Download or read book Biocomputing 2006 Proceedings Of The Pacific Symposium written by A Keith Dunker and published by World Scientific. This book was released on 2005-12-08 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2006 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2006 will be held January 3-7, 2006 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference.PSB 2006 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium on Biocomputing 2007 written by Russ Altman and published by World Scientific. This book was released on 2006 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2007 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2007 will be held January 3OCo7, 2007 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference. PSB 2007 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing''s OC hot topics.OCO In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field. Sample Chapter(s). Chapter 1: Protein Interactions and Disease (106 KB). Contents: Protein Interactions and Disease; Computational Approaches to Metabolomics; New Frontiers in Biomedical Text Mining; Biodiversity Informatics: Managing Knowledge Beyond Humans and Model Organisms; Computational Proteomics: High-Throughput Analysis for Systems Biology; DNA-Protein Interactions: Integrating Structure, Sequence, and Function. Readership: Academia and industry in the fields of biocomputing, bioinformatics and computational biology."

Download or read book Pacific Symposium on Biocomputing 2006 written by Russ B. Altman and published by World Scientific Publishing Company Incorporated. This book was released on 2006 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Session introduction / K. Bretonnel Cohen, Olivier Bodenreider, and Lynette Hirschman -- Extraction of gene-disease relations from medline using domain dictionaries and machine learning / Hong-Woo Chun [und weitere] -- Significantly improved prediction of subcellular localization by integrating text and protein sequence data / Annette Höglund [und weitere] -- Evaluation of lexical methods for detecting relationships between concepts from multiple ontologies / Helen L. Johnson [und weitere] -- Automatically generating gene summaries from biomedical literature / Xu Ling [und weitere] -- Finding geneRIFs via gene ontology annotations / Zhiyong Lu, K. Bretonnel Cohen, and Lawrence Hunter -- PhenoGO : assigning phenotypic context to gene ontology annotations with natural language processing / Yves Lussier [und weitere] -- Large-scale testing of bibliome informatics using Pfam protein families / Ana G. Maguitman [und weitere] -- Predicting gene functions from text using a cross-species approach / Emilia Stoica and Marti Hearst -- Bootstrapping the recognition and anaphoric linking of named entities in drosophila articles / Andreas Vlachos [und weitere] -- Session introduction / Robert Stevens, Olivier Bodenreider, and Yves A. Lussier -- Selecting biological data sources and tools with XPR, a path language for RDF / Sarah Cohen-Boulakia, Christine Froidevaux, and Emmanuel Pietriga -- Fast, cheap and out of control : a zero curation model for ontology development / Benjamin M. Good [und weitere] -- Putting semantics into the semantic web : how well can it capture biology? / Toni Kazic -- Event ontology : a pathway-centric ontology for biological processes / Tatsuya Kushida, Toshihisa Takagi, and Ken Ichiro Fukuda -- Discovering biomedical relations utilizing the world-wide web / Sougata Mukherjea and Saurav Sahay -- Biodash : a semantic web dashboard for drug development / Eric K. Neumann and Dennis Quan -- SemBiosphere : a semantic web approach to recommending microarray clustering services / Kevin Y. Yip [und weitere] -- Experience in reasoning with the foundational model of anatomy in OWL DL / Songrnao Zhang, Olivier Bodenreider, and Christine Golbreich -- Session introduction / Bobbie-Jo Webb-Robertson [und weitere] -- A machine learning approach to predicting peptide fragmentation spectra / Randy J. Arnold [und weitere] -- Identifying protein complexes in high-throughput protein interaction screens using an infinite latent feature model / Wei Chu [und weitere] -- High-accuracy peak picking of proteomics data using wavelet techniques / Eva Lange [und weitere] -- Fast De novo peptide sequencing and spectral alignment via tree decomposition / Chunmei Liu [und weitere] -- Experimental design of time series data for learning from dynamic Bayesian networks / David Page and Irene M. Ong -- Finding diagnostic biomarkers in proteomic spectra / Pallavi N. Pratapa, Edward F. Patz, Jr., and Alexander J. Hartemink -- Gaussian mixture modeling of [symbol] helix subclasses : structure and sequence variations / Ashish V. Tendulkar, Babatunde Ogunnaike, and Pramod P. Wangikar -- An SVM scorer for more sensitive and reliable peptide identification via tandem mass spectrometry / Haipeng Wang [und weitere] -- Normalization regarding non-random missing values in high-throughput mass spectrometry data / Pei Wang [und weitere] -- A point-process model for rapid identification of post-translational modifications / Bo Yan [und weitere] -- A new approach for alignment of multiple proteins / Xu Zhang and Tamer Kahveci -- Session introduction / Maricel Kann [und weitere] -- Discovering regulated networks during HIV-1 latency and reactivation / Sourav Bandyopudhyay, Ryan Kelley, and Trey Ideker -- Mining Alzheimer disease relevant proteins from integrated protein interactome data / Jake Yue Chen, Changyu Shen, and Andrey Y. Sivachenko -- Accounting for structural properties and nucleotide co-variations in the quantitative prediction of binding affinities of protein-DNA interactions / Sumedha Gunewardena and Zhaolei Zhang -- Improving computational predictions of cis-regulatory binding sites / Mark Robinson [und weitere] -- Struct2Net : integrating structure into protein-protein interaction prediction / Rohit Singh, Jinbo Xu, and Bonnie Berger -- Identifying interaction sites in "recalcitrant" proteins : predicted protein and RNA binding sites in Rev proteins of HIV-1 and EIAV agree with experimental data / Michael Terribilini [und weitere] -- Modeling and simulation with hybrid functional petri nets of the role of Interleukin-6 in human early haematopoiesis / Sylvie Troncale [und weitere] -- Modeling and analyzing three-dimensional structures of human disease proteins / Yuzhen Ye, Zhanwen Li, and Adam Godzik -- Session introduction / Francisco M. De La Vega [und weitere] -- Relaxing haplotype block models for association testing / Natalie Castellana [und weitere] -- Effect of the Peroxisome Proliferators-Activated Receptor (PPAR) gamma 3 gene on BMI in 1,210 school students from Morelos, Mexico / Lina Chen [und weitere] -- Transferability of tag SNPs to capture common genetic variation in DNA repair genes across multiple populations / Paul I.W. De Bakker [und weitere] -- A tool for selecting SNPs for association studies based on observed linkage disequilibrium patterns / Francisco M. De La Vega, Hadar I. Isaac, and Charles R. Scafe -- Data simulation software for whole-genome association and other studies in human genetics / Scott M. Dudek [und weitere] -- TagSNP selection based on pairwise LD criteria and power analysis in association studies / Shyam Gopalakrishnan and Zhaohui S. Qin -- Efficient two-stage genome-wide association designs based on false positive report probabilities / Peter Kraft -- The whole genome TagSNP selection and transferability among HapMap populations / Reedik Mägi, Lauris Kaplinski, and Maido Remm -- Session introduction / Michelle W. Carrillo, Russell A. Wilke, and Marylyn D. Ritchie -- Class prediction from time series gene expression profiles using dynamical systems kernels / Karsten M. Borgwardt, S.V.N. Vishwanathan, and Hans-Peter Kriegel -- Computational strategy for discovering druggable gene networks from genome-wide RNA expression profiles / Seiya Imoto [und weitere] -- A bivariate functional mapping model for identifying haplotypes that control drug response for systolic and diastolic blood pressures / Min Lin, Rongling Wu, and Julie Johnson -- Risk factor interactions and genetic effects associated with post-operative atrial fibrillation / Alison A. Motsinger [und weitere] -- Learning a predictive model for growth inhibition from the NCI DTP human tumor cell line screening data : does gene expression make a difference? / Lothur Richter, Ulrich Rückert, and Stefan Kramer

Download or read book Pacific Symposium on Biocomputing 2008 written by Russ B. Altman and published by World Scientific. This book was released on 2008 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2008 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2008 will be held on January 4?8, 2008 at the Fairmont Orchid, Big Island of Hawaii. Tutorials will be offered prior to the start of the conference.PSB 2008 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's ?hot topics.? In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium on Biocomputing written by and published by . This book was released on 2008 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biocomputing 2020 Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2019-11-28 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2020 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2020 will be held on January 3 -7, 2020 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2020 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium On Biocomputing 2014 written by Russ B Altman and published by World Scientific. This book was released on 2013-11-19 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2014 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2014 will be held from January 3 - 7, 2014 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2014 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium on Biocomputing 2009 Kohala Coast Hawaii USA 5 9 January 2009 written by Russ Altman and published by World Scientific. This book was released on 2009 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2009 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2009 will be held on January 5OCo9, 2009 in Kamuela, Hawaii. Tutorials will be offered prior to the start of the conference. PSB 2009 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing''s OC hot topics.OCO In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field."

Download or read book Biocomputing 2008 Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2007-12-17 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2008 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2008 will be held on January 4-8, 2008 at the Fairmont Orchid, Big Island of Hawaii. Tutorials will be offered prior to the start of the conference.PSB 2008 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Biocomputing 2007 Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2006-12-11 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2007 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2007 will be held January 3-7, 2007 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference.PSB 2007 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium On Biocomputing 2015 written by Russ B Altman and published by World Scientific. This book was released on 2014-11-11 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2015 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2015 will be held from January 4 - 8, 2015 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2015 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Biocomputing 2017 Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2016-11-23 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2017 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2017 will be held on January 4 - 8, 2017 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2017 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Download or read book Pacific Symposium on Biocomputing 2013 written by Russ Altman and published by World Scientific. This book was released on 2013 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2013 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2013 will be held on January 3 OCo 7, 2013 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2013 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's OC hot topics.OCO In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field."

Download or read book Modern Computational Approaches to Traditional Chinese Medicine written by Zhaohui Wu and published by Elsevier. This book was released on 2012-07-16 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as an essential component of Chinese culture, Traditional Chinese Medicine (TCM) is both an ancient medical system and one still used widely in China today. TCM's independently evolved knowledge system is expressed mainly in the Chinese language and the information is frequently only available through ancient classics and confidential family records, making it difficult to utilize. The major concern in TCM is how to consolidate and integrate the data, enabling efficient retrieval and discovery of novel knowledge from the dispersed data. Computational approaches such as data mining, semantic reasoning and computational intelligence have emerged as innovative approaches for the reservation and utilization of this knowledge system. Typically, this requires an inter-disciplinary approach involving Chinese culture, computer science, modern healthcare and life sciences. This book examines the computerization of TCM information and knowledge to provide intelligent resources and supporting evidences for clinical decision-making, drug discovery, and education. Recent research results from the Traditional Chinese Medicine Informatics Group of Zhejiang University are presented, gathering in one resource systematic approaches for massive data processing in TCM. These include the utilization of modern Semantic Web and data mining methods for more advanced data integration, data analysis and integrative knowledge discovery. This book will appeal to medical professionals, life sciences students, computer scientists, and those interested in integrative, complementary, and alternative medicine. Interdisciplinary book bringing together Traditional Chinese Medicine and computer scientists Introduces novel network technologies to Traditional Chinese Medicine informatics Provides theory and practical examples and case studies of new techniques

Download or read book Evolutionary Computation Machine Learning and Data Mining in Bioinformatics written by Elena Marchiori and published by Springer Science & Business Media. This book was released on 2007-04-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 5th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2007, held in Valencia, Spain, April 2007. Coverage brings together experts in computer science with experts in bioinformatics and the biological sciences. It presents contributions on fundamental and theoretical issues along with papers dealing with different applications areas.

Download or read book Biocomputing 2011 Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2010-11-29 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2011 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2011 will be held on January 3 - 7, 2011 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2011 will bring together top researchers from the US, Asia Pacific, and around the world to exchange research results and address pertinent issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics”. In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly evolving field.

Download or read book Proceedings of the 5th Asia Pacific Bioinformatics Conference written by David Sankoff and published by Imperial College Press. This book was released on 2007 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, and have enabled large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, and gene expression profiles of normal and diseased tissues are being rapidly generated for human and model organisms. Bioinformatics is thus rapidly growing in importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industrial practitioners at the 5th Asia-Pacific Bioinformatics Conference held in Hong Kong in January 2007.