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Book Prediction and prevention of prescription drug abuse

Download or read book Prediction and prevention of prescription drug abuse written by Julie A. Marusich and published by RTI Press. This book was released on 2013-07-22 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2011, the prevalence of prescription drug abuse exceeded that of any other illicit drug except marijuana. Consequently, efforts to curtail abuse of new medications should begin during the drug development process, where abuse liability can be identified and addressed before a candidate medication has widespread use. The first step in this process is scheduling with the Drug Enforcement Agency so that legal access is appropriately restricted, dependent upon levels of abuse risk and medical benefit. To facilitate scheduling, the Food and Drug Administration (FDA) has published guidance for industry that describes assessment of abuse liability. The purpose of this paper is to review methods that may be used to satisfy the FDA's regulatory requirements for animal behavioral and dependence pharmacology. Methods include psychomotor activity, self-administration (an animal model of the rewarding effects of a drug), drug discrimination (an animal model of the subjective effects of a drug), and evaluation of tolerance and dependence. Data from tests with known drugs of abuse illustrate typical results. While the use of preclinical data to predict abuse liability is an imperfect process, these methods have substantial predictive validity. The ultimate goal is to increase consumer safety through appropriate scheduling of new medications.

Book Prediction and Prevention of Prescription Drug Abuse

Download or read book Prediction and Prevention of Prescription Drug Abuse written by Julie A. Marusich and published by . This book was released on 2013 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Pain Management and the Opioid Epidemic

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Book Facing Addiction in America

    Book Details:
  • Author : Office of the Surgeon General
  • Publisher : Createspace Independent Publishing Platform
  • Release : 2017-08-15
  • ISBN : 9781974580620
  • Pages : 420 pages

Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.

Book Preventing  Identifying  and Treating Prescription Drug Misuse Among Active duty Service Members

Download or read book Preventing Identifying and Treating Prescription Drug Misuse Among Active duty Service Members written by Rosalie Liccardo Pacula and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Prescription drug misuse (PDM) is of critical concern for the military because of its potential impact on military readiness, the health and well-being of military personnel, and associated health care costs. The purpose of this report is to summarize insights gleaned from a series of activities that the RAND Corporation undertook for the Deputy Assistant Secretary of Defense for Readiness to address this important health and military readiness issue. The authors completed a review of U.S. Department of Defense policies and a comprehensive literature review of clinical guidelines and the empirical literature on the prevention and treatment of PDM and conducted individual face-to-face interviews with 66 health and behavioral health care providers at nine medical treatment facilities across three regions within the contiguous United States to identify best practices in the prevention, identification, and treatment of PDM and the extent to which those practices are known and followed. The report also presents the framework of an analytic tool that, once informed by data available to the military but not available to the authors, can assist the military in predicting future trends in PDM based on current demographics of active-duty service members and rates of injury and prescribing of prescription drugs. The findings from this work led the authors to formulate a set of key insights that they believe might improve the rapid identification and treatment of service members dealing with PDM, thereby improving future force readiness"--

Book Preventing Drug Use Among Children and Adolescents

Download or read book Preventing Drug Use Among Children and Adolescents written by Elizabeth B. Robertson and published by . This book was released on 2004-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the goals of the Nat. Institute on Drug Abuse is to help the public understand the causes of drug abuse and to prevent its onset. This newest edition of "Preventing Drug Use Among Children and Adolescents" includes updated principles, new questions and answers, new program information, and expanded references and resources. Chapters: Introduction; Preventive Principles; Risk Factors and Protective Factors; Planning for Drug Abuse Prevention in the Community; Applying Prevention Principles to Drug Abuse Prevention Programs; Examples of Research-Based Drug Abuse Prevention Programs; and Selected Resources and References.

Book Drugs  Brains  and Behavior

Download or read book Drugs Brains and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book TIP 35  Enhancing Motivation for Change in Substance Use Disorder Treatment  Updated 2019

Download or read book TIP 35 Enhancing Motivation for Change in Substance Use Disorder Treatment Updated 2019 written by U.S. Department of Health and Human Services and published by Lulu.com. This book was released on 2019-11-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivation is key to substance use behavior change. Counselors can support clients' movement toward positive changes in their substance use by identifying and enhancing motivation that already exists. Motivational approaches are based on the principles of person-centered counseling. Counselors' use of empathy, not authority and power, is key to enhancing clients' motivation to change. Clients are experts in their own recovery from SUDs. Counselors should engage them in collaborative partnerships. Ambivalence about change is normal. Resistance to change is an expression of ambivalence about change, not a client trait or characteristic. Confrontational approaches increase client resistance and discord in the counseling relationship. Motivational approaches explore ambivalence in a nonjudgmental and compassionate way.

Book Theories on Drug Abuse

    Book Details:
  • Author : National Institute on Drug Abuse. Division of Research
  • Publisher :
  • Release : 1980
  • ISBN :
  • Pages : 534 pages

Download or read book Theories on Drug Abuse written by National Institute on Drug Abuse. Division of Research and published by . This book was released on 1980 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book National Survey on Drug Abuse

Download or read book National Survey on Drug Abuse written by and published by . This book was released on 1983 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Bridging the Gap Between Practice and Research

Download or read book Bridging the Gap Between Practice and Research written by Institute of Medicine and published by National Academies Press. This book was released on 1998-08-11 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, most substance abuse treatment is administered by community-based organizations. If providers could readily incorporate the most recent advances in understanding the mechanisms of addiction and treatment, the treatment would be much more effective and efficient. The gap between research findings and everyday treatment practice represents an enormous missed opportunity at this exciting time in this field. Informed by real-life experiences in addiction treatment including workshops and site visits, Bridging the Gap Between Practice and Research examines why research remains remote from treatment and makes specific recommendations to community providers, federal and state agencies, and other decision-makers. The book outlines concrete strategies for building and disseminating knowledge about addiction; for linking research, policy development, and everyday treatment implementation; and for helping drug treatment consumers become more informed advocates. In candid language, the committee discusses the policy barriers and the human attitudesâ€"the stigma, suspicion, and skepticismâ€"that often hinder progress in addiction treatment. The book identifies the obstacles to effective collaboration among the research, treatment, and policy sectors; evaluates models to address these barriers; and looks in detail at the issue from the perspective of the community-based provider and the researcher.

Book Medications for Opioid Use Disorder Save Lives

Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Book Young Adults in the Workplace

Download or read book Young Adults in the Workplace written by Jeremy W. Bray and published by RTI Press. This book was released on 2011-02-28 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Substance Abuse and Mental Health Services Administration funded the multisite Young Adults in the Workplace (YIW) initiative to study the effectiveness of diverse approaches to workplace-based prevention of substance abuse. Six teams adapted evidence-based programs to target young employees and then implemented the programs in retail, restaurant, health care, construction, skilled trade, and transportation industry workplaces. This book describes the programs, the adaptation and implementation processes, and the YIW cross-site evaluation.

Book Reducing Underage Drinking

    Book Details:
  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release : 2004-03-26
  • ISBN : 0309089352
  • Pages : 761 pages

Download or read book Reducing Underage Drinking written by Institute of Medicine and published by National Academies Press. This book was released on 2004-03-26 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol use by young people is extremely dangerous - both to themselves and society at large. Underage alcohol use is associated with traffic fatalities, violence, unsafe sex, suicide, educational failure, and other problem behaviors that diminish the prospects of future success, as well as health risks â€" and the earlier teens start drinking, the greater the danger. Despite these serious concerns, the media continues to make drinking look attractive to youth, and it remains possible and even easy for teenagers to get access to alcohol. Why is this dangerous behavior so pervasive? What can be done to prevent it? What will work and who is responsible for making sure it happens? Reducing Underage Drinking addresses these questions and proposes a new way to combat underage alcohol use. It explores the ways in which may different individuals and groups contribute to the problem and how they can be enlisted to prevent it. Reducing Underage Drinking will serve as both a game plan and a call to arms for anyone with an investment in youth health and safety.

Book Brief Alcohol Screening and Intervention for College Students  BASICS

Download or read book Brief Alcohol Screening and Intervention for College Students BASICS written by Linda A. Dimeff and published by Guilford Press. This book was released on 1999-01-08 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This instructive manual presents a pragmatic and clinically proven approach to the prevention and treatment of undergraduate alcohol abuse. The BASICS model is a nonconfrontational, harm reduction approach that helps students reduce their alcohol consumption and decrease the behavioral and health risks associated with heavy drinking. Including numerous reproducible handouts and assessment forms, the book takes readers step-by-step through conducting BASICS assessment and feedback sessions. Special topics covered include the use of DSM-IV criteria to evaluate alcohol abuse, ways to counter student defensiveness about drinking, and obtaining additional treatment for students with severe alcohol dependency. Note about Photocopy Rights: The Publisher grants individual book purchasers nonassignable permission to reproduce selected figures, information sheets, and assessment instruments in this book for professional use. For details and limitations, see copyright page.

Book Treatment Improvement Protocol  TIP  63  Medications for Opioid Use Disorder

Download or read book Treatment Improvement Protocol TIP 63 Medications for Opioid Use Disorder written by Substance Abuse Mental Health Services Administration/SAMHSA (U.S.) and published by Government Printing Office. This book was released on 2018-06-05 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Treatment Improvement Protocol (TIP) reviews the use of the three Food and Drug Administration (FDA)-approved medications used to treat opioid use disorder (OUD)—methadone, naltrexone, and buprenorphine—and provides guidance for healthcare professionals and addiction treatment providers on appropriate prescribing practices for these medications and effective strategies for supporting the patients utilizing medication for the treatment of OUD. The goal of treatment for opioid addiction or OUD is remission of the disorder leading to lasting recovery. Recovery is a process of change through which individuals improve their health and wellness, live self-directed lives, and strive to reach their full potential. This TIP also educates patients, families, and the general public about how OUD medications work and the benefits they offer. Related products: Medication-Assisted Treatment of Opioid Use Disorder: Pocket Guide A Shared Burden: The Military and Civilian Consequences of Army Pain Management Since 2001 Click our Alcoholism, Smoking & Substance Abuse collection to find more resources on this topic.

Book The Validity of Self reported Drug Use

Download or read book The Validity of Self reported Drug Use written by Lana D. Harrison and published by . This book was released on 1997 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: