Download or read book QSAR in Environmental Toxicology written by K.L. Kaiser and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since Rachel Carson's Silent Spring, we have generally become aware of environmental contaminants and their effects on the ecosystem. The findin~ of PCB's in fish by Soren Jensen in Sweden, the recognition of mirex as contaminant in fish from Lake Ontario, and the discoveries of contaminant laden leachates from dumpsites such as the Love Canal have become milestones in the search for and charac terization of contaminants in our environment. At this time, the problem no longer is so much the identifi cation of contaminants and their sources. Rather, we are now faced with solving questions on the fates and effects of such compounds. This includes the search for mechanisms to deal effectively with the large number of chemicals already found in water, air and biota. One of such time and cost saving scientific avenues is the field of quantitative structure-activity correlations for the prediction of the environmental behavior and effects of compounds.
Download or read book QSAR in environmental toxicology written by and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in Environmental Toxicology II written by K.L. Kaiser and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few years, research in the field of quantitative structure-activity relationships (QSAR) in chemistry, biology, pharmacology, toxicology, and environmental sciences has seen strong growth. New journals and books have appeared in each of these fields, however, the combination of QSAR and environmental sciences is still in its infancy. After the success of the Workshop on Quantitative Structure-Activity Relationships (QSAR) in Environmental Toxicology, held at McMaster University, Aug ust 16-18, 1983, with the proceedings publ ished in 1984 [QSA R in Environmental Toxicology, Kaiser, K. L. E. (Ed. ), D. Reidel Pub!. Co. , Dordrecht, 406 p. , ISBN 90-277 -1776-1], it was time to hold another workshop in 1986. Indeed, the response by the scientific community was excellent with over 50 participants from Canada, Germany, Great Britain, Hungary, India, Japan, The Netherlands, United States, and Yugoslavia. Moreover, both breadth and depth of papers given were significantly improved and the workshop discussions were intense and frank. Regrettably, the number of participants, number of papers given and submitted for these proceedings made it impossible to include the workshop discussions of these papers. However, several manuscripts were revised on the basis of these discussions and, therefore, do reflect this very interactive workshop. This volume presents the majority of papers given at the 2nd International Workshop on QSAR in Environmental Toxicology, held at McMaster University, June 9-13, 1986. Many of these papers contain primary, new scientific data, equations and results which will not appear elsewhere.
Download or read book Practical Applications of Quantitative Structure Activity Relationships QSAR in Environmental Chemistry and Toxicology written by W. Karcher and published by Springer Science & Business Media. This book was released on 1990-05-31 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the Lectures given during the Eurocourse on `Practical Applications of Quantitative Structure-Activity (QSAR) in Environmental Chemistry and Toxicology' held at the Joint Research Centre Ispra, Italy, June 11--15, 1990
Download or read book QSAR EIGHTY EIGHT written by and published by . This book was released on 1988 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in environmental toxicology 3 written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in environmental toxicology 4 written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in environmental toxicology 1 written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Workshop on QSAR in Environmental Toxicology written by and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in environmental toxicology 2 written by and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR 88 written by International Workshop on QSAR in Environmental Toxicology and published by . This book was released on 1988* with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book QSAR in Environmental Toxicology IV written by Joop L. M. Hermens and published by Elsevier Publishing Company. This book was released on 1991-01-01 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the different aspects and fields of application of QSAR, such as: # Statistical techniques and estimation of physico-chemical properties # Environmental fate processes # Toxicokinetic behaviour # Environmental toxicity and mechanism of action # Application of QSAR in practice Moreover, presentations are included which deal with the mechanistic aspects of environmental fate and toxicity. Experts from these different fields ensure the exchange of information which will stimulate the development of QSAR. Another objective is to bring together the expertise of people working in the fields of drug design and the environmental sciences, since the underlying processes that lead to the beneficial effects of drugs are the same as those that cause the adverse effects of environmental pollutants. This excellent volume reflects developments at the cutting edge of a rapidly developing field.
Download or read book Chemometrics and Cheminformatics in Aquatic Toxicology written by Kunal Roy and published by John Wiley & Sons. This book was released on 2021-12-01 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das Buch Chemometrics and Cheminformatics in Aquatic Toxicology befasst sich mit den bestehenden und neu auftretenden Problemen der Verschmutzung der aquatischen Umwelt durch verschiedene metallische und organische Schadstoffe, insbesondere Industriechemikalien, Pharmazeutika, Kosmetika, Biozide, Nanomaterialien, Pestizide, Tenside, Farbstoffe und viele weitere. Es werden verschiedene chemometrische und cheminformatische Instrumente für Laien beschrieben mitsamt ihrer Anwendung auf die Analyse und Modellierung der Toxizitätsdaten von Chemikalien in Bezug auf unterschiedliche aquatische Organismen. Eine Reihe von Datenbanken zur aquatischen Toxizität sowie chemometrische Softwaretools und Webserver werden vorgestellt und praktische Beispiele für die Modellentwicklung gegeben, einschließlich der entsprechenden Abbildungen. Darüber hinaus enthält das Werk Fallstudien und Literaturberichte, um das Verständnis des Themas abzurunden. Außerdem lernen die Leserinnen und Leser Werkzeuge und Protokolle wie maschinelles Lernen, Data Mining sowie Methoden des QSAR-basierten und ligandenbasierten chemischen Designs kennen. Darüber hinaus bietet das Werk: * Eine umfassende Einführung in chemometrische und cheminformatische Instrumente und Techniken, insbesondere maschinelles Lernen und Data Mining * Eine Darstellung von Datenbanken zur aquatischen Toxizität, chemometrischen Softwaretools und Webservern * Praktische Beispiele und Fallstudien zur Verdeutlichung und Veranschaulichung der im Buch enthaltenen Konzepte * Eine kompakte Erläuterung der chemometrischen und cheminformatischen Instrumente sowie ihrer Anwendung auf die Analyse und Modellierung von Toxizitätsdaten Chemometrics and Cheminformatics in Aquatic Toxicology ist ideal für Forschende und Studierende der Chemie sowie der Umwelt- und Pharmawissenschaften und sollte auch in den Bibliotheken von Fachleuten in der chemischen Industrie sowie Aufsichtsbehörden, die sich mit Chemometrie beschäftigen, einen Platz finden.
Download or read book QSAR in Environmental Toxicology Volume 1 Proceedings of the Workshop on Quantitative Structure Activity Relationships QSAR in Environmental Toxicology Hamilton Ontario Canada August 16 18 1983 written by Kaiser KLE Ed and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Three Dimensional QSAR written by Jean Pierre Doucet and published by CRC Press. This book was released on 2010-12-17 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a result of new statistical and mathematical approaches, improved visualization tools, and recognition by international regulatory groups, quantitative structure-activity relationships (QSARs) now play important roles in pharmacology for the design of new drugs as well as in toxicology and ecotoxicology for hazard identification and risk assessm
Download or read book QSAR and SPECTRAL SAR in Computational Ecotoxicology written by Mihai V. Putz and published by CRC Press. This book was released on 2012-07-19 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: QSAR and SPECTRAL-SAR in Computational Ecotoxicology presents a collection of studies based on the epistemological bulk data-information-knowledge of the chemicals used in green chemistry. It assesses a specific model of pattern characterization of concerned active substances at the bio-, eco-, and pharmacologic levels through unitary formulation of the effector-receptor binding degree potential, including the logistic type by employing a computational algebraic quantitative structure-activity relationship (QSAR) model called SPECTRAL-SAR. It aims to minimize the residual recorded activities in the experiments that study the enzymic, ionic liquid, antagonists, and allosteric inhibition interactions. The book covers: The classic QSAR approach The new SPECTRAL-SAR approach How to draw SPECTRAL-SAR maps for predicting ecotoxicological mechanisms for a given series of toxicants and single or multi-species in an open system Biological activity as related to chemical reactivity through associate descriptors This book will be very useful in advanced courses on computational ecotoxicology, drug design and interaction, methods in quantum and computational chemistry, chemical molding, chemical bonding, and others.
Download or read book Ecotoxicological QSARs written by Kunal Roy and published by Humana. This book was released on 2021-01-31 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on computational modeling of the ecotoxicity of chemicals and presents applications of quantitative structure–activity relationship models (QSARs) in the predictive toxicology field in a regulatory context. The extensive book covers a variety of protocols for descriptor computation, data curation, feature selection, learning algorithms, validation of models, applicability domain assessment, confidence estimation for predictions, and much more, as well as case studies and literature reviews on a number of hot topics. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of practical advice that is essential for researchers everywhere. Authoritative and comprehensive, Ecotoxicological QSARs is an ideal source to update readers in the field with current practices and introduce to them new developments and should therefore be very useful for researchers in academia, industries, and regulatory bodies.
