Download or read book A Practical Guide to Designing Phase II Trials in Oncology written by Sarah R. Brown and published by John Wiley & Sons. This book was released on 2014-03-28 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given. A Practical Guide to Designing Phase II Trials in Oncology: Offers a structured and practical approach to phase II trial design Considers trial design from both an academic and industry perspective Includes a structured library of available phase II trial designs Is relevant to both clinical and statistical researchers at all levels Includes real life examples of applying this approach For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.

Download or read book Commodities written by M. A. H. Dempster and published by CRC Press. This book was released on 2022-12-09 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since a major source of income for many countries comes from exporting commodities, price discovery and information transmission between commodity futures markets are key issues for continued economic development. Commodities: Fundamental Theory of Futures, Forwards, and Derivatives Pricing, Second Edition covers the fundamental theory of and derivatives pricing for major commodity markets, as well as the interaction between commodity prices, the real economy, and other financial markets. After a thoroughly updated and extensive theoretical and practical introduction, this new edition of the book is divided into five parts – the fifth of which is entirely new material covering cutting-edge developments. Oil Products considers the structural changes in the demand and supply for hedging services that are increasingly determining the price of oil Other Commodities examines markets related to agricultural commodities, including natural gas, wine, soybeans, corn, gold, silver, copper, and other metals Commodity Prices and Financial Markets investigates the contemporary aspects of the financialization of commodities, including stocks, bonds, futures, currency markets, index products, and exchange traded funds Electricity Markets supplies an overview of the current and future modelling of electricity markets Contemporary Topics discuss rough volatility, order book trading, cryptocurrencies, text mining for price dynamics and flash crashes

Download or read book Head and Neck Cancer written by Jacques Bernier and published by Springer Science & Business Media. This book was released on 2011-06-15 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.

Download or read book Proceedings in Finance and Risk Perspectives 12 written by and published by Othmar M. Lehner. This book was released on with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Integrated View of the Molecular Recognition and Toxinology written by Gandhi Radis-Baptista and published by BoD – Books on Demand. This book was released on 2013-07-01 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Toxinology has been consolidated as a scientific area focused on the intertwined description of several aspects of animal toxins. In an inquiring biotechnological world, animal toxins appear as an invaluable source for the discovery of therapeutic polypeptides. Animal toxins rely on specific chemical interactions with their partner molecule to exert their biological actions. The comprehension of how molecules interact and recognize their target is essential for the rational exploration of bioactive polypeptides as therapeutics. Investigation on the mechanism of molecular interaction and recognition offers a window of opportunity for the pharmaceutical industry and clinical medicine. Thus, this book brings examples of two interconnected themes - molecular recognition and toxinology concerning to the integration between analytical procedures and biomedical applications.

Download or read book Handbook of Evidence Based Radiation Oncology written by Eric Hansen and published by Springer Science & Business Media. This book was released on 2010-06-17 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of this book's first edition, Dr. Eric Hansen and Dr. Mack Roach have updated, revised, and expanded the Handbook of Evidence-based Radiation Oncology, a portable reference that utilizes evidence-based medicine as the basis for practical treatment recommendations and guidelines. Organized by body site, concise clinical chapters provide easy access to critical information. Important "pearls" of epidemiology, anatomy, pathology, and clinical presentation are highlighted. Key facets of the work-up are listed, followed by staging and/or risk classification systems. Treatment recommendations are discussed based on stage, histology, and/or risk classification. Brief summaries of key trials and studies provide rationale for the recommendations. Practical guidelines for radiation techniques are described. Finally, complications and follow-up guidelines are outlined. Updates from the first edition include brand new color figures and color contouring mini-atlases for head and neck, gastrointestinal, prostate, and gynecological tumors; redesigned tables for increased readability; new chapters on management of the neck and unknown primary, clinical radiobiology, and pediatric malignancies and benign conditions; and new appendices including the American College of Radiology guidelines for administration of IV contrast.

Download or read book Principles and Practice of Lung Cancer written by Harvey I. Pass and published by Lippincott Williams & Wilkins. This book was released on 2012-02-13 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.

Download or read book Gynaecology E Book written by Robert W. Shaw and published by Elsevier Health Sciences. This book was released on 2010-10-01 with total page 1085 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long recognized as the standard general reference work providing a complete overview of contemporary gynaecological practice, this new edition of Shaw, Gynaecology provides all the information that trainees need to master in order to successfully take their professional certification exams as well as providingthe practicing gynaecologist with an accessible overview of the "state of play" of diagnostic and therapeutic procedures. Totally rewritten, it gives a succinct but comprehensive account of all currently available resources in the management of gynaecological disorders. Comprehensive overview of contemporary gynaecological practice with a clinically focused approach. It covers all of the areas that a gynaecologist covers on a day-to-day basis and helps in the formulation and implementation of the most effective treatment. Details the use of various imaging modalities and investigative techniques as they relate to specific diseases in order to provide a solid foundation for clinical practice. User-friendly features such as chapter outlines, summary tables, key point boxes incorporated throughout.Provides quick access to the most necessary information for practitioners needing a quick consult or trainees preparing for exams. Copiously illustrations clarify and enhance the text whenever appropriate. Highly selective and current list of references quickly directs the reader to further investigations. New full colour illustrations incorporated throughout to accurately depict the full range of both common and rare disorders. Details up-to-date investigative and minimally invasive therapeutic techniques to keep the user abreast of the latest diagnostic and management options. Enhanced emphasis on surgical outcomes to help the user select the most appropriate procedure for any given patient. Two brand new editors and many brand new contributors provide a fresh perspectives on gynaecological oncology, reproductive and urogynaecological conditions.

Download or read book Last Alarm written by Thomas A. Woodley and published by iUniverse. This book was released on 2022-12-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Last Alarm: The Charleston 9 is the heart-wrenching story of how nine brave firefighters died battling the 2007 Sofa Super Store fire in Charleston, South Carolina. Life-endangering conditions combined together to create a ‘perfect firestorm’ ---a fuel-ladened furniture store that was a time bomb and death trap, and a fire department at the time that was understaffed, ill-equipped, and far below national fire service standards. The author, Thomas A. Woodley, a labor litigation lawyer who represented many firefighters and emergency medical workers for over forty years, provides a factbased account of the multiple alarm response to the biggest structure fire in Charleston in 150 years. Thorough investigations and well documented reports issued by federal agencies and a review team of outside experts, plus firefighter interviews and media articles, enabled the author to accumulate a wealth of material to shed insights on one of the deadliest fires in recent memory.

Download or read book Abeloff s Clinical Oncology E Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2019-01-08 with total page 2648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. - Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. - Features extensive updates including the latest clinical practice guidelines, decision-making algorithms, and clinical trial implications, as well as new content on precision medicine, genetics, and PET/CT imaging. - Includes revised diagnostic and treatment protocols for medical management, surgical considerations, and radiation oncology therapies, stressing a multispecialty, integrated approach to care. - Helps you find information quickly with updated indexing related to management recommendations, focused fact summaries, updated key points at the beginning of each chapter ideal for quick reference and board review, and algorithms for patient evaluation, diagnosis, and treatment options. - Offers more patient care coverage in disease chapters, plus new information on cancer as a chronic illness and cancer survivorship. - Discusses today's key topics such as immuno-oncology, functional imaging, precision medicine, the application of genetics in pathologic diagnosis and sub-categorization of tumors as well as the association of chronic infectious diseases such as HIV and cancer. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Download or read book Controversies in the Management of Gynecological Cancers written by Jonathan A. Ledermann and published by Springer Science & Business Media. This book was released on 2013-12-13 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a novel text that highlights the controversial areas in the management of gynecological cancers. None of the topics in this book have definitive answers; they represent the everyday decision-making facing gynecologists, oncologists, radiologists, pathologists and other health professionals treating women with these conditions. This book is not to be used as a traditional textbook; it is a text that specialists and trainees will use to help them weigh up the arguments that exist in a variety of areas in the treatment of gynecological cancers. Each chapter will have two or more authors, selected either for their opposing views or for their ability to provide an opposite view or opinion to the other. The content will be evidence-based, illustrating contrasting evidence and scientific opinion in the literature. Each chapter will close on a summary indicating the direction of research needed to address the issues being discussed.

Download or read book Guide to U S Department of Education Programs 2009 written by Kate Devine and published by DIANE Publishing. This book was released on 2010-11 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clinical Guide to Transplantation in Lymphoma written by Bipin N. Savani and published by John Wiley & Sons. This book was released on 2015-08-17 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book on clinical guide to transplantation in lymphoma to present cutting edge knowledge on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies Provides practical management guidance on how to integrate, transplantation and novel therapies in patients with lymphoid malignancies Covers an overview of transplantation in lymphoma, and management of the lymphoid malignancies Discusses organizational aspects of transplant patients and managing a transplant program Appendices provide practical quick-reference information on follow-up after autologous and allogenic stem cell transplantation in lymphoma

Download or read book Veterinary Toxicology written by Ramesh C Gupta and published by Academic Press. This book was released on 2018-02-06 with total page 1239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists. - Provides a complete, up-to-date, integrated source of information on toxins and poisons relating to animals - Covers all important aspects of veterinary toxicology with completely updated and revised chapters - Includes basic principles of a key toxicology concept, along with clinical applications and a list of major references for further reading

Download or read book Public Support of Innovation in Entrepreneurial Firms written by Albert N. Link and published by Edward Elgar Publishing. This book was released on 2013-12-27 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on data collected by the National Research Council of the National Academies of the United States on projects funded through the SBIR program, these papers form a comprehensive foundation that will serve as a critical guide to the topic for both

Download or read book Blumgart s Surgery of the Liver Biliary Tract and Pancreas 2 Volume Set E Book written by William R. Jarnagin and published by Elsevier Health Sciences. This book was released on 2022-09-13 with total page 2486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Balancing basic science with information on everyday clinical practice, Blumgart's Surgery of the Liver, Biliary Tract and Pancreas, 7th Edition, provides you with expert guidance and advances in the field so you can offer patients the most optimal diagnostic and surgical care. In two convenient volumes, Dr. William Jarnagin and his team of internationally recognized surgeons cover exactly what you need to know, including advances in diagnostic and surgical techniques, minimally invasive surgeries, new interventional diagnostic techniques, and all relevant diseases. This comprehensive, practical reference is designed to help you choose and perform the most appropriate procedures that will minimize inpatient hospital time, curtail costs, and reduce overall recovery time for your patients. - Presents cutting-edge guidance on pathology, diagnostics, surgery and non-operative intervention of the liver, biliary tract, and pancreas in one highly regarded, authoritative reference. - Covers all surgical approaches, both open and minimally invasive. - Considers all worldwide opinions and approaches to management, and includes key data on surgical outcomes to better inform clinical decision-making. - Contains 161 chapters with updated references and additional figures—more than 1,500 illustrations in all. The imaging section has been reorganized to reflect a disease-based approach. - Includes new and expanded sections on advances in molecular characterization of benign and malignant HPB diseases, perioperative management, interventional techniques, minimally invasive surgery and robotics, and therapeutic advances for malignant disease. - Features a section dedicated entirely to operative technique, plus a new historical chapter authored by Professor Jacques Belghitti: "Hepatobiliary and Pancreatic Surgery: Historical Perspective.

Download or read book Thoracic Malignancies written by Steven E. Schild, MD and published by Demos Medical Publishing. This book was released on 2010-03-08 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoracic Malignancies: Thoracic Malignancies is the first title in Radiation Medicine Rounds. These tumors take more lives than any others and they are among the most preventable of tumors. Thus it is crucial for the practitioner to be up-to-date on the latest insights regarding their management. Thoracic Malignancies addresses the multi-disciplinary nature of the care of these tumors. There is representation from radiation oncology, medical oncology, and surgery ensuring a well-rounded summarization of current practice. Included are chapters on lung cancer, esophageal cancer, and thymomas providing coverage of the vast majority of thoracic tumors. The multi-disciplinary nature of the articles provides readers with an up-to-date summary and a well-rounded review regarding these tumors and their care. Expert authors provide reviews and assessments of the most recent data and its implications for current clinical practice, along with insights into emerging new trends of importance for the near future. About the Series Radiation Medicine Rounds is an invited review publication providing a thorough analysis of new scientific, technologic, and clinical advances in all areas of radiation medicine. There is an emphasis throughout on multidisciplinary approaches to the specialty, as well as on quality and outcomes analysis. Published three times a year Radiation Medicine Rounds provides authoritative, thorough assessments of a wide range of Ïhot topicsÓ and emerging new data for the entire specialty of radiation medicine. Features of Radiation Medicine Rounds include: Editorial board of nationally recognized experts across the spectrum of radiation medicine In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Radiation Medicine Issues edited by an authority in specific subject area Focuses on major topics in Radiation Medicine with in-depth articles covering advances in radiation science radiation medicine technology, radiation medicine practice, and assessment of recent quality and outcomes studies Emphasizes multidisciplinary approaches to research and practice