Download or read book Salvinorin written by D. M. Turner and published by Panther Press (TN). This book was released on 1996 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Current Topics in Opioid Research written by Lawrence Toll and published by Frontiers Media SA. This book was released on 2019-11-27 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Drugs of the Dreaming written by Gianluca Toro and published by Simon and Schuster. This book was released on 2007-05-21 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive guide to oneirogens--naturally occurring substances that induce and enhance dreaming • Includes extensive monographs on dream-enhancing substances derived from plant, animal, and human sources • Presents the results of scientific experiments on the effects of using oneirogens • Shows how studies in this area of ethnobotany can yield a scientific understanding of the mysterious mechanism of dreams Oneirogens are plant and animal substances that have long been used to facilitate powerful and productive dreaming. From the beginning of civilization, dreams have guided the inner and outer life of human beings both in relation to each other and to the divine. For centuries shamans have employed oneirogens in finding meaning and healing in their dreams. Drugs of the Dreaming details the properties and actions of these dream allies, establishing ethnobotanical profiles for 35 oneirogens, including those extracted from organic sources--such as Calea zacatechichi (dream herb or “leaf of the god”), Salvia divinorum, and a variety of plants from North and South America and the Pacific used in shamanic practices--as well as synthetically derived oneirogens. They explain the historical use of each oneirogen, its method of action, and what light it sheds on the scientific mechanism of dreaming. They conclude that oneirogens enhance the comprehensibility and facility of the dream/dreamer relationship and hold a powerful key for discerning the psychological needs and destinies of dreamers in the modern world.

Download or read book Drug Addiction written by Rao S. Rapaka and published by Springer Science & Business Media. This book was released on 2008-06-19 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of physiological, biochemical, and genetic pathways underlying drug addiction, and resultant efforts to develop novel treatment strategies dealing with drug addiction and other CNS disorders where the neurophysiological processes overlap, such as treatment of pain. The volume focuses on the translation of fundamental addiction research to a variety of treatments and brings together scientists with wide ranging expertise.

Download or read book Opioids and Their Receptors written by Mariana Spetea and published by MDPI. This book was released on 2020-12-18 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interest in opioids such as morphine, the prototypical opioid ligand, has been maintained through the years. The identification of endogenous opioids and their receptors (mu, delta, kappa, and nociceptin), molecular cloning, and the elucidation of the crystal structures of opioid receptors represent key milestones in opioid research. The opioid system modulates numerous pharmacological responses, with therapeutic (i.e., analgesia) and detrimental side effects (i.e., addiction). The medical use and misuse of opioids have dramatically increased, leading to the 21st century opioid crisis. This book presents recent developments in opioid drug discovery, specifically in the medicinal chemistry and pharmacology of new ligands targeting the opioid receptors as effective and safe therapeutics for human diseases. Furthermore, it draws a special attention to advancing concepts and strategies in opioid drug discovery to mitigate opioid liabilities. The diversity among the discussed topics is a testimony to the complexity of the opioid system, which results from the expression, regulation, and functional role of ligands and receptors. The array of multidisciplinary research areas illustrates the rapidly developing basic research and translational activities in opioid drug discovery. This book will serve as a useful reference while also stimulating continued research in the chemistry and pharmacology of opioids and their receptors, with the prospect of developing improved therapies for human diseases, but also improving health and quality of life in general.

Download or read book The Effects of Drug Abuse on the Human Nervous System written by Bertha Madras and published by Elsevier. This book was released on 2013-11-15 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. - A comprehensive reference on the effects of drug addiction on the human nervous system - Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs - Includes foundational science chapters on the biology of addiction - Details challenges in diagnosis and treatment options

Download or read book Kratom and Other Mitragynines written by Robert B. Raffa and published by CRC Press. This book was released on 2014-10-29 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature's only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds-those derived from the plant Mitragyna speciosa. This plan

Download or read book Handbook of Medical Hallucinogens written by Charles S. Grob and published by Guilford Publications. This book was released on 2023-01-13 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook reviews promising applications of psychedelics in treatment of such challenging psychiatric problems as posttraumatic stress disorder, major depression, substance use disorders, and end-of-life anxiety. Experts from multiple disciplines synthesize current knowledge on psilocybin, MDMA, ketamine, and other medical hallucinogens. The volume comprehensively examines these substances' neurobiological mechanisms, clinical effects, therapeutic potential, risks, and anthropological and historical contexts. Coverage ranges from basic science to practical clinical considerations, including patient screening and selection, dosages and routes of administration, how psychedelic-assisted sessions are structured and conducted, and management of adverse reactions.

Download or read book Shamanic Quest for the Spirit of Salvia written by Ross Heaven and published by Simon and Schuster. This book was released on 2013-05-20 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first practical guide to the transformative uses of salvia • Explains how salvia connects you with your higher purpose and aids you in envisioning your unique path in life • Describes appropriate methods of use, a shamanic diet to increase effectiveness, and the meaning of the symbols experienced during salvia’s ecstatic embrace • Explores recent clinical research into salvia’s long-term positive psychological effects and its potential as a treatment for Alzheimer’s, depression, and addiction Salvia divinorum has been used since ancient times by the Mazatec shamans of Mexico for divination, vision quests, and healing. Known by many names--nearly all associated with the Virgin Mary, who has come to symbolize the spirit of salvia--this plant ally is now regarded as the most powerful natural hallucinogen. Providing the first practical guide to the shamanic, spiritual, and therapeutic uses of salvia, Ross Heaven shares his in-depth quest to connect with the spirit of this plant teacher. He explores recent clinical research into its many long-term psychological effects, such as increased insight and self-confidence, improved mood and concentration, and feelings of calmness and connection with nature, as well as salvia’s potential for combating diseases like Alzheimer’s, depression, and even cocaine addiction. Reviewing the traditional Mazatec ceremonies surrounding salvia’s harvest and use, Heaven describes appropriate methods of consumption, typical dosages, and the shamanic diet he used to increase salvia’s effectiveness. Examining firsthand accounts of salvia journeys from around the world, he decodes the meaning of the symbolic images experienced during salvia’s ecstatic embrace and details the interplay between salvia and the lucid dreaming state. Comparing salvia to ayahuasca and the San Pedro cactus, Heaven explains that salvia’s greatest strength as a shamanic plant ally lies in its ability to connect you with your higher purpose and aid you in envisioning your unique path in life.

Download or read book Exploration of Salvinorin A Chemical Space written by Sarah Jane Hill and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The salvinorins serve as templates for next generation analgesics, antipruritics and dissociative hallucinogens via selective and potent agonism of the kappa-opioid receptor (KOR). In contrast to most opioids, the salvinorins lack basic amines and bind with high affinity and selectivity via complex polyoxygenated scaffolds that have frustrated deep-seated modification by synthesis. Here we describe a short asymmetric synthesis that relies on a sterically-confined organocatalyst to dissociate acidity from reactivity and effect Robinson annulation of an unactivated nucleophile / unstable electrophile pair. Combined with a cobalt-catalyzed polarized diene-alkyne cycloaddition, the route allows divergent access to a focused library of salvinorins. We appraise the synthesis by its generation of multiple analogs that exceed the potency, selectivity, stability and functional bias of salvinorin A itself.

Download or read book The Psychedelic Handbook written by Rick Strassman and published by Simon and Schuster. This book was released on 2022-08-09 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn everything you need to know about psychedelics with this ultimate guide packed with information on popular psychedelic drugs like psilocybin, ketamine, MDMA, DMT and LSD—plus practical tips for microdosing and how to safely "trip"—from bestselling author Dr. Rick Strassman. Entering the world of psychedelic drugs can be challenging, and many aren’t sure where to start. As research continues to expand and legalization looms on the horizon for psychedelics like psilocybin, you may need a guide to navigate what psychedelics are, how they work, and their potential benefits and risks. The Psychedelic Handbook is a complete manual that is accessible to anyone with an interest in these “mind-manifesting” substances. Packed with information on psilocybin, LSD, DMT/ayahuasca, mescaline/peyote, ketamine, MDMA, ibogaine, 5-methoxy-DMT (“the toad”), and Salvia divinorum/salvinorin A, this book is your ultimate reference for understanding the science and history of psychedelics; discovering their potential to treat depression, PTSD, substance abuse, and other disorders, as well as to increase wellness, creativity, and meditation; learning how to safely trip and explaining what we know about microdosing; and recognizing and caring for negative reactions to psychedelics. Clinical research psychiatrist, founding figure of the American psychedelic research renaissance, and best-selling author of DMT: The Spirit Molecule, Dr. Rick Strassman shares his experience and perspectives as neither advocate nor foe of psychedelics in order to help readers understand the effects of these remarkable drugs.

Download or read book A Literature Review on the Status and Effects of Salvia Divinorum on Cognitive Affective and Behavioral Functioning written by Parker L. Mott and published by Universal-Publishers. This book was released on 2011-12-02 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The ASAM Principles of Addiction Medicine written by Shannon C. Miller and published by Lippincott Williams & Wilkins. This book was released on 2024-02-15 with total page 5147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Addiction Medicine, 7th ed is a fully reimagined resource, integrating the latest advancements and research in addiction treatment. Prepared for physicians in internal medicine, psychiatry, and nearly every medical specialty, the 7th edition is the most comprehensive publication in addiction medicine. It offers detailed information to help physicians navigate addiction treatment for all patients, not just those seeking treatment for SUDs. Published by the American Society of Addiction Medicine and edited by Shannon C. Miller, MD, Richard N. Rosenthal, MD, Sharon Levy, MD, Andrew J. Saxon, MD, Jeanette M. Tetrault, MD, and Sarah E. Wakeman, MD, this edition is a testament to the collective experience and wisdom of 350 medical, research, and public health experts in the field. The exhaustive content, now in vibrant full color, bridges science and medicine and offers new insights and advancements for evidence-based treatment of SUDs. This foundational textbook for medical students, residents, and addiction medicine/addiction psychiatry fellows, medical libraires and institution, also serves as a comprehensive reference for everyday clinical practice and policymaking. Physicians, mental health practitioners, NP, PAs, or public officials who need reference material to recognize and treat substance use disorders will find this an invaluable addition to their professional libraries.

Download or read book Issues in Clinical Psychology Psychiatry and Counseling 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 2917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Clinical Psychology, Psychiatry, and Counseling: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Clinical Psychology, Psychiatry, and Counseling. The editors have built Issues in Clinical Psychology, Psychiatry, and Counseling: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Clinical Psychology, Psychiatry, and Counseling in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Clinical Psychology, Psychiatry, and Counseling: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Discoveries In Pharmacological Sciences written by Popat N Patil and published by World Scientific. This book was released on 2012-04-16 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This unique book, Discoveries in Pharmacological Sciences, contains the history of herbal medicine as it emerged about 5,000 years ago. Recent discoveries in genetics are integrated with the observations in the past. An understanding of the history of drugs and toxic chemicals is essential for the proper utility of these substances by the population at large. The book is written with the purpose to familiarize drug research of the investigators in chemical, pharmaceutical, pharmacological, and biomedical sciences. It is important to note that plants containing morphine, quinine, physostigmine, pilocarpine, atropine, d-tubocurarine, reserpine, tetrahydrocannabinol, cardiac glycosides, ephedrine and colchicine were used by various cultures for centuries. Since 1805 pure, active, therapeutic constituents were isolated and chemically characterized. Parallel to these developments, the science of human anatomy, physiology, biochemistry, genetics and pharmacology has advanced. New synthetic drugs were discovered. The chemistry of perfumes and sensory functions including memory were elucidated. The history of fascinating discoveries made by scientists of Nobel repute was documented. Better testing methods were developed. The causes of many diseases were better understood. Drug laws were instituted a century ago. The pharmaceutical industry flourished. The text provides a panoramic view of the understanding of when, where, who, how and why drugs were developed. Educational aspects of teaching pharmacological sciences are reviewed. The historical account will be invaluable to graduate students and creative scientists, who can prepare for the future.The book will serve to enhance the cumulative scientific knowledge of the investigators in drug discovery. It contains a well integrated wealth of information in drug sciences and pharmacotherapeutics. The time, place and the human side of investigators, their portraits with biographical sketches are presented.The reading of Discoveries in Pharmacological Sciences will satisfy the intellectual curiosity of investigators. Understanding of Discoveries in Pharmacological Sciences will provide a platform to judge the importance of the personalized medicine of tomorrow. Scattered classical information about drug sciences is effectively condensed here. The development of the scientific thoughts and creativity of the investigators through the ages in drug research are presented admirably.

Download or read book Medical Toxicology of Drug Abuse written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.

Download or read book Salvia Divinorum written by J. D. Arthur and published by Simon and Schuster. This book was released on 2010-02-17 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: One man’s personal journey through the unparalleled trance states of salvia • Originally published as Peopled Darkness • Contains real-life descriptions of salvia-induced visionary experiences • Offers guidance for the responsible use of this psychoactive plant • Explores the shamanic awareness associated with salvia Salvia divinorum, which recently entered the visionary pharmacopoeia of the modern world, has been used for centuries in the shamanic practices of the Mazatec Indians of Oaxaca, Mexico, for healing and divination. A member of the Mint family, Salvia divinorum--“diviner’s sage”--offers a new doorway to the visionary pursuit of higher spiritual and meditative states. With repeated sessions using salvia over the course of several years, J. D. Arthur began returning each time to the same inner landscape where he found himself entering a unique state of thought-free, or “thoughtless,” awareness. There he accessed a mode of “dream language” that communicated an exquisite constellation of detailed meanings swiftly and flawlessly. His repeated immersion in these states of trance, as well as his analysis of their approach and withdrawal, led to a profound reassessment of the nature of normal perception and a reevaluation of what we refer to as the real world. With true-life descriptions of salvia-induced visionary states, this book offers a detailed experiential analysis for those interested in exploring salvia in their quest for higher knowledge.