Download or read book Handbook of Focal Therapy for Prostate and Renal Cancer written by Damian Greene and published by JP Medical Ltd. This book was released on 2016-09-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is the commonest cancer in men. Current treatments include surgery to remove the whole prostate or radiotherapy of the whole prostate. These radical treatments can treat the cancer effectively but often cause unwanted side effects. Meanwhile widespread screening with prostate-specific antigen has led to an increased diagnosis of localised prostate cancer; at the same time, widespread use of abdominal imaging has led to increased detection of renal masses. In response to demand for improved outcomes with reduced side effects, focal therapy has emerged as an important procedure in managing both prostate and renal cancers. It targets individual areas of cancer, reducing unwanted side effects and the amount of damage to collateral tissue. This new method of treatment has major advantages: it involves less radiation, the removal of less tissue and less time spent in hospital. Handbook of Focal Therapy for Prostate and Renal Cancer provides a comprehensive, timely review of targeted ablation methods to treat prostate and renal cancers. It describes the most effective techniques in current practice, with discussion of the selection criteria, ablation technologies and their limitations, and advice on the management of common side effects. The book opens with a summary of the principles of prostate and renal cancer treatment and the mechanisms of focal therapy. Separate sections on prostate and kidney follow, covering the role of focal therapy, side effects and their treatment and follow-up after targeted ablation. Written in a practical, clinically-oriented style, Handbook of Focal Therapy for Prostate and Renal Cancer is the ideal reference for urologists, radiologists and radiation oncologists wishing to employ the latest focal therapy techniques in the care of their patients.

Download or read book Hormone Therapy and Castration Resistance of Prostate Cancer written by Yoichi Arai and published by Springer. This book was released on 2018-05-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged. During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnic variation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspectives on hormone therapy for PCa. This work benefits not only Asian urologists but also their Western counterparts and all physicians and medical personnel who are involved in the treatment of PCa.

Download or read book Urologic Surgical Pathology E Book written by Liang Cheng and published by Elsevier Health Sciences. This book was released on 2014-01-24 with total page 1306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With sweeping revisions throughout, the new edition of Urologic Surgical Pathology equips you to accurately diagnose specimens of the entire urinary tract and male reproductive system plus the adrenal glands. Comprehensive in scope, this title begins with a look at normal anatomy and histology for each organ system...followed by discussions of the pathology of congenital anomalies, inflammations, non-neoplastic diseases and neoplasia. Practical guidance in daily urological pathology sign-out and the latest recommended diagnostic approaches — with an emphasis on clinicopathologic and radiographic-pathologic correlations — makes this a true diagnostic decision-making medical reference. A consistent format enables you to locate critical information quickly, and more than 1600 high-quality illustrations — most in full color — make diagnosis even easier. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Rely on the practice-proven experience of today’s authorities to identify and diagnose with confidence. Confirm your diagnostic suspicions by comparing your findings to more than 1600 color images and color graphics. Quickly locate the specific information you need through an abundance of tables, diagrams and flowcharts; boxed lists of types and causes of diseases; differential diagnosis; characteristic features of diseases; complications; classifications; and staging. Stay current with the latest information on: differential diagnosis for all tumor types encountered in urological surgical pathology practice; urologic tumor specimen handling and reporting guidelines; new entities and updated classification schemes; and newer immunohistochemical and genetic diagnostic methods. Develop targeted therapy specific to a particular patient’s problem based on key molecular aspects of disease, especially in relevance to targeted therapy/personalized medicine. Provide the clinician with the most accurate diagnostic and prognostic indicators, by incorporating the latest classification and staging systems in your reports. Deepen your understanding of new diagnostic biomarkers and their utility in differential diagnosis.

Download or read book Cancer Stem Cells written by Vinagolu K. Rajasekhar and published by John Wiley & Sons. This book was released on 2014-01-27 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.

Download or read book The Prostate Monologues written by Jack McCallum and published by Rodale. This book was released on 2013-08-20 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently diagnosed with prostate cancer and approaching surgery, Jack McCallum wanted to tackle the confusion, misconceptions, and conflicting medical advice that so many men struggle with when thinking about the disease. So he got to work writing The Prostate Monologues. Through the lens of his own experience, McCallum attacks the nitty-gritty questions about prostate cancer that men think about (but may be too bashful to ask their doctors) with honesty and humor. For example, “When is it safe to attempt intercourse, or at least, self-inflicted orgasm?” Or, if you have surgery, “What’s it like the first time you shop for adult diapers?” With wry humor, McCallum decodes the sometimes-confusing jargon of medical professionals so that it is understandable and relatable to “regular” men. Prostate cancer is the second most common cancer among men and the second most fatal. Worse than the obvious commonality and mortality of the disease, though, is the fact that prostate cancer can rob a man of his manhood. Accordingly, McCallum handles the subject not only with care and knowledge, but also with good cheer. Through the honest telling of his own story, and drawing on the latest research, McCallum shares insight into what’s worked for him—and what’s proven to work—in surviving cancer with your sense of humor intact.

Download or read book Therapeutic Ultrasound written by Jean-Michel Escoffre and published by Springer. This book was released on 2015-10-20 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.

Download or read book Prostate Cancer Imaging written by Ayman El-Baz and published by CRC Press. This book was released on 2018-10-31 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers novel strategies and state of the art approaches for automated non-invasive systems for early prostate cancer diagnosis. Prostate cancer is the most frequently diagnosed malignancy after skin cancer and the second leading cause of cancer related male deaths in the USA after lung cancer. However, early detection of prostate cancer increases chances of patients’ survival. Generally, The CAD systems analyze the prostate images in three steps: (i) prostate segmentation; (ii) Prostate description or feature extraction; and (iii) classification of the prostate status. Explores all of the latest research and developments in state-of-the art imaging of the prostate from world class experts. Contains a comprehensive overview of 2D/3D Shape Modeling for MRI data. Presents a detailed examination of automated segmentation of the prostate in 3D imaging. Examines Computer-Aided-Diagnosis through automated techniques. There will be extensive references at the end of each chapter to enhance further study.

Download or read book A Cultural Biography of the Prostate written by Ericka Johnson and published by MIT Press. This book was released on 2021-09-07 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: What contemporary prostate angst tells us about how we understand masculinity, aging, and sexuality. We are all suffering an acute case of prostate angst. Men worry about their own prostates and those of others close to them; women worry about the prostates of the men they love. The prostate--a gland located directly under the bladder--lurks on the periphery of many men's health issues, but as an object of anxiety it goes beyond the medical, affecting how we understand masculinity, aging, and sexuality. In A Cultural Biography of the Prostate, Ericka Johnson investigates what we think the prostate is and what we use the prostate to think about, examining it in historical, cultural, social, and medical contexts. Johnson shows that our ways of talking about, writing about, imagining, and imaging the prostate are a mess of entangled relationships. She describes current biomedical approaches, reports on the "discovery" of the prostate in the sixteenth century and its later appearance as both medical object and discursive trope, and explores present-day diagnostic practices for benign prostate hyperplasia--which transform a process (urination) into a thing (the prostate). Turning to the most anxiety-provoking prostate worry, prostate cancer, Johnson discusses PSA screening and the vulnerabilities it awakens (or sometimes silences) and then considers the presence of the absent prostate--how the prostate continues to affect lives after it has been removed in the name of health.

Download or read book Liquid Biopsy A Tool for Better Understanding of the Metastatic Process Ecosystem written by Elisabetta Rossi and published by Frontiers Media SA. This book was released on 2022-09-21 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Prostate Cancer written by Adam P. Dicker and published by Demos Medical Publishing. This book was released on 2014-12-17 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book admirably covers prostate cancer. It is written in an easily digestible manner for non-experts and emphasizes the importance of a team approach to treatment of patients with this disease."--Doody's Reviews With an emphasis on multidisciplinary collaboration and decision-making, this practical resource reflects the extraordinary advances in the treatment of prostate cancer during the past five years. Approximately thirty international, leading-edge investigators describe the most current evidence-based approaches to prostate cancer treatment. The book provides a comprehensive view of the entire spectrum of prostate cancer management from initial screening through novel and experimental treatments that have the potential for a major impact on practice. The book first reviews fundamental issues including epidemiology, screening, risk reduction, diagnosis and pathologic characterization, staging, and imaging. This includes strategies for improving the accuracy of PSA screening and an update on controversies surrounding the ISUP Modified Gleason Score. The book covers novel molecular and genotype profiling in prostate cancer, including morphometric and systems pathology. Detailed information is provided on radiographic imaging for diagnosis and staging. The treatment sections of the book correspond to the staging of disease. The treatment of localized disease addresses the range of multidisciplinary management options including a discussion of prostate cancer's impact on the quality of life. A detailed review of multimodal therapies (medical, surgical, and radiologic) addresses the treatment of localized advanced disease, and coverage of advanced metastatic prostate cancer reviews current management options including a range of promising novel and experimental agents. The book also discusses counseling the high-risk patient. Several chapters incorporate models of care delivery, patient navigation for multidisciplinary care, genomic and risk assessment, and comparative effects of research in treatment decision-making. The book is designed as a management text for all health care professionals who provide care for prostate cancer patients as well as patients, families, and advocates. Extensive references offer opportunities for additional study. Key Features: Delineates a practical, concise approach to multidisciplinary management of prostate cancer Provides a wide range of perspectives and expertise Written and edited by an international, multidisciplinary team of prostate cancer specialists Focuses on such key issues as special populations, screening controversies, patient counseling, and quality of life Includes discussion of important emerging topics such as gene profiling and targeted therapies and comparative effectiveness data "

Download or read book Oxford Textbook of Urological Surgery written by Freddie C. Hamdy and published by Oxford University Press. This book was released on 2017 with total page 1201 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook mapped to the curriculum for urological training as approved by the General Medical Council. This core text will be essential reading for both the trainee and specialist in urology in the UK and abroad.--[Ed.].

Download or read book Invasion of the Prostate Snatchers Revised and Updated Edition written by Mark Scholz and published by Other Press, LLC. This book was released on 2021-08-24 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable map through the medical minefield of prostate cancer, revised and updated with the latest developments in treatment options. Every year almost a quarter of a million confused and frightened American men are tossed into a prostate cancer cauldron stirred by salespeople representing a multibillion-dollar industry. Patients are too often rushed into a radical prostatectomy, a major operation that rarely prolongs life and more than half the time leaves them impotent. Invasion of the Prostate Snatchers argues that close monitoring—active surveillance rather than surgery or radiation—should be the initial treatment approach for many men at the low- and intermediate-risk stages. In a unique collaboration, doctor and patient provide a wholly new perspective on managing this disease. Ralph Blum’s account of his personal struggle, together with Dr. Mark Scholz’s presentation of new scientific advances, offers convincing evidence that this noninvasive approach can be crucial in preventing tens of thousands of men from being overtreated each year. This revised and updated second edition: -Highlights the latest prostate cancer treatment options that preserve erectile and urinary function while prolonging lifespan -Establishes updated protocol for how to accurately interpret high prostate-specific antigen (PSA) while avoiding the invasive, dangerous random biopsy -Recounts true patient stories that accurately represent the hurdles today’s patients face while navigating a prostate cancer diagnosis -Introduces the latest evidence in the radiation vs. radical prostatectomy debate -Presents the latest thinking on diet and exercise for men with prostate cancer

Download or read book Genomic Biomarkers for Pharmaceutical Development written by Elizabeth Mambo and published by Elsevier Inc. Chapters. This book was released on 2013-07-16 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this chapter is on the development of miRNA diagnostics and the process for miRNA biomarker development. We discuss pancreatic cancer as a model for the application of miRNA-based tests in different clinical biopsy specimen types. Asuragen’s miRInform® Pancreas test illustrates the development of a laboratory developed test (LDT) that was validated in compliance with Clinical Laboratory Improvement Amendments (CLIA) and College of American Pathologists (CAP) regulations. We provide an overview of work on miRNA-based signatures which is focused on resolving clinical dilemmas in solid and cystic pancreatic lesions. We also review some of the promising miRNA candidates identified in biofluids from other cancer types. These studies highlight the emergence of miRNA-based diagnostic tools which have the potential to impact the clinical management of cancer by guiding early diagnosis, aiding in the assessment of patients’ prognosis, and enabling the identification of novel, more effective therapeutic targets.

Download or read book Active Surveillance for Localized Prostate Cancer written by Laurence Klotz and published by Humana Press. This book was released on 2017-09-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

Download or read book Disease Prevention written by John Frank and published by Oxford University Press. This book was released on 2016-07-28 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preventive medical interventions and non-medicalised public health programmes that promise health benefits in the future, from actions taken now, carry a strong ethical requirement of 'first, do no harm' or primum non nocere. New preventive advice and interventions are being promoted on a daily basis, Disease Prevention: A Critical Toolkit provides a set of appraisal tools to guide those considering a preventive action to make sure that it is effective (does more good than harm), efficient (is a competitive use of scarce resources), and equitable in its impact across society. Case studies and worked examples illustrate the risks and benefits of specific preventive interventions. Divided into 10 chapters this practical and concise book focuses on multiple aspects of prevention including the hierarchy of preventive options; the assessment of causation; finding and appraising scientific evidence; prevention directed at entire populations (as opposed to individuals); measuring chronic disease risk factors and medically managing them: statin treatment of high cholesterol; PSA screening for prostate cancer; genetic screening for future disease risk; and assessing the health equity implications of prevention. Aimed at front-line public health and primary care professionals, Disease Prevention: A Critical Toolkit will equip them with the up-to-date skills necessary to help them better inform and serve their patients and communities.

Download or read book 50 Studies Every Doctor Should Know written by Michael E. Hochman and published by Oxford University Press. This book was released on 2013-10-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: 50 Studies Every Doctor Should Know presents key studies that have shaped the practice of medicine. Selected using a rigorous methodology, the studies cover topics ranging from dieting to cardiovascular disease, insomnia to obstetrics. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case concludes each review. A section of review questions and answers is included at the back of the book to ensure that readers take away the key messages from each study. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

Download or read book CURRENT Practice Guidelines in Primary Care 2013 written by Joseph S. Esherick and published by McGraw Hill Professional. This book was released on 2013-02-22 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: SUMMARIES OF THE PRACTICE GUIDELINES MOST RELEVANT TO DAILY CLINICAL PRACTICE--AT YOUR FINGERTIPS AND READY TO IMPLEMENT Spans all areas of general outpatient medicine Drawn from the most reliable sources: government agencies, medical and scientific organizations, and expert panels Easy-to-follow guideline-based algorithms speed clinical decision making Convenient, carry-anywhere size puts today's best practices in your pocket Website addresses for U.S. government agencies and professional organizations Updated immunization schedules for all age groups New evidence and references Contains 33 new chapters Includes updates to many other primary care topics Perfect for residents, family physicians, internists, and all other clinicians who care for patients