Download or read book Pathophysiology and Management of Coagulation Disorders in Critical Care Medicine written by Evert de Jonge and published by . This book was released on 2000 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Life Threatening Coagulation Disorders in Critical Care Medicine written by Viola Hach-Wunderle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercoagulability and bleeding are problems physicians frequently encounter when treating intensive care patients. The coagulation mechanism is a tightly controlled system. Its balance is disturbed in conditions such as septicemia, trauma, shock, and others. The dis turbances may be local or disseminated and the therapeutic options available are limited and nonspecific: limited since in most cir cumstances they may not affect the underlying disease and are si milarly independent of the pathogenic mechanism; nonspecific since they cannot be specifically targeted to the problem of local or sys temic disturbance of coagulation. Furthermore, increased and de creased coagulability may be present at the same time. Activation of coagulation may lead to fibrin deposition and decreased hemostatic capacity, as seen in disseminated intravascular coagulation. New diagnostic approaches for acquired disorders of coagulation have been developed and form a new basis for therapeutic strategies. Despite this progress, many physicians are aware of the problem that, especially for intensive care patients, a treatment very often has to be selected before diagnostic procedures can be completed. We also know that for many diseases rare occurrence or the hetero genity of the patient population make it quite difficult to conduct clinical studies which prove that a therapeutic regimen is efficacious. Thus, much discussion about coagulation disorders in critically ill patients is still necessary. Even so, it is important to provide guidelines for handling these problems.

Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Download or read book Hemocoagulative Problems in the Critically Ill Patient written by Giorgio Berlot and published by Springer Science & Business Media. This book was released on 2012-04-05 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.

Download or read book Trauma Induced Coagulopathy written by Hunter B. Moore and published by Springer Nature. This book was released on 2020-10-12 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.

Download or read book Coagulation Endothelial Dysfunction An Issue of Critical Care Clinics written by Hernando Gomez and published by Elsevier Health Sciences. This book was released on 2020-03-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, guest edited by Drs. Hernando Gomez Danies and Joseph Carcillo, focuses on Coagulation/Endothelial Dysfunction. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Cell-cell communication breakdown and endothelial dysfunction; Role of the Tie2/Angiopoetin pathway in endothelial dysfunction; The Glycocalyx; Platelet activation and endothelial dysfunction; Role of antithrombin III and tissue factor pathway; Red blood cell dysfunction; Microvascular hemodynamics, autoregulation and mechanotransduction control of blood flow distribution; Nitric oxide and endothelial dysfunction; Microvascular dysfunction; Hemolytic Uremic Syndrome and atypical HUS; Thrombotic thrombocytopenic purpura, Heparin induced thrombocytopenia and Disseminated intravascular coagulation in the critically ill; Thrombocytopenia associated multiple organ failure (TAMOF); Meningococcemia; Immune consequences of endothelial dysfunction during sepsis; Therapeutic targets in thrombotic microangiopathies with a focus on endothelial disorders; and Coagulation disorders in HLH/Macrophage activation syndrome.

Download or read book Congenital Bleeding Disorders written by Akbar Dorgalaleh and published by Springer. This book was released on 2018-07-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.

Download or read book Coagulation Disorders written by Michael Laposata and published by Demos Medical Publishing. This book was released on 2010-09-17 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Doody's Core Title 2012 Each day pathologists are faced with ordering laboratory tests with which they are unfamiliar. An incorrectly ordered test or error in interpreting test results can lead to mistakes that compromise patient safety. Coagulation Disorders is designed to show clinical pathologists, lab managers, medical technologists, and residents how to avoid common errors in test selection and result interpretation in diagnostic coagulation. Utilizing a case-based approach, each chapter features a concise overview of a major diagnosis, with multiple illustrative cases, and then a list of recommended standards of care pertinent to the problem. Just as it is essential for the practitioner in the diagnosis of bleeding and thrombotic disorders to know the appropriate course of action to establish a diagnosis or to appropriately treat a patient, it is equally essential to also know what not to do. Avoiding the mistakes is a critical first step to optimizing patient outcome and maximizing patient safety. Features of Coagulation Disorders include: An emphasis on identifying established, evidence-based standards in coagulation testing Actual case illustrations of commonly seen errors as well as the result of those errors on patient outcome and laboratory management Examples of errors which compromise patient safety across all major areas of laboratory medicine Pocket-sized for portability About the Series A key issue for every laboratory and individual laboratory practitioner is the assessment of risk and a current working knowledge of the standards of care established for diagnostic testing via guidelines, major studies and trials. The Diagnostic Standards of Care series presents common errors associated with diagnoses in clinical pathology, using case examples to illustrate effective analysis based on current evidence and standards. In addition to being practical diagnostic guides, each volume demonstrates the use of quality assurance and the role of the pathologist in ensuring quality and patient safety."

Download or read book Disseminated Intravascular Coagulation DIC written by Balwinder Singh and published by Nova Biomedical Books. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disseminated Intravascular Coagulation is a devastating syndrome characterised by the systemic activation of widespread activation of the coagulation cascade and thrombosis, which may result in severe bleeding and may lead to organ failure. Recent studies have shown that the incidence of DIC is decreasing, especially in men. Despite the improvements in health care delivery, the morbidity and mortality due to DIC remains very high. Early diagnosis and accurate prognosis are important in improving the outcomes of patients with DIC. However, there is a lack of a gold standard diagnostic test to diagnose DIC and there is a scarcity of treatment or management strategies. Therefore, an understanding of the pathophysiology, ability to diagnose the DIC syndrome and treat it early, is the key. This book provides an important timely update on the clinical manifestations, important risk factors, and treatment strategies for DIC, and provides in-depth information on pathophysiological aspects and various diagnostic scores used to diagnose DIC. Furthermore, we focused on certain important factors related to DIC such as sepsis, chronic DIC in cancer patients, coagulopathy of liver disorders vs. DIC, and DIC in urological malignancies. In addition, this book provides evidence from an important study determining the predictors influencing the hospital mortality rates of critically ill patients with DIC. This book offers a wide scope of information for physicians in all fields, whether they are intensivists, primary care physicians or oncologists, this will be an important source for identifying the DIC syndrome early, and the appropriate steps to improve patient outcomes will be taken sooner.

Download or read book CURRENT Diagnosis and Treatment Critical Care Third Edition written by Frederic Bongard and published by McGraw Hill Professional. This book was released on 2008-07-13 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: All the management and diagnosis strategies you need in the critical care environment A Doody's Core Title for 2011! CURRENT Diagnosis & Treatment: Critical Care delivers authoritative and clinically focused guidance in a concise, find-it-now format. Following the trusted LANGE approach, it includes a review of the etiology, relevant pathophysiology, and clinical symptoms as a prelude to diagnosis and treatment. Coverage includes everything from renal failure and surgical infections to coronary heart disease. There is a strong emphasis on evidence-based medicine throughout. Features: Comprehensive overview of 39 key critical care topics, covering critical care basics, medical critical care, and the essentials of surgical critical care Valuable perspectives on the latest technologies, equipment, therapeutic strategies, and interventions Addresses common but difficult-to-diagnose critical care problems and delivers “approach to the patient” strategies NEW! Important treatment strategies for venous thromboembolism, acute respiratory distress syndrome, diabetic ketoacidosis, asthma, sepsis, and many more NEW! Current recommendations for deep vein thrombosis prophylaxis, transfusions, goal-directed therapy in sepsis, mechanical ventilation, use of pulmonary artery catheters, and glycemic control NEW! PMID numbers on all references for easy look-up

Download or read book Hemorrhagic Shock written by Jose L. Pascual and published by Nova Biomedical Books. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this first version of the book Hemorrhagic Shock: Recognition, Pathophysiology and Management, the entire spectrum of hemorrhage in various pathologic conditions is explored with a particular emphasis on bleeding from injury. World class experts have summarised their benchtop or clinical investigation of severe bleeding and the subsequent hosts response. Furthermore, contemporary content experts have been assembled to relate their own clinical expertise flanked by literature consensus in the subject. Navigation through the different chapters reveals succinct discussions about epidemiology, pathophysiology, bedside assessment and laboratory investigations. In addition, an important part of the content is practical approaches to the management and/or control of difficult hemorrhage sites including the diagnosis, management, adjunct, pharmaceutical and operative options available for the care of these patients. Additionally, separate chapters are presented for exploring areas related to bleeding in unique patients, including maternal-fetal medicine, prehospital and austere environment settings. Finally, the most novel and cutting edge materials, adjuncts and pharmacological agents are discussed as well as a concerted vision of what the future is likely going to bring to the care of these patients. The authorship reflects a multitude of backgrounds and disciplines, all focused on mitigating the impact of hemorrhage and hemorrhagic shock in its multiple facets. Trainees, advanced practice providers, fellows, attending surgeons, traumatologists, anesthesiologists, emergency physicians and intensivists will find valuable information derived from the vast experiences of the authors and their concise presentation of the most current literature in this dynamic field.

Download or read book Pediatric Bleeding Disorders written by Amy L. Dunn and published by Springer Nature. This book was released on 2020-03-28 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.

Download or read book Hemocoagulative Problems in the Critically Ill Patient written by Giorgio Berlot and published by Springer. This book was released on 2012-04-11 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.

Download or read book Coagulation Disorders in Obstetrics written by Henner Graeff and published by Saunders Limited.. This book was released on 1980 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Acute Pulmonary Embolism written by A. Geibel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.

Download or read book Venous Thromboembolism in Critical Care written by Kenneth E. Wood and published by Clinics: Internal Medicine. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historical Perspective of Venous Thromboembolism;Coagulation for the Intensivist;VTE Prophylaxis in the Critically Ill;Risk Stratification of Pulmonary Embolism; Treatment of Pulmonary Embolism: Anti Coagulation; Thrombolytic Therapy and Complications; Major Pulmonary Embolism;Catheter and Surgical Thromboembolectomy;Vena Caval Interruption;New Anti-Coagulants;Heparin Induced Thrombocytopenia

Download or read book Cardiothoracic Critical Care written by Natalia S. Ivascu and published by Oxford University Press, USA. This book was released on 2020 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Practicing critical care entails understanding human physiology, pharmacokinetics and molecular pathways in concert with adherence to evidence based literature. Some may say combining all of these entities into practice creates the "art" of critical care medicine. One strategy to gain proficiency in the practice of critical care medicine is to simulate what you would do in specific problem-based scenarios. That is the aim of this textbook aptly titled" "What Do I Do Now?" This text focuses on Cardiothoracic Critical Care and will cover guidelines for evidence-based practice, respiratory and metabolic physiology, common hemodynamic perturbations, ventricular failure and mechanical circulatory support devices. All clinicians who care for cardiothoracic patients who are critically ill can find pearls of practice wisdom complemented by literature citations within this text. So go ahead, place yourself at the foot of the bed and try to think through, "What Would I Do Now" when presented with each patient within these pages of your handheld cardiothoracic intensive care unit"--