Download or read book Handbook of Pharmaceutical Manufacturing Formulations written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2016-04-19 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth volume in the series covers the techniques and technologies involved in the preparation of semisolid products such as ointments, creams, gels, suppositories, and special topical dosage forms. Drug manufacturers need a thorough understanding of the specific requirements that regulatory agencies impose on the formulation and efficacy deter
Download or read book Handbook of Pharmaceutical Manufacturing Formulations Third Edition written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2019-12-05 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Three, Liquid Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this third volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features: Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines
Download or read book Public Health Consequences of E Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Download or read book Integrated Pharmaceutics written by Antoine Al-Achi and published by John Wiley & Sons. This book was released on 2022-09-07 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is an examination of all aspects of the science in developing effective dosage form for drug delivery Pharmaceutics refers to the subfield of pharmaceutical sciences that develops drug delivery products or devices to optimize the drug's performance once administered. This multidisciplinary field draws on physical chemistry, organic chemistry, and biophysics to generate and refine these crucial elements of medical care. Moreover, incorporating such disparate dimensions of drug product design as material properties and legal regulation bridges the gap between effective chemicals and viable medical treatments. Integrated Pharmaceutics provides a comprehensive introduction to the creation and manufacture of effective dosage forms for drug delivery. It presents its subject following the principles of physical pharmacy, product design, and drug regulations. This tripartite structure allows readers to move from theory to practice, beginning from a firm foundation of physical pharmacy principles, including drug solubility and stability estimation, rheology, and interfacial properties. From there, it proceeds to discussions of drug product design and of harmonizing pharmaceutical design with the regulatory regimens and technological standards of the United States, European Union, and Japan. Readers of the second edition of Integrated Pharmaceutics will also find: A glossary defining key terms, extensive informative appendices, and a list of references leading to the primary literature in the field for each chapter Earlier chapters are expanded, with additional new chapters including one entitled “Biotechnology Products” Supplementary instructor guide with questions and solutions available online for registered professors Updated regulatory guidelines including quality by design, design space analysis, process analytical technology, polymorphism characterization, blend sample uniformity, and stability protocols Integrated Pharmaceutics is a useful textbook for graduate students in pharmaceutical sciences, drug formulation and design, and biomedical engineering. In addition, professionals in the pharmaceutical industry, including regulatory bodies, will find it a helpful reference guide.
Download or read book Klamath National Forest N F written by and published by . This book was released on 1998 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Safety Evaluation written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2023-01-12 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Safety Evluation Comprehensive and practical guide presenting a roadmap for safety assessment as an integral part of the development of drugs and therapeutics This fourth edition of Drug Safety Evaluation maintains the central objective of presenting an all-inclusive practical guide for those who are responsible for ensuring the safety of drugs and biologics to patients, healthcare providers, those involved in the manufacture of medicinal products, and all those who need to understand how the safety of these products is evaluated and shepherding valuable candidates to market. Individual chapters address specific approaches to evaluation hazards, including problems that are encountered and their solutions. Also covered are the scientific and philosophical bases for evaluation of specific concerns (e.g., carcinogenicity, development toxicity, etc.) to provide both understanding and guidance for approaching the new problems that have come to face both our society and the new challenges they brought. The many changes in regulatory requirements, pharmaceutical development, technology, and the effects of Covid on our society and science have required both extensive revision to every chapter and the addition of four new chapters. Specific sample topics covered in Drug Safety Evaluation include: The drug development process and the global pharmaceutical marketplace and regulation of human pharmaceutical safety Sources of information for consideration in study and program design and in safety evaluation Electronic records, reporting and submission, screens in safety and hazard assessment, and formulations, routes, and dosage regimens Mechanisms and endpoints of drug toxicity, pilot toxicity testing in drug safety evaluation, and repeat dose toxicity Genotoxicity, QSAR tools for drug safety, toxicogenomics, nonrodent animal studies, and developmental and reproductive toxicity testing An appendix which provides an up to date guide to CROs for conducting studies Drug Safety Evaluation was written specifically for the pharmaceutical and biotechnology industries, including scientists, consultants, and academics, to show a utilitarian yet scientifically valid path to the everyday challenges of safety evaluation and the problem solving that is required in drug discovery and development.
Download or read book Gardner s Commercially Important Chemicals written by G. W. A. Milne and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 1205 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exhaustive resource for the industrial chemical community Through eleven editions, Gardner's Chemical Synonyms and Trade Names has become the best-known and most widely used source of information on chemicals in commerce. This companion book reflects the continuing research underlying Gardner's and presents a major expansion of the information provided for individual chemical compounds. Gardner's Commercially Important Chemicals: Synonyms, Trade Names, and Properties: * Contains 4,174 chemical entries and information such as structure, molecular formula, and chemical name * Includes synonyms for each chemical, including other identifiers, chemical names, trade names, and trivial names, in English and other languages * Provides chemical properties of the compounds, information concerning known uses of the chemical and biological data-in particular, acute toxicity in various species, where available * Lists the companies that manufacture or supply the listed chemicals * Describes bulk inorganic chemicals, major pesticides (herbicides, insecticides, antifungal agents, etc.), and many dyestuffs, surfactants, and metals, along with the most commonly used drugs * Contains indexes by chemical name and synonym, Chemical Abstracts Service (CAS) Registry Numbers, and EINECS (European Inventory of Existing Commercial Substances) numbers One useful feature of this database is the inclusion of physical properties and use data for pure chemicals. Properties that have been provided, when available, include: the melting point, boiling point, density or specific gravity, optical rotation, ultraviolet absorption, solubility, and acute toxicity. The major uses of most of the chemicals are indicated and, where appropriate, regulatory information is also provided.
Download or read book Compounded Topical Pain Creams written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain is both a symptom and a disease. It manifests in multiple forms and its treatment is complex. Physical, social, economic, and emotional consequences of pain can impair an individual's overall health, well-being, productivity, and relationships in myriad ways. The impact of pain at a population level is vast and, while estimates differ, the Centers for Disease Control and Prevention reported that 50 million U.S. adults are living in pain. In terms of pain's global impact, estimates suggest the problem affects approximately 1 in 5 adults across the world, with nearly 1 in 10 adults newly diagnosed with chronic pain each year. In recent years, the issues surrounding the complexity of pain management have contributed to increased demand for alternative strategies for treating pain. One such strategy is to expand use of topical pain medicationsâ€"medications applied to intact skin. This nonoral route of administration for pain medication has the potential benefit, in theory, of local activity and fewer systemic side effects. Compounding is an age-old pharmaceutical practice of combining, mixing, or adjusting ingredients to create a tailored medication to meet the needs of a patient. The aim of compounding, historically, has been to provide patients with access to therapeutic alternatives that are safe and effective, especially for people with clinical needs that cannot otherwise be met by commercially available FDA-approved drugs. Compounded Topical Pain Creams explores issues regarding the safety and effectiveness of the ingredients in these pain creams. This report analyzes the available scientific data relating to the ingredients used in compounded topical pain creams and offers recommendations regarding the treatment of patients.
Download or read book Approved Drug Products and Legal Requirements written by Thomson Micromedex and published by PDR Network. This book was released on 2007 with total page 1948 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book USP DI written by and published by . This book was released on 1997 with total page 1536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vol. 1 of each ed. contains drug information for the health care professional. Vol. 2 includes advice for the patient in lay language and vol. 3. covers approved drug products and legal requirements.
Download or read book Food Hydrocolloids written by Martin Glucksman and published by Taylor & Francis. This book was released on 2022-07-30 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1982, this three-volume set explores the value of hydrocolloids in food. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for dieticians and other practitioners in their respective fields.
Download or read book Core Concepts in the Disorders of Fluid Electrolytes and Acid Base Balance written by David Mount and published by Springer Science & Business Media. This book was released on 2012-08-04 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluid, electrolyte, and acid-base disorders are central to the day-to-day practice of almost all areas of patient-centered medicine – both medical and surgical. Virtually every aspect of these disorders has experienced major developments in recent years. Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance encompasses these new findings in comprehensive reviews of both pathophysiology and clinical management. In addition, this volume offers clinical examples providing step-by-step analysis of the pathophysiology, differential diagnosis, and management of selected clinical problems. Written by leading experts in fluid, electrolyte, and acid-base disorders, this reference is an invaluable resource for both the nephrologist and the non-specialist physician, or medical trainee.
Download or read book Regulation of Food Additives and Medicated Animal Feeds written by United States. Congress. House. Committee on Government Operations. Intergovernmental Relations Subcommittee and published by . This book was released on 1971 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Legislative History of the Federal Food Drug and Cosmetic Act and Its Amendments written by United States and published by . This book was released on 1979 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Legislative History of the Federal Food Drug and Cosmetic Act and Its Amendments written by and published by . This book was released on 1979 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Food Additives and Medicated Animal Feeds written by United States. Congress. House. Government Operations and published by . This book was released on 1971 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
