Download or read book Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Tubal Gut Liver and Pancreaticobiliary System A Contemporary Update An Issue of Gastroenterology Clinics of North America E Book written by Robert D. Odze and published by Elsevier Health Sciences. This book was released on 2024-02-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Gastroenterology Clinics, guest editor Dr. Robert Odze brings his considerable expertise to the topic of Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Tubal Gut, Liver, and Pancreaticobiliary System: A Contemporary Update. Top experts review all the basic advances in the biology of neoplastic precursor lesions and its molecular and clinical implications to provide a better and more uniform understanding of mechanisms of cancer development in the gastrointestinal system and related organs. - Contains 10 relevant, practice-oriented topics including Barrett's esophagus and associated dysplasia; hepatic precancerous lesions and early hepatocellular carcinoma; pathology and clinical significance of inflammatory bowel disease-associated colorectal dysplastic lesions; sporadic colorectal polyps of the colon; pathology of gastrointestinal polyposis disorders; and more. - Provides in-depth clinical reviews on neoplastic precursor lesions of the tubal gut, liver, and pancreaticobiliary system, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Tubal Gut Liver and Pancreaticobiliary System A Contemporary Update an Issue of Gastroenterology Clinics of North America written by Robert D. Odze and published by Elsevier. This book was released on 2024-03-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Gastroenterology Clinics, guest editor Dr. Robert Odze brings his considerable expertise to the topic of Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Tubal Gut, Liver, and Pancreaticobiliary System: A Contemporary Update. Top experts review all the basic advances in the biology of neoplastic precursor lesions and its molecular and clinical implications to provide a better and more uniform understanding of mechanisms of cancer development in the gastrointestinal system and related organs. Contains 10 relevant, practice-oriented topics including Barrett's esophagus and associated dysplasia; hepatic precancerous lesions and early hepatocellular carcinoma; pathology and clinical significance of inflammatory bowel disease-associated colorectal dysplastic lesions; sporadic colorectal polyps of the colon; pathology of gastrointestinal polyposis disorders; and more. Provides in-depth clinical reviews on neoplastic precursor lesions of the tubal gut, liver, and pancreaticobiliary system, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Pathology and Clinical Relevance of Neoplastic Precursor Lesions of the Gastrointestinal Tract Liver and Pancreaticobiliary System written by Robert D. Odze and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to recent advances in endoscopy and radiology, there is increased recognition of the prevalence and biological characteristics of neoplastic precursor lesions in the GI tract, liver, biliary tract, and pancreas. As a result, there have been major recent developments in the pathologic classification, diagnosis, molecular pathogenesis, natural history and treatment of these lesions. In addition, there are controversial issues with regard to the value of endoscopic screening and surveillance. A close clinician-pathologist interaction is essential in the management of preneoplastic lesions. In this issue the pathology, biological properties, pathogenesis, natural history, and current treatment recommendations of the major preneoplastic and dysplastic precursor lesions of the GI tract, liver, biliary tract and pancreas are reviewed in detail. Wherever possible, accent is given to controversial diagnostic and management-related issues. Each subject matter is written by experts in the field, all of whom have had research experience in their respective areas.

Download or read book Advances in Intestinal Transplantation Part I An Issue of Gastroenterology Clinics of North America E Book written by Alan L Buchman and published by Elsevier Health Sciences. This book was released on 2024-05-10 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Intestinal Transplantation, Part I, An Issue of Gastroenterology Clinics of North America, E-Book

Download or read book Advances in Intestinal Transplantation Part II An Issue of Gastroenterology Clinics of North America E Book written by Alan L Buchman and published by Elsevier Health Sciences. This book was released on 2024-07-31 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Gastroenterology Clinics, guest editor Dr. Alan L. Buchman brings his considerable expertise to the topic of Advances in Intestinal Transplantation, Part II. In this second of two issues devoted to the comprehensive coverage of this topic, top experts discuss the complexities of intestinal failure (IF) and provide a better understanding of medical and surgical management. Coverage also includes assessment of when patients should be referred to select centers of expertise where both medical and surgical (nontransplant and transplant) modalities are available. - Contains 12 relevant, practice-oriented topics including innate and cellular immune responses in intestinal transplantation: new discoveries: altering the microbiome and implications for host metabolomics; vaccines and vaccine response: other maintenance care in the small bowel transplant patient; living donor intestinal transplantation; the stem cell niche in short bowel syndrome; and more. - Provides in-depth clinical reviews on advances in intestinal transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Gastrointestinal and Liver Pathology E Book written by Christine A. Iacobuzio-Donahue and published by Elsevier Health Sciences. This book was released on 2011-06-06 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal and Liver Pathology, a title in the Foundations in Diagnostic Pathology series, provides all the most essential information on the pathological entities encountered in practice in an easy-to-use format. Drs. Christine A. Iacobuzio-Donahue and Elizabeth Montgomery examine the full scope of neoplastic and non-neoplastic disorders of the gastrointestinal tract--, including disorders of the tubular gastrointestinal tract, pancreatobiliary tree, and liver—from clinical features and ancillary studies to differential diagnoses and prognostic and therapeutic considerations. The consistent, practical format with a wealth of illustrations, boxes, and tables make this title ideal for quick reference for both novices and experienced pathologists. Get the full range of coverage on neoplastic and non-neoplastic gastrointestinal/liver conditions in a consistent, user-friendly format. Catch all the nuances of how pathological entities present through over 850 full-color illustrations. Reference key information quickly and easily thanks to at-a-glance boxes and tables throughout the text. Stay current with the latest in molecular diagnostic techniques through a new chapter on this increasingly important topic. Find information on lymphoid neoplasms of the GI tract more easily with coverage consolidated into a new, focused chapter. Easily identify newly described entities highlighted in updated images and references. Enhance your visual understanding from 100 new clinical and photomicroscopic images. Gain increased at-a-glance reference thanks to more fact sheets and pathologic features boxes.

Download or read book Pancreatobiliary Pathology An Issue of Surgical Pathology Clinics E Book written by Aatur D. Singhi and published by Elsevier Health Sciences. This book was released on 2022-09-02 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Surgical Pathology Clinics, guest editor Dr. Aatur D. Singhi brings his considerable expertise to the topic of Pancreatobiliary Neoplastic Pathology. Top experts in the field discuss precursor and malignant neoplasms (with mimics) such as molecular discoveries (e.g., IOPNs), neoadjuvant treatment histopathology (e.g., grading), immunohistochemical biomarkers (e.g., prognostic markers for neuroendocrine tumors), and more. Contains 13 relevant, practice-oriented topics including the diagnostic challenge of evaluating small biopsies from the pancreatobiliary system; integrating molecular analysis to the pathologic evaluation of pancreatic cysts; the cytomorphologic and molecular assessment of bile duct brushing specimens; advances in the surgical approach to pancreatobiliary neoplasms; and more. Provides in-depth clinical reviews on pancreatobiliary neoplastic pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Neoplastic Gastrointestinal Pathology An Illustrated Guide written by Laura W. Lamps, MD and published by Springer Publishing Company. This book was released on 2015-07-15 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concisely written, abundantly illustrated guide to a wide range of topics in gastrointestinal neoplasia facilitates the evaluation and accurate diagnosis of gastrointestinal neoplasms, both straightforward and challenging. This approachable guide covers the entire tubular GI tract and features more than 600 high quality images. Written and arranged with the busy practicing pathologist in mind, this practical guide includes, for each entity, definitions and terminology, gross and morphologic features, differential diagnoses, useful ancillary tests, staging and grading parameters, and clinical considerations. Beautiful color figures throughout the volume highlight essential histologic features as well as differential diagnoses and potential diagnostic pitfalls. The book is organized into six introductory chapters focused on approaches to neoplasia, followed by 6 organ-specific chapters covering each segment of the GI tract. The final two chapters offer an in-depth discussion of immunohistochemistry and molecular pathology of gastrointestinal neoplasia. This book is a vital reference for practicing pathologists, and with its clear, concise presentation it is also an excellent resource for pathologists in training. Key Features: Provides clear, concise coverage of neoplastic disease across the entire tubular gastrointestinal tract Offers over 600 high-quality images highlighting key differential points and potentially misleading variants Comprehensive tables cover diagnostic features, tumor types, and other crucial data for pathologists About the Authors: Laura W. Lamps, MD, is Professor and Vice-Chair for Academic Affairs, Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR Andrew M Bellizzi, MD, is Clinical Associate Professor, Department of Pathology, University of Iowa Hospitals and Clinics, University of Iowa Carver College of Medicine; Co-Director of Immunopathology Laboratory and Co-Director of GI Pathology, Holden Comprehensive Cancer Center, Iowa City, IA

Download or read book Gastrointestinal and Liver Pathology E Book written by Amitabh Srivastava and published by Elsevier Health Sciences. This book was released on 2022-10-29 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what's new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.Key features of this practical text include: - A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations. - A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses. - Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis. - Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout. What's NEW in this edition: - Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine. - New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities. - The latest TNM staging and WHO classification systems. - New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field.

Download or read book Gastrointestinal Neoplasia An Issue of Gastroenterology Clinics of North America written by Paul J. Limburg and published by Elsevier Health Sciences. This book was released on 2016-08-24 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) cancers account for nearly 150,000 deaths each year, in the United States alone. Encouragingly, environmental risk factors, premalignant conditions, and high-risk familial kindreds are well described for many GI cancers. In this comprehensive volume on GI Neoplasia, all luminal cancers will be discussed, along with pancreas cancer, gastrointestinal stromal tumors (GISTs), carcinoid tumors, and neuroendocrine tumors. Hepatobiliary cancers are not addressed, as these tumors could form the basis of a separate volume. Articles are organized to address several key topics for each cancer type, such as: public health burden, molecular pathways, risk and protective factors, early detection, clinical evaluation, management, and survivorship.

Download or read book Odze and Goldblum Surgical Pathology of the GI Tract Liver Biliary Tract and Pancreas E Book written by Robert D. Odze and published by Elsevier Health Sciences. This book was released on 2014-09-11 with total page 1893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated edition of Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas is designed to act as a one-stop medical reference book for the entire gastrointestinal system, providing exhaustive coverage and equipping you with all of the necessary tools to make a comprehensive diagnostic workup. You'll access thousands of high-quality illustrations and eight brand-new chapters, so you can recognize and diagnose any pathological slide you encounter. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make a comprehensive diagnostic workup with data from ancillary techniques and molecular findings whenever appropriate. Effectively grasp complex topics and streamline decision-making by using extensive tables, graphs, and flowcharts. Avoid diagnostic errors thanks to practical advice on pitfalls in differential diagnosis. Navigate the book quickly with a "road map" featured at the beginning of each chapter. Provide the clinician with the most accurate and up-to-date diagnostic and prognostic indicators, including key molecular aspects of tumor pathology, with access to the latest classification and staging systems available. Evaluate diagnostically challenging cases using diagnostic algorithms. Stay abreast of the latest advances with eight new chapters: Autoimmune Disorders of the GI Tract; Drug Induced Disorders of the GI Tract; Molecular Diagnostics of Tubal Gut Neoplasms; Molecular Diagnostics of the Gallbladder, Extrahepatic Biliary Tree, and Pancreatic Tumors; Tumors of the Ampulla; Molecular Diagnostics of Hepatocellular Neoplasms; Approach to the Liver Biopsy, and Approach to Gastrointestinal Tract Biopsies. Remain at the forefront of your field with coverage of new molecular and genetic markers in GI neoplasms; updated knowledge on liver and biliary tree pathology; and expanded information on tumors of the ampulla. Recognize and diagnose any tissue sample under the microscope with help from over 3000 high-quality color illustrations.

Download or read book Surgical Pathology of the GI Tract Liver Biliary Tract and Pancreas written by Robert D. Odze and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 1387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This one-of-a-kind reference provides a comprehensive and practical guide to help you interpret endoscopic biopsies and resection specimens of all organs related to the digestive system. Plus, thanks to Expert Consult, you'll be able to access the entire contents of this title online and download all images, from anywhere there's an internet connection. The more than 2250 high quality illustrations, 30% more than in the first edition, help you recognize and diagnose any tissue sample under the microscope. Five new chapters, additional expert authors, expanded tables, and coverage of the current clinical approach to management and treatment options, particularly screening and surveillance recommendations for preneoplastic disorders, round out this unique reference. Acts as a one-stop resource for the entire gastrointestinal system, liver, biliary tract, and pancreas. Incorporates over 2250 high quality color illustrations so you can recognize and diagnose any tissue sample under the microscope. Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. Simplifies complex topics and streamlines decision-making using extensive tables, graphs, and flowcharts. Helps you avoid diagnostic errors thanks to practical advice on pitfalls in differential diagnosis. Uses a new "road map" at the beginning of each chapter, as well as a new, more clinical focus to help you navigate through the book more quickly. Reflects the latest classification and staging systems available so you can provide the clinician with the most accurate and up-to-date diagnostic and prognostic indicators, including key molecular aspects of tumor pathology. Includes access to the entire contents online, from anywhere there's an internet connection. Adds five new chapters including "Screening and Surveillance of the GI Tract", "Congenital and Developmental Disorders of the GI Tract", "Pediatric Enteropathies of the GI Tract", "Vascular Disorders of the GI Tract", and "Fatty Liver Disease". Expands appropriate chapters with new coverage of the normal histology of the GI tract, liver, biliary tract and pancreas. Uses expanded tables to outline specific differential diagnostic points helpful for surgical pathologists. Discusses the key molecular aspects of tumor progression and risk assessment in all chapters that cover neoplastic disorders. Helps you evaluate diagnostically challenging cases using diagnostic algorithms. Increases the number of high quality photographs by at least 30% to include even more normal and abnormal tissue samples. Updates all chapters to include the latest references, concepts, data, and controversies. Incorporates expanded coverage of the pancreas and liver, eliminating the need for a separate text. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Download or read book Pancreatobiliary Pathology an Issue of Surgical Pathology Clinics 15 written by Aatur D. Singhi and published by Elsevier. This book was released on 2022-06-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Surgical Pathology Clinics, guest editor Dr. Aatur D. Singhi brings his considerable expertise to the topic of Pancreatobiliary Neoplastic Pathology. Top experts in the field discuss precursor and malignant neoplasms (with mimics) such as molecular discoveries (e.g., IOPNs), neoadjuvant treatment histopathology (e.g., grading), immunohistochemical biomarkers (e.g., prognostic markers for neuroendocrine tumors), and more. Contains 13 relevant, practice-oriented topics including the diagnostic challenge of evaluating small biopsies from the pancreatobiliary system; integrating molecular analysis to the pathologic evaluation of pancreatic cysts; the cytomorphologic and molecular assessment of bile duct brushing specimens; advances in the surgical approach to pancreatobiliary neoplasms; and more. Provides in-depth clinical reviews on pancreatobiliary neoplastic pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Modern Management of Benign and Malignant Pancreatic Disease An Issue of Gastroenterology Clinics written by Jacques Van Dam and published by Elsevier Health Sciences. This book was released on 2012-03-28 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Van Dam is an internationally recognized leader in gastroenterology and has been a leader in advances in intervedntional endoscopy. He brings this expertise to the topic of management of benign and malignant pancreatic disease and has selected top experts in the field to provide state-of-the-art clinical information to gastroenterologists. The modern management treatise of each article addresses current diagnostics as well as medical management. Seven articles are devoted to pancreatic cancer and span medical management, surgial mangament, radiologic imaging, endoscopic diagnosis, palliation, and screening. Other important topics addressed are pancreatic transplantation, pancreatic cystic neoplasms, acute and chronic pancreatitis, and autoimmune pancreatitis.

Download or read book Gastrointestinal Pathology Classification Diagnosis Emerging Entities An Issue of Surgical Pathology Clinics E Book written by Jason L. Hornick and published by Elsevier Health Sciences. This book was released on 2013-09-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Overall, this book is an excellent update on many important entities..." Reviewed by: Kay Lawson, on behalf of ACP News; Date: Summer 2014. The gastrointestinal tract may be affected by a diverse spectrum of inflammatory and neoplastic disorders, many of which pose problems for practicing surgical pathologists on a daily basis. Pathologists' understanding of these diseases continues to evolve rapidly. The topics in this issue of Surgical Pathology Clinics address a wide range of neoplasms and present ancillary techniques that play an increasingly important role in diagnostic pathology and include prognostic and predictive markers that have become a routine part of gastrointestinal pathology practice. These expert reviews provide surgical pathologists with critical practical updates on many of these challenging areas, with an emphasis on differential diagnosis and diagnostic pitfalls. Some topics include: Lymphomas of the gastrointestinal tract; Mesenchymal tumors of the gastrointestinal tract other than GIST; Barrett's esophagus: evolving concepts in diagnosis and neoplastic progression; Immunohistochemistry in neoplastic gastrointestinal pathology; HER2 testing in adenocarcinomas of the upper gastrointestinal tract; Pediatric inflammatory gastrointestinal pathology; IgG4-related disorders of the gastrointestinal tract. The reader will be interested in cross referencing the first volume on GI pathology presented in this series; its popularity with surgical pathologists has led to this second volume, which covers different topics in GI pathology. Jason Hornick of Brigham and Women's provides his expertise to lead this issue.

Download or read book Morson and Dawson s Gastrointestinal Pathology written by Adrian C. Bateman and published by John Wiley & Sons. This book was released on 2024-10-21 with total page 1140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gold standard in gastrointestinal pathology textbooks returns More than 34 million Americans suffer from pathologies of the digestive system, with over 20 million of these disorders chronic. Treatment of these patients is a complex multidisciplinary area of clinical medicine, drawing upon expertise not only from specialist gastroenterologists but also pathologists, immunologists, endoscopists, and more. Morson & Dawson’s Gastrointestinal Pathology has long set the standard for pathology textbooks, with its distinctive balance of clinical gastroenterology and pathology. Now fully updated to reflect the latest research in this vital field of medicine, it promises to bring this subject to a new generation of clinicians and pathologists worldwide. Readers of the sixth edition of Morson and Dawson’s Gastrointestinal Pathology will also find: Contemporary recommendations and guidelines for getting the most out of every pathology specimen and producing the best possible report for managing the patient Discussions of the evolving applications of immunohistochemistry and in situ hybridisation A completely new chapter on lymphoid and other tumours of the large intestine Morson & Dawson’s Gastrointestinal Pathology is ideal for gastrointestinal pathologists, general pathologists, gastroenterologists, and any clinicians who work with or in gastrointestinal practice.

Download or read book Diagnostic Pathology Gastrointestinal written by Joel K. Greenson and published by Elsevier. This book was released on 2024-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of gastrointestinal pathology to help pathologists differentiate between closely related digestive tract disorders, this volume incorporates the most up-to-date scientific and technical knowledge, providing a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Gastrointestinal is a visually stunning, one-stop resource for every practicing pathologist, fellow, resident, or student as an ideal day-to-day reference or as a reliable training resource, and is useful to even the most experienced pathologist for current details on the diagnosis and characterization of neoplastic and nonneoplastic diseases of the digestive tract. Covers all areas of gastrointestinal pathology-from esoteric topics like microsporidia to common issues like serrated colorectal polyps Includes important new material on recently discovered genetic alterations in GI cancers, targeted gene therapies, and the changed approach to GI endocrine neoplasms, as well as numerous new chapters on other timely issues, such as COVID-19's effects on the GI system, drug-induced GI diseases, and more Contains significantly updated information throughout, including new content, images, and references that reflect the most current diagnoses, provide ease for daily case sign-out, and contain details related to the latest WHO Classification of Tumours: Digestive System Tumours Features more than 2,600 print and online-only images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images to help practicing and in-training pathologists reach a confident diagnosis Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date . 10-15 new chapters plus image, text, and Reference updates across the book's 200 chapters are in place for the 4th ed. of DP: Gastrointestinal. New chapters are added, and existing contents are updated, to address the newest WHO Classification of Digestive System Tumors. The updated Classification includes a change to how appendiceal neoplasms are classified. Additional new content covers the changed overall approach to gastrointestinal endocrine neoplasms and how to differentiate Grade 3 endocrine tumors from high grade neuroendocrine carcinomas. New 4th ed chapters also include details on targeted gene therapies and important genes now identified which involve primary cancers of the GI tract.