Download or read book Redox and Osmoregulation in Saccharomyces Cerevisiae written by Ricky Ansell and published by . This book was released on 1997 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Redox Control in Yeast Saccharomyces Cerevisiae written by Alaattin Kaya and published by . This book was released on 2013 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: The influence of redox homeostasis on aging and DNA stability is a complex one. To address how thiol oxidoreductases affect these processes, we analyzed the functions of methionine sulfoxide reductases (Msrs) and thiol peroxidases in Saccharomyces cerevisiae. Yeast cells deficient in Msrs did not grow on respiratory carbon sources and had low levels of cytochrome c, indicating impairment of mitochondrial function. Lifespan analyses revealed a decrease in both chronological and replicative lifespan of Msr deficient cells. The data suggested that regulation of aging by Msrs could be linked to mitochondrial function. We further analyzed how thiol peroxidases affect genome stability and aging. We developed a S. cerevisiae strain lacking all 8 thiol peroxidase genes (Delta8) and subjected its multiple independent lines to long-term experimental evolution, followed by genome sequencing. Compared to wild type cells, Delta8 lines showed a 15-fold increase in point mutations and a significant increase in indels. Further gene expression analyses revealed dysregulation of DNA replication and repair genes in Delta8 cells. These data suggested that thiol peroxidases protect genomes by both reducing hydroperoxides and regulating cellular homeostasis through control of gene expression. To determine how genomic instability is linked to aging, we took advantage of the yeast replicative aging model assessing the frequency and type of spontaneous mutations. We isolated daughter cells at different replicative age from wild type and Delta8 cells and sequenced their genomes. Mutation rate increased as a function of age and it was higher in Delta8 than in wild type cells. However, the observed low numbers of mutations were inconsistent with the idea that mutations cause or contribute to aging. Overall, we demonstrated how deficiency in non-essential, yet critical and conserved oxidoreductase functions, leads to increased mutational load and decreased cell fitness and how these features are linked to the aging process.
Download or read book Integrative Analysis of Osmoregulation in Yeast Saccharomyces Cerevisiae written by and published by . This book was released on 2014 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Yeast Sugar Metabolism written by Friedrich K. Zimmermann and published by CRC Press. This book was released on 1997-03-10 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.
Download or read book Yeast Stress Responses written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellular stress responses, and the completion of the yeast genome sequence has only added to its power This volume comprehensively reviews both the basic features of the yeast genral stress response and the specific adapations to different stress types (nutrient depletion, osmotic and heat shock as well as salt and oxidative stress). It includes the latest findings in the field and discusses the implications for the analysis of stress response mechanisms in higher eukaryotes as well.
Download or read book Lignocellulosic Biomass Refining for Second Generation Biofuel Production written by Ponnusami V. and published by CRC Press. This book was released on 2023-07-14 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes technological advancements for bioethanol production from lignocellulosic waste Provides a roadmap for the production and utilization of 2G biofuels Introduces the strategic role of metabolic engineering in the development of 2G biofuels Discusses technological advancements, life cycle assessment and prospects Explores novel potential lignocellulosic biomass for 2G biofuels
Download or read book Biotechnology of Yeasts and Filamentous Fungi written by Andriy A. Sibirny and published by Springer. This book was released on 2017-06-12 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview on biotechnological applications of unicellular and multicellular fungi in a variety of industrial branches. Targeted genetic and metabolic engineering of fungi allows production of native and transgenic enzymes and proteins in industrial scales. Those most prominently find application in biorefineries for the production of value-added chemicals and biofuels, in the pharmaceutical industry as well as in biomedicine. Each chapter is dedicated to applications and potential beneficial use of particular strains of yeasts and filamentous fungi and their produced biomolecules. The book targets researchers from both academia and industry and graduate students working in microbial biotechnology.
Download or read book Molecular Mechanisms in Yeast Carbon Metabolism written by Jure Piškur and published by Springer. This book was released on 2014-05-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. A central biochemical activity in the yeast cell is the metabolism of carbon compounds, providing energy for the whole cell, and precursors for any of the final fermentation products. A complex set of genes and regulatory pathways controls the metabolism of carbon compounds, from nutrient sensing, signal transduction, transcription regulation and post-transcriptional events. Recent advances in comparative genomics and development of post-genomic tools have provided further insights into the network of genes and enzymes, and molecular mechanisms which are responsible for a balanced metabolism of carbon compounds in the yeast cell, and which could be manipulated in the laboratory to increase the yield and quality of yeast biotech products. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.
Download or read book Metabolism and Molecular Physiology of Saccharomyces Cerevisiae written by J. Richard Dickinson and published by CRC Press. This book was released on 2004-04-27 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the best-selling first edition, much has been discovered about Saccharomyces cerevisiae, the single-celled fungus commonly known as baker's yeast or brewer's yeast that is the basis for much of our understanding of the molecular and cellular biology of eukaryotes. This wealth of new research data demands our attention and r
Download or read book Proceedings of the 2012 International Conference on Applied Biotechnology ICAB 2012 written by Tong-Cun Zhang and published by Springer Science & Business Media. This book was released on 2013-11-29 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012. It provides not only a platform for domestic and foreign researchers to exchange their ideas and experiences with the application-oriented research of biotechnology, but also an opportunity to promote the development and prosperity of the biotechnology industry. The proceedings of ICAB 2012 mainly focus on the world's latest scientific research and techniques in applied biotechnology, including Industrial Microbial Technology, Food Biotechnology, Pharmaceutical Biotechnology, Environmental Biotechnology, Marine Biotechnology, Agricultural Biotechnology, Biological Materials and Bio-energy Technology, Advances in Biotechnology, and Future Trends in Biotechnology. These proceedings are intended for scientists and researchers engaging in applied biotechnology. Professor Pingkai Ouyang is the President of the Nanjing University of Technology, China. Professor Tongcun Zhang is the Director of the Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education at the College of Bioengineering, Tianjin University of Science and Technology, China. Dr. Samuel Kaplan is a Professor at the Department of Microbiology & Molecular Genetics at the University of Texas at Houston Medical School, Houston, Texas, USA. Dr. Bill Skarnes is a Professor at Wellcome Trust Sanger Institute, United Kingdom.
Download or read book Molecular Mechanisms of Water Transport Across Biological Membranes written by Wilfred D. Stein and published by Gulf Professional Publishing. This book was released on 2002-04-02 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume looks at water movements from a wide range of levels. It examines how water interacts with the major components of the cell, including proteins and lipids. It discusses how water moves across cell membranes by diffusion, how it is chanelled across these membranes or, in certain cases, pumped across, and how water movements are controlled. This book demonstrates how water and ion movements are closely linked in order to provide a better understanding of their behavior. *Essential Physical chemistry of water at biological interfaces *Up-to-date reviews of water behavior in cells *Water in integrated systems *Current information on water channels across membranes
Download or read book Protein Isoforms Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Isoforms—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Protein Isoforms in a concise format. The editors have built Protein Isoforms—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Protein Isoforms in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Protein Isoforms—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Molecular Biology and Physiology of Water and Solute Transport written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous. In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport" to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.
Download or read book Yeast Stress Responses written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2003-01-17 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellular stress responses, and the completion of the yeast genome sequence has only added to its power This volume comprehensively reviews both the basic features of the yeast genral stress response and the specific adapations to different stress types (nutrient depletion, osmotic and heat shock as well as salt and oxidative stress). It includes the latest findings in the field and discusses the implications for the analysis of stress response mechanisms in higher eukaryotes as well.
Download or read book The Molecular Biology of Schizosaccharomyces pombe written by Richard Egel and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fission yeast Schizosaccharomyces pombe is the favoured tool of many productive research groups throughout the world, serving as a useful model for fundamental principles and mechanisms, such as genome organization, differential gene regulation, cell-cycle control, signal transduction, or cellular morphogenesis. This book collates the current state of knowledge derived from molecular studies in this simple eukaryotic microorganism. The entire sequence of its genome has been completed, emphasizing the comparative value and model status of this yeast. The individual chapters, highlighting up-to-date views on prominent aspects of molecular organization, were written by active research scientists, presenting the results of their investigations to other workers in neighbouring fields. This book intends to serve the fission yeast community as a handy source of reference for years to come. It will also be of particular value to the ever-increasing number of researchers starting to look into fission yeast affairs for comparative reasons from other platforms of molecular genetics and cell biology.
Download or read book The Fungal Kingdom written by Joseph Heitman and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
