Download or read book Practical Toxicology written by David Woolley and published by CRC Press. This book was released on 2017-03-16 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.
Download or read book Toxicological Risk Assessment of Chemicals written by Elsa Nielsen and published by CRC Press. This book was released on 2008-02-21 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk
Download or read book Developmental and Reproductive Toxicology written by Ronald D. Hood and published by CRC Press. This book was released on 2005-08-30 with total page 1164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e
Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by John Wiley & Sons. This book was released on 2018-11-05 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author’s training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Download or read book Handbook of Forensic Toxicology for Medical Examiners written by D. K. Molina, M.D. and published by CRC Press. This book was released on 2018-10-03 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic professionals, particularly medical examiners—often working through heavy caseloads—require quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is often needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their reported non-toxic, toxic, and lethal concentrations, making it an ideal text for quick reference in the lab or autopsy room. Features of the Second Edition: Explains the principles of postmortem toxicology and the factors which must be considered Provides tables of toxicologic data for over 200 commonly encountered substances, including drugs of abuse, poisons, prescription drugs, and over-the-counter medications Includes discussion and description of the novel psychoactive drugs—including synthetic opioids, cannabinoids, stimulants and hallucinogens Supplemental appendices provide additional information regarding specimen types and selection, testing methodologies, normal laboratory values, and conversion charts The busy forensic professional needs a concise handbook that provides critical information quickly and accurately. This heavily referenced text offers an easy-to-use format allowing for rapid access for both routine daily use and preparation for courtroom testimony.
Download or read book A Guide to Practical Toxicology written by David Woolley and published by CRC Press. This book was released on 2008-09-22 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, user-friendly, and informative text surveys basic principles of toxicology. It is an invaluable guide to evaluating toxicity and related data, approaching toxicity testing and interpretation, and understanding the concepts of hazard prediction and risk assessment and management. A Guide to Practical Toxicology: examines how to evaluate various groups of chemicals—pharmaceuticals, cosmetics, and agrochemicals provides insights on toxicity determination, normality and naturality, prediction, and regulation Two all-new chapters cover: safety pharmacology evaluation of different chemical classes
Download or read book Principles and Practice of Skin Toxicology written by Robert Chilcott and published by John Wiley & Sons. This book was released on 2008-07-31 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.
Download or read book A Guide to Practical Toxicology written by David Woolley and published by CRC Press. This book was released on 2003-02-20 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology is a means to an important end: safety. The effective toxicologist begins with this in mind, and uses a clear understanding of safety as a relative concept, together with a rational view of the current safety evaluation paradigm to direct their work. Too often this approach is ignored or discouraged by traditional practice. This lucid, readable book encourages both experienced toxicologists and those in training to place toxicological investigation in such a framework. It looks at the importance of toxicological normality, reviews toxicity testing methods, and explores new and 'alternative' methods of safety evaluation. The interpretation of toxicity findings in individual studies and data packages and the prediction of human-relevant hazards are reviewed, followed by an introduction to risk and how we perceive and assess risk in the light of known hazards and the probability of their occurrence. The final stage of the toxicological process, risk assessment and management, is reviewed with particular reference to the work-place. A Guide to Practical Toxicology uses text boxes to give background information on specific subjects or to act as simple guides to toxicological method or process; this is supported by tables and case-studies intended to illustrate method, study design and interpretation. These features mean the book works at different levels, suitable for professional and student toxicologists as well as those from outside the field who require some knowledge of toxicological method and interpretation, for instance in occupational hygiene or medicine and veterinary surgery.
Download or read book Forensic Medicine and Toxicology Practical Manual 1st Edition E Book written by Shankar M Bakkannavar and published by Elsevier India. This book was released on 2017-12-30 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Practical manual is designed to address the need of the undergraduate medical students to help them to face the practical examination with ease. This prepares the students adequately in practical aspects. Salient features: Contains both practical and viva sections Practical section contains exercises as well as Objective Structured Practical Examination questions Each practical is supported by specific objectives, inference and opinions Each practical is followed by practice exercise Helps the students to learn practicals by themselves Each practical contains a video link which students can download and get a classroom experience while preparing Viva section contains most frequently asked must know and nice to know questions during practical examinations Contains both practical and viva sections Practical section contains exercises as well as Objective Structured Practical Examination questions Each practical is supported by specific objectives, inference and opinions Each practical is followed by practice exercise Helps the students to learn practicals by themselves Each practical contains a video link which students can download and get a classroom experience while preparing
Download or read book Practical Toxicology written by Rudolf Kobert and published by . This book was released on 1897 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Practical Toxicology written by Rudolf Kobert and published by . This book was released on 2019-01-03 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology
Download or read book Principles of Toxicology written by Phillip L. Williams and published by John Wiley & Sons. This book was released on 2003-10-10 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms
Download or read book Pharmaceutical Toxicology in Practice written by Alberto Lodola and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Download or read book Animal Clinical Chemistry written by G.O. Evans and published by CRC Press. This book was released on 1996-04-29 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.
Download or read book Principles of Toxicology Second Edition written by Stine Karen and published by CRC Press. This book was released on 2006-01-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:
Download or read book Practical Toxicology for Physicians and Students written by Rudolf Kobert and published by . This book was released on 1898 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
