Download or read book Posttranslational Protein Modifications in the Reproductive System written by Peter Sutovsky and published by Springer. This book was released on 2014-07-16 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book's aim is to increase the awareness of a great variety of posttranslational modifications in the male and female reproductive system. Some of the most intriguing reproductive strategies, mechanisms, and pathways involving PTM are discussed, with an added angle of evolutionary conservation and diversity. The book also chapters on sperm-egg binding, as well as on histone modification in both the embryo and sperm. Chapters are also devoted to protein ubiquitination, the regulation of sperm function during fertilization in mammals and tubulin modifications in gametes and embryos. There are no other current books on posttranslational protein modifications as they relate to reproduction, making this contribution unique in the field. It is useful for both researchers and graduate students alike.
Download or read book New Impact on Protein Modifications in the Regulation of Reproductive System written by and published by . This book was released on 2005 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Download or read book Reproductive and Developmental Strategies written by Kazuya Kobayashi and published by Springer. This book was released on 2018-06-01 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides new insights into the universality of biological systems in animal reproduction and development by a comparative study of a variety of mechanisms in animals ranging from basal invertebrates to vertebrates, including mammals. Animals accomplish genetic diversity through meiosis and fertilization, and during embryogenesis animals must produce specialized cell types, including germ cells, in accordance with their individual body plan. This series of phenomena is essential to the continuity of life in the animal kingdom, and animals show various reproductive and developmental strategies. This volume, comprising four parts, reviews animal kingdom diversity, including reproductive strategies and germ cell differentiation mechanisms (Part 1), sex determination and differentiation (Part2), the mechanisms of fertilization (Part 3), and body axis formation (Part 4). Readers will find descriptions of the reproduction or development of 180 species, 13 phyla, 35 classes, 74 orders, 117 families, and 151 genera in this book. Of particular interest is the diversity of molecules and mechanisms used to achieve the same biological purpose in different animals. Undergraduates, graduate students, and professional scientists who want a deeper understanding of animal reproductive and developmental mechanisms will find this book to be of great value.
Download or read book Intermediate Filament Proteins written by and published by Academic Press. This book was released on 2016-01-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intermediate Filament Proteins, the latest volume in the Methods in Enzymology series covers all the intermediate filaments in vertebrates and invertebrates, providing a unique understanding of the multiple different tissue-specific intermediate filaments. This volume also covers the latest methods that are currently being used to study intermediate filament protein function and dynamics. It will be an important companion for any experimentalist interesting in studying this protein family in their cell or organism model system.
Download or read book Current Concepts in Bovine Reproduction written by A. Kumaresan and published by Springer Nature. This book was released on 2022-06-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides updated information on the current concepts in bovine reproduction. It describes the complex issues associated with fertility and infertility in bovines and suggests strategies for achieving high reproductive efficiency. It discusses topics related to the fertility trend in bovines, estrus detection, controlled breeding, postpartum uterine health, uterine infections, and its therapeutic management. The essential roles of metabolic hormones on gonadal functions and fertility are also covered. Additionally, the book presents new insights in maternal recognition of pregnancy in bovines and suggest nutritional strategies to improve reproductive efficiency. The chapters on male fertility provide current information on semen cryopreservation, sperm quality assessment and measures to improve sperm fertility. A special chapter on intricacies in buffalo semen cryopreservation and measures to improve the quality of cryopreserved sperm is also included in this book. Lastly, the book introduces the immunobiological roles of anti-microbial peptides during sperm transport in reproductive tract and epigenetic bearing on fertility. This book is an invaluable resource for veterinary scientists, students and practitioners to understand the current developments in bovine reproduction for improving reproductive efficiency.
Download or read book Quantitative Methods in Proteomics written by Katrin Marcus and published by Humana Press. This book was released on 2012-06-08 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein modifications and changes made to them, as well as the quantities of expressed proteins, can define the various functional stages of the cell. Accordingly, perturbations can lead to various diseases and disorders. As a result, it has become paramount to be able to detect and monitor post-translational modifications and to measure the abundance of proteins within the cell with extreme sensitivity. While protein identification is an almost routine requirement nowadays, reliable techniques for quantifying unmodified proteins (including those that escape detection under standard conditions, such as protein isoforms and membrane proteins) is not routine. Quantitative Methods in Proteomics gives a detailed survey of topics and methods on the principles underlying modern protein analysis, from statistical issues when planning proteomics experiments, to gel-based and mass spectrometry-based applications. The quantification of post-translational modifications is also addressed, followed by the “hot” topics of software and data analysis, as well as various overview chapters which provide a comprehensive overview of existing methods in quantitative proteomics. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Quantitative Methods in Proteomics serves as a comprehensive and competent overview of the important and still growing field of quantitative proteomics.
Download or read book Cellular Mechanics and Biophysics written by Claudia Tanja Mierke and published by Springer Nature. This book was released on 2020-10-30 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.
Download or read book Human Reproduction written by Heide Schatten and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: In vitro fertilization (IVF) and other assisted reproductive technologies (ART) have become a significant part of human reproduction, with already one in 50 children worldwide being born through ART and the demand steadily increasing. To accommodate the various kinds of infertility problems, new methods have been developed to increase IVF and ART success rates and it has also become possible to treat sperm, eggs, and embryos in culture to improve reproductive success, to increase the health state of an embryo, and to prevent disease in the developing child. Human Reproduction: Updates and New Horizons focuses on recent developments and new approaches to study egg and sperm cells and embryo development, as well as addressing the increasing demand for IVF and ART to overcome infertility problems of various kinds that are encountered by an increasing number of couples worldwide. The book includes 10 chapters written by experts in their specific fields to provide information on sperm selection techniques and their relevance to ART; In vitro maturation of human oocytes: current practices and future promises; Molecular biology of endometriosis; Novel immunological aspects for the treatment of age-induced ovarian and testicular infertility, other functional diseases, and early and advanced cancer immunotherapy; Mitochondrial manipulation for infertility treatment and disease prevention; Novel imaging techniques to assess gametes and preimplantation embryos; Clinical application of methods to select in vitro fertilized embryos; New horizons/developments in time-lapse morphokinetic analysis of mammalian embryos; The non-human primate model for early human development; Cytoskeletal functions, defects, and dysfunctions affecting human fertilization and embryo development. This book will appeal to a large interdisciplinary audience, including researchers from both the basic science and medical communities. It will be a valuable reference for IVF clinicians, patients and prospective patients who are considering ART procedures, embryologists, cell biologists and students in the field of reproduction.
Download or read book Posttranslational Modification of Proteins written by Christopher Walsh and published by Roberts and Company Publishers. This book was released on 2006 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the major classes of posttranslational modifications, Posttranslational Modification of Proteins is the first comprehensive treatment of this burgeoning area of proteome diversification.
Download or read book Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders written by Maurizio Popoli and published by Springer. This book was released on 2014-07-28 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Textbook of Clinical Embryology written by Eliezer Girsh and published by Cambridge University Press. This book was released on 2021-05-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide for trainee embryologists and medical students in the specialized techniques and technology of assisted reproduction.
Download or read book The Centrosome and its Functions and Dysfunctions written by Heide Schatten and published by Springer Nature. This book was released on 2022-12-16 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.
Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Download or read book Reactive Oxygen Species and Male Fertility written by Cristian O'Flaherty and published by MDPI. This book was released on 2020-12-02 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) are inevitable by-products of aerobic cells. A delicate balance between ROS production and antioxidant defences is essential to assure cell function. This requirement is also true for the spermatozoon, the male gamete, with the unique goal of carrying and delivering the paternal genome into the oocyte. Oxidative stress promotes damage in lipids, proteins and DNA of spermatozoa, and this oxidative damage is associated with infertility. The ROS-dependent damage could occur at different stages of the production and maturation of the sperm. On the other hand, low and controlled levels of ROS are necessary to trigger and regulate sperm function. When ejaculated, spermatozoa are incapable of fertilizing the egg. They must reside in the oviduct of the female genital tract to undergo a yet to be understood the biochemical process called capacitation. Once capacitated, the spermatozoon undergoes the exocytotic event called acrosome reaction and fertilize the oocyte. ROS regulate the different molecular mechanisms such as sperm motility, capacitation and acrosome reaction to assure fertilization. This Special Issue includes original research and reviews of literature concerning the role of reactive oxygen species in male reproduction, particularly the role of antioxidants in the regulation of male fertility as well as basic and clinical studies using antioxidant-based strategies for the treatment of male infertility.
Download or read book Advances in Post Translational Modifications of Proteins and Aging written by V. Zappia and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 56 contributions presented at the 1st International Symposium on Post-Translational Modifications of Proteins and Ageing, held on the Island of Ischia (Naples, Italy) from May 11 to 15, 1987, under the auspices of the University of Naples and the Italian Society of Biochemistry. The primary aim of this interdisciplinary meeting was to promote a productive exchange among scientists from different cultural areas, and to give them the opportunity to discuss problems of common interest approached from different scientific standpoints. Although a large number of studies has led to a definition of the chemical mechanisms and of the main enzymological aspects of the several post-translational modifications of proteins, we are still far away from a complete elucidation of the functional significance of such processes. As a matter of fact, it seems reasonable that the presently available experi mental approaches and models employed to investigate the biological roles are still inadequate. The search for suitable model systems was a matter of discussion during the meeting, and will be a major challenge in the future. The most frequently employed approaches to this problem thus far have been in vitro, but several proteins reported to be excellent in vitro substrates failed to show any activity when assayed in in vivo models.
