Download or read book Antifungal Drug Discovery New Theories and New Therapies written by Chaminda Jayampath Seneviratne and published by Frontiers Media SA. This book was released on 2016-09-13 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.

Download or read book What We Didn t Expect written by Melody Schreiber and published by Melville House. This book was released on 2020-11-10 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year, 400,000 families in the United States welcome premature babies ... Ten percent of babies born in the U.S. are preemies. But that one word, "preemie," encompasses a range of medical and cultural experiences. There are textbooks, medical-ish guidebooks, and the occasional memoir to turn to ... but no book that collects personal experiences from the many people who have parented, cared for, or been preemies themselves. Until now. In What We Didn't Expect, journalist Melody Schreiber brings together a chorus of acclaimed writers and thinkers to share their diverse stories of having or being premature babies. The stories here cover everything from life-changing tests of faith to navigating the red tape of healthcare bureuacracy; from overcoming unimaginable grief to surviving and thriving against all odds. The result is a moving, heartfelt book, and a crucial and informative resource for anyone who has, or is about to have, the experience of dealing with a premature birth.

Download or read book The Handbook of Journal Publishing written by Sally Morris and published by Cambridge University Press. This book was released on 2013-02-21 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date and comprehensive handbook written by experienced professionals, covering all aspects of journal publishing, both online and in print.

Download or read book Scholarship in the Digital Age written by Christine L. Borgman and published by MIT Press. This book was released on 2010-08-13 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of the technical, social, legal, and economic aspects of the scholarly infrastructure needed to support research activities in all fields in the twenty-first century. Scholars in all fields now have access to an unprecedented wealth of online information, tools, and services. The Internet lies at the core of an information infrastructure for distributed, data-intensive, and collaborative research. Although much attention has been paid to the new technologies making this possible, from digitized books to sensor networks, it is the underlying social and policy changes that will have the most lasting effect on the scholarly enterprise. In Scholarship in the Digital Age, Christine Borgman explores the technical, social, legal, and economic aspects of the kind of infrastructure that we should be building for scholarly research in the twenty-first century. Borgman describes the roles that information technology plays at every stage in the life cycle of a research project and contrasts these new capabilities with the relatively stable system of scholarly communication, which remains based on publishing in journals, books, and conference proceedings. No framework for the impending “data deluge” exists comparable to that for publishing. Analyzing scholarly practices in the sciences, social sciences, and humanities, Borgman compares each discipline's approach to infrastructure issues. In the process, she challenges the many stakeholders in the scholarly infrastructure—scholars, publishers, libraries, funding agencies, and others—to look beyond their own domains to address the interaction of technical, legal, economic, social, political, and disciplinary concerns. Scholarship in the Digital Age will provoke a stimulating conversation among all who depend on a rich and robust scholarly environment.

Download or read book Handbook of Quantitative Science and Technology Research written by Henk F. Moed and published by Springer Science & Business Media. This book was released on 2004-09-10 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook offers a state-of-the-art overview of quantitative science and technology research. It focuses on the development and application of indicators derived from data on scientific or scholarly publications and patents. It comprises 34 chapters written by leading specialists in the various sub-domains. These chapters deal with theoretical and methodological issues, illustrate applications, and highlight their policy context and relevance. Authors present a survey of the research topics they address, and show their most recent achievements. The 34 chapters are arranged into 5 parts: Disciplinary Approaches; General Methodology; The Science System; The Technology System; and The Science–Technology Interface. The Editor’s Introduction provides a further specification of the handbook’s scope and of the main topics addressed in its chapters. This handbook aims at four distinct groups of readers: – practitioners in the field of science and technology studies; – research students in this field; – scientists, scholars and technicians who are interested in a systematic, thorough analysis of their activities; – policy makers and administrators who wish to be informed about the potentialities and limitations of the various approaches and about their results.

Download or read book Reproducibility and Replicability in Science written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Download or read book Opening Science written by Sönke Bartling and published by Springer. This book was released on 2013-12-16 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern information and communication technologies, together with a cultural upheaval within the research community, have profoundly changed research in nearly every aspect. Ranging from sharing and discussing ideas in social networks for scientists to new collaborative environments and novel publication formats, knowledge creation and dissemination as we know it is experiencing a vigorous shift towards increased transparency, collaboration and accessibility. Many assume that research workflows will change more in the next 20 years than they have in the last 200. This book provides researchers, decision makers, and other scientific stakeholders with a snapshot of the basics, the tools, and the underlying visions that drive the current scientific (r)evolution, often called ‘Open Science.’

Download or read book The Science of Science written by Dashun Wang and published by Cambridge University Press. This book was released on 2021-03-25 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive overview of the exciting field of the 'science of science'. With anecdotes and detailed, easy-to-follow explanations of the research, this book is accessible to all scientists, policy makers, and administrators with an interest in the wider scientific enterprise.

Download or read book Fraud in the Lab written by Nicolas Chevassus-au-Louis and published by Harvard University Press. This book was released on 2019-08-13 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a journalist and former lab researcher, a penetrating investigation of the explosion in cases of scientific fraud and the factors behind it. In the 1970s, a scientific scandal about painted mice hit the headlines. A cancer researcher was found to have deliberately falsified his experiments by coloring transplanted mouse skin with ink. This widely publicized case of scientific misconduct marked the beginning of an epidemic of fraud that plagues the scientific community today. From manipulated results and made-up data to retouched illustrations and plagiarism, cases of scientific fraud have skyrocketed in the past two decades, especially in the biomedical sciences. Fraud in the Lab examines cases of scientific misconduct around the world and asks why this behavior is so pervasive. Nicolas Chevassus-au-Louis points to large-scale trends that have led to an environment of heightened competition, extreme self-interest, and emphasis on short-term payoffs. Because of the move toward highly specialized research, fewer experts are qualified to verify experimental findings. And the pace of journal publishing has exacerbated the scientific rewards system—publish or perish holds sway more than ever. Even when instances of misconduct are discovered, researchers often face few consequences, and falsified data may continue to circulate after an article has been retracted. Sharp and damning, this exposé details the circumstances that have allowed scientific standards to decline. Fraud in the Lab reveals the intense social pressures that lead to fraud, documents the lasting impact it has had on the scientific community, and highlights recent initiatives and proposals to reduce the extent of misconduct in the future.

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book Index of NLM Serial Titles written by National Library of Medicine (U.S.) and published by . This book was released on 1984 with total page 1584 pages. Available in PDF, EPUB and Kindle. Book excerpt: A keyword listing of serial titles currently received by the National Library of Medicine.

Download or read book Open Access and the Public Domain in Digital Data and Information for Science written by National Research Council and published by National Academies Press. This book was released on 2004-06-14 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This symposium, which was held on March 10-11, 2003, at UNESCO headquarters in Paris, brought together policy experts and managers from the government and academic sectors in both developed and developing countries to (1) describe the role, value, and limits that the public domain and open access to digital data and information have in the context of international research; (2) identify and analyze the various legal, economic, and technological pressures on the public domain in digital data and information, and their potential effects on international research; and (3) review the existing and proposed approaches for preserving and promoting the public domain and open access to scientific and technical data and information on a global basis, with particular attention to the needs of developing countries.

Download or read book Mining Scientific Papers NLP enhanced Bibliometrics written by Iana Atanassova and published by Frontiers Media SA. This book was released on 2019-10-09 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Scientist s Guide to Writing written by Stephen B. Heard and published by Princeton University Press. This book was released on 2016-04-12 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and accessible primer on the scientific writer's craft The ability to write clearly is critical to any scientific career. The Scientist's Guide to Writing provides practical advice to help scientists become more effective writers so that their ideas have the greatest possible impact. Drawing on his own experience as a scientist, graduate adviser, and editor, Stephen Heard emphasizes that the goal of all scientific writing should be absolute clarity; that good writing takes deliberate practice; and that what many scientists need are not long lists of prescriptive rules but rather direct engagement with their behaviors and attitudes when they write. He combines advice on such topics as how to generate and maintain writing momentum with practical tips on structuring a scientific paper, revising a first draft, handling citations, responding to peer reviews, managing coauthorships, and more. In an accessible, informal tone, The Scientist's Guide to Writing explains essential techniques that students, postdoctoral researchers, and early-career scientists need to write more clearly, efficiently, and easily. Emphasizes writing as a process, not just a product Encourages habits that improve motivation and productivity Explains the structure of the scientific paper and the function of each part Provides detailed guidance on submission, review, revision, and publication Addresses issues related to coauthorship, English as a second language, and more

Download or read book How to Write and Publish a Scientific Paper written by Robert A. Day and published by Cambridge University Press. This book was released on 1989-03-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Elements of Style written by William Strunk Jr. and published by Arcturus Publishing. This book was released on 2023-10-01 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1918, William Strunk Jr.'s The Elements of Style is a guide to writing in American English. The boolk outlines eight "elementary rules of usage", ten "elementary principles of composition", "a few matters of form", a list of 49 "words and expressions commonly misused", and a list of 57 "words often misspelled". A later edition, enhanced by E B White, was named by Time magazine in 2011 as one of the 100 best and most influential books written in English since 1923.

Download or read book Research Abstracts of the Scientific Program written by Getty Conservation Institute. Scientific Program and published by Getty Publications. This book was released on 1994 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents current research being conducted under the auspices of the Getty Conservation Institute.An overview of research from 1984 to 1994, including environmental controls in museums, the use of protective materials and analyses in the conservation of cultural objects and archaeological sites, and the use of new technologies for monitoring, documentation, and analysis.