Download or read book Neurodevelopment and Schizophrenia written by Matcheri S. Keshavan and published by Cambridge University Press. This book was released on 2004-11-18 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was originally published in 2004 and concerns developmental neurobiology. In the decade preceding publication, developmental neurobiology made important strides towards elucidating the pathophysiology of psychiatric disorders. Nowhere has this link between basic science and clinical insights become clearer than in the field of schizophrenia research. Each contributor to this volume provides a fresh overview of the relevant research, including directions for further investigation. The book begins with a section on advances in developmental neurobiology. This is followed by sections on etiological and pathophysiological developments, and models that integrate this knowledge. The final section addresses the clinical insights that emerge from the developmental models. This book will be valuable to researchers in psychiatry and neurobiology, students in psychology, and all mental health practitioners.
Download or read book Recent Advances in the Biology of Schizophrenia written by Thomas A. Ban and published by Charles C. Thomas Publisher. This book was released on 1973 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in the Neurobiology of Schizophrenia written by Johan A. den Boer and published by . This book was released on 1995-07-11 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed major advances in the study of neuroscience which have increased our understanding of the relationship between cerebral processes and behavioural, cognitive and emotional disorders. This series aims to monitor important research developments in the field of biological psychiatry and their relevance to clinical practice. Since the 1950s there has been significant progress in our understanding of the neurobiology of schizophrenia. This important volume illustrates these new developments, particularly in terms of pharmacotherapeutics, pathogenesis and research methodology. Eminent scientists from around the world discuss conceptual issues, epidemiology, genetic analysis of psychotic disturbances, neuropathological changes and brain imaging studies, atypical neuroleptics, psychopharmacology of schizophrenia, neuropeptide involvement, neurophysiology and information processing in schizophrenia. Also highlighted are the similarities between childhood developmental disorders and schizophrenia, as well as the relatively neglected area of biological factors in childhood psychosis and their predictive value in adult psychopathology. Psychiatrists, neuroscientists, pharmacologists, psychologists, physicians and general practitioners will find this authoritative state-of-the-art review important and informative reading.
Download or read book Neuroinflammation and Cognition written by Ashok Kumar and published by Frontiers Media SA. This book was released on 2019-03-22 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.
Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Download or read book The Neuropathology of Schizophrenia written by Paul J. Harrison and published by . This book was released on 2000-08-24 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
Download or read book Schizophrenia written by Steven M. Silverstein and published by MIT Press. This book was released on 2013-11-15 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes
Download or read book Molecular Neuropathology written by Gareth W. Roberts and published by Cambridge University Press. This book was released on 1995-06-08 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.
Download or read book The Epidemiology of Schizophrenia written by Robin M. Murray and published by Cambridge University Press. This book was released on 2009-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.
Download or read book Schizophrenia written by Neil A. Rector and published by Guilford Press. This book was released on 2011-03-01 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Aaron T. Beck and colleagues, this is the definitive work on the cognitive model of schizophrenia and its treatment. The volume integrates cognitive-behavioral and biological knowledge into a comprehensive conceptual framework. It examines the origins, development, and maintenance of key symptom areas: delusions, hallucinations, negative symptoms, and formal thought disorder. Treatment chapters then offer concrete guidance for addressing each type of symptom, complete with case examples and session outlines. Anyone who treats or studies serious mental illness will find a new level of understanding together with theoretically and empirically grounded clinical techniques.
Download or read book Schizophrenia written by Bojan Sterenborg and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Schizophrenia is a major psychiatric disorder characterized by a disruption in neuropsychological function that usually manifests itself between the age of 10 and 35. Schizophrenia: Advances in Research and Future Directions provides a broad overview of the domains, severity, and course of neuropsychological functioning in schizophrenia patients. Genetic variations and markers can serve as a diagnostic, prognostic and therapeutic tool for the patients. As such, the authors describe and summarize the blood-based biomarkers of schizophrenia from the diagnostic, prognostic and therapeutic points of view. The closing study aims to determine the role of internalized stigma in the presence and severity of fear of negative evaluation in patients with schizophrenia, specifically hypothesizing that a higher perceived discrimination will be the most important predictor"--
Download or read book Genomics Circuits and Pathways in Clinical Neuropsychiatry written by Thomas Lehner and published by Academic Press. This book was released on 2016-06-07 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. - Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics - Identifies key concepts, methods, and findings - Includes coverage of multiple disorders from autism to schizophrenia - Reviews specific genes associated with disorders - Discusses the genetic architecture of these syndromes - Explains how recent findings are influencing the understanding of biology - Clarifies the promise of these findings for future treatment
Download or read book Advances in Schizophrenia Research 2009 written by Wagner F. Gattaz and published by Springer. This book was released on 2014-09-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia remains an important challenge to psychiatry, with its causes and underlying brain mechanisms yet to be fully revealed. Currently available treatments are neither universally effective nor without unwanted effects. These aspects, together with the high prevalence of schizophrenia, its often debilitating nature, and the associated family and social burden, make this mental disorder one of the most complex public health issues of our times. The purpose of the Advances in Schizophrenia Research series is to provide comprehensive periodic reviews of the wide range of research studies carried out around the world, with the dual purpose of solving the schizophrenia puzzle, and providing clues to new forms of treatment and prevention for this disorder. A special feature of the series is its broad scope, virtually encompassing all fields of schizophrenia research: epidemiology and risk factors; psychopathology; diagnostic boundaries; cognition; outcome and prognosis; pathophysiology; genetics; pharmacological and psychological forms of treatment and rehabilitation; community care; and stigmatization.
Download or read book Cohort Studies in Health Sciences written by R. Mauricio Barría and published by Intechopen. This book was released on 2018 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introductory Chapter: The Contribution of Cohort Studies to Health Sciences.
Download or read book The Origins of Schizophrenia written by Alan S. Brown and published by Columbia University Press. This book was released on 2011-11-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Origins of Schizophrenia synthesizes key findings on a devastating mental disorder that has been increasingly studied over the past decade. Advances in epidemiology, translational neuroscience technology, and molecular and statistical genetics have recast schizophrenia's neurobiological nature, identifying new putative environmental risk factors and candidate susceptibility genes. Providing the latest clinical and neuroscience research developments in a comprehensive volume, this collection by world-renowned investigators answers a pressing need for balanced, thorough information, while pointing to future directions in research and interdisciplinary collaboration. The book, featuring a foreword by Robert Freedman, M.D., thoroughly examines these topics from the vantage points of epidemiologic, clinical, and basic neuroscience approaches, making it an essential resource for researchers in psychiatry, psychology, and neuroscience and for clinical mental health professionals.
Download or read book Neuroimaging in Schizophrenia written by Marek Kubicki and published by Springer Nature. This book was released on 2020-02-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Download or read book The Neurobiology of Schizophrenia written by Ted Abel and published by Academic Press. This book was released on 2016-07-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. - Provides a comprehensive overview of neurobiological aspects of schizophrenia - Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels - Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance - Elucidates connections between the various systems depicted, when possible
