Download or read book Design and Processing of Particulate Products written by Jim Litster and published by Cambridge University Press. This book was released on 2016-10-20 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique text providing comprehensive coverage of fundamental particle science, processing and technology. Including quantitative tools, real-world case studies and end-of-chapter problems, it is ideal for students in engineering and applied sciences, as well as for practitioners in a range of industries manufacturing particulate products.

Download or read book Therapeutic Proteins written by C. Mark Smales and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets will escalate at an even greater rate than that observed in recent years. However, identification of a potential target is only part of the process in developing these new next generation protein-based “drugs” that are increasingly being used to treat human disease. Once a potential protein drug has been identified, the next rate-limiting step on the road to development is the production of sufficient authentic material for testing, charact- ization, clinical trials, and so on. If a protein drug does actually make it through this lengthy and costly process, methodology that allows the production of the protein on a scale large enough to meet demand must be implemented. Furthermore, large-scale production must not compromise the authenticity of the final product. It is also nec- sary to have robust methods for the purification, characterization, viral inactivation and continued testing of the authenticity of the final protein product and to be able to formulate it in a manner that retains both its biological activity and lends itself to easy administration. Therapeutic Proteins: Methods and Protocols covers all aspects of protein drug production downstream of the discovery stage. This volume contains contributions from leaders in the field of therapeutic protein expression, purification, characterization, f- mulation, and viral inactivation.

Download or read book Supercritical Fluid Technology for Drug Product Development written by Peter York and published by CRC Press. This book was released on 2004-03-23 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical prod

Download or read book Design and Processing of Particulate Products written by Jim Litster and published by Cambridge University Press. This book was released on 2016-10-20 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: With this unique and comprehensive text, readers will gain the quantitative tools needed to engineer the particulate processes and products that are ubiquitous in modern life. Covering a series of particle and particulate delivery form design processes, with emphasis on design and operation to control particle attributes, and supported by many worked examples, it is essential reading for students and practitioners. Topics covered include a range of particle design processes such as crystallization and precipitation, granulation, grinding, aerosol processes and spray drying, as well as forms of delivery such as granules, tablets, dry powders, and aerosols. Readers will learn from real-world examples how the primary particle properties and the structure and properties of the delivery form can lead to high performance products, ranging from pharmaceuticals, consumer goods and foods, to specialty chemicals, paints, agricultural chemicals and minerals.

Download or read book Developments in Surface Contamination and Cleaning Applications of Cleaning Techniques written by Rajiv Kohli and published by Elsevier. This book was released on 2018-11-27 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in Surface Contamination and Cleaning: Applications of Cleaning Techniques, Volume Eleven, part of the Developments in Surface Contamination and Cleaning series, provides a guide to recent advances in the application of cleaning techniques for the removal of surface contamination in various industries, such as aerospace, automotive, biomedical, defense, energy, manufacturing, microelectronics, optics and xerography. The material in this new edition compiles cleaning applications into one easy reference that has been fully updated to incorporate new applications and techniques. Taken as a whole, the series forms a unique reference for professionals and academics working in the area of surface contamination and cleaning. - Presents the latest reviewed technical information on precision cleaning applications as written by established experts in the field - Provides a single source on the applications of innovative precision cleaning techniques for a wide variety of industries - Serves as a guide to the selection of precision cleaning techniques for specific applications

Download or read book Phase Equilibrium Engineering written by Esteban Alberto Brignole and published by Newnes. This book was released on 2013-04-02 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, the teaching of phase equilibria emphasizes the relationships between the thermodynamic variables of each phase in equilibrium rather than its engineering applications. This book changes the focus from the use of thermodynamics relationships to compute phase equilibria to the design and control of the phase conditions that a process needs. Phase Equilibrium Engineering presents a systematic study and application of phase equilibrium tools to the development of chemical processes. The thermodynamic modeling of mixtures for process development, synthesis, simulation, design and optimization is analyzed. The relation between the mixture molecular properties, the selection of the thermodynamic model and the process technology that could be applied are discussed. A classification of mixtures, separation process, thermodynamic models and technologies is presented to guide the engineer in the world of separation processes. The phase condition required for a given reacting system is studied at subcritical and supercritical conditions. The four cardinal points of phase equilibrium engineering are: the chemical plant or process, the laboratory, the modeling of phase equilibria and the simulator. The harmonization of all these components to obtain a better design or operation is the ultimate goal of phase equilibrium engineering. - Methodologies are discussed using relevant industrial examples - The molecular nature and composition of the process mixture is given a key role in process decisions - Phase equilibrium diagrams are used as a drawing board for process implementation

Download or read book Current Trends of Supercritical Fluid Technology in Pharmaceutical Nutraceutical and Food Processing Industries written by Ana Rita C. Duarte and published by Bentham Science Publishers. This book was released on 2010-07-13 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluid technology can be seen as a green and environmentally friendly alternative to conventional. Current information on these topics is spread through different publications in different peer-reviewed journals. The editors were therefore of

Download or read book The Metrics of Material and Metal Ecology written by M.A. Reuter and published by Elsevier. This book was released on 2005-11-02 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a must for individuals and companies that have an interest in developing sustainable technology and systems in the complex 'Web of Metals' on a first principles, technological and economic basis, with a focus to the minerals, metals and product manufacturing industries. In this inter-, intra- and trans-disciplinary book the material/metal cycle will be central, addressing technology as the basis for achieving sustainability within the system of primary mineral and metal producing, and the consumer product material cycles, linked to nature's cycles. The following major topics (not exclusive) are discussed in a detail, which will satisfy company CEO's and students of environment, engineering, economics, and law alike: (i) industrial ecology, (ii) system engineering concepts, (iii) development of future breakthrough technology as well optimization of present technology, (iv) process fundamentals (e.g. thermodynamics, separation physics, transport processes etc.), (v) product manufacture and design (for recycling), (vi) environmental legislation and (vii) technology as a basis for achieving sustainability within our present society.The book discusses contentious issues such as the limits of recycling determined by physics, chemistry, economics and process technology, therefore providing the reader with a fundamental basis to understand and critically discuss the validity of environmental legislation. Furthermore, the 'Web of Metals' (i.e. the dynamic interconnection of metal and material cycles and product systems) will reveal that, if the application of environmental evaluation techniques such as material flow analysis, life cycle assessment etc. are not carried out on a sufficient theoretical basis, technological and economic understanding, analyses could lead to erroneous and in the end environmentally harmful conclusions.The book is illustrated with many industrial examples embracing car and electronic consumer goods manufacturing and recycling, and the production and recycling of all major metals (e.g. steel, aluminium, copper, zinc, lead, magnesium, PGM's and PM's) and to an extent plastics. A complete section of the book is devoted to the recycling of light metals. Numerous colour figures and photos, plant and reactor data as well as software and computer models (running under Matlab's Simulink® and AMPL® as well as tools based on neural net technology (CSenseTM) are provided to give the reader the opportunity to investigate the various topics addressed in this book at various levels of depth and theoretical sophistication, providing a wealth of information, share-data and industrial know-how.Finally, the book philosophically discusses how to harmonize the resource, life and technological cycles depicted by the figure on the cover to make a contribution to the sustainable use of resources and products.* Material and Metal Ecology and the various modelling aspects to quantify this * System modelling of recycling systems with applications in the automotive and consumergoods sector* Metallurgical metal recycling with applications in aluminium, supplemented with various modelling examples from thermodynamics, exergy, neural nets to CFD

Download or read book Phase Equilibrium Engineering written by Esteban Brignole and published by Elsevier Inc. Chapters. This book was released on 2013-04-02 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on phase equilibrium engineering (PEE) aims to fill the gap between the books on reactors and separation process design and the textbooks on chemical engineering thermodynamics. The goal is to change the focus from the use of thermodynamic relationships to compute phase equilibria to the design and control of the phase conditions that a process needs. In this way, phase equilibrium thermodynamics is put to work. The main goal of PEE is the design of the system conditions to achieve the desired phase equilibrium scenario that the process at hand requires. In this chapter, the philosophy of phase equilibrium thermodynamic modeling is discussed in the context of process development and chemical plant operation. Typical phase scenarios that are encountered in separation, materials, and chemical process are presented as well as the problem of phase design and the PEE tools.

Download or read book Image and Signal Processing written by Abderrahim El Moataz and published by Springer Nature. This book was released on 2020-07-08 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the refereed proceedings of the 9th International Conference on Image and Signal Processing, ICISP 2020, which was due to be held in Marrakesh, Morocco, in June 2020. The conference was cancelled due to the COVID-19 pandemic. The 40 revised full papers were carefully reviewed and selected from 84 submissions. The contributions presented in this volume were organized in the following topical sections: digital cultural heritage & color and spectral imaging; data and image processing for precision agriculture; machine learning application and innovation; biomedical imaging; deep learning and applications; pattern recognition; segmentation and retrieval; mathematical imaging & signal processing.

Download or read book Industrial Scale Natural Products Extraction written by Hans-Jörg Bart and published by John Wiley & Sons. This book was released on 2011-08-08 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the latest technologies in process engineering, this handbook and ready reference features high pressure processing, alternative solvents and processes, extraction technologies and biotransformations -- describing greener, more efficient and sustainable techniques. The result is an expert account of engineering details from lab-scale experiments to large-scale industrial design. The major focus is on the engineering aspects of extraction with organic and supercritical solvents, ionic liquids or surfactant solutions, and is supplemented by aspects of both up- and downstream processing, biotransformation, as well as a survey of typical products in food, pharmaceutical and cosmetic applications. This is rounded off by market developments, economic considerations and regulations requirements in the field Authored by experts from leading industrial and academic institutions, this is essential reading for the hands-on scientist and office manager alike.

Download or read book Handbook of Food Process Design written by Jasim Ahmed and published by John Wiley & Sons. This book was released on 2012-02-27 with total page 1543 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 21st Century, processing food is no longer a simple or straightforward matter. Ongoing advances in manufacturing have placed new demands on the design and methodology of food processes. A highly interdisciplinary science, food process design draws upon the principles of chemical and mechanical engineering, microbiology, chemistry, nutrition and economics, and is of central importance to the food industry. Process design is the core of food engineering, and is concerned at its root with taking new concepts in food design and developing them through production and eventual consumption. Handbook of Food Process Design is a major new 2-volume work aimed at food engineers and the wider food industry. Comprising 46 original chapters written by a host of leading international food scientists, engineers, academics and systems specialists, the book has been developed to be the most comprehensive guide to food process design ever published. Starting from first principles, the book provides a complete account of food process designs, including heating and cooling, pasteurization, sterilization, refrigeration, drying, crystallization, extrusion, and separation. Mechanical operations including mixing, agitation, size reduction, extraction and leaching processes are fully documented. Novel process designs such as irradiation, high-pressure processing, ultrasound, ohmic heating and pulsed UV-light are also presented. Food packaging processes are considered, and chapters on food quality, safety and commercial imperatives portray the role process design in the broader context of food production and consumption.

Download or read book Transport Phenomena In Particulate Systems written by José Teixeira Freire and published by Bentham Science Publishers. This book was released on 2012-03-31 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book presents recent advances in research in the field of particulate systems. A comprehensive background on operations involving particulate materials with a didactic approach is illustrated. Fundamentals and applications in a variety of multi-phase flow reactors are explained with a clear focus on the analysis of transport phenomena, experimental techniques and modeling. The volume spans 10 chapters covering different aspects of transport phenomena including fixed and fluidized systems, spouted beds, electrochemical and wastewater treatment reactors. This e-book will be valuable for students, engineers and researchers aiming to keep updated on the latest developments on particulate systems.

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2002 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Spherical Crystallization as a New Platform for Particle Design Engineering written by Yoshiaki Kawashima and published by Springer. This book was released on 2019-05-21 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the principles and applications of the spherical crystallization technique, from the standpoint of its inventor. After an introduction on the history of particle design engineering and nanotechnology, the concept of spherical crystallization itself is clearly explained. Attention then turns to the application of spherical crystallization in pharmaceutical processes. It is explained how the technique can provide physicochemical properties suitable for direct tableting of active pharmaceutical ingredients and how it has enabled the development of a novel particulate design platform from single to complex system. Subsequent chapters describe the roles of polymeric spherical crystallization in the preparation of novel microspheres, microballoons for drug delivery systems (DDS) and the development of biocompatible and biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanospheres. The various applications of PLGA nanospheres composite within oral-, pulmonary-, transdermal DDS and cosmetics are fully discussed. Finally, future perspectives are presented on use of the technology in the design and industrial-scale manufacture of new drug delivery systems, highlighting how a continuous pharmaceutical process that meets US Food and Drug Administration quality requirements should soon be introduced.

Download or read book Product Process and Plant Design Using Subcritical and Supercritical Fluids for Industrial Application written by Željko Knez and published by Springer Nature. This book was released on 2023-07-03 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes cutting edge technology using supercritical fluids for the production of foodstuffs, medicals, and polymers. It illustrates the importance and use of basic data for design and operation at industrial scale units. The book's authors have several decades of experience of applied research on how to develop large scale industrial units. It provides readers complete insight in design and operation of industrial high pressure process plants. The book is written so it may be understood for people (with?) little or no background on high pressure process technology. It will provide information on how some foodstuffs, medicals, polymers are produced using high pressure technologies. The book demonstrates the importance of fundamental data, how to measure them and how to apply them to design industrial plants. At the same time, it also serves as a textbook for students.

Download or read book Handbook of Aseptic Processing and Packaging written by Jairus R. D. David and published by CRC Press. This book was released on 2022-09-07 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nine years have passed since the second edition of the Handbook of Aseptic Processing and Packaging was published. Significant changes have taken place in several aseptic processing and packaging areas. These include aseptic filling of plant-based beverages for non-refrigerated shelf-stable formats for longer shelf life and sustainable packaging along with cost of environmental benefits to leverage savings on energy and carbon footprint. In addition, insight into safe processing of particulates using two- and three-dimensional thermal processing followed by prompt cooling is provided. In the third edition, the editors have compiled contemporary topics with information synthesized from internationally recognized authorities in their fields. In addition to updated information, 12 new chapters have been added in this latest release with content on Design of the aseptic processing system and thermal processing Thermal process equipment and technology for heating and cooling Flow and residence time distribution (RTD) for homogeneous and heterogeneous fluids Thermal process and optimization of aseptic processing containing solid particulates Aseptic filling and packaging equipment for retail products and food service Design of facility, infrastructure, and utilities Cleaning and sanitization for aseptic processing and packaging operations Microbiology of aseptically processed and packaged products Risk-based analyses and methodologies Establishment of "validated state" for aseptic processing and packaging systems Quality and food safety management systems for aseptic and extended shelf life (ESL) manufacturing Computational and numerical models and simulations for aseptic processing Also, there are seven new appendices on original patents, examples of typical thermal process calculations, and particulate studies—single particle and multiple-type particles, and Food and Drug Administration (FDA) filing The three editors and 22 contributors to this volume have more than 250 years of combined experience encompassing manufacturing, innovation in processing and packaging, R&D, quality assurance, and compliance. Their insight provides a comprehensive update on this rapidly developing leading-edge technology for the food processing industry. The future of aseptic processing and packaging of foods and beverages will be driven by customer-facing convenience and taste, use of current and new premium clean label natural ingredients, use of multifactorial preservation or hurdle technology for maximizing product quality, and sustainable packaging with claims and messaging.