Download or read book Pharmaceutical Applications of Supramolecules written by Nidhi Goel and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines the use of supramolecules as different pharmaceutical drugs. Supramolecular chemistry in pharmaceutical sciences is quite a young and rapidly developing field. Supramolecular assemblies might offer an alternative for existing pharmaceutical formulations, as they facilitate the improvement of physicochemical and pharmacological properties i.e., higher bioavailability, better biocompatibility and drug-targeting, fewer multidrug-resistances. This book offers an overview of the recent advances in supramolecular structures and discusses the future aspects and challenges related to the development of these molecules, providing also a perspective on how to overcome these issues. Divided into 13 chapters contributed by experts in their field, the book provides a deeper understanding of intermolecular forces playing pivotal roles in mediating the interactions between chemical molecules and biological systems by focusing on different applications of supramolecular compounds. In this book, readers will find valuable insights into the preparation of supramolecules and the latest research and development trends of supramolecules as anticancer drugs, including liquid-crystalline supramolecular assemblies, and as antimicrobial, antiviral, anti-inflammatory and cardiovascular drugs. Particular attention is given to the application of supramolecules in the fields of biomedicine, bioimaging, and vaccine development. Given its breadth, this book will appeal to a wide readership from researchers and students interested in these fields to professionals in the pharma industry.
Download or read book Pharmaceutical Applications of Supramolecules written by Nidhi Goel and published by Springer Nature. This book was released on 2023-01-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines the use of supramolecules as different pharmaceutical drugs. Supramolecular chemistry in pharmaceutical sciences is quite a young and rapidly developing field. Supramolecular assemblies might offer an alternative for existing pharmaceutical formulations, as they facilitate the improvement of physicochemical and pharmacological properties i.e., higher bioavailability, better biocompatibility and drug-targeting, fewer multidrug-resistances. This book offers an overview of the recent advances in supramolecular structures and discusses the future aspects and challenges related to the development of these molecules, providing also a perspective on how to overcome these issues. Divided into 13 chapters contributed by experts in their field, the book provides a deeper understanding of intermolecular forces playing pivotal roles in mediating the interactions between chemical molecules and biological systems by focusing on different applications of supramolecular compounds. In this book, readers will find valuable insights into the preparation of supramolecules and the latest research and development trends of supramolecules as anticancer drugs, including liquid-crystalline supramolecular assemblies, and as antimicrobial, antiviral, anti-inflammatory and cardiovascular drugs. Particular attention is given to the application of supramolecules in the fields of biomedicine, bioimaging, and vaccine development. Given its breadth, this book will appeal to a wide readership from researchers and students interested in these fields to professionals in the pharma industry.
Download or read book Supramolecular Nanomaterials for Engineering Drug Delivery and Medical Applications written by Yohann Corvis and published by Frontiers Media SA. This book was released on 2021-01-21 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Supramolecular Chemistry written by Peter J. Cragg and published by Springer Science & Business Media. This book was released on 2010-08-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.
Download or read book Supramolecular Systems in Biomedical Fields written by Hans-Jorg Schneider and published by Royal Society of Chemistry. This book was released on 2013-09-06 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.
Download or read book Applications of Supramolecular Chemistry written by Hans-Jorg Schneider and published by CRC Press. This book was released on 2012-03-28 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Supramolecular Chemistry introduces the use of non-covalent interactions and molecular recognition for many fields. Applications include the analysis of technically, medically, and environmentally important chemical compounds, their separation, purification and removal, and the design of new materials, including supramolecular elect
Download or read book Bioconjugated Materials Part 2 Applications in Drug delivery Vaccine formulations and Important conjugates for cancer therapy written by and published by Elsevier. This book was released on 2023-11-03 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Comprehensive Analytical Chemistry series - Updated release includes the latest information on Isotope Dilution
Download or read book Chemistry and Biological Activity of Steroids written by Jorge António Ribeiro Salvador and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
Download or read book Introduction to Supramolecular Chemistry written by Helena Dodziuk and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new rapidly progressing field on the crossroads among chemistry, biochemistry, physics and technology - supramolecular chemistry - has just emerged. You have to be involved, to know what's going on in this domain and to take part in the development. This book will show you in a condensed form exciting phenomena unthinkable within the realm of classical organic chemistry (for example, alkali metal anions or cyclobutadiene stable for month at room temperature) that not only provide the basis for revolutionizing numerous branches of industry but also improve our understanding of the functioning of living organisms and of the origin of life. Designing supramolecular systems with desired properties will among others make chemical industry cleaner and more safe, electronics smaller by developing devices composed of single molecule or molecular aggregate. It will also entirely change the way we use energy resources. In addition, it will also transform the pharmaceutical industry and medicine by developing new ways of drugs administration and new composite biocompatible materials which will serve as implants of new generation changing dentistry, surgery, and other branches of medicine. You cannot afford to stand apart. With its brief but comprehensive and vivid presentation including the latest development, Introduction to Supramolecular Chemistry is the best method to get into this domain. This book provides an excellent summary of information scattered across the literature. The brief but comprehensive coverage of the whole field including practically all important group of compounds forming aggregates (in particular crown ethers, cavitands, fullerenes, cyclodextrins and their complexes) provisioning full references for the discussed subjects make this book of value not only for Ph.D. students and non-specialists in this domain but also for those working in the field. The book has been found to be a particularly useful resource for students and more generally for those wanting to get the up-to-date concise account of this exciting field.
Download or read book Supramolecular Chemistry of Small Molecular Fundamentals to Drug receptor Applications written by Dhanushi Thathsara Welideniya and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A family of bis-pyridine based pharmaceutical active ingredients were synthesized and co-crystallized with four iodoperfluoroalkanes. Thirteen new crystal structures that are driven by I···N(py) halogen bonds, are presented and compared with that of their hydrogen-bonded analogues. Halogen bonded co-crystals exhibit two different structural arrangements, as opposed to layered architectures observed in hydrogen bonded co-crystals. In order to explore the effect of aromatic stacking interactions on hydrogen and halogen bond driven co-crystallization process, we utilized a series of aromatic hydrogen and halogen bond donors in combination with bis-pyridine based pharmaceutical active ingredients. Aromatic stacking between the donor and the acceptor were limited, due to the lack of complementarity between the donor and the acceptor in terms of size, shape and geometry. In that case, homomeric interactions between the single components were translated into the structure of the binary co-crystals. According to our charge calculations, similarly activated hydrogen and iodine atoms possess similar electrostatics. Therefore, we wanted to investigate the interchangeability of hydrogen bonds and halogen bonds by utilizing 2-aminopyrimidine as the backbone for C(sp)-H and C(sp)-I functionalities which makes self-complementary ribbons via NH···N synthons. Our results show that the ethynyl proton is capable of acting as a synthon mimic of ethynyl iodine by interchangeable C(sp)-H···N hydrogen bonds and C(sp)-I···N halogen bonds. We exploited the halogen bonding donor capability of iodo, bromo and chloro ethynyl functionalities towards a series of halide ions. Based on the grinding experiments these donors showed 90%, 70% and 50% success rates towards halides. Among the halides, chlorides exhibited the highest red shift compared to bromides and iodides. We synthesized a series of cavitands functionalized with hydrogen bond donor and acceptor groups and studied their binding preferences towards a series of active ingredients. We have shown that suitably functionalized cavitands can act as carriers of active ingredients and especially, selective binding of aspirin is demonstrated using a two-point binding mode.
Download or read book Separations and Reactions in Organic Supramolecular Chemistry written by Fumio Toda and published by John Wiley & Sons. This book was released on 2004-04-21 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new volume in the "Perspectives in Supramolecular Chemistry" series focusing on separating supramolecular structures, a key step in supramolecular chemistry. Two guest editors have been at the forefront of the development of chromatographical methods to deal with supramolecular systems. Reactions of supramolecular structures show the way into the future of chemistry. Fumio Toda is one of the driving forces in the development of supramolecular separation systems. A practical title in the prestigious “Perspectives in Supramolecular Chemistry” series.
Download or read book Core Concepts in Supramolecular Chemistry and Nanochemistry written by Jonathan W. Steed and published by John Wiley & Sons. This book was released on 2007-04-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry and nanochemistry are two strongly interrelated cutting edge frontiers in research in the chemical sciences. The results of recent work in the area are now an increasing part of modern degree courses and hugely important to researchers. Core Concepts in Supramolecular Chemistry and Nanochemistry clearly outlines the fundamentals that underlie supramolecular chemistry and nanochemistry and takes an umbrella view of the whole area. This concise textbook traces the fascinating modern practice of the chemistry of the non-covalent bond from its fundamental origins through to it expression in the emergence of nanochemistry. Fusing synthetic materials and supramolecular chemistry with crystal engineering and the emerging principles of nanotechnology, the book is an ideal introduction to current chemical thought for researchers and a superb resource for students entering these exciting areas for the first time. The book builds from first principles rather than adopting a review style and includes key references to guide the reader through influential work. supplementary website featuring powerpoint slides of the figures in the book further references in each chapter builds from first principles rather than adopting a review style includes chapter on nanochemistry clear diagrams to highlight basic principles
Download or read book Biomaterial based Hydrogels written by Sougata Jana and published by Springer Nature. This book was released on with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gels Handbook Fundamentals Properties Applications In 3 Volumes written by and published by World Scientific. This book was released on 2016-01-25 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels are made from a three-dimensional network of cross linked hydrophilic polymers or colloidal particles that contain a large fraction of water. In recent years, hydrogels have attracted significant attention for a variety of applications in biology and medicine. This has resulted in significant advances in the design and engineering of hydrogels to meet the needs of these applications. This handbook explores significant development of hydrogels from characterization and applications. Volume 1 covers state-of-art knowledge and techniques of fundamental aspects of hydrogel physics and chemistry with an eye on bioengineering applications. Volume 2 explores the use of hydrogels in the interdisciplinary field of tissue engineering. Lastly volume 3 focuses on two important aspects of hydrogels, that is, drug delivery and biosensing. Contains 50 colour pages.
Download or read book Cyclodextrins written by Sahar Amiri and published by John Wiley & Sons. This book was released on 2017-08-30 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comprehensive resource for understanding the structure, properties, and applications of cyclodextrins Cyclodextrins: Properties and Industrial Applications is a comprehensive resource that includes information on cyclodextrins (CDs) structure, their properties, formation of inclusion complex with various compounds as well as their applications. The authors Sahar Amiri and Sanam Amiri, noted experts in the field of cyclodextrins, cover both the basic and applied science in chemistry, biology, and physics of CDs and offers scientists and engineers an understand of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides consisting of (α-1,4)-linked α-D-glucopyranose units. The formation of inclusion complex between CDs as host and guest molecules is based on non-covalent interaction such as hydrogen bonding or van der waals interactions and lead to the formation of supramolecular structures. These supramolecular structures can be used as macroinitiator for initiating various type of reactions. CDs are widely used in many industrial products such as pharmacy, food and flavours, chemistry, chromatography, catalysis, biotechnology, agriculture, cosmetics, hygiene, medicine, textiles, drug delivery, packing, separation processes, environment protection, fermentation, and catalysis. This important resource: Offers a basic understanding of cyclodextrins for researchers and engineers Includes information of the basic structure of cyclodextrins and their properties Reviews how cyclodextrins can be applied in a variety of fields including medicine, chemistry, textiles, packing, and many others Shows how encapsulate corrosion inhibitors became active in corrosive electrolytes to ensure delivery of the inhibitors to corrosion sites and long-term corrosion protection Cyclodextrins offers research scientists and engineers a wealth of information about CDs with particular focus on how cyclodextrins are applied in various ways including in drug delivery, the food industry, and many other areas.
Download or read book Smart Micro and Nanomaterials for Pharmaceutical Applications written by Ajit Behera and published by CRC Press. This book was released on 2024-08-27 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control. This approach has several advantages, including maximizing the therapeutic effects of a drug while minimizing side effects. This book presents various stimuli-responsive micro- and nanomaterials for pharmaceutical industries. This volume: Covers the global market perspective of micro- and nano-smart materials in pharmaceutical industries. Details various processing routes. Discusses mechanisms for target release. Addresses applications in oral drug delivery, anticancer agents, anti-tumor drug delivery, and drugs for management of infection. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.
Download or read book Supramolecular Chemistry Fundamentals and Applications written by Katsuhiko Ariga and published by Springer Science & Business Media. This book was released on 2006-08-02 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamentals of "supramolecular chemistry" to the latest developments on the subject are covered by this book. It sets out to explain the topic in a relatively easy way. The basic concepts of molecular recognition chemistry are included. Molecules with fascinating shapes and functions such as fullerenes, carbon nanotubes, dendrimers, rotaxane, and catenane, and molecular assemblies are also explained. Thereafter applications of supermolecules to nanotechnology are introduced with many examples of molecular devices. The last part of the book describes biological supermolecules and their mimics. Though simply explained undergraduate and graduate students in Chemistry will be able to use aspects of this work as an advanced textbook.
