Download or read book Rapid Identification of Narcotics Using Thin layer Chromatography in the Pharmaceutical Laboratory written by E Stahl and published by . This book was released on 1981 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Rapid Method of Thin Layer Chromatography to Aid the Identification of Quaternary Nitrogen Drugs written by H. D. Crone and published by . This book was released on 1972 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt: The quaternary nitrogen drugs present some problems when identifying them in a mixture of drugs or in tissues. This note describes a TLC (thin-layer chromatography) method by which microgram amounts of quaternary nitrogen drugs can be separated and tentatively identified in less than 30 min.
Download or read book Plant Drug Analysis written by Sabine Bladt and published by Springer Science & Business Media. This book was released on 2009-05-17 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Plant Drug Analysis includes more than 200 updated color photographs of superb quality demonstrating chromatograms of all relevant standard drugs. All drugs presented meet the standard of the official pharmacopoeia and originate from well-defined botanical sources. With this guide the technique of thin layer chromatography can be easily used without previous pharmacognostic training. Only commercially available equipment and reagents are needed, the sources as well as all practical details are given. From the reviews "...should not be missed in any laboratory dealing with crude drug analysis" trends in analytical chemistry "...a unique and remarkable collection...an invaluable guide" Phytochemistry "The color photographs...are unbelievably well done" Analytical Biochemistry "...a required text for any laboratory concerned with the analysis of medicinal plant products" Irish Pharmacy Journal
Download or read book Identification of Drugs in Pharmaceutical Formulations by Thin Layer Chromatography written by P. D. Sethi and published by . This book was released on 1992 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Countering the Problem of Falsified and Substandard Drugs written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adulteration and fraudulent manufacture of medicines is an old problem, vastly aggravated by modern manufacturing and trade. In the last decade, impotent antimicrobial drugs have compromised the treatment of many deadly diseases in poor countries. More recently, negligent production at a Massachusetts compounding pharmacy sickened hundreds of Americans. While the national drugs regulatory authority (hereafter, the regulatory authority) is responsible for the safety of a country's drug supply, no single country can entirely guarantee this today. The once common use of the term counterfeit to describe any drug that is not what it claims to be is at the heart of the argument. In a narrow, legal sense a counterfeit drug is one that infringes on a registered trademark. The lay meaning is much broader, including any drug made with intentional deceit. Some generic drug companies and civil society groups object to calling bad medicines counterfeit, seeing it as the deliberate conflation of public health and intellectual property concerns. Countering the Problem of Falsified and Substandard Drugs accepts the narrow meaning of counterfeit, and, because the nuances of trademark infringement must be dealt with by courts, case by case, the report does not discuss the problem of counterfeit medicines.
Download or read book Identification of Street Drugs by Thin Layer Chromatography and a Single Visualization Reagent written by JA. Vinson and published by . This book was released on 1975 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of reports on the use of thin-layer chromatography (TLC) in the analysis of street drugs have appeared [1-3]. Colors with various visualization agents applied in sequence are used for identification in conjunction with Rf values, spot tests [4], and crystal tests [5]. This paper reports the use of a rapid TLC screening procedure that utilizes a single developing solvent and a single visualization reagent, N,2,6-trichloro-p-benzoquinone imine (TCBI), for the preliminary identification of the drugs of abuse. In addition, other TLC developing solvents are outlined that can be used for further confirmation.
Download or read book Plant Drug Analysis written by Hildebert Wagner and published by . This book was released on 1984 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Drug Analysis has proven an invaluable and unique aid for all those involved with drug production and analysis, including pharmacists, chemical and pharmaceutical researchers and technicians, drug importers and exporters, governmental chemical control agencies, and health authorities. From the reviews of the German Edition: "The reviewer would like to recommend this excellent book to all chromatographers, as he considers it highly relevant to the solution of numerous problems. Its main purpose is the demonstration of thin-layer chromatograms of the usual commercial drugs as an aid in testing for identity and purity. ... 165 colour plates, each showing 6 chromatograms and all of superb quality photographs ..." (Journal of Chromatography).
Download or read book Screening for drugs and poisons by thin layer chromatography and fast black salt written by Ilkka Ojanperä and published by . This book was released on 1992 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantitative Thin Layer Chromatography written by Bernd Spangenberg and published by Springer Science & Business Media. This book was released on 2011-01-03 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thin-layer chromatography (TLC) is widely used particularly for pharmaceutical and food analysis. While there are a number of books on the qualitative identification of chemical substances by TLC, the unique focus here is on quantitative analysis. The authors describe all steps of the analytical procedure, beginning with the basics and equipment for quantitative TLC followed by sample pretreatment and sample application, development and staining, scanning, and finally statistical and chemometric data evaluation and validation. An important feature is the coverage of effect-directed biological detection methods. Chapters are organized in a modular fashion facilitating the easy location of information about individual procedural steps.
Download or read book Practical Thin Layer Chromatography written by Bernard Fried and published by CRC Press. This book was released on 2017-11-22 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Thin-Layer Chromatography provides thorough coverage of the principles, practices, and applications of thin-layer chromatography (TLC) for important sample and compound types. This information is directed specifically at workers in the most active scientific fields.
Download or read book Thin Layer Chromatography in Drug Analysis written by Lukasz Komsta and published by CRC Press. This book was released on 2013-12-20 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt: Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date, complete reference, Thin Layer Chromatography in Drug Analysis covers the most important methods in pharmaceutical applications of TLC, namely, analysis of bulk drug material and pharmaceutical formulations, degradation studies, analysis of biological samples, optimization of the separation of drug classes, and lipophilicity estimation. The book is divided into two parts. Part I is devoted to general topics related to TLC in the context of drug analysis, including the chemical basis of TLC, sample pleparation, the optimization of layers and mobile phases, detection and quantification, analysis of ionic compounds, and separation and analysis of chiral substances. The text addresses the newest advances in TLC instrumentation, two-dimensional TLC, quantification by slit scanning densitometry and image analysis, statistical processing of data, and various detection and identification methods. It also describes the use of TLC for solving a key issue in the drug market—the presence of substandard and counterfeit pharmaceutical products. Part II provides an in-depth overview of a wide range of TLC applications for separation and analysis of particular drug groups. Each chapter contains an introduction about the structures and medicinal actions of the described substances and a literature review of their TLC analysis. A useful resource for chromatographers, pharmacists, analytical chemists, students, and R&D, clinical, and forensic laboratories, this book can be utilized as a manual, reference, and teaching source.
Download or read book Chemical Criminalistics written by A. Maehly and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a number of textbooks on forensic science have been published, most of them directed to two groups, viz. the students of forensic science, and the customers so to say, (prosecutors, police officers, judges, defense lawyers). In this book, while covering fundamental concepts, we try to go a little further and address also active workers in the field of forensic chemistry. This is mainly achieved by relatively nu merous literature references. We hope that they may assist the forensic chemist in penetrating further into the subjects covered in this volume. At the end of most chapters there are examples of actual cases handled at the Swedish National Laboratory of Forensic Science. Many of these cases could, no doubt, have been investigated in greater detail, but they reflect the compromises often necessary for achieving a reasonable turnover. Some parts of the book are quite strongly colored by the personal opinions of the authors. We felt that these passages will give a little more life to the text than in other treatises of a more objective, but possibly duller character. The authors welcome all constructive criticism which will help to improve the book, should there be a second edition.
Download or read book Drug Abuse Handbook written by Steven B. Karch, MD, FFFLM and published by CRC Press. This book was released on 2019-07-17 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the handbook that professionals who deal with problems related to drugs and drug abuse have been waiting for. The impressive list of more than 80 contributors, each experts and leaders in their field, testifies to the importance of this outstanding new handbook. The volume contains detailed discussions of drug-related issues in criminalistics, pathology, and toxicology. Impairment testing and the pharmacokinetics of abused drugs are examined in detail, as is the field of workplace drug testing, the use of alternate testing matrices, drugs in sports, addiction medicine, and drug-related medical emergencies. The handbook focuses on the most urgent drug abuse-related problems of today An entire section is devoted to alcohol abuse, including a scientific appraisal of the most common drunk driving defenses, complete with sample calculations. Problems of postmortem toxicology are thoroughly detailed and an appendix lists key references for the most widely used analytic methods. An in-depth analysis of legal questions, including fetal rights and workplace testing Examination of the principles of addiction medicine and how doctors handle substance abuse problems A section addressing drug use by athletes, including a summary of current Olympic Committee Regulations regarding substance use and the latest information on detecting abuse of Human Growth Hormone and Erythropoietin Whether you are approaching the issue of drug abuse from a medical, psychological, toxicological, or legal perspective, the Drug Abuse Handbook is the most authoritative and complete resource available.
Download or read book Analysis of Sterols and Other Biologically Significant Steroids written by W. David Nes and published by Elsevier. This book was released on 2012-12-02 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Sterols and Other Biologically Significant Steroids provides the fundamental training for the analysis of selected sterols and steroids. The book is composed of chapters that review the spectroscopic and chromatographic properties of certain sterols and steroids. The text also teaches how to isolate and characterize sterols and steroid metabolites of plant, fungal, and insect origin. Lipoprotein analysis and the utilization of physical-analytical techniques are likewise provided. Biochemists, microbiologists, and medical physiologists will find the book useful.
Download or read book Handbook of Secondary Fungal Metabolites written by Richard J. Cole and published by Gulf Professional Publishing. This book was released on 2003 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set is a desirable reference for a wide range of specialists who study secondary fungal metabolites ranging from pharmaceutical house researchers, agricultural researchers, those involved in food and feed control regulation, and veterinary researchers. It discusses in depth the molecular formula of, the molecular weights of, and fungal/plant source indexes of secondary fungal metabolites.
Download or read book The Biology of Cholesterol and Related Steroids written by N. B. Myant and published by Butterworth-Heinemann. This book was released on 2014-04-24 with total page 925 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Cholesterol and Related Steroids focuses on the study of sterols in relation to living organisms. The publication first takes a look at the analysis of sterols and related steroids and the distribution of sterols and related steroids in nature, as well as the processes of extraction and separation and presence of sterols in plants, fungi, vertebrates, and invertebrates. The text then ponders on biosynthesis of sterols and metabolism of cholesterol. Topics include formation of fatty acid esters of cholesterol, steroid hormones, biosynthetic pathway to sterols, reaction mechanisms, and comparative aspects of sterol synthesis. The manuscript examines the developmental aspects of cholesterol metabolism and sterols in biological membranes. The book also reviews cholesterol synthesis in animal tissues, sterol metabolism in isolated cells, and epidemiology of the plasma cholesterol. Discussions focus on selection of statistical populations, genetic influences, regulation of sterol synthesis, general aspects of sterol metabolism, and removal of cell cholesterol in vivo. The publication is a dependable source of data for biochemists and readers interested in the biology of cholesterol and steroids.
Download or read book Thin Layer Chromatography written by Egon Stahl and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thin-layer chromatography has become so widely known in the space of a few years that it has proved necessary to gather into book form and thus make generally accessible the experimental material previously only available in isolated publications. As thin-layer chromatography can be used both for organic and inorganic matter as well as on quantities ranging from the nanogram to the microgram, it is impossible for anyone individual to possess sufficient laboratory experience or overall knowledge to produce a practical handbook that will be of real assistance to be ginner and specialist alike. For this reason, an international group was formed, who made it their task to produce the best possible treatise. In view of the present stage of development reached by thin-Iaycr chromatography, it seems specially apt that the authors should include yet unpublished work of their own. As thin-layer chromatography is used in many different fields in natural science and medicine, the kind of brief description of materials intelligible only to the expert has been avoided. The short guides to the chemical properties of the groups to be separated, their names, and relevant bibliographic details should facilitate introductory studies arid make possible a close acquaintance with the material in hand. It also seemed advisable to give brief details of the analytical classification of material, which is so often necessary. Although the classification used may appear unusual, it is in fact pre-eminently suitable to thin-layer chromatography.
