Download or read book Interactions of Bone with Orthopedic Implants and Possible Failures written by Amirhossein Goharian and published by Academic Press. This book was released on 2022-07-20 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue. Explains interactions, along with possible complications of trauma, joint and spinal implants, and failures of the implant and bone tissue Focuses on issues such as bone loss, defects and resorption at the bone and implant interface Includes case studies of implant failures and discusses the mechanical and biological reasons that would cause failure of bone and implant integration

Download or read book Osseointegration of Orthopaedic Implants written by Amirhossein Goharian and published by Academic Press. This book was released on 2019-03-16 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. Reviews and discusses all aspects of orthopedic implant osseointegration Provides conceptual implants for bone fracture fixation and joint replacement Offers novel ideas for the development of orthopedic implants with superior osseointegration

Download or read book Radiology of Orthopedic Implants written by Sanjeev Agarwal and published by Springer. This book was released on 2018-07-29 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an ever-expanding range of implants used in Orthopaedic Surgery. Nearly 200,000 joint replacement procedures are done in UK every year. The performance of these implants is assessed on radiographs. This is of interest to Orthopaedic surgeons and Radiologists alike. Information on interpretation of these radiographs is not readily available in an easily readable format. This book will assist both trainees and practicing orthopedic surgeons and radiologists in assessing the radiologic appearance of implants and their potential for future performance.

Download or read book Mechanical Testing of Orthopaedic Implants written by Elizabeth Friis and published by Woodhead Publishing. This book was released on 2017-05-24 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanical Testing of Orthopaedic Implants provides readers with a thorough overview of the fundamentals of orthopedic implants and various methods of mechanical testing. Historical aspects are presented, along with case studies that are particularly useful for readers. Presents information on a range of implants, from dental to spinal implants Includes case studies throughout that help the reader understand how the content of the book is applied in practice Provides coverage and guidance on FDA regulations and requirements Focuses on application of mechanical testing methods

Download or read book Modularity of Orthopedic Implants written by Donald E. Marlowe and published by ASTM International. This book was released on 1997 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Retrieval and Analysis of Orthopaedic Implants written by Allan Weinstein and published by . This book was released on 1977 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Osseoconductive Surface Engineering for Orthopedic Implants written by Amirhossein Goharian and published by Academic Press. This book was released on 2021-01-26 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process—enabling targeted selection of coatings and technologies to enhance long-term implant–bone integration. Practical and engineering notions in the field of osseoconductive surface engineering are reviewed and discussed using scientific principles and concepts. Engineering cases are analyzed in depth giving a thorough exploration and description of the engineering and scientific concepts for all osseoconductive surface engineering processes. Chapters integrate topics and are organised in such a way as to build on themes and practice.

Download or read book Orthopedic Biomaterials written by Bingyun Li and published by Springer. This book was released on 2018-08-17 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest progress in the biology and manufacturing of orthopedic biomaterials, as well as key industry perspectives. Topics covered include the development of biomaterial-based medical products for orthopedic applications, anti-infection technologies for orthopedic implants, additive manufacturing of orthopedic implants, and more. This is an ideal book for graduate students, researchers and professionals working with orthopedic biomaterials and tissue engineering. This book also: Provides an industry perspective on technologies to prevent orthopedic implant related infection Thoroughly covers how to modulate innate inflammatory reactions in the application of orthopedic biomaterials Details the state-of-the-art research on 3D printed porous bone constructs

Download or read book Shape Memory Implants written by L. Yahia and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shape memory alloy implants or "smart biomaterial" have already been used in humans for 20 years in selected countries. Restrictions in the use of biomaterials in living organisms being reduced throughout the world now the use of SMA implants continue to expand in the fields of vascular and orthopaedic surgery, minimally invasive surgery and drug delivery systems. This book is to provide a state of the art of SMA implants and devices. For the first time long-term clinical experiences and techniques of SMA biocompatibility are presented.

Download or read book Biocompatibility of Orthopedic Implants written by David F. Williams and published by Springer. This book was released on 1982-09-16 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Host Response to Biomaterials written by Stephen F. Badylak and published by Academic Press. This book was released on 2015-05-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices

Download or read book Materials Sciences and Implant Orthopedic Surgery written by R. Kossowsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining experts from the medical and materials sciences, the Institute considered current concepts in medical and materials sciences as they relate to implantable prostheses in orthopedic surgical practice. The syllabus included theory and applications of materials properties, physiological function, and host response to metal and non-metal materials. Total hip prostheses are the most common orthopedic device implanted today involved in over 200,000 operations. Failures occur at the rate of 10~-40~ at ~ to 10 years. Failures are due to loosening, infection, fracture of femoral components, or destruction of the pe 1 vi c components .' All these, and other problems related to the implantation of the devices, the surgical procedures, and device pathology, were. discussed in light of current, as well as, emerging technologies and scientific knowledge. Repeatedly, scientists designing prostheses became aware of a lack of understanding of physiological phenomena associated with biocompatibility; the interchange among practising physicians, basic scientists, and pathologists at this Institute was appreciated. We thank all the contributors and participants for their effort. Thanks are also due to the personnel of the Scientific Affairs Division of NATO. The daily routines of running the Institute were greatly facilitated by the efforts of Pedro Cuevas, M.D, Jose Gutierrez Diaz, M.D, and Dr. Hanita Kossowsky. The devoted help of Nir Kossovsky, M.D, in setting the conference and in editing this book, is sincerely appreci ated.

Download or read book Advances in Materials Science and Implant Orthopedic Surgery written by R. Kossowsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Materials Science and Implant Orthopedic Surgery brings together experts from major university hospitals, materials scientists specializing in bio-materials, and development engineers working for implant manufacturers to address such issues as: mechanisms of fixation; foreign-body immune response; generation and consequences of ionic and wear debris; materials selection, design and manufacturing schemes; and surgical techniques to maximize the safety and efficacy of the devices.

Download or read book Aseptic Loosening of Orthopedic Implants written by Mehdi Amirhosseini and published by Linköping University Electronic Press. This book was released on 2019-05-24 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. Most studies on mechanisms for aseptic loosening investigate wear debris particle-induced osteolysis. However, pathological loading conditions around unstable implants can also trigger osteoclast differentiation and bone loss. In the first study, global gene expression changes induced by mechanical instability of implants, and by titanium particles were compared in a validated rat model for aseptic loosening. Microarray analysis showed that similar signaling pathways and gene expression patterns are involved in particle- and instability-induced periprosthetic osteolysis with an early onset innate immune response as a hallmark of osteolysis induced by mechanical instability. Further, effects of potential therapeutics on restriction of excessive osteoclast differentiation were evaluated. Wnt signaling pathway is known to regulate bone remodeling. In the second study, effects of inactivation of glycogen synthase kinase 3 beta (GSK-3?), a negative regulator of canonical Wnt signaling, on instability-induced periprosthetic osteolysis were examined using our rat model for aseptic loosening. Inhibition of GSK-3? led to a decrease in osteoclast numbers in the periprosthetic bone tissue exposed to mechanical instability while osteoblast perimeter showed an increase. This was accompanied by higher bone volume fraction (BV/TV) in animals treated with the GSK-3? inhibitor. In the third study, potential beneficial effects of two selective inhibitors of cyclindependent kinase 8/19 (CDK8/19) on bone tissue were evaluated. CDK8/19 is a Mediator complex-associated transcriptional regulator involved in several signaling pathways. CDK8/19 inhibitors, mainly under investigation as treatments for tumors, are reported to enhance osteoblast differentiation and bone formation. We show in this study, for the first time, that inhibition of CDK8/19 led to marked suppression of osteoclast differentiation from bone marrow macrophages in vitro through disruption of the RANK signaling. In mouse primary osteoblasts downregulation of osteopontin mRNA, a negative regulator of mineralization, together with increased alkaline phosphatase activity and calcium deposition indicated that osteoblast mineralization was promoted by CDK8/19 inhibition. Moreover, local administration of a CDK8/19 inhibitor promoted cancellous bone regeneration in a rat model for bone healing. These studies contribute to better understanding of mechanisms behind mechanical instability-induced periprosthetic osteolysis and propose potential therapeutics to restrict bone loss with effects on both osteoclasts and osteoblasts.

Download or read book Orthopedic Biomaterials written by Bingyun Li and published by Springer. This book was released on 2018-03-22 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest advances, applications, and challenges in orthopedic biomaterials. Topics covered include materials for orthopedic applications, including nanomaterials, biomimetic materials, calcium phosphates, polymers, biodegradable metals, bone grafts/implants, and biomaterial-mediated drug delivery. Absorbable orthopedic biomaterials and challenges related to orthopedic biomaterials are covered in detail. This is an ideal book for graduate and undergraduate students, researchers, and professionals working with orthopedic biomaterials and tissue engineering. This book also: Describes biodegradable metals for orthopedic applications, such as Zn-based medical implants Thoroughly covers various materials for orthopedic applications, including absorbable orthopedic biomaterials with a focus on polymers Details the state-of-the-art research on orthopedic nanomaterials and nanotechnology

Download or read book The Radiology of Orthopaedic Implants written by Andrew A. Freiberg and published by . This book was released on 2001 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely new atlas features 350 high quality photographs of significant radiologic findings in patients with orthopedic implants. As the only resource dedicated solely to implant radiology, content offers the most comprehensive coverage available on hand and upper extremity, shoulder, hip, knee, spine, foot and ankle, and trauma implants in adults, as well as a special chapter on the use of implants in children. A bevy of expert contributors maintains a tight focus on the needs of the clinician, so every page is useful and to the point. The convenient atlas format also gives clinicians easy access to information. Emphasis is placed on the accurate interpretation of radiographs and the specific language necessary to communicate findings to other specialists. Details of operative techniques and procedures are provided as background where appropriate.

Download or read book Bone Implant Interface in Orthopedic Surgery written by Theofilos Karachalios and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total joint arthroplasty is an effective surgical procedure for end-stage osteoarthritis of major joints with satisfactory long term clinical outcome. A large and growing number of arthroplasties are performed annually worldwide and a great number of orthopaedic surgeons are practicing arthroplasty surgery as their main surgical activity. The biological behavior of the bone-implant interface is crucial for the long term survival of the artificial joint. All factors which have a positive or negative effect on the interface are of great interest for those practicing arthroplasty surgery. Basic scientists and the industry are continuously searching for new implant fixation mechanisms and improved materials. There is an accumulation of a great amount of basic science data (both biological, material and mechanical) related to the incorporation or loosening of the bone-implant interface. However, basic science data does not always translate to satisfactory clinical application, and orthopaedic practitioners often wonder which piece of information is clinically useful. A further problem is that basic scientists often speak their own scientific language and may not fully appreciate common clinical practice needs. In this textbook the biological and mechanical mechanisms of implant incorporation and loosening will be presented. All new data concerning materials and methods for incorporation enhancement will be critically analyzed. Data useful for clinical application will be stressed. Orthopaedic Surgeons will find information which will improve their clinical practice and basic scientists will be helped to understand and appreciate clinical needs.