Download or read book Adverse Events Associated with Childhood Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 1993-01-01 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.
Download or read book The Cutter Incident written by Paul A. Offit and published by Yale University Press. This book was released on 2007-09-18 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Download or read book Polio written by Thomas Abraham and published by Oxford University Press. This book was released on 2018-09-01 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.
Download or read book Vaccinating Britain written by Gareth Millward and published by Manchester University Press. This book was released on 2019-01-29 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This electronic version has been made available under a Creative Commons (BY-NC-ND) open access license. This book is available as an open access ebook under a CC-BY-NC-ND licence. Vaccinating Britain shows how the British public has played a central role in the development of vaccination policy since the Second World War. It explores the relationship between the public and public health through five key vaccines – diphtheria, smallpox, poliomyelitis, whooping cough and measles-mumps-rubella (MMR). It reveals that while the British public has embraced vaccination as a safe, effective and cost-efficient form of preventative medicine, demand for vaccination and trust in the authorities that provide it has ebbed and flowed according to historical circumstances. It is the first book to offer a long-term perspective on vaccination across different vaccine types. This history provides context for students and researchers interested in present-day controversies surrounding public health immunisation programmes. Historians of the post-war British welfare state will find valuable insight into changing public attitudes towards institutions of government and vice versa.
Download or read book Splendid Solution written by Jeffrey Kluger and published by Penguin. This book was released on 2006-02-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The compelling true story of Dr. Jonas Salk's quest to develop a vaccine for polio. In 1916, the United States was hit with one of the worst polio epidemics in history. The disease was a terrifying enigma: striking out of nowhere, it afflicted tens of thousands of children and left them—literally overnight—paralyzed. Others it simply killed. At the same time, a child named Jonas Salk was born.... When Franklin Delano Roosevelt was diagnosed with polio shortly before assuming the Presidency, Salk was given an impetus to study this deadly illness. After assisting in the creation of an influenza vaccine, Salk took up the challenge. His progress in combating the virus was hindered by the politics of medicine and by a rival researcher determined to discredit his proposed solution. But Salk's perseverance made history—and for close to seventy years his vaccine has saved countless lives, bringing humanity close to eradicating polio throughout the world. Splendid Solution chronicles Dr. Salk's race against time to achieve an unparalleled breakthrough that made him a cultural hero and icon of modern medicine.
Download or read book Polio Across the Iron Curtain written by Dóra Vargha and published by Cambridge University Press. This book was released on 2018-11 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through the lens of polio, Dóra Vargha looks anew at international health, communism and Cold War politics. This title is also available as Open Access.
Download or read book Nemesis written by Philip Roth and published by Vintage. This book was released on 2011-10-04 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • Set in a close-knit Newark neighborhood during a terrifying polio outbreak in 1944, a “book [that] has the elegance of a fable and the tragic inevitability of a Greek drama” (The New Yorker)—from the Pulitzer Prize–winning author of American Pastoral. Bucky Cantor is a vigorous, dutiful twenty-three-year-old playground director during the summer of 1944. A javelin thrower and weightlifter, he is disappointed with himself because his weak eyes have excluded him from serving in the war alongside his contemporaries. As the devastating disease begins to ravage Bucky’s playground, Roth leads us through every inch of emotion such a pestilence can breed: fear, panic, anger, bewilderment, suffering, and pain. Moving between the streets of Newark and a pristine summer camp high in the Poconos, Nemesis tenderly and startlingly depicts Cantor’s passage into personal disaster, the condition of childhood, and the painful effect that the wartime polio epidemic has on a closely-knit, family-oriented Newark community and its children.
Download or read book Polio written by Thomas Abraham and published by Oxford University Press. This book was released on 2018-09-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.
Download or read book Netter s Neurology written by H. Royden Jones and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Visually rich Netter artwork and detailed yet concise text provide you with an overview of general neurology and its intersection with internal medicine, neurosurgery, ophthalmology, psychiatry, and orthopedics.
Download or read book Viral Gastroenteritis written by Shunzo Chiba and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, rapid developments have occurred in the field of viral gastroenteritis. This book is an update of fundamental and practical aspects of viral gastroenteritis. Among the various agents that cause viral gastroenteritis, group A rotaviruses and caliciviruses are the focus of this volume because of their clinical impact and the significance of new findings about them.
Download or read book Post polio Syndrome written by Julie K. Silver and published by . This book was released on 2001 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effects of polio that occur decades after the disease has run its course -- weakness, fatigue, pain, intolerance to cold, difficulty with breathing and swallowing -- are often more devastating than the original disease. This book on the diagnosis and management of polio-related health problems is an essential resource for polio survivors and their families and health care providers. Dr. Julie K. Silver, who has both personal and professional experience with post-polio syndrome, begins the book by defining and describing PPS and providing a historical overview of its diagnosis and treatment. Chapters that follow discuss finding good medical care, dealing with symptoms, maintaining proper nutrition and weight, preventing osteoporosis and falls, and sustaining mobility. Dr. Silver reviews the latest in braces, shoes, assistive devices, and wheelchairs and scooters. She also explores issues involving managing pain, surgery, complementary and alternative medicine, safe and comfortable living environments, insurance and disability, and sex and intimacy.
Download or read book Current Literature Poliomyelitis and Related Diseases written by and published by . This book was released on 1961 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Global Epidemiology of Infectious Diseases written by Alan D. Lopez and published by . This book was released on 2004 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This fourth volume of the Global Burden of Disease and Injuries Series provides the reader with information on the epidemiology and burden of major infectious and parasitic diseases. As with previous volumes of the Global Burden of Disease study, the chapters in this book detail the situation as experienced in the year 1990. Since then the epidemiology of some of the conditions described has changed, and where this is the case the authors have added a brief paragraph acknowledging this. The chapters therefore do not provide a detailed update on the current burden of disease, which is accommodated in the documentation of the Global Burden of Disease 2000 and published elsewhere."--Preface.
Download or read book The Epidemiology of Polio in Israel written by Tiberio A. Swartz and published by . This book was released on 2008 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chasing Polio in Pakistan written by Svea Closser and published by Vanderbilt University Press. This book was released on 2010-08-16 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: From remote villages and nomadic encampments to World Health Organization headquarters, a vivid ethnography of the Global Polio Eradication Initiative
Download or read book Antibody Fc written by Margaret Ackerman and published by Academic Press. This book was released on 2013-08-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. - Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro - Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies - Color illustrations enhance explanations of the immune system
