Download or read book Diffuse Optical Tomography written by Huabei Jiang and published by CRC Press. This book was released on 2018-09-03 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an authority involved in the field since its nascent stages, Diffuse Optical Tomography: Principles and Applications is a long-awaited profile of a revolutionary imaging method. Diffuse Optical Tomography (DOT) provides spatial distributions of intrinsic tissue optical properties or molecular contrast agents through model-based reconstruction algorithms using NIR measurements along or near the boundary of tissue. Despite the practical value of DOT, many engineers from electrical or applied mathematics backgrounds do not have a sufficient understanding of its vast clinical applications and portability value, or its uncommon advantages as a tool for obtaining functional, cellular, and molecular parameters. A collection of the author’s research and experience, this book fuses historical perspective and experiential anecdotes with fundamental principles and vital technical information needed to successfully apply this technology—particularly in medical imaging. This reference finally outlines how to use DOT to create experimental image systems and adapt the results of laboratory studies for use in clinical applications including: Early-stage detection of breast tumors and prostate cancer "Real-time" functional brain imaging Joint imaging to treat progressive diseases such as arthritis Monitoring of tumor response New contrast mechanisms and multimodality methods This book covers almost every aspect of DOT—including reconstruction algorithms based on nonlinear iterative Newton methods, instrumentation and calibration methods in both continuous-wave and frequency domains, and important issues of imaging contrast and spatial resolution. It also addresses phantom experiments and the development of various image-enhancing schemes, and it describes reconstruction methods based on contrast agents and fluorescence DOT. Offering a concise description of the particular problems involved in optical tomography, this reference illustrates DOT’s fundamental foundations and the principle of image reconstruction. It thoroughly explores computational methods, forward mathematical models, and inverse strategies, clearly illustrating solutions to key equations.
Download or read book Optical Coherence Tomography written by Mark E. Brezinski and published by Elsevier. This book was released on 2006-08-25 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Coherence Tomography gives a broad treatment of the subject which will include 1)the optics, science, and physics needed to understand the technology 2) a description of applications with a critical look at how the technology will successfully address actual clinical need, and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies. The required mathematical rigor will be present where needed but be presented in such a way that it will not prevent non-scientists and non-engineers from gaining a basic understanding of OCT and the applications as well as the issues of bringing the technology to the market. Optical Coherence Tomography is a new medical high-resolution imaging technology which offers distinct advantages over current medical imaging technologies and is attracting a large number of researchers. Provides non-scientists and non-engineers basic understanding of Optical Coherence Tomography applications and issues.
Download or read book Handbook of Optical Coherence Tomography written by Brett Bouma and published by CRC Press. This book was released on 2019-10-07 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contemporary reference presents a comprehensive review of the most recent applications of optical coherence tomography (OCT) in biology, medicine, engineering, and applied physics-summarizing technological advances that led to the availability of viable imaging tools and modern methods of OCT for optical biopsy, surgical guidance, and quality control of advanced composites in situ.
Download or read book Biomedical Optical Imaging written by James G. Fujimoto and published by Oxford University Press. This book was released on 2009-04-22 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Download or read book Mathematics and Physics of Emerging Biomedical Imaging written by Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging and published by National Academies Press. This book was released on 1996-03-13 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.
Download or read book Optical Coherence Tomography in Glaucoma written by Jullia A. Rosdahl and published by Thieme. This book was released on 2021-09-25 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and user-friendly guide on leveraging OCT for the management of glaucoma Optical coherence tomography (OCT) is a noninvasive diagnostic imaging modality that enables ophthalmologists to visualize different layers of the optic nerve and retinal nerve fiber layer (RNFL) with astounding detail. Today, OCT is an instrumental tool for screening, diagnosing, and tracking the progression of glaucoma in patients. Optical Coherence Tomography in Glaucoma by renowned glaucoma specialist Jullia A. Rosdahl and esteemed contributors is a one-stop, unique resource that summarizes the clinical utility of this imaging technology, from basics to advanced analyses. The book features 14 chapters, starting with introductory chapters that discuss development of OCT and its applications for visualizing the optic nerve and macula. In chapter 5, case studies illustrate OCT imaging of the optic nerve, RNFL, and macula in all stages of glaucoma, from patients at risk to those with mild, moderate, and severe diseases. The next chapters cover the intrinsic relationship between optic nerve structure and function, the use of structure–function maps, and examples of their relationship, followed by a comparison of commonly used devices and a chapter on artifacts. Anterior segment OCT is covered next, followed by chapters covering special considerations in pediatric glaucomas and in patients with high refractive errors. The final chapters cover innovations in OCT on the horizon including OCT angiography, swept-source OCT, and artificial intelligence. Key Highlights Illustrative case examples provide firsthand clinical insights on how OCT can be leveraged to inform glaucoma treatment. In-depth guidance on recognizing and managing artifacts including case examples and key technical steps to help prevent their occurrence. Pearls on the use of OCT for less common patient scenarios such as pediatric glaucomas and high refractive errors. Future OCT directions including angiography, swept-source, and the use of artificial intelligence. This practical resource is essential reading for ophthalmology trainees and ophthalmologists new to using OCT for glaucoma. The pearls, examples, and novel topics in this book will also help experienced clinicians deepen their knowledge and increase confidence using OCT in daily practice.
Download or read book Image Processing in Optical Coherence Tomography Using Matlab written by Robert Koprowski and published by Robert Koprowski. This book was released on 2011 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the results of the creation of methods for ophthalmologists support in OCT images automated analysis. These methods, like the application developed on their basis, are used during routine examinations carried out in hospital. The monograph comprises proposals of new and also of known algorithms, modified by authors, for image analysis and processing, presented on the basis of example of Matlab environment with Image Processing tools. The results are not only obtained fully automatically, but also repeatable, providing doctors with quantitative information on the degree of pathology occurring in the patient. In this case the anterior and posterior eye segment is analysed, e.g. the measurement of the filtration angle or individual layers thickness. To introduce the Readers to subtleties related to the implementation of selected fragments of algorithms, the notation of some of them in the Matlab environment has been given. The presented source code is shown only in the form of example of implementable selected algorithm. In no way we impose here the method of resolution on the Reader and we only provide the confirmation of a possibility of its practical implementation.
Download or read book Handbook of Retinal OCT Optical Coherence Tomography E Book written by Jay S. Duker and published by Elsevier Health Sciences. This book was released on 2021-07-31 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arguably the most important ancillary test available to ophthalmologists worldwide, optical coherence tomography (OCT) has revolutionized the field, and now includes angiographic evaluations (OCTA) that provide vascular flow data without eye injection. Handbook of Retinal OCT is an easy-to-use, high-yield guide to both OCT and OCTA imaging for practitioners at any stage of their career. Highly templated, concise, and portable, this revised edition helps you master the latest imaging methods used to evaluate retinal disease, uveitis, and optic nerve disorders. Helps all health professionals with an interest in OCT to better and more quickly interpret OCT imaging, offering quick, highly visual guidance for evaluating age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and much more. Provides quick answers with bulleted, templated chapters, each focused on one specific diagnosis or group of diagnoses with a particular OCT appearance. Demonstrates how the full spectrum of diseases presents through approximately 400 illustrations, including the highest-quality spectral-domain OCT images available and more than 50 new OCTA images. Includes five new chapters covering optic nerve disease with retinal findings, pachychoroid diseases, paracentral acute middle maculopathy (PAMM), auto-immune retinopathies, and primary uveal lymphoma. Offers clear visual guidance on image patterns with multiple arrows and labels throughout to highlight key details of each disease.
Download or read book Optical Coherence Tomography in Glaucoma written by Ahmet Akman and published by Springer. This book was released on 2018-09-17 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the practical aspects of Optical Coherence Tomography (OCT) in glaucoma diagnostics offering important theoretical information along with many original cases. OCT is a non-invasive imaging technique that acquires high-resolution images of the ocular structures. It enables clinicians to detect glaucoma in the early stages and efficiently monitor the disease. Optical Coherence Tomography in Glaucoma features updated information on technical applications of OCT in glaucoma, reviews recently published literature and provides clinical cases based on Cirrus and Spectralis OCT platforms. In addition, newer techniques like event and trend analyses for progression, macular ganglion cell analysis, and OCT angiography are discussed. This book will serve as a reference for ophthalmologists and optometrists worldwide with a special interest in OCT imaging providing essential guidance on the application of OCT in glaucoma.
Download or read book Handbook of Tissue Optical Clearing written by Valery V. Tuchin and published by CRC Press. This book was released on 2022-02-04 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical photonics is currently one of the fastest growing fields, connecting research in physics, optics, and electrical engineering coupled with medical and biological applications. It allows for the structural and functional analysis of tissues and cells with resolution and contrast unattainable by any other methods. However, the major challenges of many biophotonics techniques are associated with the need to enhance imaging resolution even further to the sub-cellular level as well as translate them for in vivo studies. The tissue optical clearing method uses immersion of tissues into optical clearing agents (OCAs) that reduces the scattering of tissue and makes tissue more transparent and this method has been successfully used ever since. This book is a self-contained introduction to tissue optical clearing, including the basic principles and in vitro biological applications, from in vitro to in vivo tissue optical clearing methods, and combination of tissue optical clearing and various optical imaging for diagnosis. The chapters cover a wide range of issues related to the field of tissue optical clearing: mechanisms of tissue optical clearing in vitro and in vivo; traditional and innovative optical clearing agents; recent achievements in optical clearing of different tissues (including pathological tissues) and blood for optical imaging diagnosis and therapy. This book provides a comprehensive account of the latest research and possibilities of utilising optical clearing as an instrument for improving the diagnostic effectiveness of modern optical diagnostic methods. The book is addressed to biophysicist researchers, graduate students and postdocs of biomedical specialties, as well as biomedical engineers and physicians interested in the development and application of optical methods in medicine. Key features: The first collective reference to collate all known knowledge on this topic Edited by experts in the field with chapter contributions from subject area specialists Brings together the two main approaches in immersion optical clearing into one cohesive book
Download or read book Optical Coherence Tomography in Neurologic Diseases written by Peter A. Calabresi and published by Cambridge University Press. This book was released on 2015-05-14 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive review of the use of optical coherence tomography in neurological diseases for neurologists, neuro-ophthalmologists, and neuroradiologists.
Download or read book Optical Imaging and Microscopy written by Peter Török and published by Springer. This book was released on 2007-08-17 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text on contemporary optical systems is intended for optical researchers and engineers, graduate students and optical microscopists in the biological and biomedical sciences. In three sections, the book discusses high-aperture optical systems, nonlinear optical techniques, and various techniques that are finding new applications. The new second edition has been thoroughly revised and expanded to account for new advances in fluorescence imaging and diffractive optical lenses.
Download or read book Selected Papers on Optical Tomography written by Olaf Minet and published by SPIE-International Society for Optical Engineering. This book was released on 1998 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: SPIE Milestones are collections of seminal papers from the world literature covering important discoveries and developments in optics and photonics.
Download or read book Translational Multimodality Optical Imaging written by Fred S. Azar and published by Artech House. This book was released on 2008 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supported with 119 illustrations, this milestone work discusses key optical imaging techniques in self-contained chapters; describes the integration of optical imaging techniques with other modalities like MRI, X-ray imaging, and PET imaging; provides a software platform for multimodal integration; presents cutting-edge computational and data processing techniques that ensure rapid, cost-effective, and precise quantification and characterization of the clinical data; covers advances in photodynamic therapy and molecular imaging, and reviews key clinical studies in optical imaging along with regulatory and business issues.
Download or read book Advances in Optical Imaging for Clinical Medicine written by Nicusor Iftimia and published by John Wiley & Sons. This book was released on 2011-04-27 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides students, teachers, researchers and clinicians with a strong and established source of information on advanced optical technologies that show real promise of being translated to clinical use.
Download or read book Biomedical Optical Imaging written by James G. Fujimoto and published by Oxford University Press. This book was released on 2009-04-22 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.
