Download or read book Cardiovascular Calcification written by Michael Henein and published by Springer. This book was released on 2022-09-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book systematically describes the clinical and scientific aspects of cardiovascular calcification. Chapters detail the mechanisms associated with arterial and valve calcification, relevant risk factors, pathophysiology and the latest therapeutic techniques. Recent diagnostic technological developments including how computed tomography (CT) scanning can be utilized along with Agatston score to quantify coronary arterial calcification when investigating whether a patient for sub-clinical atherosclerosis are covered. The correlation with the presence of arterial calcification and extent of coronary stenosis is also explored. Cardiovasular Calcification details relevant aspects of the basic science and reviews the latest pathological and therapeutic techniques used in treating patients with cardiovascular calcification. It is therefore an essential resource for practicing cardiologists, cardiac surgeons, vascular specialists and radiologists.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Pathophysiology of Cardiovascular Disease written by Naranjan S. Dhalla and published by Springer. This book was released on 2012-10-31 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.
Download or read book Stroke Genetics written by Hugh S. Markus and published by . This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. An increasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke. Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemic stroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence is reviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing a practical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Download or read book Evolution of Cardio Metabolic Risk from Birth to Middle Age written by Gerald S. Berenson and published by Springer Science & Business Media. This book was released on 2011-07-09 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: That precursors of adult coronary artery disease, hypertension, and type II diabetes begin in childhood have been clearly established by the Bogalusa Heart Study. This unique research program has been able to follow a biracial (black/white) population over 35 years from childhood through mid-adulthood to provide perspectives on the natural history of adult heart diseases. Not only do these observations describe trajectories of cardio-metabolic risk variables leading to these diseases but provide a rationale for the need to begin prevention beginning in childhood. The trajectories of the burden of cardio-metabolic risk variables in the context of their fetal origin and chromosome telomere dynamics provide some insight into the metabolic imprinting in utero and aging process. The observed racial contrasts on cardio-metabolic risk variables implicate various biologic pathways interacting with environment contributing to the high morbidity and mortality from related diseases in our population. To address the seriousness of the onset of cardiovascular disease in youth, approaches to primordial prevention are described focussing on childhood health education as an important aspect of Preventive Cardiology.
Download or read book Early Vascular Aging EVA written by Pedro Guimarães Cunha and published by Elsevier. This book was released on 2024-02-29 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. - Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) - Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities - Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations
Download or read book Epicardial Adipose Tissue written by Gianluca Iacobellis and published by Springer Nature. This book was released on 2020-03-25 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease. It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease. Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.
Download or read book The Asia Pacific Perspective written by Asia-Pacific Steering Committee and published by . This book was released on 2000 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Life Course Approach to Healthy Ageing written by Diana Kuh and published by Oxford University Press, USA. This book was released on 2014 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title investigates the lifetime determinants of healthy ageing and their implications for policy and practice, bringing together authorities in ageing research and knowledge transfer from across the world.
Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Coronary Microvascular Dysfunction written by Filippo Crea and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
Download or read book Hypertension in Children and Adolescents written by Empar Lurbe and published by Springer. This book was released on 2019-07-29 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to hypertension in children and adolescents, a clinical issue that – thanks to the strides made in several areas of pathophysiological and clinical research – has received growing interest in cardiovascular medicine over the last several years. Given the increasing prevalence of hypertension in children and adolescents, this book represents an important and useful tool to address what has become a significant public health issue. It covers a diverse range of topics, from advances in the definition of hypertension and the identification of new risk factors, to current treatment strategies. The book also presents an overview of the latest findings, including the clinical significance of isolated systolic hypertension (ISH) in youth, the importance of out-of-office and central blood pressure measurement, new methods for assessing vascular phenotypes, and clustering of CV risk factors. Gathering contributions by international experts and pursuing a practice-oriented approach, the book offers a valuable tool for cardiologists, pediatricians and nephrologists, as well as general practitioners.
Download or read book Atlas of Cardiovascular Computed Tomography written by Matthew J. Budoff and published by Springer. This book was released on 2018-05-23 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is a comprehensive visual reference for the use of cardiovascular computed tomography (CT) containing photomicrographs, anatomic illustrations, tables, and charts paired with extensive legends and explanations that are supplemented by extensive research, peer-reviewed articles, and textbooks. In addition to providing historical perspective and current direction for CT, this new edition of Atlas of Cardiovascular Computed Tomography 2e focuses on research involving coronary artery diseases and anomalies, congestive heart failure, atherosclerotic plaques and asymptomatic disease, as well as imaging techniques, including preparation, acquisition, and processing, involving the great vessels and carotids, the peripheral vasculature, and coronary and pulmonary veins. The increasing role of CT in the emergency room and in private cardiology practice is also reviewed thoroughly, making this an essential read for all involved in cardiac imaging, cardiology and emergency medicine.
Download or read book Cardiorenal Syndrome written by Adel E. Berbari and published by Springer Science & Business Media. This book was released on 2010-10-04 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease. Several pathophysiologic mechanisms have been postulated to explain the relationship between renal dysfunction and cardiovascular disease. Recent studies indicate an integrated response of the vascular smooth muscles and glomerular mesangial cells to traditional and uremia related cardiovascular risk factors. Traditional risk factors can incite renal impairment and cardiac damage. As renal function deteriorates, uremia-related risk factors play an increasing role both in reduction in glomerular filtration rate and cardiovascular damage. Several uremia related factors such as uncontrolled hypertension, disturbed glucose insulin metabolism, microalbuminuria, phosphate retention, secondary hyperparathyroidism, myocardial and vascular calcification, hypertensive-uremic cardiomyopathy, inflammation, oxidant injury, and neurohormonal dysregulation have been implicated in the pathogenesis of the cardiorenal syndrome. Recent data suggest that management of the cardiorenal syndrome requires aggressive control of traditional risk factors as well novel approaches to prevent or reverse uremia –related processes. This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology, pathophysiologic mechanisms, and therapeutic approaches.
Download or read book Prevention of Myocardial Infarction written by JoAnn E. Manson and published by Oxford University Press, USA. This book was released on 1996 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease remains the leading cause of death in both men and women in most industrialized countries. Yet it is largely preventable, and health care providers can acquire the skills to help their patients reduce their risks substantially. Traditional risk factors such as cigarette smoking, hypercholesterolimia, hypertension, sedentary lifestyle, obesity and glucose intolerance explain a major proportion of coronary events. Recent evidence also suggests important adjunctive roles for hormone replacement therapy in postmenopausal women, and aspirin prophlaxis in individuals at high risk of a first myocardial infarction. Emerging evidence indicates an important role for diet in the prevention of heart disease. Although the importance of lifestyle and behavioral modifications may well be known among physicians and other health-care providers, the implementation of this knowledge has been limited. One reason is that the information supporting the value, feasibility and cost-effectiveness of risk-reduction strategies has not been previously synthesized and made widely available to health-care providers in office and community settings. Prevention of Myocardial Infarction fills these critical gaps by providing a state-of-the-art compendium of the scientific evidence on the efficacy of coronary disease prevention, while focusing on helping clinicians develop intervention skills to utilize available knowledge. Chapters by leading authorities in cardiovascular epidemiology, clinical cardiology, cost-effectiveness analysis, and public health translate the theory of preventive cardiology into feasible implementation. The counseling and other intervention strategies described in this textbook have documented clinical efficacy and cost-effectiveness, and they require little time to learn or implement. The book is written mainly for primary care providers, including general internists and family physicians, but will also be of interest to medical subspecialties such as cardiologists and endocrinologists, as well as medical students, dietitians, psychologists, epidemiologists, and students, practitioners, and researchers in public health.
Download or read book Comprehensive Cardiovascular Medicine in the Primary Care Setting written by Peter P. Toth and published by Springer Science & Business Media. This book was released on 2010-07-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Cardiovascular Medicine in the Primary Care Setting provides an authoritative, detailed discussion of cardiovascular disease balanced with practical utility. Disease states are explained with emphasis on risk factors, risk estimation, and established cardiac disease. The book also delves into the co-morbid conditions which surround cardiovascular disease, including peripheral vascular disease, chronic kidney disease, depression, and erectile dysfunction, with the goal of improving quality of life for affected individuals. An abundance of algorithms, case studies, and recommendations on evidence-based best practices facilitate rapid learning. A key resource for the busy practitioner, this book is designed to give the reader the skills to confidently perform assessments, initiate and maintain efficacious therapy, and know when a referral to a cardiologist is advisable.
Download or read book Secondhand Smoke Exposure and Cardiovascular Effects written by Institute of Medicine and published by National Academies Press. This book was released on 2010-02-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data suggest that exposure to secondhand smoke can result in heart disease in nonsmoking adults. Recently, progress has been made in reducing involuntary exposure to secondhand smoke through legislation banning smoking in workplaces, restaurants, and other public places. The effect of legislation to ban smoking and its effects on the cardiovascular health of nonsmoking adults, however, remains a question. Secondhand Smoke Exposure and Cardiovascular Effects reviews available scientific literature to assess the relationship between secondhand smoke exposure and acute coronary events. The authors, experts in secondhand smoke exposure and toxicology, clinical cardiology, epidemiology, and statistics, find that there is about a 25 to 30 percent increase in the risk of coronary heart disease from exposure to secondhand smoke. Their findings agree with the 2006 Surgeon General's Report conclusion that there are increased risks of coronary heart disease morbidity and mortality among men and women exposed to secondhand smoke. However, the authors note that the evidence for determining the magnitude of the relationship between chronic secondhand smoke exposure and coronary heart disease is not very strong. Public health professionals will rely upon Secondhand Smoke Exposure and Cardiovascular Effects for its survey of critical epidemiological studies on the effects of smoking bans and evidence of links between secondhand smoke exposure and cardiovascular events, as well as its findings and recommendations.
