Download or read book SARS CoV 2 Variants and Global Population Vulnerability written by Vivek P. Chavda and published by CRC Press. This book was released on 2024-07-05 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: SARS-CoV-2, the coronavirus responsible for COVID-19, wreaked havoc on the world; it could both spread easily and mutate rapidly, leading to the decrease in the effectiveness of newly developed vaccines over time. The detection of these mutated variants and the development of more efficient vaccines requires significant effort and increased knowledge in this field. This new book, SARS-CoV-2 Variants and Global Population Vulnerability: Diagnostic Strategies, Vaccine Development, and Therapeutic Management, provides detailed and systemic information regarding the biology and immunophysiology of SARS-CoV-2 and highlights the global vulnerability of the world population to SARS-CoV-2 infection and COVID-19. The book covers different aspects pertaining to the SARS-CoV-2 variants and their relation to global vulnerability. Chapters discuss the diagnostics, vaccine development, and therapeutic management starting from the zoonotic origin, organization, and transmission of SARS-CoV-2, lifestyle and immunophysiology of the virus, detection and diagnosis techniques, and analytical techniques. The book also observes the global impact of Delta and Omicron SARS-CoV-2 variants. It looks at the drug repurposing and new drug discovery routines for the emerging variants. It presents strategies for fast-track vaccine development, the roles of nasal vaccines and nucleic acid vaccines for COVID-19 management, monoclonal antibody therapy for the diseases management, along with the use of dietary supplements and nutraceuticals, herbal drugs, and other alternative remedies for COVID-19 management. The book also considers the social and environmental impacts of SARS-CoV-2 variants and the current challenges, outlining aspects that can help in developing more efficacious means for controlling SARS-CoV-2 in the future. Key highlights: Discusses SARS-CoV-2 variants, diagnosis strategies, vaccine development, and the therapeutic management of the disease Provides comprehensive coverage of SARS-CoV-2 virus and variants With its unique and thorough take on the subject, this book is an important resource of know-how for investigators working in this area. Professionals from the pharmaceutical industry as well as students, research scholars, doctors, and other healthcare professionals will find this book of particular value.

Download or read book The Threat of Pandemic Influenza written by Institute of Medicine and published by National Academies Press. This book was released on 2005-04-09 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

Download or read book Apollo s Arrow written by Nicholas A. Christakis and published by Hachette UK. This book was released on 2020-10-27 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A piercing and scientifically grounded look at the emergence of the coronavirus pandemic and how it will change the way we live—"excellent and timely." (The New Yorker) Apollo's Arrow offers a riveting account of the impact of the coronavirus pandemic as it swept through American society in 2020, and of how the recovery will unfold in the coming years. Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague—an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species. Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

Download or read book Flu written by Gina Kolata and published by Farrar, Straus and Giroux. This book was released on 2011-04-01 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

Download or read book The Impact of COVID 19 on Vulnerable Populations written by Echu Liu and published by Frontiers Media SA. This book was released on 2023-10-05 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Modernizing Global Health Security to Prevent Detect and Respond written by Scott J.N. McNabb and published by Elsevier. This book was released on 2023-02-15 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modernizing Global Health Security to Prevent, Detect, and Respond explores the history of public health surveillance, current governance and legal structures. The book explores global public health and the challenges in preventing, detecting and responding to emerging threats. It describes a vision for the future of global public health, with an aim of charting a way forward that includes an understanding that epidemics are expected, but pandemics are preventable. Major topics covered include global health security, epidemic/pandemic prevention, detection and response, One Health and zoonosis, virus outbreaks of Ebola, Zika, MERS-CoV and COVID-19, manmade public health threats and environmental health, and more. This book provides the context researchers, practitioners and graduate-level students need in public health to better understand what was, what is and what could be for global health security. Highlights emerging threats to public health (e.g., disease, climate change, antibiotic resistance, PFAS) Discusses new approaches to global health security Leverages technological innovations to advance public health Includes practical examples and case studies from around the world

Download or read book A Proposal to End the COVID 19 Pandemic written by Ruchir Agarwal and published by International Monetary Fund. This book was released on 2021-05-19 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Urgent steps are needed to arrest the rising human toll and economic strain from the COVID-19 pandemic that are exacerbating already-diverging recoveries. Pandemic policy is also economic policy as there is no durable end to the economic crisis without an end to the health crisis. Building on existing initiatives, this paper proposes pragmatic actions at the national and multilateral level to expeditiously defeat the pandemic. The proposal targets: (1) vaccinating at least 40 percent of the population in all countries by the end of 2021 and at least 60 percent by the first half of 2022, (2) tracking and insuring against downside risks, and (3) ensuring widespread testing and tracing, maintaining adequate stocks of therapeutics, and enforcing public health measures in places where vaccine coverage is low. The benefits of such measures at about $9 trillion far outweigh the costs which are estimated to be around $50 billion—of which $35 billion should be paid by grants from donors and the residual by national governments potentially with the support of concessional financing from bilateral and multilateral agencies. The grant funding gap identified by the Access to COVID-19 Tools (ACT) Accelerator amounts to about $22 billion, which the G20 recognizes as important to address. This leaves an estimated $13 billion in additional grant contributions needed to finance our proposal. Importantly, the strategy requires global cooperation to secure upfront financing, upfront vaccine donations, and at-risk investment to insure against downside risks for the world.

Download or read book Biodiversity and Health written by Serge Morand and published by Elsevier. This book was released on 2017-11-27 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a gap between the ecology of health and the concepts supported by international initiatives such as EcoHealth, One Health or Planetary Health; a gap which this book aims to fill. Global change is accelerated by problems of growing population, industrialization and geopolitics, and the world’s biodiversity is suffering as a result, which impacts both humans and animals. However, Biodiversity and Health offers the unique opportunity to demonstrate how ecological, environmental, medical and social sciences can contribute to the improvement of human health and wellbeing through the conservation of biodiversity and the services it brings to societies. This book gives an expansive and integrated overview of the scientific disciplines that contribute to the connection between health and biodiversity, from the evolutionary ecology of infectious and non-infectious diseases to ethics, law and politics. Presents the first book to give a broad and integrated overview of the scientific disciplines that contribute to health From evolutionary ecology, to laws and policies, this book explores the links between health and biodiversity Demonstrates how ecological sciences, environmental sciences, medical sciences, and social sciences may contribute to improve human health

Download or read book How to Prevent the Next Pandemic written by Bill Gates and published by Vintage. This book was released on 2022-05-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Governments, businesses, and individuals around the world are thinking about what happens after the COVID-19 pandemic. Can we hope to not only ward off another COVID-like disaster but also eliminate all respiratory diseases, including the flu? Bill Gates, one of our greatest and most effective thinkers and activists, believes the answer is yes. The author of the #1 New York Times best seller How to Avoid a Climate Disaster lays out clearly and convincingly what the world should have learned from COVID-19 and what all of us can do to ward off another catastrophe like it. Relying on the shared knowledge of the world’s foremost experts and on his own experience of combating fatal diseases through the Gates Foundation, Gates first helps us understand the science of infectious diseases. Then he shows us how the nations of the world, working in conjunction with one another and with the private sector, how we can prevent a new pandemic from killing millions of people and devastating the global economy. Here is a clarion call—strong, comprehensive, and of the gravest importance.

Download or read book Global Economic Prospects June 2021 written by World Bank and published by World Bank Publications. This book was released on 2021-08-03 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world economy is experiencing a very strong but uneven recovery, with many emerging market and developing economies facing obstacles to vaccination. The global outlook remains uncertain, with major risks around the path of the pandemic and the possibility of financial stress amid large debt loads. Policy makers face a difficult balancing act as they seek to nurture the recovery while safeguarding price stability and fiscal sustainability. A comprehensive set of policies will be required to promote a strong recovery that mitigates inequality and enhances environmental sustainability, ultimately putting economies on a path of green, resilient, and inclusive development. Prominent among the necessary policies are efforts to lower trade costs so that trade can once again become a robust engine of growth. This year marks the 30th anniversary of the Global Economic Prospects. The Global Economic Prospects is a World Bank Group Flagship Report that examines global economic developments and prospects, with a special focus on emerging market and developing economies, on a semiannual basis (in January and June). Each edition includes analytical pieces on topical policy challenges faced by these economies.

Download or read book Blue Marble Health written by Peter J. Hotez and published by JHU Press. This book was released on 2016-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do diseases of poverty afflict more people in wealthy countries than in the developing world? In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor’s National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States’ economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world’s neglected diseases—which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis—are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as “blue marble health,” through which he asserts that poor people living in wealthy countries account for most of the world’s poverty-related illness. He explores the current state of neglected diseases in such disparate countries as Mexico, South Korea, Argentina, Australia, the United States, Japan, and Nigeria. By crafting public policy and relying on global partnerships to control or eliminate some of the world’s worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy. Clear, compassionate, and timely, Blue Marble Health is a must-read for leaders in global health, tropical medicine, and international development, along with anyone committed to helping the millions of people who are caught in the desperate cycle of poverty and disease.

Download or read book SARS CoV 2 Spike Protein Convergent Evolution written by Daniele Focosi and published by Springer Nature. This book was released on 2021-10-11 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

Download or read book Economic Policy for a Pandemic Age written by Monica de Bolle and published by Peterson Institute for International Economics. This book was released on 2021-04-05 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global health and economic threats from the COVID-19 pandemic are not yet behind us. While the development of multiple safe and highly effective vaccines in less than a year is cause for hope, several significant dangers to recovery of global health and income are still clear and present: New concerning variants of SARS-CoV-2, the virus that causes COVID-19, continue to emerge at an alarming rate in different parts of the world; at the same time, vaccine rollouts have been shockingly inefficient even in some rich countries, while much of the developing world waits in line behind them for vaccines to arrive. The Briefing covers several policy areas in which cooperative forward-looking policy action will materially improve our chances of truly escaping today's pandemic and making future pandemics less costly.

Download or read book SARS CoV2 COVID 19 Pandemic Control and Prevention written by Laurens Holmes, Jr. and published by Taylor & Francis. This book was released on 2023-09-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive text to provide not only a detailed explanation of how the SARS-CoV2 (COVID-19) virus is spread within human populations, but also an epidemiological analysis and interpretation of viral pandemics to enable better measures for prevention and control. Providing an introduction to the physiology of both the human immune system and the SARS-CoV2 virus, specifically the virus’s replicative potential and our own vulnerability, the book offers an in-depth understanding of how the pandemic evolved. It also highlights the aberrant epigenomic mechanistic process in pathogenic microbe’s replication and survival, implying gene and environment interaction that affected different populations. Citing a range of environmental conditions, from structural and systemic racism to malnutrition and low-socioeconomic status, the book examines how these factors exacerbated existing health disparities, resulting in a disproportionate burden of morbidity and mortality on certain social groups. Also providing invaluable guidance on how future iterations of this pandemic may be better prevented and controlled, this will be a defining book for students, researchers and professionals within Public Health and Clinical Medicine to better understand the SARS-CoV2 (COVID-19) virus, and how to protect the most vulnerable social groups.

Download or read book Syndemic Suffering written by Emily Mendenhall and published by Routledge. This book was released on 2016-06-16 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a major contribution to the study of diabetes, this book is the first to analyze the disease through a syndemic framework, offering a model study of chronic disease disparity among the poor in high income countries.

Download or read book Modeling Infectious Diseases in Humans and Animals written by Matt J. Keeling and published by Princeton University Press. This book was released on 2011-09-19 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control

Download or read book Virology E Book written by Stephen N J Korsman and published by Elsevier Health Sciences. This book was released on 2012-08-17 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, highly accessible introduction to medical virology, incorporating essential basic principles as well as a systematic review of viruses and viral diseases. It pays particular attention to developments in anti-viral therapy that are becoming increasingly effective in modern medicine. It is an ideal textbook for the information-overloaded student and an invaluable everyday companion for the busy professional who needs a good understanding of the current state of medical virology. In keeping with the highly successful format of other Illustrated Colour Texts, it presents the subject as a series of succinct 2 page 'learning units', using a superb collection of clear illustrations and clinical photographs, concise yet comprehensive text and key point boxes to aid quick access to information and examination preparation. So whether you are a medical student, junior doctor, medical scientist, trainee in infectious diseases or student on another allied medical course, this book is here to make your life easier! It will also provide a very solid foundation for any who plan to delve deeper into this fascinating field. - Part of the popular Illustrated Colour Text series - Information presented in double page spreads for easy learning - Highly illustrated with both full colour graphics and clinical photographs - Each spread includes a key point box for exam preparation