Download or read book Quantitative Ultrasound Imaging Using Acoustic Backscatter Coefficients written by Evan Jeffery Boote and published by . This book was released on 1988 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantitative Ultrasound written by Zara Vajihi and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the main limitations of ultrasound imaging is that image quality and interpretation depend on the skill of the user and the experience of the clinician. Quantitative ultrasound (QUS) methods provide objective, system-independent estimates of tissue properties such as acoustic attenuation and backscattering properties of tissue, which are valuable as objective tools for both diagnosis and intervention. Accurate and precise estimation of these properties requires correct compensation for intervening tissue attenuation. Prior attempts to estimate intervening-tissues attenuation based on minimizing cost functions that compared backscattered echo data to models have resulted in limited precision and accuracy. The first contribution of this thesis is that we incorporate the prior information of piece-wise continuity of QUS parameters as an L2 norm regularization term into our cost function to overcome these limitations. We further propose to calculate this cost function using Dynamic Programming (DP), a computationally efficient optimization algorithm that finds the global optimum. Our results on tissue-mimicking phantoms show that DP substantially outperforms a state-of-the-art method in terms of both estimation bias and variance. The second contribution of this thesis is that to further improve the accuracy and precision of this DP method, we propose to use L1 norm instead of L2 norm as the regularization term in our cost function and optimize the function using DP. Our results show that DP with L1 regularization reduces bias of attenuation and backscatter parameters even further compared to DP with L2 norm. Besides, we employ DP to estimate the QUS parameters of a new phantom with large scatterer size and compare the results of LSq, L2 norm DP and L1 norm DP. Our results show that L1 norm DP outperforms L2 norm DP, which itself outperforms LSq. In the future, the contributions of this thesis can potentially be used for finding imaging biomarkers associated with different types of pathology and help clinicians obtain an objective assessment of intrinsic tissue properties.
Download or read book Quantitative Ultrasound in Soft Tissues written by Jonathan Mamou and published by Springer Science & Business Media. This book was released on 2013-09-26 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to parallel advances in signal processing and computer hardware in the last 15 years, quantitative ultrasound techniques have reached maturity, allowing for the construction of quantitative maps or images of soft tissues. This book will focus on 5 modern research topics related to quantitative ultrasound of soft tissues: - Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc.; - Envelope statistics analysis as a means of quantifying and imaging tissue properties; - Ultrasound elastography for quantifying elastic properties of tissues (several clinical ultrasound scanners now display elastography images); - Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution (desktop size scanners are now available); and - Ultrasound computer tomography for breast cancer imaging (new ultrasound tomography systems have been developed and are currently under evaluation clinically).
Download or read book New Developments on Quantitative Imaging Using Ultrasonic Waves written by and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultrasonic Scattering in Biological Tissues written by K. Kirk Shung and published by CRC Press. This book was released on 2022-09-16 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasonic Scattering in Biological Tissues contains 14 chapters written by world-renowned authorities who describe current work related to theoretical and experimental aspects of ultrasonic scattering phenomenon in biological tissues. Introductory material regarding ultrasonic scattering in biological tissues is presented, followed by discussions on theoretical treatments, experimental approaches, in vitro results on selective tissues, in vivo results on various tissues, and the current status of quantitative backscatter imaging. Ultrasonic Scattering in Biological Tissues will be an excellent reference for biomedical engineers, ultrasound specialists, biophysicists, and radiology researchers.
Download or read book In Vivo Quantitative Ultrasound Imaging and Scatter Assessments written by Zheng Feng Lu and published by . This book was released on 1994 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultrasonic Scattering in Biological Tissues written by K. Kirk Shung and published by CRC Press. This book was released on 1992-12-18 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasonic Scattering in Biological Tissues contains 14 chapters written by world-renowned authorities who describe current work related to theoretical and experimental aspects of ultrasonic scattering phenomenon in biological tissues. Introductory material regarding ultrasonic scattering in biological tissues is presented, followed by discussions on theoretical treatments, experimental approaches, in vitro results on selective tissues, in vivo results on various tissues, and the current status of quantitative backscatter imaging. Ultrasonic Scattering in Biological Tissues will be an excellent reference for biomedical engineers, ultrasound specialists, biophysicists, and radiology researchers.
Download or read book Quantitative Ultrasound Imaging During Ablation Procedures written by Kayvan Samimi and published by . This book was released on 2017 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional ultrasound imaging (i.e. B-mode sonogram) is a qualitative mode of imaging based on visualizing the relative echogenicity of different tissue types within the body. This useful mode of imaging has aided clinicians for more than 50 years. However, B-mode imaging does not capture any of the frequency-dependent information that is contained within the ultrasound echo signal. Additionally, due to its qualitative nature, there is much inter-system and inter-observer variability with regard to generation and interpretation of B-mode images. Quantitative Ultrasound (QUS) methods have been developed to extract additional information by estimating acoustic properties of tissue from the frequency-domain representation of echo signals. These estimates can be converted to color-coded maps that are visualized along with conventional B-mode images to form enhanced ultrasound images. Such images can potentially provide valuable diagnostic and prognostic information to medical professionals. Some of the more important acoustic parameters of interest in QUS and tissue characterization are the ultrasonic attenuation coefficient and the backscatter coefficient. Attenuation has been studied as a potential classifier of normal and pathological liver tissue. In addition to providing pathological information for diagnosis, monitoring these QUS parameters during therapeutic procedures such as tumor ablation can lead to targeted and optimized treatment. The goals of this dissertation are to theoretically model and analyze current methods of acoustic attenuation estimation; improve attenuation estimation algorithms to enhance the quality of subsequent QUS images; and correlate changes in QUS parameter values with progression of thermally ablative procedures for ex-vivo and in-vivo liver ablations. Although QUS imaging may be used to assist clinicians in various stages of diagnosis and treatment of diseases in a multitude of bodily organs and tissue types, this dissertation focuses on thermal ablation of primary or metastatic liver tumors in order to showcase the possible benefits of the proposed estimation methods and to compare their performance with existing estimation techniques. Additionally, simulated and physical tissue-mimicking (TM) phantoms with known acoustic properties are used to statistically test and compare the accuracy and precision of these methods. Theoretical analysis and experimental results suggest that our proposed method for estimation of the ultrasonic attenuation coefficient based on measurement of frequency shifts in a normalized power-spectral representation of the ultrasonic echo signal is best suited to in-vivo QUS imaging in clinical settings and provides estimates with standard deviations that are at least three times smaller than was previously possible with other methods.
Download or read book Quantitative Ultrasound in Soft Tissues written by Jonathan Mamou and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative ultrasound (QUS) continues to mature as a research field and is primed to make a swift transition to routine preclinical and clinical applications. This book will serve two main purposes: Advanced education in QUS by providing a complete and thorough review of all theoretical, physical, and engineering aspects of QUS. Review of recent development of QUS by lead contributors in the research field. This 2nd edition will focus on 6 modern research topics related to quantitative ultrasound of soft tissues: Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc. Attenuation estimation for tissue characterization and improving spectral based methods Envelope statistics analysis as a means of quantifying and imaging tissue properties. Ultrasound computed tomography for preclinical and clinical imaging. Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution. Phantoms for quantitative ultrasound.
Download or read book Quantitative Ultrasound in Soft Tissues written by Jonathan Mamou and published by Springer Nature. This book was released on 2023-07-26 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative ultrasound (QUS) continues to mature as a research field and is primed to make a swift transition to routine preclinical and clinical applications. This book will serve two main purposes: Advanced education in QUS by providing a complete and thorough review of all theoretical, physical, and engineering aspects of QUS. Review of recent development of QUS by lead contributors in the research field. This 2nd edition will focus on 6 modern research topics related to quantitative ultrasound of soft tissues: Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc. Attenuation estimation for tissue characterization and improving spectral based methods Envelope statistics analysis as a means of quantifying and imaging tissue properties. Ultrasound computed tomography for preclinical and clinical imaging. Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution. Phantoms for quantitative ultrasound.
Download or read book Bone Quantitative Ultrasound written by Pascal Laugier and published by Springer Science & Business Media. This book was released on 2010-11-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative ultrasound (QUS) of bone is a relatively recent research field. The research community is steadily growing, with interdisciplinary branches in acoustics, medical imaging, biomechanics, biomedical engineering, applied mathematics, bone biology and clinical sciences, resulting in significant achievements in new ultrasound technologies to measure bone, as well as models to elucidate the interaction and the propagation of ultrasonic wave in complex bone structures. Hundreds of articles published in specialists journals are accessible from the Web and from electronic libraries. However, no compilation and synthesis of the most recent and significant research exist. The only book on QUS of bone has been published in 1999 at a time when the propagation mechanisms of ultrasound in bone were still largely unknown and the technology was immature. The research community has now reached a critical size, special sessions are organized in major international meetings (e.g., at the World Congress of Biomechanics, the annual meetings of the Acoustical Society of America, International Bone Densitometry Workshop, etc...). Consequently, the time has come for a completely up to date, comprehensive review of the topic. The book will offer the most recent experimental results and theoretical concepts developed so far and is intended for researchers, graduate or undergraduate students, engineers, and clinicians who are involved in the field. The central part of the book covers the physics of ultrasound propagation in bone. Our goal is to give the reader an extensive view of the mathematical and numerical models as an aid to understand the QUS potential and the types of variables that can be determined by QUS in order to characterize bone strength. The propagation of sound in bone is still subject of intensive research. Different models have been proposed (for example, the Biot theory of poroelasticity and the theory of scattering have been used to describe wave propagation in cancellous bone, whereas propagation in cortical bone falls in the scope of guided waves theories). An extensive review of the models has not been published so far. We intend in this book to present in details the models that are used to solve the direct problem and strategies that are currently developed to address the inverse problem. This will include analytical theories and numerical approaches that have grown exponentially in recent years. Most recent experimental findings and technological developments will also be comprehensively reviewed.
Download or read book Quantitative Ultrasound written by Thomas Fuerst PhD and published by CRC Press. This book was released on 1999-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound is quickly becoming the technique of choice in the measurement of bone density. Proving cheaper and more portable than previous techniques, and also having the advantage of not using ionizing radiation, it is likely that the use of various ultrasound systems will become increasingly widespread in clinical practice. This book is a comprehensive review of the systems currently available, preceded by a summary of the basic science of ultrasound and concluding with a section on clinical studies, trials and experience in a number of countries. Likely future developments are also discussed, bringing the book completely up to date.
Download or read book Quantitative Ultrasound Techniques to Characterize Soft Tissue Anisotropy written by Lenin Chinchilla and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative ultrasound techniques based on the parameterization of the backscatter coefficient (BSC) generally assume that the tissue under investigation is homogeneous and isotropic. However, some tissues such as flowing red blood cell (RBC) aggregates, myocardium or bicep muscles exhibit angle-dependent acoustic properties (BSC and/or attenuation coefficient). The objective of this thesis was to incorporate anisotropy in tissue backscatter analysis. First, an ultrasonic backscattering model is proposed and evaluated numerically to characterize the anisotropic structures of RBC aggregates. Then, an experimental procedure was evaluated to measure BSC anisotropy in tissue-mimicking phantoms. More specifically, a performance comparison is carried out between a capacitive micromachined ultrasonic transducer probe and a commercial piezoelectric probe to measure backscatter anisotropy by using the focused beam steering imaging strategy.
Download or read book Ultrasonic Scattering in Biological Tissues written by K. Kirk Shung and published by CRC Press. This book was released on 2022-09-16 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasonic Scattering in Biological Tissues contains 14 chapters written by world-renowned authorities who describe current work related to theoretical and experimental aspects of ultrasonic scattering phenomenon in biological tissues. Introductory material regarding ultrasonic scattering in biological tissues is presented, followed by discussions on theoretical treatments, experimental approaches, in vitro results on selective tissues, in vivo results on various tissues, and the current status of quantitative backscatter imaging. Ultrasonic Scattering in Biological Tissues will be an excellent reference for biomedical engineers, ultrasound specialists, biophysicists, and radiology researchers.
Download or read book Quantitative Ultrasound Imaging of in Vivo Breast Tumors written by and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main goal of this dissertation is to perform quantitative ultrasound imaging (QUS) of in vivo breast tumors in order to provide new tools to differentiate benign from malignant breast masses. The studies outlined in Chapters 3-4 demonstrate that attenuation and backscatter coefficients (BSC) of phantoms can be estimated from the radiofrequency echo data acquired by a clinical ultrasound imaging system, when a well-calibrated reference phantom is used to account for dependencies of echo signals on system settings and transducer properties. Chapter 5 presents attenuation and backscatter coefficients for an animal breast tumor model and demonstrates the feasibility of producing accurate QUS parameters regardless of imaging system used. The study in Chapter 5 was validated in Chapter 6 using a phantom that mimics scanning conditions encountered in the animal model study. A least squares method (LSM) was introduced to estimate attenuation over inhomogeneous paths between an ultrasound transducer and a mass and was verified using phantoms. The LSM was also applied in QUS studies of human breast masses. Preliminary data on attenuation, BSCs, and effective scatterer diameters (ESD) within human breast masses were derived from a subject population undergoing breast biopsies. The attenuation in the mass was estimated from the product of the attenuation coefficient and antero-posterior dimension and was compared to relative acoustic shadowing criteria reported as "posterior echo features" in the BI-RADS lexicon. The BSC averaged over frequency (ABSC) provides information of the echogenicity of an object. The ABSC was compared to the "echo pattern" descriptor of the BI-RADS and showed a potential to quantify the echogenicity within masses. A plot of the ABSC and attenuation coefficient showed potential to differentiate between fibroadenomas and carcinomas with a linear discriminant. In addition, most fibroadenomas exhibited a wider distribution of ESD estimates over the ROI than carcinomas. Chapter 9 presents an assessment of accuracy of attenuation measurements by the reference phantom method when the tissue sound speed differs from that of the reference. These results demonstrate that a great progress has been made in the effort to develop QUS technology to improve breast ultrasound specificity
Download or read book Acoustical Imaging written by Roman Gr. Maev and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the Proceedings of the 26th Symposium on Acoustical Imaging held inWindsor, Ontario, Canada during September 9-12, 2001. This traditional scientific event is recognized as a premier forum for the presentation of advanced research results in both theoretical and experimental development. The lAIS was conceived at a 1967Acoustical Holography meeting in the USA. Since then, these traditional symposia provide an opportunity for specialists who are working in this area to make new acquaintances, renew old friendships and present recent results of their research. Our Symposium has grown significantly in size due to a broad interest in various topics and to the quality of the presentations. For the firsttime in 40 years, the IAIS was held in the province of Ontario in Windsor, Canada's Automotive Capital and City of Roses. The 26th IAIS attracted over 100specialists from 13countries representing this interdisciplinary field in physical acoustics, image processing, applied mathematics, solid-state physics, biology and medicine, industrial applications and quality control technologies. The 26th lAIS was organized in the traditional way with only one addition-a Special Session "History of Acoustical Imaging" with the involvement of such well known scientists as Andrew Briggs, Noriyoshi Chubachi, Robert Green Jr., Joie Jones, Kenneth Erikson, and Bernhard Tittmann. Many of these speakers are well known scientists in their fields and we would like to thank them for making this session extremely successful.
Download or read book Bone Quantitative Ultrasound written by Pascal Laugier and published by Springer Nature. This book was released on 2022-05-05 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many significant achievements in new ultrasound technologies to measure bone and models to elucidate the interaction and the propagation of ultrasonic waves in complex bone structures have been reported over the past ten years. Impaired bone remodeling affects not only the trabecular compartment but also the cortical one. Despite the crucial contribution of the cortical structure to the whole bone mechanical competence, cortical bone was understudied for a long time. A paradigm shift occurred around 2010, with a special focus placed on the importance of cortical bone. This has sparkled a great deal of interest in new ultrasound techniques to assess cortical bone. While our book ‘Bone Quantitative Ultrasound’ published in 2011 emphasized techniques to measure trabecular bone, this new book is devoted for a large part to the technologies introduced recently to measure cortical bone. These include resonant ultrasound spectroscopy, guided waves, scattering, and pulse-echo and tomography imaging techniques. Instrumentation, signal processing techniques and models used are detailed. Importantly, the data accumulated in recent years such as anisotropic stiffness, elastic engineering moduli, compression and shear wave speeds of cortical bones from various skeletal sites are presented comprehensively. A few chapters deal with the recent developments achieved in quantitative ultrasound of trabecular bone. These include (i) scattering-based approaches and their application to measure skeletal sites such as the spine and proximal femur and (ii) approaches exploiting the poro-elastic nature of bone. While bone fragility and osteoporosis are still the main motivation for developing bone QUS, this Book also includes chapters reporting ultrasound techniques developed for other applications of high interest such as 3-D imaging of the spine, assessment of implant stability and transcranial brain imaging. This book, together with the book ‘Bone Quantitative Ultrasound’ published in 2011 will provide a comprehensive overview of the methods and principles used in bone quantitative ultrasound and will be a benchmark for all novice or experienced researchers in the field. The book will offer recent experimental results and theoretical concepts developed so far and would be intended for researchers, graduate or undergraduate students, engineers, and clinicians who are involved in the field. The book should be considered as a complement to the first book publisher in 2011, rather than a second edition, in the sense that basic notions already presented in the first book are not repeated.