Download or read book Progress in Monogenic Hair Disorders written by Eli Sprecher and published by Nova Publishers. This book was released on 2005 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present monograph, leading figures in the field of genetic hair research summarise major recent advances. View as a whole, these reviews of each of the major areas of hair genodermatology not only illustrate the importance of recent findings to our understanding of skin biology and the management of hair disorders, but also underscore the relevance of hair genetic research to non-cutaneous pathologies. The wealth of recent discoveries combined with the application of emergent technologies to the study of hair biology and diseases have placed this discipline at the forefront of biological research, generating unprecedented challenges for investigative dermatology that are transpiring throughout this new and pioneering book.

Download or read book Ichthyoses written by and published by Karger Medical and Scientific Publishers. This book was released on 2010-01-01 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors' overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a 'best attempt' by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment. The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features. This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading.

Download or read book Alopecias Practical Evaluation and Management written by D. Ioannides and published by Karger Medical and Scientific Publishers. This book was released on 2015-02-26 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hair is subject to either intrinsic (i.e. physiological) aging or extrinsic (i.e. premature) aging that can be attributed to external factors. The intrinsic factors can be associated with genetic mechanisms and are subject to individual variations, whereas external factors include ultraviolet radiation, air pollution, smoking, and possibly nutrition. Leading experts have contributed to this book which offers a practical approach to the evaluation and management of various forms of alopecia, including their pathogenesis, the diagnostic procedures involved, medical treatments, and nutritional issues. A completely new surgical technique for hair transplantation that leaves behind sufficient follicle unit tissue to regenerate hairs is also described. Being comprehensive and easy-to-read, this book should be very useful for dermatologists who wish to diagnose and treat their patients with hair problems more effectively.

Download or read book Risk Factors for Cerebrovascular Disease and Stroke written by Sudha Seshadri and published by Oxford University Press. This book was released on 2016-03-07 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases. An international group of professionals the forefront of research and education, provide their expertise about environmental and genetic determinants for cerebrovascular disease and stroke. The authors aim to provide information on developments of genetic, environmental and lifestyle-related risk factors of various subtypes of stroke, and MRI-markers of cerebrovascular disease. One in two men, and one in three women after the age of 40, will develop a stroke in their lifetime. The burden of cerebrovascular disease extends far beyond that of acute clinical events such as stroke, with "covert" vascular injury on brain MRI being highly prevalent in older community-dwelling persons. Therefore, improving our understanding of the risk factors for stroke and cerebrovascular disease is of paramount importance for improving prevention strategies. Secular trends in stroke epidemiology, risk factors, and intermediate markers (including carotid ultrasound, brain MRI and circulating biomarkers) are presented. Cutting edge information on genetic, environmental and lifestyle-related risk factors of various subtypes of stroke and MRI-markers of cerebrovascular diseases are displayed. This important book is an essential reference to physicians interested in more effective primary prevention of stroke.

Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Download or read book Biotechnological Advances for Microbiology Molecular Biology and Nanotechnology written by Jyoti Ranjan Rout and published by CRC Press. This book was released on 2022-04-27 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology: An Interdisciplinary Approach to the Life Sciences presents cutting-edge research associated with the beneficial implications of biotechnology on human welfare. The volume mainly focuses on the highly demanding thrust areas of biotechnology that are microbiology, molecular biology, and nanotechnology. The book provides a detailed overview of the beneficial roles of microbes and nanotechnology-based engineered particles in biological developments. Also, it highlights the role of epigenetic machinery and redox modulators during the development of diseases. In addition, it provides research on nanotechnology-based applications in tissue engineering, stem cell, and regenerative medicines. Overall, the book provides an extended platform for acquiring the methodological knowledge needed for today’s biotechnological applications, such as DNA methylation, redox homeostasis, CRISPR, nano-based drug delivery systems, proteomics, genomics, metagenomics, bioluminescence, bioreactors, bioremediation, biosensors, etc. Divided into three sections, the book first highlights some recent trends in applied microbiology used in different areas, such as crop improvement, wastewater treatment, drug delivery, healthcare management, and more. The volume goes on to cover some advances in cellular and molecular mechanisms, such as CRISPR technology in biological systems, induced stem cells in disease prevention, integrated omics technology, and others. The volume also explores the indispensable role of nanotechnology in the precisely modulating intricate functioning of an organism in diagnostic and therapy along its application in tissue engineering and regenerative medicine and in food science as well as its role in ecological sustainability. This multidisciplinary volume will be highly valuable for the researchers, scientists, biologists, and faculty and students striving to expand their horizon of knowledge in their respective fields.

Download or read book IADVL Textbook of Trichology written by BS Chandrashekar and published by JP Medical Ltd. This book was released on 2018-06-30 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trichology is the science of the structure, function and diseases of the human hair. This book is a comprehensive guide to the diagnosis and treatment of diseases and disorders of the hair and scalp. Divided into six sections, the text begins with an overview of hair and the normal scalp, factors controlling hair growth and changes that occur during the aging process. The next section discusses diagnostic trichology methods including microscopy and trichoscopy. The following chapters detail the diagnosis and treatment of numerous hair disorders covering both clinical and surgical procedures, for common and more complex conditions. A chapter on recent advances in surgical management is included. The final section discusses interdisciplinary issues in the management of hair disorders such as paediatric, psychiatric, gynaecologic and endocrinologic liaison therapy. Each chapter begins with a ‘key messages’ box and concludes with a summary of the topic. The book is highly illustrated with clinical photographs, diagrams and tables. Key points Comprehensive guide to the diagnosis and management of diseases and disorders of the hair and scalp Covers both clinical and surgical treatment methods Features discussion on liaison therapy between different medical disciplines Highly illustrated with clinical photographs, diagrams, tables and boxes

Download or read book Male Alopecia written by Ralph M. Trüeb and published by Springer Science & Business Media. This book was released on 2014-02-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides specialists and primary care physicians who are interested in hair with the practical know-how needed to achieve successful management of male alopecia. Guidance is first provided on the examination of hair loss in men, covering such aspects as clinical examination, the role of trichoscopy and the trichogram, laboratory work-up and scalp biopsy. Diagnosis and treatment are then described in depth for a diverse range of conditions involving alopecia. Expert opinion is combined with the results of evidence-based medicine to provide the best current advice, highlighting the synergistic action of combination regimens and adjuvant treatments and explaining the concept of multitargeted treatment. All aspects of follow-up are covered, including compliance issues and expectation management. The role of hair care and cosmetics is also considered, with identification of potential adverse effects as well as benefits.

Download or read book Surface Antigens Advances in Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Antigens: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Surface Antigens in a concise format. The editors have built Surface Antigens: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Surface Antigens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Surface Antigens: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Female Alopecia written by Ralph M. Trüeb and published by Springer Science & Business Media. This book was released on 2013-02-26 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few dermatologic problems carry as many emotional overtones as hair loss in women, which is by far the most common hair problem encountered in daily clinical practice. Fortunately, a specific diagnosis can usually be established through the application of appropriate examinations and tests, and treatment suited to the diagnosis is likely to control the problem. This comprehensively illustrated monograph provides both specialists and primary care physicians with the practical know-how required for successful management of hair loss in female patients of all ages. The book opens by critically examining various myths about hair loss. The different examination techniques are then described, and the various forms of hair loss and their treatment are discussed in detail. Approaches to follow-up are outlined, and the management of patient expectations is carefully considered. The potential role of hair care and cosmetics is also explored in some depth.

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Download or read book Idiopathic Pulmonary Fibrosis written by Ulrich Costabel and published by European Respiratory Society. This book was released on 2016-03-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.

Download or read book The Difficult Hair Loss Patient written by Ralph M. Trüeb and published by Springer. This book was released on 2015-09-02 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: You could read every textbook available on hair growth and disorders, and still not be able to treat hair loss effectively. In every art, there are many techniques, but few principles. The only way to achieve success is to have a firm foundation of principles to build upon, and the right attitude about how to achieve your goals. This book offers a detailed guide that goes beyond the technical aspects of trichology and evidence based medicine, providing specialists and primary care physicians experienced in the basic management of hair loss with the additional know-how they need to master the ultimate challenge of difficult hair loss patients. First, the prerequisites for successful management of hair loss are reviewed – basically, making a diagnosis and understanding the patient and his or her problem. Then, guidelines on the management of difficult dermatologic conditions and of psychopathological disorders associated with hair loss are provided. Lastly, important aspects of follow-up are covered–specifically the problems of adverse effects, patient non-compliance, and their management–before concluding with exemplary case studies of successful treatment of alopecia and related conditions.

Download or read book Genetics of Endocrine Diseases and Syndromes written by Peter Igaz and published by Springer Nature. This book was released on 2019-10-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of genetic counseling. Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases. In recent years, there have been major developments in our understanding of the genetic basis of endocrine diseases. Several novel genes and mutations predisposing individuals to monogenic endocrine diseases have been discovered, and with the advent of next generation sequencing, a huge amount of new data has become available. Further, novel molecular mechanisms, such as genomic imprinting, have been implicated in the pathogenesis of endocrine diseases. A better understanding of the genetic background of these diseases is relevant not only from the research perspective, but also in terms of clinical care. As such, this book is an essential read for both researchers and clinicians working in the field.

Download or read book Atlas of Genodermatoses written by Ruggero Caputo and published by CRC Press. This book was released on 2005-12-12 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: A lavishly illustrated guide to almost 200 inherited diseases of the skin, hair, and nails. Each entry includes synonyms, age of onset, clinical findings, complications, course, laboratory findings, diagnosis, therapy, and key references, adding up to far more than just a collection of photographs. In addition to being a clinical primer, this is also a work of scientific research and contains the first printed description of two new syndromes. The fast-moving world of genetic research means that the latest genetic correlations, included here, render previous texts out of date. All specialists in Dermatology and Pediatrics should find this an invaluable front-line resource in the clinic.

Download or read book American Book Publishing Record written by and published by . This book was released on 2003 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Autism Spectrum Disorders written by Andreas M. Grabrucker and published by . This book was released on 2021 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.