid fermented juices and smoothies, are presented and thoroughly discussed. Finally, chapter 14 discusses the fields in which intensive study is expected to take place in the coming years.

Download or read book Conservation and Sustainable Utilization of Bioresources written by Swapna Thacheril Sukumaran and published by Springer Nature. This book was released on 2023-01-05 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together chapters related to sustainable utilization of biological resources, including in situ and ex situ conservation of rare, endangered, and threatened plants. The title also gives a special emphasis on marine sponges and mangrove ecosystems, which are two important untapped potential resources of the marine ecosystem and play a key role in maintaining the marine ecosystem. There is an urgent need for the conservation, exploration and utilization of bioresources for the growth and survival of human beings. Due to the significant reduction in biological resources, many countries are developing strategic action plans for the conservation and sustainable use of biological resources. That is where this book fills the gap by discussing the significant development of new products and methodologies for sustainable utilization of these resources. This book also unveils a world of novel bioactive molecules from medicinal plants and the marine ecosystem and explains how drug design pipelines can advance modern drug development. The target audiences for this book include biodiversity researchers who are working on technology and bioresource management issues and faculty and students in the environment research areas and Biodiversity conservation.

Download or read book Microbial Bioprocessing of Agri food Wastes written by Gustavo Molina and published by CRC Press. This book was released on 2023-06-16 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview of recent advances in the valorization of agri-food waste and discusses the main process conditions needed to overcome the difficulties of using waste as alternative raw materials. It also discusses specific methodologies, opportunistic microbes for biomass valorization, the sustainable production of agri-food waste, as well as examines the assessment and management of bioactive molecules production from microbial-valorization of agri-food waste. The authors provide technical concepts on the production of various bio-products and their commercial interest including agri-food waste utilization in the microbial synthesis of proteins, the valorization of horticulture waste, the sustainable production of pectin via microbial fermentation, as well as other food and pharmacological applications. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals and researchers. Explores recent advances in the valorization of agri-food waste Provides technical concepts on the production of various bio-products of commercial interest Discusses the main process conditions to overcome the difficulties of using waste as alternative raw materials Introduces technical-economic details on the advantages and disadvantages of exploring the waste recovery chain Explores the main technological advances in the recovery of residues in functional products

Download or read book Sustainable Green Synthesised Nano Dimensional Materials for Energy and Environmental Applications written by Sathish-Kumar Kamaraj and published by CRC Press. This book was released on 2024-12-05 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing interest in applying the UN's sustainable development goals to a variety of sectors. One can use certain principles of green chemistry in the emerging fields of nanoscience and nanotechnology. The green chemistry approach focuses on the creation of nanodimensional materials that have a low environmental impact, are cost-effective, and have no negative consequences on the environment. This book aims to summarise the different alternative green chemical routes. Furthermore, the book describes the use of nano-dimensional materials for sustainable energy generation and environmental remediation applications.