Download or read book Fragment Based Drug Design written by Lawrence C. Kuo and published by Academic Press. This book was released on 2011-03-09 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD
Download or read book Annual Record of Assessed Valuation of Real Estate in the City of New York written by New York (N.Y.). City Record Office and published by . This book was released on 1904 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Eagle written by and published by . This book was released on 1916 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Liquid Crystals 8 Volume Set written by John W. Goodby and published by John Wiley & Sons. This book was released on 2014-04-14 with total page 5240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much more than a slight revision, this second edition of the successful "Handbook of Liquid Crystals" is completely restructured and streamlined, with updated as well as completely new topics, 100% more content and a new team of editors and authors. As such, it fills the gap for a definitive, single source reference for all those working in the field of organized fluids and will set the standard for the next decade. The Handbook's new structure facilitates navigation and combines the presentation of the content by topic and by liquid-crystal type: A fundamentals volume sets the stage for an understanding of the liquid crystal state of matter, while individual volumes cover the main types and forms, with a final volume bringing together the diverse liquid crystal phases through their applications. This unrivaled, all-embracing coverage represents the undiluted knowledge on liquid crystals, making the Handbook a must-have wherever liquid crystals are investigated, produced or used, and in institutions where their science and technology is taught. Also available electronically on Wiley Online Library, www.wileyonlinelibrary.com/ref/holc Volume 1: Fundamentals of Liquid Crystals Volume 2: Physical Properties and Phase Behavior of Liquid Crystals Volume 3: Nematic and Chiral Nematic Liquid Crystals Volume 4: Smectic and Columnar Liquid Crystals Volume 5: Non-Conventional Liquid Crystals Volume 6: Nanostructured and Amphiphilic Liquid Crystals Volume 7: Supermolecular and Polymeric Liquid Crystals Volume 8: Applications of Liquid Crystals
Download or read book Catalogue of the Harleian Manuscripts in the British Museum written by British museum and published by . This book was released on 1808 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Treatise on Chemistry with Questions on Each Page and a Glossary of Terms Extracted from the Author s Manual of Chemistry written by Richard Dennis Hoblyn and published by . This book was released on 1846 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Report written by United States. Office of Water Resources Research and published by . This book was released on 1965 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Liquid Scripture written by Jeffrey S. Siker and published by Fortress Press. This book was released on 2017-09-01 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The electronic Bible is here to stay‒‒packaged in software on personal computers, available as apps on tablets and cell phones. Increasingly, students look at glowing screens to consult the Bible in class, and congregants do the same in Bible study and worship. Jeffrey S. Siker asks, what difference does it make to our experience of Scripture if we no longer hold a book in our hands, if we again “scroll” through Scripture? How does the “flow” of electronic Scripture change our perception of the Bible’s authority and significance? Siker discusses the difference made when early Christians adopted the codex rather than the scroll and Gutenberg began the mass production of printed Bibles. He also reviews the latest research on how the reading brain processes digital texts and how churches use digital Bibles, including American Bible Society research and his own surveys of church leaders. Siker asks, does the proliferation of electronic translations reduce the perceived seriousness of Scripture? Does it promote an individualistic response to the Bible? How does the change from a physical Bible affect liturgical practice? His synthesis of the advantages and risks of the digitized Bible merit serious reflection in classrooms and churches alike.
Download or read book Love in Vienna written by Barry G. Gale and published by Bloomsbury Publishing USA. This book was released on 2015-11-02 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many decades, critics and supporters of Freudian theory have debated the exact nature of Freud's relationship with his sister-in-law. This book examines the arguments pro and con in light of recently exposed evidence—the first study to do so in depth. For many decades, controversy has surrounded the exact nature of famed psychoanalyst Sigmund Freud's relationship with Minna Bernays, his sister-in-law. Why did Freud and Bernays travel alone together on many occasions? Why did she seem to be so much closer to Freud than his own wife, Martha? The idea that Freud and Minna Bernays had a long-standing affair—an allegation that Freudians typically deny—was first mentioned by Carl Gustav Jung, an early supporter of Freud's and later a critic. Love in Vienna: The Sigmund Freud–Minna Bernays Affair provides the first comprehensive look at the relationship and offers conclusions as to its nature and the implications for Freud's life and work. Organized logically, the book provides background information regarding the two chief antagonists in the story, Sigmund Freud and Carl Gustav Jung. It then presents and critically analyzes arguments for and against there having been an affair. Finally, it looks closely at Freud's relationships with both Minna Bernays and his wife Martha, Minna's sister, and offers conclusions as to the exact nature of Freud's relationship with Bernays. Beyond fascinating those studying Freud or his theories, this work's subject matter and insights will appeal to readers interested in the history of psychology, psychoanalysis, and psychiatry; the intellectual history of Europe; the history of sex and manners; the history of ideas; the fin de siècle period in Vienna; and the history of medicine.
Download or read book A Catalogue of the Harleian Manuscripts in the British Museum written by British Museum. Department of Manuscripts and published by . This book was released on 1808 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Catalogue of the Harleian Manuscripts in the British Museum written by British Library. Department of Manuscripts and published by . This book was released on 1808 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Page s Engineering Weekly written by and published by . This book was released on 1913 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Emerson s Magazine and Putnam s Monthly written by and published by . This book was released on 1858 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Century of Diplomatic Blue Books 1814 1914 written by Lillian M. Penson and published by Psychology Press. This book was released on 1966 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1966. Routledge is an imprint of Taylor & Francis, an informa company.
Download or read book The Dispensatory of the United States of America written by Joseph Price Remington and published by . This book was released on 1918 with total page 2144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Publishers Trade List Annual written by and published by . This book was released on 1883 with total page 2542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
