Download or read book Exosomes written by Lawrence R. Edelstein and published by Academic Press. This book was released on 2019-10-16 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. - Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. - Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts - Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Download or read book Current Topics in Complement written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2007-01-26 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Aegean Conferences Workshop on Complement-Associated Diseases, Animal Models, and Therapeutics convened to discuss progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of research and new experimental approaches allow an integrated view of the in vivo biology of the complement system. This book collects writings on the functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed at the conference.

Download or read book Extracellular Vesicles written by and published by BoD – Books on Demand. This book was released on 2022-07-20 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.

Download or read book Advances in Clinical Chemistry written by and published by Elsevier. This book was released on 2020-02-27 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.

Download or read book The Male Role in Pregnancy Loss and Embryo Implantation Failure written by Richard Bronson and published by Springer. This book was released on 2015-07-15 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.

Download or read book New Frontiers Extracellular Vesicles written by Suresh Mathivanan and published by Springer Nature. This book was released on 2021-03-29 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs. The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implications of EVs in intercellular communication and the significance of biologically active cargo carried within these EVs are further examined. Moreover, the numerous applications of EVs in diagnostics and treatment of diseases are reviewed in detail, particularly their potential as biomarkers and drug delivery vehicles. Taken together, this book is a compilation of the key implications of EVs that are secreted by virtually all cell types. Readers will gain a perspective into the biology, functions and applications of EVs and their constantly evolving knowledge base.

Download or read book Role of Exosomes in Biological Communication Systems written by Faisal A. Alzahrani and published by Springer Nature. This book was released on 2020-11-20 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.

Download or read book The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species Industry and Case Reports written by David Martín Hidalgo and published by MDPI. This book was released on 2021-08-16 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, assisted reproductive technologies (ARTs) have a pivotal role not only in achieving fertilization in subfertile animals, but they are also involved in the management of the herd, decreasing disease spread and even allowing offspring sex selection. Nonetheless, there are differences between species or even within species that have led researchers worldwide to focus on those differences in order to bypass these specific difficulties. This Special Issue, titled “The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports” and published in Animals, is composed of 12 original manuscripts and three reviews that offer an overview of current and future ARTs used to improve reproductive outcomes, mainly focused on farm animals, such as horse, pig, bovine, rabbit and ovine species. Thus, the Special Issue covers information from the classical point of view, including comparative studies of different semen extenders, to the most advanced technologies of sperm selection by thermotaxis or chemoattractants, as well as the improvement of sperm features by red light irradiation. The female and embryo contributions to ART outcomes are also covered, for instance, with a study that improves our knowledge by the metabolomic description of follicular fluid composition or the description of better culture conditions of oocytes. In brief, this Special Issue provides a balanced overview of emerging techniques and technologies used to preserve, improve, rescue or even create fertility for domestic farm animals with high economic impact.

Download or read book Prostate written by and published by PediaPress. This book was released on with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Prostate Cancer written by Jon Schiller and published by CreateSpace. This book was released on 2010-07-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your author decided to write this book about Prostate Cancer when one of his best friends suffered from this disease. He took extensive chemotherapy which extended his life, but made living difficult. His body was saying make me live longer, but his mind was saying I should die, living is too painful to continue. His mind finally won-out and he died. This book used Internet to learn about the symptoms of Prostate Cancer and the latest therapies used to extend the life span of people suffering from this cancer. One promising technology is the use of Nanocells which are injected in the patient's blood stream. These nanocells seek out the cancer cells and destroy them, thus curing the patient. I learned studying Nanotechnology research for another book that people investigating the applications of Nanocells had injected such synthesized cells into mice and the cells had sought out the cancer cells and destroyed them, thus curing the mice. If Bioscience researchers can do the same thing for humans, then there is hope for eradicating Prostate Cancer.

Download or read book Lycopene written by V R Preedy and published by CRC Press. This book was released on 2019-09-10 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tomatoes have become a dietary staple for humans in many parts of the world. The characteristic deep red color of the ripe tomato fruit and related products is mainly due to lycopene. Lycopene is the predominant carotenoid in tomatoes, followed by a-carotene, b-carotene, g-carotene, and phytoene, as well as by several other minor carotenoids. Tomat

Download or read book Issues in Immunology Research 2012 Edition written by and published by ScholarlyEditions. This book was released on 2013-01-10 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Immunology Research / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunogenetics. The editors have built Issues in Immunology Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunogenetics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1990-06-20 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology

Download or read book Complement Regulatory Proteins written by B. Paul Morgan and published by Academic Press. This book was released on 1999-02-18 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. - Complement regulators--structure, functional roles and mode of action - Comprehensive reviews of each of the individual regulators - Roles of Complement regulators in vivo,in health and disease: - Consequences of deficiency - Roles in the reproductive system - Interactions with pathogens - Exploitation for therapy - Complement regulators in other species

Download or read book Anticancer Research written by and published by . This book was released on 2005 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proteomics of Human Body Fluids written by Visith Thongboonkerd and published by Springer Science & Business Media. This book was released on 2008-01-23 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts. The first provides basic principles and strategies for proteomic analysis of human body fluids. The second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.

Download or read book Proteins Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 3385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Proteins. The editors have built Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.