Download or read book Prediction of Protein Adsorption on Engineered Surfaces for Biomedical and Industrial Applications written by Maria Eugenia Arias Montecillo and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This thesis describes the advancement of the Bio-molecular Adsorption Database (BAD) to more accurately predict protein adsorption. To advance the model of the BAD, data was first: collected from published literature in the last ten years, processed to be added to BAD, and used in calculations to advance the BAD ability to accurately predict protein adsorption.Protein adsorption at solid-liquid interfaces is crucial in many biomedical and industrial applications. These applications include biomaterials, protein microarrays, lab-on-a-chip devices and bioreactors. (Vasina et al., 2009)In the biomaterial area, the first response after contact of an implant material with a biological fluid, is the adsorption of proteins on to the surface. The adsorbed protein layer plays a role in the regulation of the biological response to the material and therefore bio-compatibility. It is from the adsorbed protein layer that the cells in the system obtain information about the foreign surface determining the cell behaviour. This cell behaviour can range from: adhesion establishment and proliferation of cells in the proximity to the material or the rejection and inflammation at the interface due to over layering and denaturation. (Wilson, Clegg, Leavesley, & Pearcy, 2005)In the protein microarrays and micro/nano- devices area, protein adsorption is of interest because of the need finding an optimum balance to maximized sensitivity and/or activity for analytical functions. This is done by preserving the proteins native characteristics and minimizing protein denaturation. (Vasina et al., 2009)In the bioreactors area, protein adsorption plays a role in membrane fouling, leading to increased pressures of operation and frequent biofouling clear out. As such, it is important to choose materials and conditions to minimize protein adsorption and biofouling in bioreactors. (Ognier, Wisniewski, & Grasmick, Influence of macromolecule adsorption during filtration of a membrane bioreactor mixed liquor suspension, 2002)Regardless of the considerable attention and research in the last 50 years, protein adsorption prediction had not been attained with sufficient accuracy for engineering applications. The original work into BAD, addressed protein adsorption prediction by archiving protein adsorption data and applying statistical analysis to the data. (Vasina et al., 2009)This approach correlated accurately the input variables to protein adsorption. Examples include: protein concentration in solution, protein characteristics, fluid environment conditions and surface parameters to the output variable or protein concentration on the surface. (Vasina et al., 2009)" --

Download or read book Controlling Nonspecific Adsorption of Proteins at Bio interfaces for Biosensor and Biomedical Applications written by Harshil D. Dhruv and published by . This book was released on 2009 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Partitioning of poly(ethyleneglycol) (PEG) molecules in 2-D and 3-D systems is presented as a self-assembly approach for controlling non-specific adsorption of proteins at interfaces.

Download or read book Encyclopedia of Biomaterials and Biomedical Engineering written by Gary Wnek and published by CRC Press. This book was released on 2008-05-28 with total page 3145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by more than 400 subject experts representing diverse academic and applied domains, this multidisciplinary resource surveys the vanguard of biomaterials and biomedical engineering technologies utilizing biomaterials that lead to quality-of-life improvements. Building on traditional engineering principles, it serves to bridge advances in materials science, life sciences, nanotechnology, and cell biology to innovations in solving medical problems with applications in tissue engineering, prosthetics, drug delivery, biosensors, and medical devices. In nearly 300 entries, this four-volume Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition, covers: essential topics integral to tissue engineering research: bioreactors, scaffolding materials and fabrication, tissue mechanics, cellular interaction, and development of major tissues and organs being attempted by researchers worldwide; artificial lungs and muscles, bio-artificial livers, and corneal, dental, inner ear, and total hip implants; tissue engineering of blood vessels, heart valves, ligaments, microvascular networks, skeletal muscle, and skin; bone remodeling, bone cement, and bioabsorbable bone plates and screws; controlled drug delivery, insulin delivery, and transdermal and ocular implant-based drug delivery; endovascular stent grafts, vascular grafts, and xenografts; 3-D medical imaging, electrical impedance imaging, and intravascular ultrasound; biomedical, protein adsorption, and in vivo cardiovascular modeling; polymer foams, biofunctional and conductive polymers, and electroactive polymeric materials; blood–material interactions, the bone–implant interface, host reactions, and foreign body responses and much more.

Download or read book Protein Adsorption to Surfaces with Varying Characteristics written by Yeong-Shang Lin and published by . This book was released on 1993 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Kinetics of Protein Adsorption on Synthetic and Modified Natural Surfaces written by Gene Alan Bornzin and published by . This book was released on 1980 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biological Interactions on Materials Surfaces written by David A. Puleo and published by Springer Science & Business Media. This book was released on 2009-06-26 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.

Download or read book Polymeric Biomaterials Revised and Expanded written by Severian Dumitriu and published by CRC Press. This book was released on 2001-11-29 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering nearly 7000 references-3900 more than the first edition-Polymeric Biomaterials, Second Edition is an up-to-the-minute source for plastics and biomedical engineers, polymer scientists, biochemists, molecular biologists, macromolecular chemists, pharmacists, cardiovascular and plastic surgeons, and graduate and medical students in these disciplines. Completely revised and updated, it includes coverage of genetic engineering, synthesis of biodegradable polymers, hydrogels, and mucoadhesive polymers, as well as polymers for dermacosmetic treatments, burn and wound dressings, orthopedic surgery, artificial joints, vascular prostheses, and in blood contacting systems.

Download or read book The Engineering Index Bioengineering Abstracts written by and published by . This book was released on 1987 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials written by Munmaya Mishra and published by CRC Press. This book was released on 2017-08-16 with total page 1800 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials presents new and selected content from the 11-volume Biomedical Polymers and Polymeric Biomaterials Encyclopedia. The carefully culled content includes groundbreaking work from the earlier published work as well as exclusive online material added since its publication in print. A diverse and global team of renowned scientists provide cutting edge information concerning polymers and polymeric biomaterials. Acknowledging the evolving nature of the field, the encyclopedia also features newly added content in areas such as tissue engineering, tissue repair and reconstruction, and biomimetic materials.

Download or read book Electrochemical Sensors Biosensors and their Biomedical Applications written by Xueji Zhang and published by Academic Press. This book was released on 2011-04-28 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. - Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors - Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples - Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors

Download or read book Colloid and Interface Science in Pharmaceutical Research and Development written by Hiroyuki Ohshima and published by Elsevier. This book was released on 2014-07-23 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs. - Provides a clear description of the fundamentals of colloid and interface science relevant to drug research and development - Explains the physicochemical/colloidal basis of pharmaceutical science - Lists modern experimental characterization techniques, provides analytical equations and explanations on analyzing the experimental data - Describes the most advanced techniques, AFM (Atomic Force Microscopy), SFA (Surface Force Apparatus) in detail

Download or read book Theory of Colloid and Interfacial Electric Phenomena written by Hiroyuki Ohshima and published by Elsevier. This book was released on 2006-09-05 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory of Colloid and Interfacial Electric Phenomena is written for scientists, engineers, and graduate students who want to study the fundamentals and current developments in colloid and interfacial electric phenomena, and their relation to stability of suspensions of colloidal particles and nanoparticles in the field of nanoscience and nanotechnology. The primary purpose of this book is to help understand how the knowledge on the structure of electrical double layers, double layer interactions, and electrophoresis of charged particles will be important to understand various interfacial electric phenomena and to improves the reader's skill and save time in the study of interfacial electric phenomena. Also providing theoretical background and interpretation of electrokinetic phenomena and many approximate analytic formulas describing various colloid and interfacial electric phenomena, which will be useful and helpful to understand these phenomena analyse experimental data. Showing the fundamentals and developments in the field First book to describe electrokinetics of soft particles Providing theoretical background and interpretation of electrokinetic phenomena

Download or read book Papers Presented at the Meeting written by American Chemical Society. Division of Polymer Chemistry and published by . This book was released on 1997 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Polymers for Biomedical Applications written by Anil Mahapatro and published by American Chemical Society. This book was released on 2008-04-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.

Download or read book Advances in Elastomers II written by P. M. Visakh and published by Springer Science & Business Media. This book was released on 2013-04-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume of a two-volume work which summarizes in an edited format and in a fairly comprehensive manner many of the recent technical research accomplishments in the area of Elastomers. “Advances in Elastomers” discusses the various attempts reported on solving these problems from the point of view of the chemistry and the structure of elastomers, highlighting the drawbacks and advantages of each method. It summarize the importance of elastomers and their multiphase systems in human life and industry, and covers all the topics related to recent advances in elastomers, their blends, IPNs, composites and nanocomposites. This second volume is deals with composites and nanocomposites of elastomers.

Download or read book Bioengineering Abstracts written by and published by . This book was released on 1987 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Free Energy Calculations written by Christophe Chipot and published by Springer Science & Business Media. This book was released on 2007-01-08 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react. Examples of problems in which knowledge of the underlying free energy behaviour is required, include conformational equilibria and molecular association, partitioning between immiscible liquids, receptor-drug interaction, protein-protein and protein-DNA association, and protein stability. This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles. The book is aimed at a broad readership of graduate students and researchers having a background in chemistry, physics, engineering and physical biology.