Download or read book A History of Molecular Biology written by Michel Morange and published by Harvard University Press. This book was released on 2000 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Download or read book Phage and the Origins of Molecular Biology written by John Cairns and published by Firefly Books. This book was released on 1992 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an expanded edition of the landmark collection of 35 essays by pioneers of molecular biology that was first published in 1966 as a 60th birthday tribute to Max Delbruck. The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology..." (Journal of History of Biology). This new edition includes Gunther Stent's obituary of Max Delbruck, two commentaries on issues raised in the book reprinted from Scientific American and Science, and a new preface in which John Cairns reflects on the book's creation and molecular biology's "age of innocence."
Download or read book F lix d Herelle and the Origins of Molecular Biology written by William C. Summers and published by Yale University Press. This book was released on 1999-06-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A self-taught scientist determined to bring science out of the laboratory and into the practical arena, French-Canadian Felix d’Herelle (1873-1949) made history in two different fields of biology. Not only was he first to demonstrate the use and application of bacteria for biological control of insect pests, he also became a seminal figure in the history of molecular biology. This engaging book is the first full biography of d’Herelle, a complex figure who emulated Louis Pasteur and influenced the course of twentieth-century biology, yet remained a controversial outsider to the scientific community. Drawing on family papers, archival sources, interviews, and d’Herelle’s published and unpublished writings, Dr. William C. Summers tells the fascinating story of the scientist’s life and the work that took him around the globe. In 1917, d’Herelle published the first paper describing the phenomenon of the bacteriophage and its biological nature. A series of more than 110 articles and 6 major books followed, in which d’Herelle established the foundation for the later work of the Phage Group in molecular biology. Yet d’Herelle sometimes inspired animosity in others--he was drummed out of the Pasteur Institute, he held only one brief permanent position in the scientific establishment (at Yale University from 1928 to 1933), and he was bewildered by the social nuances of the world of international science. His story is more than the biography of a single brilliant scientist; it is also a fascinating chapter in the history of biology.
Download or read book Origins of Molecular Biology written by Andre Lwoff and published by Elsevier. This book was released on 2012-12-02 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Origins of Molecular Biology: A Tribute to Jacques Monod consists of contributions of scientists narrating their experiences with Jacques Monod. Significantly, the history of various discoveries Jacques Monod made is unfolded. This book pictures Jacques Monod through the eyes of his technician, secretary, peers, friends, and even opponents. It notes that the depiction of the same discovery may be told differently by different scientists who worked at the same time in the same laboratory. The personality of the contributor sometimes influences the narration. Through this book, one can learn how a great scientist receives, discusses, rejects, accepts, assimilates, and creates ideas; how ideas are turned into experiments; how experimental results are interpreted and how concepts are born. In a word, it tells how science is constructed.
Download or read book Origins of Molecular Biology written by Agnès Ullmann and published by . This book was released on 2003 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of contents
Download or read book We Can Sleep Later written by Alfred Day Hershey and published by CSHL Press. This book was released on 2000 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: An absorbing portrait of the pioneering molecular biologist best known for demonstrating that DNA is the genetic component of phages, through essays and reminiscences from twenty–three distinguished scientists whose work and careers were influenced by the man and his science.
Download or read book Operators and Promoters written by Harrison G. Echols and published by Univ of California Press. This book was released on 2024-07-19 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Landmark Experiments in Molecular Biology written by Michael Fry and published by Academic Press. This book was released on 2016-06-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Download or read book The Black Box of Biology written by Michel Morange and published by Harvard University Press. This book was released on 2020-06-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Thinking about Science written by Ernst Peter Fischer and published by W. W. Norton. This book was released on 1988 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The life of the man who studied astronomy, theoretical physics, contributed to genetics, molecular biology, sensory behavior, and evolution and shared the Nobel Prize for Physiology and Medicine
Download or read book A History of Genetics written by Alfred Henry Sturtevant and published by CSHL Press. This book was released on 2001 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.
Download or read book Phage and the Origins of Molecular Biology written by John Cairns and published by CSHL Press. This book was released on 2007 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1966 as a 60th birthday tribute to Max Delbrck, this influential work is republished as "The Centennial Edition." The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle ("Journal of History of Biology").
Download or read book Present at the Flood written by Richard Earl Dickerson and published by Sinauer Associates Incorporated. This book was released on 2005 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Present at the Flood tells the story of the rise of structural molecular biology-proteins and DNA-by immersing the reader in the original papers, written by the scientists who actually did the work. 187 pages from 42 essential scientific papers are reprinted, along with diagrams and commentaries to make them intelligible to the modern reader. The book achieves a personal note because the author was a worker in later years of the field and knew many of the key participants .
Download or read book Crossing the Boundaries of Life written by Karl S. Matlin and published by University of Chicago Press. This book was released on 2022-05-10 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The difficulty of reconciling chemical mechanisms with the functions of whole living systems has plagued biologists since the development of cell theory in the nineteenth century. As Karl Matlin argues in Crossing the Boundaries of Life, it is no coincidence that this longstanding knot of scientific inquiry was loosened most meaningfully by the work of a cytologist, the Nobel laureate Günter Blobel. In 1975, using an experimental setup that did not contain any cells at all, Blobel was able to synthesize proteins to theorize how proteins in the cell communicate spatially, an idea he called signal hypothesis. Over the next 20 years, Blobel and other scientists were able to dissect this process into its precise molecular details. For elaborating his signal concept into a process he termed membrane topogenesis-the idea that each protein in the cell is synthesized with an "address" that directs the protein to its correct destination within the cell-Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999. Matlin argues that Blobel's investigative strategy and its subsequent application addressed the fundamental unresolved dilemma that had bedeviled biology from its very beginning, allowing biology to overcome the barrier that had long blocked progress toward mechanistic explanations of life. Crossing the Boundaries of Life thus uses Blobel's research and life story to shed light on the importance of cell biology for twentieth-century science, illustrating how it propelled the development of adjacent disciplines like biochemistry and molecular biology"--
Download or read book The Evolution of Molecular Biology written by Kensal Van Holde and published by Academic Press. This book was released on 2018-02-20 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances–and an individual’s own research–have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery. Expands on the development of molecular biology from the convergence of two independent disciplines, biochemistry and genetics Discusses the value of molecular biology in a variety of applications Includes research ethics and the societal implications of research Emphasizes the human aspects of research and the consequences of such advances to society
Download or read book The Causes of Molecular Evolution written by John H. Gillespie and published by Oxford University Press. This book was released on 1994-05-26 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.
