Download or read book Organisers Genes written by Conrad Hal Waddington and published by . This book was released on 1940 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conrad Hal Waddington's Organisers and Genes, published in 1940, is a summary of available research and theoretical framework for many concepts related to tissue differentiation in the developing embryo. The book is composed of two main conceptual sections. The first section explores the action and nature of the organizer, while the second section delves into genes and their influence on development. In this book Waddington explored organizers in terms of their capacity and method of induction. First he examined the nature of induction, discussing crucial experiments concerning the organizer, including Hans Spemann's discovery of the organizer, and his own research into organizers in higher birds and mammals. Waddington separated the action of the organizer into two distinct categories, evocation and individuation, discussed below. The main experimental approach discussed in this book involved grafting organizing tissue from one embryo or region of an embryo to another. Waddington described evocation as non-assimilative induction, or a one-way inducing signal. He presented this as a chemical signal and illustrated evocation with the dead organizer experiment. The dead organizer was shown to be capable of inducing differentiation of neural tissue in the ectoderm. He also included chemical induction by estrogens and steroids as other evocative signals. An important aspect of any signal of evocation, as presented by Waddington, is that the signal is specific to the differentiation of a certain tissue type.
Download or read book Organization of the Early Vertebrate Embryo written by Nikolas Zagris and published by Springer Science & Business Media. This book was released on 1995-11-30 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'This book gives many various insights, presented in 26 well-balanced chapters, all highly interesting...We can only highly recommed this book, which is fundamental for all progresses made in the given field.' øCellular and Molecular Biology
Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.
Download or read book From Epigenesis to Epigenetics written by Linda van Speybroeck and published by . This book was released on 2002 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today it is acknowledged that the expression of the genome depends on its intracellular, intercellular, organismic and environmental contexts. This text brings together reflections of researchers in molecular and developmental biology and philosophy of science on this field of biological research.
Download or read book The Sciences of the Artificial reissue of the third edition with a new introduction by John Laird written by Herbert A. Simon and published by MIT Press. This book was released on 2019-08-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herbert Simon's classic work on artificial intelligence in the expanded and updated third edition from 1996, with a new introduction by John E. Laird. Herbert Simon's classic and influential The Sciences of the Artificial declares definitively that there can be a science not only of natural phenomena but also of what is artificial. Exploring the commonalities of artificial systems, including economic systems, the business firm, artificial intelligence, complex engineering projects, and social plans, Simon argues that designed systems are a valid field of study, and he proposes a science of design. For this third edition, originally published in 1996, Simon added new material that takes into account advances in cognitive psychology and the science of design while confirming and extending the book's basic thesis: that a physical symbol system has the necessary and sufficient means for intelligent action. Simon won the Nobel Prize for Economics in 1978 for his research into the decision-making process within economic organizations and the Turing Award (considered by some the computer science equivalent to the Nobel) with Allen Newell in 1975 for contributions to artificial intelligence, the psychology of human cognition, and list processing. The Sciences of the Artificial distills the essence of Simon's thought accessibly and coherently. This reissue of the third edition makes a pioneering work available to a new audience.
Download or read book Philosophy of Developmental Biology written by Marcel Weber and published by Cambridge University Press. This book was released on 2022-04-21 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of developmental biology is interwoven with debates as to whether mechanistic explanations of development are possible or whether alternative explanatory principles or even vital forces need to be assumed. In particular, the demonstrated ability of embryonic cells to tune their developmental fate precisely to their relative position and the overall size of the embryo was once thought to be inexplicable in mechanistic terms. Taking a causal perspective, this Element examines to what extent and how developmental biology, having turned molecular about four decades ago, has been able to meet the vitalist challenge. It focuses not only on the nature of explanations but also on the usefulness of causal knowledge – including the knowledge of classical experimental embryology – for further scientific discovery. It also shows how this causal perspective allows us to understand the nature and significance of some key concepts, including organizer, signal and morphogen. This title is also available as Open Access on Cambridge Core.
Download or read book The Cell Biology of Stem Cells written by Eran Meshorer and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.
Download or read book Darwin s Conjecture written by Geoffrey M. Hodgson and published by University of Chicago Press. This book was released on 2010-12 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: A theoretical study dealing chiefly with matters of definition and clarification of terms and concepts involved in using Darwinian notions to model social phenomena.
Download or read book The Strategy of the Genes written by C.H. Waddington and published by Routledge. This book was released on 2014-04-29 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.
Download or read book Steps to an Ecology of Mind written by Gregory Bateson and published by University of Chicago Press. This book was released on 2000 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gregory Bateson was a philosopher, anthropologist, photographer, naturalist, and poet, as well as the husband and collaborator of Margaret Mead. This classic anthology of his major work includes a new Foreword by his daughter, Mary Katherine Bateson. 5 line drawings.
Download or read book An Introduction to Modern Genetics written by C H (Conrad Hal) 1905- Waddington and published by Legare Street Press. This book was released on 2023-07-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: C.H. Waddington, one of the most prominent geneticists of the twentieth century, provides a clear and concise overview of modern genetics in this landmark book. From DNA to epigenetics, Waddington covers the full breadth of the field, making this an essential read for students and professionals in genetics and related fields. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Download or read book Evolution in Four Dimensions revised edition written by Eva Jablonka and published by MIT Press. This book was released on 2014-03-21 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to reflect the most recent research. This new edition of the widely read Evolution in Four Dimensions has been revised to reflect the spate of new discoveries in biology since the book was first published in 2005, offering corrections, an updated bibliography, and a substantial new chapter. Eva Jablonka and Marion Lamb's pioneering argument proposes that there is more to heredity than genes. They describe four “dimensions” in heredity—four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Jablonka and Lamb present a richer, more complex view of evolution than that offered by the gene-based Modern Synthesis, arguing that induced and acquired changes also play a role. Their lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points. Each chapter ends with a dialogue in which the authors refine their arguments against the vigorous skepticism of the fictional “I.M.” (for Ipcha Mistabra—Aramaic for “the opposite conjecture”). The extensive new chapter, presented engagingly as a dialogue with I.M., updates the information on each of the four dimensions—with special attention to the epigenetic, where there has been an explosion of new research. Praise for the first edition “With courage and verve, and in a style accessible to general readers, Jablonka and Lamb lay out some of the exciting new pathways of Darwinian evolution that have been uncovered by contemporary research.” —Evelyn Fox Keller, MIT, author of Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines “In their beautifully written and impressively argued new book, Jablonka and Lamb show that the evidence from more than fifty years of molecular, behavioral and linguistic studies forces us to reevaluate our inherited understanding of evolution.” —Oren Harman, The New Republic “It is not only an enjoyable read, replete with ideas and facts of interest but it does the most valuable thing a book can do—it makes you think and reexamine your premises and long-held conclusions.” —Adam Wilkins, BioEssays
Download or read book The Influence of Genetics on Contemporary Thinking written by Anne Fagot-Largeault and published by Springer Science & Business Media. This book was released on 2007-11-28 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary volume reflects on the effects of recent discoveries in genetics on a broad range of scientific fields. It shows the way in which those discoveries influence genetics itself and many other fields, and explains the impact of genetics on contemporary culture. The volume contains the most recent views of the Nobel Laureate François Jacob on genetics and the nature of living things.
Download or read book Human Development in the Life Course written by Tania Zittoun and published by Cambridge University Press. This book was released on 2013-11-14 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book shows how individuals develop a unique style or 'melody' of living, beyond physical and social constraints.
Download or read book The Epigenetics of Birds written by Conrad Hal Waddington and published by CUP Archive. This book was released on 1952 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Working With Diagrams written by Lukas Engelmann and published by Berghahn Books. This book was released on 2022-07-08 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arising from the need to go beyond the semiotic, cognitive, epistemic and symbolic reading of diagrams, this book looks at what diagrams are capable of in scholarly work related to the social sciences. Rather than attempting to define what diagrams are, and what their dietic capacity might be, contributions to this volume draw together the work diagrams do in the development of theories. Across a range of disciplines, the chapters introduce the ephemeral dimensions of scientist’s interactions and collaboration with diagrams, consider how diagrams configure cooperation across disciplines, and explore how diagrams have been made to work in ways that point beyond simplification, clarification and formalization.
Download or read book The Evolution of an Evolutionist written by Conrad Hal Waddington and published by . This book was released on 1975 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
