Download or read book Sample Size Determination and Power written by Thomas P. Ryan and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive approach to sample size determination and power with applications for a variety of fields Sample Size Determination and Power features a modern introduction to the applicability of sample size determination and provides a variety of discussions on broad topics including epidemiology, microarrays, survival analysis and reliability, design of experiments, regression, and confidence intervals. The book distinctively merges applications from numerous fields such as statistics, biostatistics, the health sciences, and engineering in order to provide a complete introduction to the general statistical use of sample size determination. Advanced topics including multivariate analysis, clinical trials, and quality improvement are addressed, and in addition, the book provides considerable guidance on available software for sample size determination. Written by a well-known author who has extensively class-tested the material, Sample Size Determination and Power: Highlights the applicability of sample size determination and provides extensive literature coverage Presents a modern, general approach to relevant software to guide sample size determination including CATD (computer-aided trial design) Addresses the use of sample size determination in grant proposals and provides up-to-date references for grant investigators An appealing reference book for scientific researchers in a variety of fields, such as statistics, biostatistics, the health sciences, mathematics, ecology, and geology, who use sampling and estimation methods in their work, Sample Size Determination and Power is also an ideal supplementary text for upper-level undergraduate and graduate-level courses in statistical sampling.
Download or read book Determining Sample Size and Power in Research Studies written by J. P. Verma and published by Springer Nature. This book was released on 2020-07-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses sample size and power in the context of research, offering valuable insights for graduate and doctoral students as well as researchers in any discipline where data is generated to investigate research questions. It explains how to enhance the authenticity of research by estimating the sample size and reporting the power of the tests used. Further, it discusses the issue of sample size determination in survey studies as well as in hypothesis testing experiments so that readers can grasp the concept of statistical errors, minimum detectable difference, effect size, one-tail and two-tail tests and the power of the test. The book also highlights the importance of fixing these boundary conditions in enhancing the authenticity of research findings and improving the chances of research papers being accepted by respected journals. Further, it explores the significance of sample size by showing the power achieved in selected doctoral studies. Procedure has been discussed to fix power in the hypothesis testing experiment. One should usually have power at least 0.8 in the study because having power less than this will have the issue of practical significance of findings. If the power in any study is less than 0.5 then it would be better to test the hypothesis by tossing a coin instead of organizing the experiment. It also discusses determining sample size and power using the freeware G*Power software, based on twenty-one examples using different analyses, like t-test, parametric and non-parametric correlations, multivariate regression, logistic regression, independent and repeated measures ANOVA, mixed design, MANOVA and chi-square.
Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Download or read book Sample Size Methodology written by M. M. Desu and published by Elsevier. This book was released on 2012-12-02 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important problems in designing an experiment or a survey is sample size determination and this book presents the currently available methodology. It includes both random sampling from standard probability distributions and from finite populations. Also discussed is sample size determination for estimating parameters in a Bayesian setting by considering the posterior distribution of the parameter and specifying the necessary requirements. The determination of the sample size is considered for ranking and selection problems as well as for the design of clinical trials. Appropriate techniques for attacking the general question of sample size determination in problems of estimation, tests of hypotheses, selection, and clinical trial design are all presented, and will help the reader in formulating an appropriate problem of sample size and in obtaining the solution. The book can be used as a text in a senior-level or a graduate course on sample size methodology. Annotated list of tables in appendixSupplemental problems at the end of book
Download or read book Sample Size Calculations written by Paul Mathews and published by Mathews Malnar and Bailey. This book was released on 2010 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sample Size Calculations: Practical Methods for Engineers and Scientists presents power and sample size calculations for common statistical analyses including methods for means, standard deviations, proportions, counts, regression, correlation, and measures of agreement. Topics of special interest to quality engineering professionals include designed experiments, reliability studies, statistical process control, acceptance sampling, process capability analysis, statistical tolerancing, and gage error studies. The book emphasizes approximate methods, but exact methods are presented when the approximate methods fail. Monte Carlo and bootstrap methods are introduced for situations that don't satisfy the assumptions of the analytical methods. Solutions are presented for more than 170 example problems and solutions for selected example problems using PASS, MINITAB, Piface, and R are posted on the Internet.
Download or read book Sample Size Calculations in Clinical Research written by Shein-Chung Chow and published by CRC Press. This book was released on 2017-08-15 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ..." – Journal of the Royal Statistical Society Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation. Features: Compares the relative merits and disadvantages of statistical methods for sample size calculations Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.
Download or read book Determining Sample Size written by Patrick Dattalo and published by Oxford University Press. This book was released on 2008-01-11 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: A researchers decision about the sample to draw in a study may have an enormous impact on the results, and it rests on numerous statistical and practical considerations that can be difficult to juggle. Computer programs help, but no single software package exists that allows researchers to determine sample size across all statistical procedures. This pocket guide shows social work students, educators, and researchers how to prevent some of the mistakes that would result from a wrong sample size decision by describing and critiquing four main approaches to determining sample size. In concise, example-rich chapters, Dattalo covers sample-size determination using power analysis, confidence intervals, computer-intensive strategies, and ethical or cost considerations, as well as techniques for advanced and emerging statistical strategies such as structural equation modeling, multilevel analysis, repeated measures MANOVA and repeated measures ANOVA. He also offers strategies for mitigating pressures to increase sample size when doing so may not be feasible. Whether as an introduction to the process for students or as a refresher for experienced researchers, this practical guide is a perfect overview of a crucial but often overlooked step in empirical social work research.
Download or read book Sample Size Determination in Clinical Trials with Multiple Endpoints written by Takashi Sozu and published by Springer. This book was released on 2015-08-20 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates recent methodological developments for calculating the sample size and power in trials with more than one endpoint considered as multiple primary or co-primary, offering an important reference work for statisticians working in this area. The determination of sample size and the evaluation of power are fundamental and critical elements in the design of clinical trials. If the sample size is too small, important effects may go unnoticed; if the sample size is too large, it represents a waste of resources and unethically puts more participants at risk than necessary. Recently many clinical trials have been designed with more than one endpoint considered as multiple primary or co-primary, creating a need for new approaches to the design and analysis of these clinical trials. The book focuses on the evaluation of power and sample size determination when comparing the effects of two interventions in superiority clinical trials with multiple endpoints. Methods for sample size calculation in clinical trials where the alternative hypothesis is that there are effects on ALL endpoints are discussed in detail. The book also briefly examines trials designed with an alternative hypothesis of an effect on AT LEAST ONE endpoint with a prespecified non-ordering of endpoints.
Download or read book Sample Size Determination in Health Studies written by S. Kaggwa Lwanga and published by . This book was released on 1991 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual presents the practical and statistical information needed to help investigators decide how large a sample to select from a population targeted for a health study or survey. Designed to perform a "cookbook" function, the book uses explanatory text and abundant tabular calculations to vastly simplify the task of determining the minimum sample size needed to obtain statistically valid results. The objective is to assist those investigators, undertaking health studies at local or district level, who lack detailed knowledge of statistical methodology. Acknowledging that the size of a sample will depend on the aims, nature, and scope of the study, the first part of the book provides a practical farmework for working through the steps of sample size determination once a proposed study and its objectives have been clearly defined. The second part of the book features more than 50 pages of tables that enable the reader to determine the sample size required, under simple random sampling, in a given type of study without recourse to complicated calculations.
Download or read book Small Sample Size Solutions written by Rens van de Schoot and published by Routledge. This book was released on 2020-02-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers often have difficulties collecting enough data to test their hypotheses, either because target groups are small or hard to access, or because data collection entails prohibitive costs. Such obstacles may result in data sets that are too small for the complexity of the statistical model needed to answer the research question. This unique book provides guidelines and tools for implementing solutions to issues that arise in small sample research. Each chapter illustrates statistical methods that allow researchers to apply the optimal statistical model for their research question when the sample is too small. This essential book will enable social and behavioral science researchers to test their hypotheses even when the statistical model required for answering their research question is too complex for the sample sizes they can collect. The statistical models in the book range from the estimation of a population mean to models with latent variables and nested observations, and solutions include both classical and Bayesian methods. All proposed solutions are described in steps researchers can implement with their own data and are accompanied with annotated syntax in R. The methods described in this book will be useful for researchers across the social and behavioral sciences, ranging from medical sciences and epidemiology to psychology, marketing, and economics.
Download or read book How to Practice Academic Medicine and Publish from Developing Countries written by Samiran Nundy and published by Springer Nature. This book was released on 2021-10-23 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.
Download or read book Adequacy of Sample Size in Health Studies written by Stanley Lemeshow and published by Wiley. This book was released on 1990-01-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical rather than theoretical, it provides epidemiologists and other health workers with a good basic knowledge of sampling principles and methods and their potential in the medical field. Focusing on the determination of adequate sample sizes under different situations, the book is divided into two parts; the first provides solutions to typical problems of various survey and study designs, and the second offers a clear, concise exposition of the theory behind the processes of determining sample size. Features many reference tables.
Download or read book Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research written by Chul Ahn and published by CRC Press. This book was released on 2014-12-09 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement. Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
Download or read book Institutional Animal Care and Use Committee Guidebook written by and published by . This book was released on 2002 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantifying the User Experience written by Jeff Sauro and published by Morgan Kaufmann. This book was released on 2016-07-12 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantifying the User Experience: Practical Statistics for User Research, Second Edition, provides practitioners and researchers with the information they need to confidently quantify, qualify, and justify their data. The book presents a practical guide on how to use statistics to solve common quantitative problems that arise in user research. It addresses questions users face every day, including, Is the current product more usable than our competition? Can we be sure at least 70% of users can complete the task on their first attempt? How long will it take users to purchase products on the website? This book provides a foundation for statistical theories and the best practices needed to apply them. The authors draw on decades of statistical literature from human factors, industrial engineering, and psychology, as well as their own published research, providing both concrete solutions (Excel formulas and links to their own web-calculators), along with an engaging discussion on the statistical reasons why tests work and how to effectively communicate results. Throughout this new edition, users will find updates on standardized usability questionnaires, a new chapter on general linear modeling (correlation, regression, and analysis of variance), with updated examples and case studies throughout. Completely updated to provide practical guidance on solving usability testing problems with statistics for any project, including those using Six Sigma practices Includes new and revised information on standardized usability questionnaires Includes a completely new chapter introducing correlation, regression, and analysis of variance Shows practitioners which test to use, why they work, and best practices for application, along with easy-to-use Excel formulas and web-calculators for analyzing data Recommends ways for researchers and practitioners to communicate results to stakeholders in plain English
Download or read book Statistical Rules of Thumb written by Gerald van Belle and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition: "For a beginner [this book] is a treasure trove; for an experienced person it can provide new ideas on how better to pursue the subject of applied statistics." —Journal of Quality Technology Sensibly organized for quick reference, Statistical Rules of Thumb, Second Edition compiles simple rules that are widely applicable, robust, and elegant, and each captures key statistical concepts. This unique guide to the use of statistics for designing, conducting, and analyzing research studies illustrates real-world statistical applications through examples from fields such as public health and environmental studies. Along with an insightful discussion of the reasoning behind every technique, this easy-to-use handbook also conveys the various possibilities statisticians must think of when designing and conducting a study or analyzing its data. Each chapter presents clearly defined rules related to inference, covariation, experimental design, consultation, and data representation, and each rule is organized and discussed under five succinct headings: introduction; statement and illustration of the rule; the derivation of the rule; a concluding discussion; and exploration of the concept's extensions. The author also introduces new rules of thumb for topics such as sample size for ratio analysis, absolute and relative risk, ANCOVA cautions, and dichotomization of continuous variables. Additional features of the Second Edition include: Additional rules on Bayesian topics New chapters on observational studies and Evidence-Based Medicine (EBM) Additional emphasis on variation and causation Updated material with new references, examples, and sources A related Web site provides a rich learning environment and contains additional rules, presentations by the author, and a message board where readers can share their own strategies and discoveries. Statistical Rules of Thumb, Second Edition is an ideal supplementary book for courses in experimental design and survey research methods at the upper-undergraduate and graduate levels. It also serves as an indispensable reference for statisticians, researchers, consultants, and scientists who would like to develop an understanding of the statistical foundations of their research efforts. A related website www.vanbelle.org provides additional rules, author presentations and more.
Download or read book Practical Tools for Designing and Weighting Survey Samples written by Richard Valliant and published by Springer Science & Business Media. This book was released on 2013-05-16 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survey sampling is fundamentally an applied field. The goal in this book is to put an array of tools at the fingertips of practitioners by explaining approaches long used by survey statisticians, illustrating how existing software can be used to solve survey problems, and developing some specialized software where needed. This book serves at least three audiences: (1) Students seeking a more in-depth understanding of applied sampling either through a second semester-long course or by way of a supplementary reference; (2) Survey statisticians searching for practical guidance on how to apply concepts learned in theoretical or applied sampling courses; and (3) Social scientists and other survey practitioners who desire insight into the statistical thinking and steps taken to design, select, and weight random survey samples. Several survey data sets are used to illustrate how to design samples, to make estimates from complex surveys for use in optimizing the sample allocation, and to calculate weights. Realistic survey projects are used to demonstrate the challenges and provide a context for the solutions. The book covers several topics that either are not included or are dealt with in a limited way in other texts. These areas include: sample size computations for multistage designs; power calculations related to surveys; mathematical programming for sample allocation in a multi-criteria optimization setting; nuts and bolts of area probability sampling; multiphase designs; quality control of survey operations; and statistical software for survey sampling and estimation. An associated R package, PracTools, contains a number of specialized functions for sample size and other calculations. The data sets used in the book are also available in PracTools, so that the reader may replicate the examples or perform further analyses.