Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Download or read book Potential Human Reproductive and Development Effects of Bisphenol A written by Michael D. Shelby and published by DIANE Publishing. This book was released on 2010-05 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Center for the Evaluation of Risks to Human Reproduction (CERHR) conducted an evaluation of the potential for Bisphenol A to cause adverse effects on reproduction and development in humans. Bisphenol A is a high production volume chemical used primarily in the production of polycarbonate plastics and epoxy resins, both of which are used in some food and drink containers. CERHR selected it for evaluation because of the: Widespread human exposure; Public concern for possible health effects from human exposures; High production volume; and Evidence of reproductive and developmental toxicity in laboratory animal studies. This monograph includes a Brief on Bisphenol A and the Expert Panel Report on Bisphenol A. Charts and tables.

Download or read book Bisphenol A written by Pinar Erkekoglu and published by BoD – Books on Demand. This book was released on 2017-06-07 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bisphenol A (BPA) is a synthetic compound for hardening and clearing polycarbonate plastics. BPA is mainly classified as an estrogen-like endocrine-disrupting chemical. In the last decade, attention has arisen in scientific communities that it is not safe to use this chemical in mainly polycarbonate plastics. Exposure to BPA starts in prenatal period, which is the critical period for its toxic effects on different organs. Throughout this book, the readers will obtain information on the effects of BPA on different systems. They will also get information on the prenatal and postnatal effects of BPA. We believe that readers will get qualified scientific knowledge and a general overview of the toxic effects of BPA exposure and its consequences from this book.

Download or read book Female Reproductive Dysfunction written by Felice Petraglia and published by Springer. This book was released on 2020-05-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading international specialists, this book provides a comprehensive, state-of-the-art overview of endocrine-based female reproductive disorders. Particularly focusing on the Hypothalamus – Pituitary – Ovary (HPO) axis as the main driver of reproduction in women, it discusses amenorrhea; chronic anovulation and polycystic ovary syndrome as the most common dysfunctions of the HPO axis; endocrine diseases as possible impacts on the HPO axis; uterine disorders related to estrogen/progesterone; and the impact of endometriosis and uterine fibroids on reproduction. It also addresses infertility and menopause as hormone-related disorders in women and endocrine changes during pregnancy and lactation, and in breast disorders. The book is intended as a major reference for endocrinologists, gynecologists, and obstetricians, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which provides access to live editions constantly updated through a dynamic peer-review publishing process.

Download or read book An Atlas of Human Blastocysts written by Lucinda L. Veeck and published by CRC Press. This book was released on 2003-03-28 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing information from the cutting edge of reproductive technology, this full-color atlas vividly illustrates the typical and atypical morphology of human blastocysts collected and cultured during the course of in vitro fertilization treatments. The narrative and the illustrations detail a variety of new reproductive technologies. All photographs are supported by detailed legends and a glossary of terms is included. This atlas is edited by two world-class embryologists both of whom work at the Center for Reproductive Medicine and Infertility at the Weill Medical College of Cornell University.

Download or read book Count Down written by Shanna H. Swan and published by Simon and Schuster. This book was released on 2022-02-08 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: An award-winning scientist, in this urgent, thought-provoking and meticulously researched book, shows how chemicals in the modern environment are changing--and endangering--human sexuality and fertility on the grandest scale.

Download or read book Advances in Mitochondrial Medicine written by Roberto Scatena and published by Springer Science & Business Media. This book was released on 2012-03-08 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.

Download or read book Environmental Health Risk written by Marcelo Larramendy and published by BoD – Books on Demand. This book was released on 2016-06-16 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, Environmental Health Risk - Hazardous Factors to Living Species, is intended to provide a set of practical discussions and relevant tools for making risky decisions that require actions to reduce environmental health risk against environmental factors that may adversely impact human health or ecological balances. We aimed to compile information from diverse sources into a single volume to give some real examples extending concepts of those hazardous factors to living species that may stimulate new research ideas and trends in the relevant fields.

Download or read book Marine Anthropogenic Litter written by Melanie Bergmann and published by Springer. This book was released on 2015-06-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.

Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2002 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Research on Environmental and Human Health Impacts of Plastic Pollution written by Khursheed Ahmad Wani and published by IGI Global, Engineering Science Reference. This book was released on 2019-06-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book examines the negative impacts of plastic and explores different biotechnological interventions to plastic pollution. It also generates an awareness of the use of plastics and its impact on the environment, human health, and other ecosystems"--

Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 426 Developmental Neurotoxicity Study written by OECD and published by OECD Publishing. This book was released on 2007-10-15 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...

Download or read book Environmental Impacts on Reproductive Health and Fertility written by Tracey J. Woodruff and published by Cambridge University Press. This book was released on 2010-01-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Download or read book Reproductive and Developmental Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2022-02-11 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Toxicology** Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Download or read book Bisphenol A and Phthalates written by Bradley C. Vaughn and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bisphenol A is a difunctional building block of several important plastics and plastic additives. Suspected of being hazardous to humans since the 1930s, concerns about the use of bisphenol A in consumer products were regularly reported in the news media in 2008 after several governments issued reports questioning its safety, causing some retailers to remove products made of it from their shelves. Additionally, phthalates, are esters of phthalic acid and are mainly used as plasticisers (substances added to plastics to increase their flexibility, transparency, durability, and longevity). They are primarily used to soften polyvinyl chloride. This book examines both bisphenol A and phthalates discussing and presenting numerous topical and related data on these compounds and their uses, health effects and environmental risks.