Download or read book Radiomics in Gastric Cancer written by Bo Zhang and published by Frontiers Media SA. This book was released on 2023-12-28 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer (GC) is one of the most common malignancies worldwide. It is particularly challenging due to common detection at the advanced stages of the diseases preventing potential therapeutic and treatment strategies for patients. Common forms of treatment include chemotherapy which has been found to improve the survival rate and overall quality of life for patients with unresectable, locally advanced or at the metastatic stages of the disease. However, chemotherapy has also proven to cause significant side effects in some patients. Lymphatic metastasis has been found to be common in gastric cancer patients. Lymph vascular invasion (LVI) has been identified to be associated to the infiltration of tumor cells in the arteries, veins or lymphatic vessels. This has been identified to prompt local recurrence and the distant metastasis of various tumors. This has led to the LVI status as an independent prognostic factor and studies have found the occurrence of pathological LVI is associated with gastric cancer progression and linked to poor clinical prognosis and low survival rate.

Download or read book Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers written by Pallaval Veera Bramhachari and published by Springer Nature. This book was released on 2020-07-21 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancer treatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.

Download or read book Radiologic Diagnosis of Gastric Cancer written by L.M. Portnoy and published by Springer Science & Business Media. This book was released on 2006-05-05 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: L.M. Portnoy is one of Russia's leading radiologists. This book is the result of his more than 30 years' experience in the field of cancer diagnosis. The author reviews for us the potentials – currently greatly underestimated – of radiological examination and the traditional X-ray for the diagnosis of gastric cancer. This comprehensive overview of methodological approaches to the X-ray examination of the stomach and corrected tumor semiotics will help practicing physicians and residents to diagnose even the most minuscule tumors. Portnoy covers all diagnostic methods related to abdominal cancer, with thorough explanations of the methodological, semiotic, and organizational aspects. This work by one of the best-known Russian specialists in X-ray diagnosis will be of interest not only for all those who want to know more about the history of radiology as a profession, but also for students, who can study the tips and tricks of a master.

Download or read book Gastric Cancer written by Mitsumasa Nishi and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer is still the most common cause of cancer death in the world, although in most countries, with the notable exception of the United States, its incidence is slowly declining. In statistical terms, gastric cancer is therefore the most formidable of cancer types, and its control is a pressing issue. Recent evidence indicates that the conversion of normal cells to so-called "clinical cancer" is the prerequisite for a multistage process which is intimately associated with an accumulation of multiple gene alterations including both oncogenes and tumor-suppressor genes. Gastric cancer is no exception, in that it reveals multiple gene changes whose scenario differs, depending on their occurrence in intestinal-type or diffuse-type gastric cancers. This book was planned for publication by the Japanese Research Society for Gastric Cancer in order to shed light on basic research and clinical practice in gastric cancer. The individual chapters, written by a variety of experts, contain numerous new topics related to all aspects of the disease, including epidemiology, experimental carcinogenesis, pathology, biology, diagnosis, and treatment. It is hoped that this book will be of use in basic research, pathological diagnosis, early detection, and therapy of gastric cancer. We would like to thank the staff of Springer-Verlag Tokyo for the excellent technical production.

Download or read book Gastric Cancer written by Vivian E. Strong and published by Springer. This book was released on 2015-06-10 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it’s management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.

Download or read book Emerging Diagnostic and Therapeutic Approaches for Gastric Cancer written by Lin Chen and published by Frontiers Media SA. This book was released on 2020-12-31 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Download or read book Gastric Cancer In The Precision Medicine Era written by Vincenzo Canzonieri and published by Springer. This book was released on 2019-05-02 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries. In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies. The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer. The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section. With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer has been delineated and molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified. These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section. The text will conclude with chapters focusing on the future direction of gastric cancer research in the precision medicine era: an in-depth analysis of non-coding RNAs and their role in gastric cancer, the impact of immunomodulation/immunotherapy and the perspectives of nano-medicine will be finally proposed to the audience. A brief review of the existing literature addressing the above mentioned topics will be present in each chapter. This text will serve as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

Download or read book Computer Age Statistical Inference written by Bradley Efron and published by Cambridge University Press. This book was released on 2016-07-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and in influence. 'Big data', 'data science', and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? This book takes us on an exhilarating journey through the revolution in data analysis following the introduction of electronic computation in the 1950s. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. The book ends with speculation on the future direction of statistics and data science.

Download or read book Gastric Cancer Research Trends written by Marilyn B. Tompkins and published by Nova Publishers. This book was released on 2007 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stomach cancer (also called gastric cancer) is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2 percent (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables.Infection with H. pylori is the main risk factor in about 80 percent or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90 percent of individuals with stomach cancer, with a five year survival rate of 75 percent in those diagnosed in early stages and less than 30 percent of those diagnosed in late stages. This book presents new and important research from around the world.

Download or read book Radiomics and Radiogenomics written by Ruijiang Li and published by CRC Press. This book was released on 2019-07-09 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Download or read book Management of Gastric Cancer written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Download or read book Research Focus on Gastric Cancer written by Dorothy C. Cardinni and published by Nova Publishers. This book was released on 2008 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important leading-edge research on stomach cancer. Stomach cancer (also called "gastric cancer") is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2% (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables. Infection with H. pylori is the main risk factor in about 80% or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in early stages and less than 30% of those diagnosed in late stages.

Download or read book The Diversity of Gastric Carcinoma written by M. Kaminishi and published by Springer Science & Business Media. This book was released on 2006-03-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: • Japan is a leader in screening for and treating gastric cancer - this title first publishes Japan’s newest research in English • Contributors are internationally recognized specialists with publications on gastrointestinal cancers in many high ranking medical journals from Europe and the USA • Michio Kaminishi was president of the 3rd International Conference of the ISGC

Download or read book Gastric Cancer written by Hajime Orita and published by . This book was released on 2019 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, Gastric Cancer - An Update, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of gastric cancer. The book is comprised of single chapters authored by various researchers and it is edited by experts active in this field of study. All chapters are complete in itself but united under a common research topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on gastric cancer, and opening new possible research paths for further novel developments.

Download or read book New Developments in the Management of Gastric Cancer written by P. Malfertheiner and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The overall prognosis for patients with gastric cancer remains poor as tumors are often diagnosed at an advanced stage, despite new developments and technical advances in endoscopic diagnosis and therapy. This publication brings together leading experts in the fields of basic research and clinical management of gastric cancer, to share their expertise with the clinical community. State-of-the-art reviews discuss the pathogenesis of and the most important risk factors for the development of gastric cancer, potential benefits of chemoprevention and Helicobacter pylori eradication. Moreover, new diagnostic modalities and surgical therapy, including the potential benefits of neoadjuvant and adjuvant therapies, are presented. As most patients require palliative therapy because of locally advanced or metastasized cancers, several reviews are dedicated to advances in the chemotherapy of advanced gastric cancers and peritoneal metastasis. Finally, future approaches towards a molecular diagnosis and therapy are described. Those involved in the management of gastric cancer patients will find the information presented in this publication of utmost help and will benefit greatly for their daily routine.

Download or read book Staging Laparoscopy written by P. Hohenberger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Download or read book Machine Learning Models and Algorithms for Big Data Classification written by Shan Suthaharan and published by Springer. This book was released on 2015-10-20 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents machine learning models and algorithms to address big data classification problems. Existing machine learning techniques like the decision tree (a hierarchical approach), random forest (an ensemble hierarchical approach), and deep learning (a layered approach) are highly suitable for the system that can handle such problems. This book helps readers, especially students and newcomers to the field of big data and machine learning, to gain a quick understanding of the techniques and technologies; therefore, the theory, examples, and programs (Matlab and R) presented in this book have been simplified, hardcoded, repeated, or spaced for improvements. They provide vehicles to test and understand the complicated concepts of various topics in the field. It is expected that the readers adopt these programs to experiment with the examples, and then modify or write their own programs toward advancing their knowledge for solving more complex and challenging problems. The presentation format of this book focuses on simplicity, readability, and dependability so that both undergraduate and graduate students as well as new researchers, developers, and practitioners in this field can easily trust and grasp the concepts, and learn them effectively. It has been written to reduce the mathematical complexity and help the vast majority of readers to understand the topics and get interested in the field. This book consists of four parts, with the total of 14 chapters. The first part mainly focuses on the topics that are needed to help analyze and understand data and big data. The second part covers the topics that can explain the systems required for processing big data. The third part presents the topics required to understand and select machine learning techniques to classify big data. Finally, the fourth part concentrates on the topics that explain the scaling-up machine learning, an important solution for modern big data problems.