Download or read book Porphyrin Photosensitization written by David Kessel and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods in Porphyrin Photosensitization written by David Kessel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of porphyrins for localization and photodynamic therapy of neoplastic disease has been the topic of several international symposia, reviews and books during the preceeding five years. The literature on this topic has continued to grow, as have numbers of presentations at national and international meetings relating to photobiology, chemistry, and lasers. In this volume, it is the intention of the editor to provide both information on current research projects, and detailed methodology used in such investigations. A bibliography on the subjects of porphyrin localization and therapy is included. The manuscripts contained in this volume are based on reports given at a Porphyrin Photosensitization Workshop which was held in Philadel phia, July 6-7, 1984. This Workshop was supported by NIH grant CA 36746, together with funds from the Fogarty International Center. Authors were requested to update their contributions to provide a summary of progress to mid 1985. Manuscripts containing material not presented in Philadelphia are also included, notably a series of articles describ ing current clinical and pre-clinical results from China. Since the Philadelphia Workshop, a meeting was held in Alghero, Sardinia (May, 1985), and additional conferences are now being planned; this attests to the continued interest in photodynamic therapy involving porphyrin photo sensitization.
Download or read book Photosensitisation written by Giuliana Moreno and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation induces a variety of chemical processes in biological tissues. This volume is a synthesis of up-to-the-minute reviews on such photochemical and photobiological sensitized reactions with particular relevance to photomedicine. The first part gives a description of experimental techniques for the study of the primary processes after radiation absorption by biological systems. It is followed by chapters on singlet oxygen and photomedicine, considering both phototherapy and photochemotherapy. These sections also discuss the next generation of potential photosensitizing drugs.
Download or read book Photodynamic Therapy of Neoplastic Disease written by David Kessel and published by CRC Press. This book was released on 1990-05-23 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume text provides a summary of current studies relating to the use of photosensitizing agents in the diagnosis and therapy of cancer. This interesting work describes synthesis of new sensitizers, photochemical and photobiological properties of dyes currently used for photodynamic therapy, plus those being examined with a view toward providing therapeutic advantages. It contains results and methodology from leading experts on the use of porphyrins and other photosensitizers for detection of neoplastic disease and for photodynamic therapy of neoplastic disease. The volumes focus on the major clinical and pre-clinical research groups. They also include an appended bibliography which lists all pertinent publications in this field. This easy-to-understand book is written for all workers in the field of photodynamic therapy and provides an introduction to those beginning research on some aspect of tumor photosensitization.
Download or read book Photosensitizing Compounds written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders.
Download or read book Disorders of Porphyrin Metabolism written by A. Goldberg and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each of the four authors of this book has a particular interest in disorders of porphyrin metabolism and special experience in their management. Their individual involvement in the field varies from 12 to 52 years and, combined, represents more than a century of personal experience. Since it has been written by both basic scientists and practicing physicians, the book is intended to be of value to all those involved in porphyrin metab olism and the porphyrias. It is hoped that the fascination of porphyrin metabolism and the clinical challenge of the porphyrias experienced by each of the authors will be conveyed to the readers. Michael R. Moore Kenneth E. L. McColl Claude Rimington Abraham Goldberg vii CONTENTS Color Plates ............................................ xvii 1. The History, Classification, and Incidence of the Porphyrias 1 1.1. History ........................................ 1 1.1.1. Early Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.1.2. Early Descriptions of Porphyria .............. 4 1.1.3. Biochemical Developments .................. 4 1.1.4. Acute Porphyria . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.1.5. A Complete Pathway ...................... 8 1.2. Classification of the Porphyrias . . . . . . . . . . . . . . . . . . . . . 9 1.2.1. The Current Classification. . . . . . . . . . . . . . . 12 . . . .
Download or read book Porphyrins in Tumor Phototherapy written by R. Cubeddu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the contributions of the participants to the International Symposium on Porphyrins in Tumor Phototherapy held in Bruzzano (Milano), Italy on May 26-28, 1983. The contributions are written as extended papers to provide a broad and representative coverage of the use of porphyrins in tumor phototherapy and diagnosis. In the last few years, this technique has received increasing interest for its potential applications in clinical oncology. In fact, 1,500 patients have been already treated by this therapy which has been tested in more than 100 clinical centres. Among the reported cases, a significant therapeutic effectiveness was found in some early stage cancers of lung, esophagus and stomach. The development of ·this therapy requires interdisciplinary studies from such diverse fields as physics, chemistry, biology, pharmacology, and experimental and clinical oncology. The contents of the book reflect the character of this research and deal with all the problems, from fundamental to clinical, that still require to be analysed and understood for a better evaluation 'of the potential of this therapy. The first chapter of the book deals with photophysics ?;nd.
Download or read book Toxicity Bibliography written by and published by . This book was released on 1972 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Modification of Porphyrin Porphyrinone and Benzochlorin Derivatives as Photosensitizers for Photodynamic Therapy written by Sangwan Lee and published by . This book was released on 1995 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lasers in Biology and Medicine written by F. Hillenkamp and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the lectures and seminars presented at the NATO Advanced Study Institute on Lasers in Biology and Medicine organized by the International School of Quantum Electronics at the Villa Le Pianore, Camaiore, Italy, August 19-31, 1979. Most laser applications in biology and medicine are highly interdisciplinary in nature, drawing from and pertaining to such diverse fields as the physical sciences ( (bio)physics, (bio)chemi stry) , engineering, the biological sciences (cellular research, photobiology) and finally theoretical and clinical medicine. Indeed the group of participants of the summer school did reflect this diversity both in background and interest. The presentations con tained in this volume mainly fall into two categories: tutorial lectures on the most important general subjects, intended to lay a common base for all participants, and a number of more advanced con tributions, serving the purpose of exemplifying selected but typical applications in their current state of development. Intense inter communication, lively discussion, and here and there even future cooperation were the general aims more than a detailed in-depth discussion of one or the other aspect of this large field. In this sense it is the hope of the organizing committee that, despite the inevitable limitations, a broad and reasonably representative cov erage of the field has been achieved and that this volume may be a valuable aid for newcomers to get a good start into this complex subject area for some years to corne.
Download or read book The Science of Photobiology written by Kendric C. Smith and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of The Science of Photobiology was published in 1977, and was the first textbook to cover all of the major areas of photobiology. The science of photobiology is currently divided into 14 subspecialty areas by the American Society for Photobiology. In this edition, however, the topics of phototechnology and spectroscopy have been com bined in a new chapter entitled "Photophysics." The other subspecialty areas remain the same, i.e., Photochemistry, Photosensitization, UV Radiation Effects, Environmental Photobiology, Photomedicine, Circadian Rhythms, Extraretinal Photoreception, Vision, Photomorphogenesis, Photomovement, Photosynthesis, and Bioluminescence. This book has been written as a textbook to introduce the science of photobiology to advanced undergraduate and graduate students. The chapters are written to provide a broad overview of each topic. They are designed to contain the amount of information that might be presented in a one-to two-hour general lecture. The references are not meant to be exhaustive, but key references are included to give students an entry into the literature. Frequently a more recent reference that reviews the literature will be cited rather than the first paper by the author making the original discovery. The chapters are not meant to be a repository of facts for research workers in the field, but rather are concerned with demon strating the importance of each specialty area of photobiology, and documenting its relevance to current and/or future problems of man.
Download or read book Photophysiology written by Arthur C. Giese and published by Elsevier. This book was released on 2013-09-25 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photophysiology: Current Topics in Photobiology and Photochemistry, Volume VI is a collection of papers that discusses photobiological phenomena found on cells of organisms. The papers in this collection deal with specialized areas of photobiology. One paper describes the instruments used in measuring the course of chlorophyll fluorescence in vivo that occurs when a chlorophyll molecule, stimulated by a light source, returns to its ground state from a previous first singlet state, resulting in a light emission lasting for a few nanoseconds. Another paper discusses the mechanism of light-induced carotenoid synthesis in nonphotosynthetic plants, including temperature-independent photochemical reactions, which results in the organism's producing carotenoids on subsequent incubations in darkness. One paper also explains photosensitization observed in mutant cells resulting from exposure to specific wavelength of light in the presence of a natural sensitizer. This paper points out that there are four main groups of photosensitizers, namely, the hypericins, chlorophylls, porphyrins, and psoralens. This book can prove valuable for cell biologists, micro-biologists, students, and researchers involved in the fields of photobiology and photochemistry.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Photodynamic Therapy written by Thierry Patrice and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, light has been used to cure various diseases. However, it is only recently that a new medical field has arisen. Photodynamic therapy (PDT), also known as photochemotherapy, is a fast growing technique which was initially devoted to cancer care but which is now recognised as a promising treatment technique in a variety of clinical fields. Written by recognised experts, Photodynamic Therapy provides a comprehensive explanation of what PDT is and how it has developed as a technique in areas such as the detection of lung cancer and applications in dermatology, gynaecology and neurosurgery. This book is ideal both as an introduction to PDT and as an informative text for those wishing to expand their knowledge. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find it an invaluable source of information.
Download or read book Primary Photo Processes in Biology and Medicine written by R. V. Bensasson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently there have been major developments in the experimental techniques available for the study of the primary events following the absorption of ultra-violet and visible radiation by biological systems. These techniques, which include absorption, emission, resonance Raman, electron spin resonance, nuclear magnetic resonance and photoacoustic spectroscopies, can be used to study the fate of transient species with lifetimes ranging from seconds to nanoseconds and extending in some cases, such as laser flash photolysis, to pico 12 15 (10- S)- and even femtoseconds (10- s). In parallel with these developments there has been a dramatic increase in the use of light in medicine via the direct photochemical alteration of endogenous molecules (phototherapy) or via the photoactivation of drugs in the skin or other tissue (photochemotherapy). Thus neonatal hyperbili rubinaemia can be routinely treated by phototherapy and psoriasis is frequently treated by PUVA photochemotherapy. A promising new photo chemotherapy used the phototoxicity of porphyrin drugs activated by red light to destroy solid malignant tumors. While some of the overall qualitative effects of such treatments are known, only recently have we begun to understand the associated molecular mechanisms. The primary molecular processes involve short-lived species. The pur pose of this Advanced Study Institute was to review some newer experi mental techniques for the study of such species, the application of these techniques to biological and medical systems and to examine the value of such information in phototherapeutic situations.
Download or read book Photodynamic Medicine written by Herwig Kostron and published by Royal Society of Chemistry. This book was released on 2016 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Series in Photochemical and Photobiological Sciences. Photodynamic therapy (PDT) is increasingly being used amongst health practitioners in combating a variety of disease. This book reviews the current state of development of PDT, and also presents the foreseeable advancements of the field in the next decade. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find this book an invaluable source of information. Chapters are drawn from research discusses at the 10th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice in Brixen and are written and edited by leaders in the field. Mirroring the philosophy of that meeting, this book contains an informative balance of the basic sciences and clinical applications of PDT. Following an introduction to PDT, its history, and how techniques have developed, chapter serve as a practical guide for practitioners, covering topics such as sensitizer dosage and light dosage, and examples of relevant studies. The text goes further tp explore areas outside the medical field, such as the impact of PDT on society and the environment, and the economics of therapies. This book is dedicated to the memory of Professor Giulio Jori, and expert in this field, who sadly passed away on the 23rd December 2014.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1983 with total page 1442 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
