Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Download or read book Radionuclides in Biomedical Sciences written by Chandrani Liyanage and published by Foundation Books. This book was released on 2008-11 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radionuclide-based microanalytical techniques such as RIA & IRMA are among the most widely used techniques for medical diagnosis and research. Radionuclides in Biomedical Science provides details of the key concepts of this area.
Download or read book Isotopes for Medicine and the Life Sciences written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-27 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.
Download or read book Life Atomic written by Angela N. H. Creager and published by University of Chicago Press. This book was released on 2013-10-02 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government’s attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation. Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC’s provision of radioisotopes for research and medicine.
Download or read book The Supply of Medical Isotopes written by and published by . This book was released on 2019 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.
Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.
Download or read book Radiation in Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1996-03-25 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does radiation medicine need more regulation or simply better-coordinated regulation? This book addresses this and other questions of critical importance to public health and safety. The issues involved are high on the nation's agenda: the impact of radiation on public safety, the balance between federal and state authority, and the cost-benefit ratio of regulation. Although incidents of misadministration are rare, a case in Pennsylvania resulting in the death of a patient and the inadvertent exposure of others to a high dose of radiation drew attention to issues concerning the regulation of ionizing radiation in medicine and the need to examine current regulatory practices. Written at the request from the Nuclear Regulatory Commission (NRC), Radiation in Medicine reviews the regulation of ionizing radiation in medicine, focusing on the NRC's Medical Use Program, which governs the use of reactor-generated byproduct materials. The committee recommends immediate action on enforcement and provides longer term proposals for reform of the regulatory system. The volume covers: Sources of radiation and their use in medicine. Levels of risk to patients, workers, and the public. Current roles of the Nuclear Regulatory Commission, other federal agencies, and states. Criticisms from the regulated community. The committee explores alternative regulatory structures for radiation medicine and explains the rationale for the option it recommends in this volume. Based on extensive research, input from the regulated community, and the collaborative efforts of experts from a range of disciplines, Radiation in Medicine will be an important resource for federal and state policymakers and regulators, health professionals involved in radiation treatment, developers and producers of radiation equipment, insurance providers, and concerned laypersons.
Download or read book Physics in Nuclear Medicine written by Simon R. Cherry and published by . This book was released on 2003 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, the authors provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labelled tracers. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.
Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Download or read book Handbook of Radiopharmaceuticals written by Michael J. Welch and published by John Wiley & Sons. This book was released on 2003-01-17 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Download or read book Health Risks of Radon and Other Internally Deposited Alpha Emitters written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Download or read book Nuclear Medicine Therapy written by Janet F. Eary and published by CRC Press. This book was released on 2007-03-30 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources. Serving as a complete literature reference for therapy with radiopharmaceuticals c
Download or read book Environmental Radioactivity and Emergency Preparedness written by Mats Isaksson and published by CRC Press. This book was released on 2017-01-06 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive sources such as nuclear power installations can pose a great threat to both humans and our environment. How do we measure, model and regulate such threats? Environmental Radioactivity and Emergency Preparedness addresses these topical questions and aims to plug the gap in the lack of comprehensive literature in this field. The book explores how to deal with the threats posed by different radiological sources, including those that are lost or hidden, and the issues posed by the use of such sources. It presents measurement methods and approaches to model and quantify the extent of threat, and also presents strategies for emergency preparedness, such as strategies for first-responders and radiological triage in case an accident should happen. Containing the latest recommendations and procedures from bodies such as the IAEA, this book is an essential reference for both students and academicians studying radiation safety, as well as for radiation protection experts in public bodies or in the industry.
Download or read book Cyclotron Produced Radionuclides written by and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.
Download or read book Radiological Sciences Dictionary Keywords names and definitions written by David Dowsett and published by CRC Press. This book was released on 2009-03-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Radiological Sciences Dictionary is a rapid reference guide for all hospital staff employed in diagnostic imaging, providing definitions of over 3000 keywords as applied to the technology of diagnostic radiology.Written in a concise and easy to digest form, the dictionary covers a wide variety of subject matter, including:a radiation legislati
Download or read book The Essential Physics of Medical Imaging written by Jerrold T. Bushberg and published by Lippincott Williams & Wilkins. This book was released on 2011-12-28 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: This renowned work is derived from the authors' acclaimed national review course (“Physics of Medical Imaging") at the University of California-Davis for radiology residents. The text is a guide to the fundamental principles of medical imaging physics, radiation protection and radiation biology, with complex topics presented in the clear and concise manner and style for which these authors are known. Coverage includes the production, characteristics and interactions of ionizing radiation used in medical imaging and the imaging modalities in which they are used, including radiography, mammography, fluoroscopy, computed tomography and nuclear medicine. Special attention is paid to optimizing patient dose in each of these modalities. Sections of the book address topics common to all forms of diagnostic imaging, including image quality and medical informatics as well as the non-ionizing medical imaging modalities of MRI and ultrasound. The basic science important to nuclear imaging, including the nature and production of radioactivity, internal dosimetry and radiation detection and measurement, are presented clearly and concisely. Current concepts in the fields of radiation biology and radiation protection relevant to medical imaging, and a number of helpful appendices complete this comprehensive textbook. The text is enhanced by numerous full color charts, tables, images and superb illustrations that reinforce central concepts. The book is ideal for medical imaging professionals, and teachers and students in medical physics and biomedical engineering. Radiology residents will find this text especially useful in bolstering their understanding of imaging physics and related topics prior to board exams.
