Download or read book Perinatal Programming written by Deborah Hodgson and published by CRC Press. This book was released on 2005-12-20 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal factors are critical in the 'programming' of behavioral, endocrine and immunologic outcomes of adult life. Exposure to many factors in utero can drive fetal development along specific trajectories. Perinatal factors can also affect many diverse systems that have significant implications for long-term health outcomes. The findings from basic research are so diverse and suggest implications in many different arenas. Bringing together these findings, this book explores the evidence linking the role of early life events to long-term physical and psychological health outcomes. It pulls the research together and communicates the findings to the wider scientific and clinical communities.

Download or read book Perinatal Programming written by Andreas Plagemann and published by Walter de Gruyter. This book was released on 2011-11-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal Programming addresses the environment-dependent setting of fundamental life functions and dispositions for diseases in developmental periods during pregnancy and in early infancy. It provides a new view of the origins of health and diseases. To realize these associations may enable us to prevent diseases for the long term. This book reviews actual state-of-the-art knowledge in the perinatal programming field. The authors are internationally known scientists of this research area.

Download or read book Perinatal Programming of Neurodevelopment written by Marta C. Antonelli and published by Springer. This book was released on 2014-10-06 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of the brain and nervous system is shaped not just by a genetic program, but also by the effects of multiple environmental stimuli. There are currently no book-length treatments of perinatal neurodevelopment. The proposed book seeks to fill this gap by presenting a collection of chapters from leading experts in the field. It is intended to be comprehensive and will cover all aspects of neurodevelopmental programming in lab animals and in human subjects. The third section of the book will look at ways of translating insights we have garnered from animal studies to human and clinical studies. The primary audience for this work is basic researchers interested in the effects of perinatal imprinting on the development of the nervous system and associated diseases.

Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer Science & Business Media. This book was released on 2012-01-02 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Download or read book Maternal Obesity and Pregnancy written by Per Glud Ovesen and published by Springer Science & Business Media. This book was released on 2012-03-16 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic and worldwide increase is occurring in the prevalence of overweight and obesity in women of childbearing age. Obese women carry a significant excess risk of a variety of serious complications during pregnancy, and in addition, maternal obesity predisposes to obesity in the offspring. This book provides a timely update on the latest knowledge on maternal obesity and pregnancy. A very wide range of issues are covered, including macrosomia and associated shoulder dystocia; the risk of miscarriage, malformations, and complications of pregnancy; the impact of hyperglycemia; clinical management; consequences for anesthesia and ultrasound; impacts on breastfeeding, fertility, and childhood obesity; and pregnancy following gastric surgery. All of the authors are recognized experts in their fields, and the book has been designed to meet the practical needs of obstetricians, gynecologists, internists, and general practitioners.

Download or read book Vibrant and Healthy Kids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-12-27 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are the foundation of the United States, and supporting them is a key component of building a successful future. However, millions of children face health inequities that compromise their development, well-being, and long-term outcomes, despite substantial scientific evidence about how those adversities contribute to poor health. Advancements in neurobiological and socio-behavioral science show that critical biological systems develop in the prenatal through early childhood periods, and neurobiological development is extremely responsive to environmental influences during these stages. Consequently, social, economic, cultural, and environmental factors significantly affect a child's health ecosystem and ability to thrive throughout adulthood. Vibrant and Healthy Kids: Aligning Science, Practice, and Policy to Advance Health Equity builds upon and updates research from Communities in Action: Pathways to Health Equity (2017) and From Neurons to Neighborhoods: The Science of Early Childhood Development (2000). This report provides a brief overview of stressors that affect childhood development and health, a framework for applying current brain and development science to the real world, a roadmap for implementing tailored interventions, and recommendations about improving systems to better align with our understanding of the significant impact of health equity.

Download or read book Handbook of Prenatal and Perinatal Psychology written by Klaus Evertz and published by Springer Nature. This book was released on 2020-10-27 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The handbook synthesizes the comprehensive interdisciplinary research on the psychological and behavioral dimensions of life before, during, and immediately after birth. It examines how experiences during the prenatal period are associated with basic physiological and psychological imprints that last a lifetime and explores the ways in which brain networks reflect these experiences. Chapters offer findings on prenatal development, fetal programming, fetal stress, and epigenetics. In addition, chapters discuss psychotherapy for infants – before, during, and after birth – as well as prevention to promote positive health and well-being outcomes. Topics featured in this handbook include: Contemporary environmental stressors and adverse pregnancy outcomes The psychology of newborn intensive care. Art therapy and its use in treating prenatal trauma. The failures and successes of Cathartic Regression Therapy. Prenatal bonding and its positive effects on postnatal health and well-being. The role of family midwives and early prevention. The cultural meaning of prenatal psychology. The Handbook of Prenatal and Perinatal Psychology is an essential resource for researchers, clinicians and related professionals, as well as graduate students in a wide range of interrelated disciplines, including developmental psychology, pediatric and obstetrical medicine, neuroscience, infancy and early child development, obstetrics and gynecology, nursing, social work, and early childhood education.

Download or read book The Psychology of Prenatal Development written by Klaus Evertz and published by Taylor & Francis. This book was released on 2024-11-22 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book introduces the basics of prenatal psychology and works through the current scientific findings in the psychology and psychosomatics of pregnancy and birth. Through exploring bio-psycho-social relationships, as well as historical and cultural perspectives, this interdisciplinary approach easily breaks down specialist discussions into easy-to-understand concepts. Bridging the gap between foetal programming and psychological research and practice, this accessible book presents the history of the field and the basic concepts of prenatal development before exploring the behavioural dimensions of life before, during, and immediately after birth. Topics include sensory and emotional development in the womb, perception and brain development, the influence of environmental factors and prenatal imprinting and long-term effects. The author also delves into the concept of attachment and support and analyses body symptoms, sensations, feelings and inner images in dreams and imaginations, through the role of art creations and biographical narratives. As a whole, this book provides a therapeutic synopsis of the entire existence, which begins with conception. Explaining how experiences in the prenatal period influence basic psychological imprints across the lifespan, this book is an essential resource for students in a wide range of interrelated disciplines, including developmental psychology, paediatric medicine, neuroscience, infancy and early child development, nursing, social work and early childhood education. It may also be of interest to researchers, clinicians and related professionals.

Download or read book Parental Obesity Intergenerational Programming and Consequences written by Lucy R. Green and published by Springer. This book was released on 2016-11-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children’s future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges that need to be overcome in order to break the intergenerational cycle of obesity. This has profound implications for the way in which scientific, clinical and health policy activities are to be directed in order to combat the so-called epidemic of obesity, as well as diabetes, cancer and cardiovascular disease. The book will be of interest to students, clinicians, researchers and health policy makers who are either seeking an introduction to the area of Developmental Origins of Health and Disease or have a specific interest in the pathogenesis of obesity.

Download or read book Disease Control Priorities Third Edition Volume 2 written by Robert Black and published by World Bank Publications. This book was released on 2016-04-11 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.

Download or read book Diet Nutrition and Fetal Programming written by Rajkumar Rajendram and published by Humana Press. This book was released on 2017-10-13 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers the most comprehensive coverage on fetal programming. Chapters are written by authors of international and national standing, leaders in the field and trendsetters. The clinical relevance of the current research is emphasized in each chapter, which also contains key points, key words, and concise summaries for ease of learning. Fetal programming affects conditions in the immediate postnatal period, as well as in later life and adulthood. These conditions include cardiovascular disease, frank hypertension, stroke, dyslipidemia, coagulopathy, increased insulin resistance-metabolic syndrome, type-2 diabetes, leukemia, testicular cancer, prostate cancer, breast cancer, polycystic ovary syndrome, precocious puberty, impaired immune function, renal disease, lung disease, and osteoporosis. Neuropathologies, behavioral and mental deficiencies, schizophrenia, and depression have also been reported in adults who were exposed to nutritional inadequacies in utero. Diet, Nutrition and Fetal Programming provides an overview on the effects of fetal programming on disease, and comprehensive looks at maternal nutrition factors and fetal programming effects on brain and behavior, and physiology and disease. It also provides an in depth look at specific nutrient restrictions and supplements on physiology and disease, the effects of maternal disease on fetal programming, mechanisms of programming, and a special section on the international aspects and policies on fetal programming.

Download or read book The Placenta and Human Developmental Programming written by Graham J. Burton and published by Cambridge University Press. This book was released on 2010-12-16 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.

Download or read book Innovative Technologies and Signal Processing in Perinatal Medicine written by Danilo Pani and published by Springer Nature. This book was released on 2020-10-20 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pregnancy is a critical time for the health of the mother and the fetus, with important potential risks for both. Tools for antenatal diagnosis and pregnancy monitoring can support prevention and management of potential risks and complications. In particular, the perinatal period, spanning from the third trimester of pregnancy up to one month after birth, is the most critical for the baby. For this reason, in the last decades, biomedical engineering supported and fostered the scientific research towards the identification of new models, parameters, algorithms, and tools that can improve the quality of fetal monitoring, predict the outcomes and allow physicians to intervene in an appropriate manner to ensure a healthy future for the baby. This book follows the First International Summer School on Technologies and Signal Processing in Perinatal Medicine and reflects some of its most important master lectures. It represents a valuable guide for students and young researchers approaching this topic for the first time, as well as experienced researchers and practitioners looking for a clear representation of the themes and techniques presented by recognized experts in the field. Presents current and innovative technologies for fetal and neonatal monitoring Emphasis on both technology/signal processing and clinical aspects Offers a clear didactic approach to the subject matter

Download or read book Early life epigenetic programming of health and disease through DOHaD perspective written by Luis Antonio Justulin and published by Frontiers Media SA. This book was released on 2023-03-15 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Reducing the Odds written by National Research Council and published by National Academies Press. This book was released on 1999-02-13 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of HIV-positive women give birth every year. Further, because many pregnant women are not tested for HIV and therefore do not receive treatment, the number of children born with HIV is still unacceptably high. What can we do to eliminate this tragic and costly inheritance? In response to a congressional request, this book evaluates the extent to which state efforts have been effective in reducing the perinatal transmission of HIV. The committee recommends that testing HIV be a routine part of prenatal care, and that health care providers notify women that HIV testing is part of the usual array of prenatal tests and that they have an opportunity to refuse the HIV test. This approach could help both reduce the number of pediatric AIDS cases and improve treatment for mothers with AIDS. Reducing the Odds will be of special interest to federal, state, and local health policymakers, prenatal care providers, maternal and child health specialists, public health practitioners, and advocates for HIV/AIDS patients. January

Download or read book A Perinatal Strategy For Preventing Adult Disease The Role Of Long Chain Polyunsaturated Fatty Acids written by Undurti N. Das and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes that fetal growth retardation and low-grade systemic inflammation can be prevented by perinatal supplementation of long-chain polyunsaturated fatty acids (LCPUFAs). Evidence for this hypothesis is presented and discussed in detail, along with possible mechanisms by which these substances produce beneficial actions. Finally, it is suggested that provision of adequate amounts of LCPUFAs during the perinatal period prevents insulin resistance, obesity, type 2 diabetes mellitus, hypertension, CHD, and Alzheimer's disease in the adult. Means of testing the hypothesis are also presented. Thus, the book suggests a simple and novel method of preventing diseases that are increasing in incidence in both the developed and developing worlds.

Download or read book The Window of Opportunity written by David James Purslove Barker and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no longer any doubt that the inherited genetic constitution of the individual has a large influence on the entire life cycle, from human fetal development and pre- and postnatal growth to subsequent health status. However, growing evidence suggests that this predisposition is not rigid, but that early genetic imprinting, caused by exposure to a diverse spectrum of nutrients, macromolecules, microbial agents and other cellular or soluble components present in the external environment, is also of importance. According to this concept of the developmental origins of adult diseases, intrauterine and early life events play an important role in the etiology of human diseases: there seems to exist a critical 'window of opportunity' in the human infant before and during pregnancy, and up to 24 months of age. Altered exposure to different environmental agents during this critical period may determine the nature of responses in the perinatal period, and the expression of specific disease states in later life. The papers presented in this publication thus focus on the impact of perinatal growth, nutrition, environmental microflora, and host immune responses on the outcome of health and disease in later life.