Download or read book Magnetic Resonance Spectroscopy in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

Download or read book Magnetic Resonance Spectroscopy written by Charlotte Stagg and published by Academic Press. This book was released on 2013-11-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. - Chapters written by world-leading experts in the field - Fully illustrated - Covers both proton and non-proton MRS - Includes the background to novel MRS imaging approaches

Download or read book MR Spectroscopy of Pediatric Brain Disorders written by Stefan Blüml and published by Springer Science & Business Media. This book was released on 2012-12-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Download or read book MRI from Picture to Proton written by Donald W. McRobbie and published by Cambridge University Press. This book was released on 2017-04-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Download or read book Foundations of Sport Related Brain Injuries written by Semyon M. Slobounov and published by Springer Science & Business Media. This book was released on 2006-08-25 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: In summarizing current insights and controversies over concussions in athletics, this book makes the vital point that symptom resolution does not necessarily mean injury resolution. Research shows that dysfunctional pathways continue for extended periods even after a minor concussion. Until the consequences of short-term perturbations and long-term residual brain dysfunctions are better understood, concussions must be treated with respect and given a higher priority for continued research activity.

Download or read book In Vivo NMR Spectroscopy written by Robin A. de Graaf and published by John Wiley & Sons. This book was released on 2019-03-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

Download or read book MR Spectroscopy of the Brain written by Lara Alexandre Brandão and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a practical guide to the technique and most frequent clinical applications of magnetic resonance spectroscopy (MRS) of the brain. Using more than 500 images, the authors present the fundamentals of MRS in a straightforward fashion and show radiologists and neurologists how to recognize normal and disease processes on scans. The book presents the spectra of the most common neurological disease entities, along with the conventional images and perfusion and diffusion where appropriate. The authors thoroughly describe the pathology and key MRS features of each disease process. Each chapter ends with a quick-reference summary of the main findings.

Download or read book Clinical MR Neuroimaging written by Jonathan H. Gillard and published by Cambridge University Press. This book was released on 2010 with total page 917 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers each physiological MR methodology and their applications to all major neurological diseases.

Download or read book Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases written by Else Rubaek Danielsen and published by CRC Press. This book was released on 1999-02-16 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

Download or read book Clinical MR Spectroscopy written by Peter B. Barker and published by Cambridge University Press. This book was released on 2010 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Download or read book Pediatric Neuroradiology written by Paolo Tortori-Donati and published by Springer Science & Business Media. This book was released on 2010-02-25 with total page 1785 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exhaustive text covers all aspects of diagnosis and endovascular treatment of neurological and neurosurgical diseases of the pediatric central nervous system starting from their in utero expression. It also includes the vascular malformations of each district and their endovascular treatment. Besides the "normal" imaging techniques the advanced techniques (spectroscopy, diffusion, perfusion, and functional imaging) are covered in detail. Several topics that are often only superficially dealt with in other books are herewith covered in outstanding detail. The volume is richly illustrated with high-quality neuroradiological images, with pathological correlation where applicable. The rich analytic index makes it an easily usable tool in the everyday clinical practice. The book serves both as a reference for specialists (neuroradiologists, radiologists, neurosurgeons, neurologists, pediatricians) and as a teaching text for residents and fellows-in-training.

Download or read book Magnetic Resonance of Myelin Myelination and Myelin Disorders written by Jacob Valk and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.

Download or read book Magnetic Resonance Imaging and Spectroscopy written by Fred A. Mettler and published by . This book was released on 1986 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Applications of Magnetic Resonance Spectroscopy written by Suresh K. Mukherji and published by Wiley-Liss. This book was released on 1998-04-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Applications of MR Spectroscopy Edited by Suresh K. Mukherji, M.D. Magnetic resonance spectroscopy (MRS) is a powerful diagnostic tool for a variety of brain disorders—from epilepsy and tumors to age-related degeneration and strokes. Unlike magnetic resonance imaging (MRI), which gives us a picture of anatomical and physiological conditions, MRS generates a frequency domain spectrum that provides information about biochemical and metabolic processes occurring within tissues. Clinical Applications of MR Spectroscopy presents a short, practical treatment of MRS today. Comprising contributions by leading authorities in the field, the book discusses MRS techniques used for diagnostic purposes and research, terminologies and examples drawn from clinical experience, and ways to correlate MRS results with other modalities to enhance our understanding of disease processes and the outcomes of particular treatments. Topics include: Basic principles of clinical proton magnetic resonance spectroscopy MRS in the evaluation of epilepsy Proton MRS of brain tumors Proton MRS in selected childhood disorders MRS and spectroscopic imaging for cerebrovascular disease MRS of degenerative brain disease in the elderly MRS of the head and neck Potential clinical applications of new techniques in MRS Correlation of functional brain imaging with MRS Clinical Applications of MR Spectroscopy provides 150 photographs and figures to illustrate the interpretation of MRS signals, as well as fully referenced chapters for those wishing to expand their knowledge of the underlying science. It is an essential guide to the state of the art for radiologists and neurologists using this technology to improve patient care.

Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Download or read book Handbook of Magnetic Resonance Spectroscopy In Vivo written by Paul A. Bottomley and published by John Wiley & Sons. This book was released on 2016-10-19 with total page 1231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

Download or read book Quantitative MRI of the Brain written by Paul Tofts and published by John Wiley & Sons. This book was released on 2005-08-19 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)